International politics
Resource management
Environmental politics
Polar affairs 

Alger!

Reseach Interests:

My  interest is to discover new bioactive molecules for drug discovery, mainly from marine bacteria. A crucial step in the discovery-process is the identification of known or unknown molecules which is heavily relying on HPLC-HR-MS2. Beside anti-cancer and other pharmaceutically relevant bioactivities, anti-bacterial activity and MoA is a strong interest of mine. Identified candidates are then isolated and their structure is elucidated by NMR. Another project I am working on delas with the screenig of marine rest-raw-material hydrolysates for new neutraceuticals to combat the metabolic syndrome.

At a glance:

HPLC/ Liquid-Chromatography

Analytical and preparative Chemistry

Mass Spectrometry/ HR-MS and Ion mobillity spectroscopy (IMS), Metabolomics

NMR

Natural product druch discovery (anti-cancer, anti-bacterial, anti-inflammatory...)

Investigation of Compounds Molecular Mode of Action

Bioactive Peptides/ Neutraceuticals from Marine Rest-Raw-Material

Peer-reviewed Publications (from year 2003):

1.  Iliev, D. B, Jørgensen, S; Rode, ; Krasnov, A;  Harneshaug, I. & J. B. Jørgensen (2009). CpG-induced secretion of MHCIIb from salmon (Salmo salar) APCs. Developmental & Comparative Immunology. Epub 19. August 2009.
2. Skjaeveland, I., Iliev, D. B., Strandskog, G.& J. B. Jørgensen (2009). Identification and characterization of TLR8 and MyD88 homologs in Atlantic salmon (Salmo salar). Developmental & Comparative Immunology 2009. 33: 1011-1017.
3. Skjæveland,I., D. B. Iliev, & J. B. Jørgensen(2009). Identification and characterization of TLR8 and MyD88 homologs in Atlantic salmon (Salmo salar.) Developmental & Comparative Immunology. 33: 1011-1017
4. Skjesol, A,. Aamo, T,  M.N. Hegseth, Robertsen, B. & J.B. Jørgensen (2009). The interplay between infectious pancreatic necrosis virus (IPNV) and type I IFN. Inhibition of IFN signaling by IPNV proteins VP4 and VP5. Virus Research, 143, 53-60.
5. Hansen,TE, Puntervoll,P, SeternesOM & J B. Jørgensen (2008). Atlantic salmon possess three mitogen activated protein kinase kinase 6 papralogs responding differently to stress. FEBS Journal, 275 4887-4902.  
6. Strandskog, G., Skjæveland, I. Ellingsen & J. B. Jørgensen (2008).Double-stranded RNA and CpG DNA induced immune responses in Atlantic salmon: Comparison and synergies. Vaccine, 26, 4704-4715.
7. Skjæveland,I., D. B. Iliev,J. Zou^, T. Jørgensen & J. B. Jørgensen(2008).  A TLR9 homolog that is up-regulated by IFN- in Atlantic salmon (Salmon salar).Developmental and Comparative Immunology, 32, 603-607.
8. Jørgensen, J. B, A. Johansen, M. N. Hegset, J. Zou,B. Robertsen, & C. J. Secombes (2007).  A recombinant CSHE-214 cell line expressing an Mx1 promoter-reporter system responds to both type I and II interferon from salmonids and represents a versatile tool to study the IFN-system in teleost fish. Fish & Shellfish Immunology, 23, 1294-1303.
9. Røkenes,T. P., A. Skjesol & J.B. Jørgensen (2007). Intermolecular interactionsof infectious pancreas necrosis virus: capsid protein VP3 interacts with dsRNA and the RNA-dependent RNA polymerase VP1. Journal of Virology, 81, 6652-6663.
10. Hansen, T. E. & J.B. Jørgensen (2007). Cloning and characterisation of p38 MAP kinase from Atlantic salmon. A kinase important for regulating salmon TNF-2 and IL-1β expression. Molecular Immunology, 44, 3137-3146.
11. Strandskog, G. T. Ellingsen & J. B. Jørgensen (2007). Characterization of three distinct CpG oligonucleotide classes which differ in ability to induce IFNa/b activity and cell proliferation in Atlantic salmon (Salmo salar L.) leukocytes.Developmental and Comparative Immunology, 31, 39-51.
12. Pedersen, G. M., Johansen, A., Olsen, R. L. & J. B. Jørgensen (2006). Stimulation of anti-viral mechanisms in Atlantic salmon (Salmo salar) leukocytes: synergetic effects of cationic proteins and CpG ODN. Fish and Shellfish Immunology, 20, 203-518.  
13. Johansen, A., Collett, E. B., Sandaker, B;  Secombes, C. J.& Jørgensen, J. B. (2004). Quantification of Atlantic salmon type-I interferon using an Mx1 promoter reporter gene assay. Fish and Shellfish Immunology, 16,173-184.
14. Jørgensen, J. B., L.-H. Johansen, K. Steiro & A. Johansen  (2003).  CpG DNA induces protective antiviral immune responses in Atlantic salmon (Salmo salar L.). Journal of Virology, 77, 11471-1147.    

Invited speaker:

2009:           

Konferansen Frisk Fisk, Bergen, januar 2009: Stimulering av medfødt immunitet - en viktig strategi for nye generasjoner av vaksiner for fisk?                  

 Europharmas Lofoten-seminar, Lofoten juni 2009: Toll-lignende reseptorer: Ny mulighet for økt kontroll av virusinfeksjoner.   

2006           

10th International Congress of ISDCI, Charleston, South Carolina, USA. The use of CpG oligonucleotides as immunstimulants in fish. 

2003           

 Funksjonell genomforskning i Norge: Til å leve av - til å leve med?  NRC, Fuge conference, Oslo, april 2003: Marin funksjonell genomforskning - hvordan sette Norge på verdenskartet? 

2002           

Bioteknologi i primærnæringene - visjon og nytte, Biotechnology program arranged conference at Continental Hotel NRC SAS Hotell, Gardemoen, september 2002: DNA er mer enn gener, spesielle DNA-sekvenser øker motstandsevnen mot sykdom hos laks.

1999           

 Invited speaker at the workshop" Non-specific defence mechanisms of fish". EAFP 9^th International Conference on Diseases of Fish and Shellfish, Rhodes, Greece: The potential use of DNA oligonucleotides as immunostimulants.

Publikasjoner i Frida:

https://www.cristin.no/as/WebObjects/cristin.woa/wa/fres?action=sok&etternavn=J%C3%B8rgensen&fornavn=Jorunn&ar-fra=2003&ar-til=2009&inst=186&erNorsk=1&erNordisk=1&erNasjonalt=1&erInternasjonalt=1&erUkjent=1&visParametre=1&bs=50