Personkort bilde

Veronika K. Pettersen

Førsteamanuensis Institutt for medisinsk biologi
Engelsk flaggikon Samisk flaggikon

Våre symbiotiske tarmmikrober støtter immunforsvaret ved å gi beskyttelse mot patogener. Jeg utforsker metabolske og proteinsignaturer av tarmmikrobiomet for å forstå biokjemiske funksjoner som formidler koloniseringsresistens mot patogener. Jeg studerer hvordan mikrobiomfunksjoner former vår fysiologi, og hvordan vi kan bruke denne kunnskapen til å forebygge sykdommer.

Jeg er prosjektleder for FRIPRO Mobility Research Grant finansiert av Norges forskningsråd. Prosjektet har en tidsramme på tre år (07/2018 til 06/2021) og de to første årene jeg tilbrakte ved University of Calgary, Canada. Prosjektet er et samarbeid mellom mikrobiologer og mikrobiomforskere ved Universitetene i Tromsø og Calgary.

https://www.forskningsradet.no/prosjektbanken/#/project/NFR/274296

MBI-2003

MBI-3014

Førsteamanuensis

Vert-mikrobe interaksjoner og Pediatrisk forskningsgrupper

Centre for New Antibacterial Strategies (https://uit.no/research/cans)

  • van Tilburg Bernardes, Erik; Pettersen, Veronika Kucharova; W. Gutierrez, Mackenzie; Isabelle, Laforest-Lapointe; Marie-Claire, Arrieta. Intestinal fungi are causally implicated in microbiome assembly and immune development in mice. Nature Communications 2020. ISSN 2041-1723.s doi: 10.1038/s41467-020-16431-1.

  • Pettersen, Veronika Kucharova; Steinsland, Hans; Wiker, Harald G. Distinct Metabolic Features of Pathogenic Escherichia coli and Shigella spp. Determined by Label‐Free Quantitative Proteomics. Proteomics 2020. ISSN 1615-9853.s doi: 10.1002/pmic.202000072.

  • Pettersen, Veronika Kucharova; Arrieta, Marie-Claire. Host–microbiome intestinal interactions during early life: considerations for atopy and asthma development. Current Opinion in Allergy and Clinical Immunology 2020. ISSN 1528-4050.s doi: 10.1097/ACI.0000000000000629.

  • Pettersen, Veronika Kucharova; Steinsland, Hans; Wiker, Harald G. Comparative proteomics of enterotoxigenic escherichia coli reveals differences in surface protein production and similarities in metabolism. Journal of Proteome Research 2018; Volum 17 (1). ISSN 1535-3893.s 325 - 336.s doi: 10.1021/acs.jproteome.7b00593.

  • Mohammed, Marwan; Pettersen, Veronika Kucharova; Nerland, Audun Helge; Wiker, Harald G; Bakken, Vidar. Quantitative proteomic analysis of extracellular matrix extracted from mono- and dual-species biofilms of Fusobacterium nucleatum and Porphyromonas gingivalis. Anaerobe 2017; Volum 44. ISSN 1075-9964.s 133 - 142.s doi: 10.1016/j.anaerobe.2017.03.002.

  • Kittang, Bård Reiakvam; Pettersen, Veronika Kucharova; Oppegaard, Oddvar; Skutlaberg, Dag Harald; Dale, Håvard; Wiker, Harald G; Skrede, Steinar. Zoonotic necrotizing myositis caused by Streptococcus equi subsp. zooepidemicus in a farmer. BMC Infectious Diseases 2017; Volum 17:147. ISSN 1471-2334.s 1 - 8.s doi: 10.1186/s12879-017-2262-7.

  • Pettersen, Veronika Kucharova; Mosevoll, Knut Anders; Lindemann, Paul Christoffer; Wiker, Harald G. Coordination of metabolism and virulence factors expression of extraintestinal pathogenic Escherichia coli purified from blood cultures of patients with sepsis. Molecular & Cellular Proteomics 2016; Volum 15 (9). ISSN 1535-9476.s 2890 - 2907.s doi: 10.1074/mcp.M116.060582.

  • Pettersen, Veronika Kucharova; Steinsland, Hans; Wiker, Harald G. Improving genome annotation of enterotoxigenic Escherichia coli TW10598 by a label-free quantitative MS/MS approach. Proteomics 2015; Volum 15 (22). ISSN 1615-9853.s 3826 - 3834.s doi: 10.1002/pmic.201500278.

  • Kucharova, Veronika; Wiker, Harald G. Proteogenomics in microbiology: Taking the right turn at the junction of genomics and proteomics. Proteomics 2014; Volum 14 (23-24). ISSN 1615-9853.s 2360 - 2675.s doi: 10.1002/pmic.201400168.

  • Heggeset, Tonje Marita Bjerkan; Kucharova, Veronika; Nærdal, Ingemar; Valla, Svein; Sletta, Håvard; Ellingsen, Trond Erling; Brautaset, Trygve. Combinatorial Mutagenesis and Selection of Improved Signal Sequences and Their Application for High-Level Production of Translocated Heterologous Proteins in Escherichia coli. Applied and Environmental Microbiology 2013; Volum 79 (2). ISSN 0099-2240.s 559 - 568.s doi: 10.1128/AEM.02407-12.

  • Kucharova, Veronika; Skancke, Jørgen; Brautaset, Trygve; Valla, Svein. Design and optimization of short DNA sequences that can be used as 5' fusion partners for high-level expression of heterologous genes in Escherichia coli. Applied and Environmental Microbiology 2013; Volum 79 (21). ISSN 0099-2240.s 6655 - 6664.s doi: 10.1128/AEM.01676-13.

  • Kucharova, Veronika; Aakvik, Trine; Almaas, Eivind; Naas, Adrian Ertsås; Brautaset, Trygve; Valla, Svein. Non-Invasive Analysis of Recombinant mRNA Stability in Escherichia coli by a Combination of Transcriptional Inducer Wash-Out and qRT-PCR. PLOS ONE 2013; Volum 8 (6). ISSN 1932-6203.s doi: 10.1371/journal.pone.0066429.

  • Balzer, Simone; Kucharova, Veronika; Megerle, Judith; Lale, Rahmi; Brautaset, Trygve; Valla, Svein. A comparative analysis of the properties of regulated promoter systems commonly used for recombinant gene expression in Escherichia coli. Microbial Cell Factories 2013; Volum 12 (26). ISSN 1475-2859.s 1 - 14.s doi: 10.1186/1475-2859-12-26.

  • Berg, Laila; Kucharova, Veronika; Bakke, Ingrid; Valla, Svein; Brautaset, Trygve. Exploring the 5 '-UTR DNA region as a target for optimizing recombinant gene expression from the strong and inducible Pm promoter in Escherichia coli. Journal of Biotechnology 2012; Volum 158 (4). ISSN 0168-1656.s 224 - 230.s doi: 10.1016/j.jbiotec.2011.07.012.

  • Kucharova, Veronika. Expression of recombinant proteins in Escherichia coli: The influence of the nucleotide sequences at the 5´ ends of target genes. 2012 ISBN 978-82-471-3888-5.

  • Kucharova, Veronika. Expression of recombinant proteins in Escherichia coli: The influence of the nucleotide sequences at the 5´ ends of target genes. 2012 ISBN 978-82-471-3888-5.

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