Foto: Gry Berntzen
Gunbjørg Svineng
Dekan
Stillingsbeskrivelse
Dekan Det helsevitenskapelige fakultet
Professor
https://orcid.org/0000-0002-5947-5647
Rabeia Almahmoudi,
Abdelhakim Salem,
Elin Synnøve Hadler-Olsen,
Gunbjørg Svineng,
Tuula Salo,
Ahmed Al-Samadi
:
The effect of interleukin-17F on vasculogenic mimicry in oral tongue squamous cell carcinoma
Sini Karinen,
Krista Juurikka,
Roosa Hujanen,
Wafa Whabi,
Elin Synnøve Hadler-Olsen,
Gunbjørg Svineng
m.fl.:
Tumour cells express functional lymphatic endothelium-specific hyaluronan receptor in vitro and in vivo: Lymphatic mimicry promotes oral oncogenesis?
Synnøve Norvoll Magnussen,
Jimita Prashant Toraskar,
Elin Synnøve Hadler-Olsen,
Tonje S. Steigedal,
Gunbjørg Svineng
:
Nephronectin as a matrix effector in cancer
Synnøve Norvoll Magnussen,
Jimita Prashant Toraskar,
Imola Wilhelm,
Janos Hasko,
Stine Figenschau,
Judit Molnar
m.fl.:
Nephronectin promotes breast cancer brain metastatic colonization via its integrin-binding domains
Rangita Dawadi,
Nabin Malla,
Beate Hegge,
Imin Wushur,
Eli Berg,
Gunbjørg Svineng
m.fl.:
Molecular Interactions Stabilizing the Promatrix Metalloprotease-9·Serglycin Heteromer
Jimita Prashant Toraskar,
Synnøve Norvoll Magnussen,
Lars Hagen,
Animesh Sharma,
Linh Hoang,
Geir Bjørkøy
m.fl.:
A Novel Truncated Form of Nephronectin Is Present in Small Extracellular Vesicles Isolated from 66cl4 Cells
Samantha Marie Solon-Biet,
Victoria Carroll Cogger,
Tamara Pulpitel,
Devin Wahl,
Ximonie Clark,
Elena E. Bagley
m.fl.:
Branched-chain amino acids impact health and lifespan indirectly via amino acid balance and appetite control
Nature Metabolism 2019 DOI
Jimita Prashant Toraskar,
Synnøve Magnussen,
Konika Chawla,
Gunbjørg Svineng,
Tonje S. Steigedal
:
Nephronectin mediates p38 MAPK‐induced cell viability via its integrin binding enhancer motif
Ingebrigt Sylte,
Rangita Dawadi,
Nabin Malla,
Susannah von Hofsten,
Tra-Mi Nguyen,
Ann Iren Solli
m.fl.:
The selectivity of galardin and an azasugar-based hydroxamate compound for human Matrix metalloproteases and bacterial metalloproteases
Tonje S. Steigedal,
Jimita Prashant Toraskar,
Richard P. Redvers,
Marit Valla,
Synnøve Magnussen,
Anna M. Bofin
m.fl.:
Nephronectin is Correlated with Poor Prognosis in Breast Cancer and Promotes Metastasis via its Integrin-Binding Motifs
Pirjo Åström,
Krista Juurikka,
Elin Synnøve Hadler-Olsen,
Gunbjørg Svineng,
Nilva K. Cervigne,
Ricardo D. Coletta
m.fl.:
The interplay of matrix metalloproteinase-8, transforming growth factor-β1 and vascular endothelial growth factor-C cooperatively contributes to the aggressiveness of oral tongue squamous cell carcinoma
Synnøve Magnussen,
Elin Synnøve Hadler-Olsen,
Daniela Elena Costea,
Eli Berg,
Cristiane de Albuquerque Cavalcanti Jacobsen,
Bente Mortensen
m.fl.:
Cleavage of the urokinase receptor (uPAR) on oral cancer cells: Regulation by transforming growth factor - beta1 (TGF-beta1) and potential effects on migration and invasion
Oddveig G Rikardsen,
Synnøve Magnussen,
Gunbjørg Svineng,
Elin Synnøve Hadler-Olsen,
Lars Uhlin-Hansen,
Sonja Eriksson Steigen
:
Plectin as a prognostic marker in non-metastatic oral squamous cell carcinoma
Synnøve Magnussen,
Elin Synnøve Hadler-Olsen,
Nadezhda Latysheva,
Emma Pirila,
Sonja Eriksson Steigen,
Robert Hanes
m.fl.:
Tumour Microenvironments Induce Expression of Urokinase Plasminogen Activator Receptor (uPAR) and Concomitant Activation of Gelatinolytic Enzymes
Synnøve Magnussen,
Oddveig G Rikardsen,
Elin Synnøve Hadler-Olsen,
Lars Uhlin-Hansen,
Sonja Eriksson Steigen,
Gunbjørg Svineng
:
Urokinase Plasminogen Activator Receptor (uPAR) and Plasminogen Activator Inhibitor-1 (PAI-1) are potential predictive biomarkers in early stage Oral Squamous Cell Carcinomas (OSCC)
Nabin Malla,
Eli Berg,
Achilleas D. Theocharis,
Gunbjørg Svineng,
Lars Uhlin-Hansen,
Jan-Olof Winberg
:
Invitro reconstitution of complexes between pro-matrix metalloproteinase-9 and the proteoglycans serglycin and versican
The FEBS Journal 2013 DOI
Chandra Sekhar Ravuri,
Gunbjørg Svineng,
nils-erik Huseby
:
Differential regulation of gamma-glutamyltransferase and glutamate cysteine ligase expression after mitochondrial uncoupling: gamma-glutamyltransferase is regulated in an Nrf2- and NF kappa B-independent manner
Free radical research 2013 DOI
Bodil Irene Fadnes,
Anne Husebekk,
Gunbjørg Svineng,
Øystein Rekdal,
Masaki Yanagishita,
Svein Olav Kolset
m.fl.:
The proteoglycan repertoire of lymphoid cells
Dominik Ausbacher,
Gunbjørg Svineng,
Terkel Hansen,
Morten B. Strøm
:
Anticancer mechanisms of action of two small amphipathic beta(2,2)-amino acid derivatives derived from antimicrobial peptides
Biochimica et Biophysica Acta - Biomembranes 19. juli 2012 DOI
Gunbjørg Svineng,
Synnøve Magnussen,
Elin Synnøve Hadler-Olsen
:
Plasmin and the plasminogen activator system in health and disease
Walter de Gruyter (De Gruyter) 2012 DOI
Chandra Sekhar Ravuri,
Gunbjørg Svineng,
Serhiy Pankiv,
nils-erik Huseby
:
Endogenous production of reactive oxygen species by the NADPH oxidase complexes is a determinant of gamma gamma-glutamyltransferase expression
Free radical research 2011 DOI
Elin Synnøve Hadler-Olsen,
Hilde Ljones,
Chandra Sekhar Ravuri,
Ahmad Omair,
Oddveig G Rikardsen,
Gunbjørg Svineng
m.fl.:
Organ specific regulation of tumour invasiveness and gelatinolytic activity at the invasive front
European Journal of Cancer 2011 DOI
Hilde Ljones,
Elin Synnøve Hadler-Olsen,
Synnøve Magnussen,
Oddveig G Rikardsen,
sonja eriksson Steigen,
elisabeth Sundkvist
m.fl.:
S100A4 Expression in Xenograft Tumors of human carcinoma cell lines is induced by the tumor microenvironment
American Journal of Pathology 2011 DOI
Elin Synnøve Hadler-Olsen,
Premasany Kanapathippillai,
Eli Berg,
Gunbjørg Svineng,
Jan-Olof Winberg,
Lars Uhlin-Hansen
:
Gelatin In Situ Zymography on Fixed, Paraffin-embedded Tissue: Zinc and Ethanol Fixation Preserve Enzyme Activity
Journal of Histochemistry and Cytochemistry 2010 DOI
Elin Synnøve Hadler-Olsen,
Hilde Ljones,
Oddveig G Rikardsen,
Sonja Eriksson Steigen,
Premasany Kanapathippillai,
Reidar Grenman
m.fl.:
Stromal impact on tumor growth and lymphangiogenesis in human carcinoma xenografts
nils-erik Huseby,
elisabeth Sundkvist,
Gunbjørg Svineng
:
Glutathione and Sulfur Containing Amino Acids: Antioxidant and Conjugation Activities
John Wiley & Sons 2009
Atle Noralf Larsen,
Terese Solstad,
Gunbjørg Svineng,
Marit Seppola,
Trond Ø. Jørgensen
:
Molecular characterisation of a goose-type lysozyme gene in Atlantic cod (Gadus morhua L.)
Fish and Shellfish Immunology 2009 DOI
Renate Elenjord,
Jasmine Blue Allen,
Harald Thidemann Johansen,
Harald T. Johansen,
hanne Kildalsen,
Gunbjørg Svineng
m.fl.:
Collagen I regulates matrix metalloproteinase-2 activation in osteosarcoma cells independent of S100A4
The FEBS Journal 2009 DOI
Gunbjørg Svineng,
Chandra Sekhar Ravuri,
Oddveig G Rikardsen,
Nils-Erik Huseby,
Jan-Olof Winberg
:
The role of reactive oxygen species in integrin and matrix metalloproteinase expression and function
Connective Tissue Research 2008 DOI
Eva Sjøttem,
Cecilie Rekdal,
Gunbjørg Svineng,
Sylvia sagen Johnsen,
Helle Bagterp Klenow,
Rebecca dale Uglehus
m.fl.:
The ePHD protein SPBP interacts with TopBP1 and together they co-operate to stimulate Ets1-mediated transcription
Nucleic Acids Research (NAR) 2007 DOI
Synnøve Magnussen,
Jimita Prashant Toraskar,
Imola Wilhelm,
Janos Hasko,
Stine Figenschau,
Judith Molnar
m.fl.:
Nephronectin promotes breast cancer brain metastatic colonization via its integrin-binding domains
2018
Synnøve Magnussen,
Jimita Prashant Toraskar,
Imola Wilhelm,
Janos Hasko,
Stine Figenschau,
Judith Molnar
m.fl.:
Nephronectin (Npnt) promotes breast cancer brain metastasis via its integrin binding domains
2017
Synnøve Magnussen,
Imola Wilhelm,
Janos Hasko,
Judith Molnar,
Marit Seppola,
Elin Synnøve Hadler-Olsen
m.fl.:
The metastasis-promoting protein Nephronectin
2016
Gunbjørg Svineng,
Terje Steinar Larsen
:
Bli ekspert på menneskekroppen og få en trygg og viktig jobb!
2015
Anna Maria Wirsing,
Ann Iren Solli,
Gunbjørg Svineng,
Jan-Olof Winberg,
Elin Synnøve Hadler-Olsen
:
Intracellular Matrix Metalloproteinase-2 in skeletal muscle: effect of glucose and oxidative stress
2015
Anna Maria Wirsing,
Ann Iren Solli,
Gunbjørg Svineng,
Jan-Olof Winberg,
Elin Synnøve Hadler-Olsen
:
Intracellular Matrix Metalloproteinase-2 in skeletal muscle - a 3D skeletal muscle tissue engineering approach -
2015
Tonje Strømmen Steigedal,
Richard Redvers,
Bedrich Eckhardt,
John Michael Lamar,
Judy Doherty,
Richard O. Hynes
m.fl.:
The extracellular matrix protein Nephronectin (Npnt) promotes metastasis via its integrin binding domains
2014
Tonje Steigedal,
Gunbjørg Svineng,
Richard Redvers,
Bedrich Eckhardt,
John M. Lamar,
Judy Doherty
m.fl.:
Cellular interactions with the extracellular matrix of tumor microenvironment
2013
Gunbjørg Svineng,
Synnøve Magnussen,
Elin Synnøve Hadler-Olsen,
Nadezhda Latysheva,
Emma Pirila,
Sonja Eriksson Steigen
m.fl.:
Stromal induced expression of uPAR
2013
Dominik Ausbacher,
Terkel Hansen,
Gunbjørg Svineng,
Morten B. Strøm
:
Mechanisms of cancer cell death induced by two novel cationic beta-peptidomimetics
Biopolymers 2011
Elin Synnøve Hadler-Olsen,
Chandra Sekhar Ravuri,
Hilde Ljones Wetting,
Oddveig G Rikardsen,
sonja eriksson Steigen,
Gunbjørg Svineng
m.fl.:
Stromal Impact on Tumor Invasiveness and Gelatinolytic Activity at the Invasive Front
2011
Richard Redvers,
Gunbjørg Svineng,
Bedrich Eckhardt,
Normand Pouliot,
Keith Stanley,
Louis Reichardt
m.fl.:
The role of the extracellular matrix molecule Nephronectin/POEM in breast cancer metastasis
2011
Dominik Ausbacher,
Terkel Hansen,
Gunbjørg Svineng,
Morten B. Strøm
:
Mechanisms of cancer cell death induced by two novel cationic β-peptidomimetics
2011
Elin Synnøve Hadler-Olsen,
Chandra Sekhar Ravuri,
Hilde Ljones,
Oddveig G Rikardsen,
sonja eriksson Steigen,
Gunbjørg Svineng
m.fl.:
Organ specific stromal influence on tumor invasiveness and proteolytic activity at the invasive front
European Journal of Cancer 2010 DOI
Elin Synnøve Hadler-Olsen,
Hilde Ljones,
O Rikardsen,
sonja eriksson Steigen,
Jan-Olof Winberg,
Gunbjørg Svineng
m.fl.:
Stromal impact on tumor growth and lymphangiogenesis in human carcinoma xenografts
APMIS - Journal of Pathologiy, Microbiology and Immunology 2010
Stian Sjøli,
Olayiwola Adekoya,
Yang Jiang,
O Akselsen,
VT Hansen,
Gunbjørg Svineng
m.fl.:
Novel Inhibitors of Matrix Metalloprotease-9 and-14
The FEBS Journal 2010
Atle Noralf Larsen,
Ronny Helland,
Gunbjørg Svineng,
Trond Ø. Jørgensen
:
Identification, cloning and recombinant expression of a goose-type lysozyme from Atlantic cod (Gadus Morhua)
2007
Chandra Sekhar Ravuri,
Synnøve Magnussen,
Jan-Olof Winberg,
Nils-Erik Huseby,
Gunbjørg Svineng
:
The effect of elevated levels of reactive oxygen species on oral squamous carcinoma cell adhesion and invasion
2007
Gunbjørg Svineng
:
Genetic modifications of oral cancer cell lines
2006
Eva Sjøttem,
Helle Bagterp Klenow,
Cecilie Rekdal,
Gunbjørg Svineng,
Sylvia Sagen Johnsen,
Rebecca Dale Uglehus
m.fl.:
SPBP and TopBP1: Modulators of Androgen Receptor Activity
2006
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Forskningsinteresser
Tumorbiology
Extracellular matrix degrading enzymes; uPAR and MMPs
Cell adhesion molecules; Integrins
Extracellular matrix proteins; Nephronectin
Metastasis related proteins; S100A4
Medlem i forskningsgruppe
CV
Instituttleder ved Institutt for medisinsk biologi, Det Helsevitenskapelige fakultet, fra 1.08.2017
Forskningsopphold ved Sydney University, Charles Perkins Center or ANZAC Research Institute, Australia, 2016-2017.
Forskningsgruppeleder Tumorbiologisk forskningsgruppe, 2015-2016.
Forskningsopphold ved Peter MacCallum Cancer Centre, Melbourne, Australia, 2010-2011.
Undervisningsansvarlig IMB, 2009-2016.
Avdelingsleder Medisinsk biokjemi, IMB, 2006-2009.
Førsteamanuensis i medisinsk biokjemi, IMB fra 2005.
Forsker i Marin bioteknologi, Norges Fiskerihøyskole, 2004-2005.
Postdoc. i Molekylær kreftforskning, Biokjemisk avdeling, IMB, lønnet av Kreftforeningen, 2001-2004. Prosjekt: SPBP
Doktorgrad i 1999 i Medicinsk Vetenskap fra Institutionen för Medicinsk Biokemi och Mikrobiologi, Medicinska fakultetet, Uppsala Universitet, Sverige.
Cand.scient i 1993 i Molekylærbiologi ved Biokjemisk avdeling, Institutt for Medisinsk Biologi, UiT.