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  3. Jorunn Jørgensen
Bilde av Jørgensen, Jorunn
Bilde av Jørgensen, Jorunn
Professor Norges fiskerihøgskole jorunn.jorgensen@uit.no +4777646716 Her finner du meg

Jorunn Jørgensen

Stillingsbeskrivelse

  • Thomais Tsoulia, Arvind Sundaram, Stine Braaen, Jorunn B Jørgensen, Espen Rimstad, Øystein Wessel m.fl.:
    Transcriptomics of early responses to purified Piscine orthoreovirus-1 in Atlantic salmon (Salmo salar L.) red blood cells compared to non-susceptible cell lines
    Frontiers in Immunology 2024 ARKIV / DOI
  • Shiferaw Jenberie, Yorick Andreas van der Wal, Ingvill Jensen, Jorunn B Jørgensen :
    There and back again? A B cell's tale on responses and spatial distribution in teleosts
    Fish and Shellfish Immunology 2024 ARKIV / DOI
  • Shiferaw Jenberie, Henriette R. Nordli, Guro Strandskog, Linn Greiner-Tollersrud, Ma Michelle Demogina Penaranda, Jorunn B Jørgensen m.fl.:
    Virus-specific antibody secreting cells reside in the peritoneal cavity and systemic immune sites of Atlantic salmon (Salmo salar) challenged intraperitoneally with salmonid alphavirus
    Developmental and Comparative Immunology 2024 ARKIV / DOI
  • Yorick Andreas van der Wal, Henriette R. Nordli, Allan Akandwanaho, Linn Greiner-Tollersrud, Jaap Kool, Jorunn B Jørgensen :
    CRISPR-Cas– induced IRF3 and MAVS knockouts in a salmonid cell line disrupt PRR signaling and affect viral replication
    Frontiers in Immunology 2023 ARKIV / DOI
  • Yorick Andreas van der Wal, Shiferaw Jenberie, Henriette Nordli, Linn Greiner-Tollersrud, Jaap Kool, Ingvill Jensen m.fl.:
    The importance of the Atlantic salmon peritoneal cavity B cell response: Local IgM secreting cells are predominant upon Piscirickettsia salmonis infection
    Developmental and Comparative Immunology 2021 ARKIV / DOI
  • Dimitar Borisov Iliev, Guro Strandskog, Mehrdad Sobhkhez, Jack-Ansgar Bruun, Jorunn B Jørgensen :
    Secretome Profiling of Atlantic Salmon Head Kidney Leukocytes Highlights the Role of Phagocytes in the Immune Response to Soluble β-Glucan
    Frontiers in Immunology 2021 ARKIV / DOI
  • Muhammad Salman Malik, Lena Hammerlund Teige, Stine Braaen, Anne Berit Olsen, Monica Nordberg, Marit Måsøy Amundsen m.fl.:
    Piscine Orthoreovirus (PRV)-3, but Not PRV-2, Cross-Protects against PRV-1 and Heart and Skeletal Muscle Inflammation in Atlantic Salmon
    Vaccines 2021 ARKIV / DOI
  • Shiferaw Jenberie, Ma Michelle Demogina Penaranda, Hanna Leena Thim, Morten Bay Styrvold, Guro Strandskog, Jorunn B Jørgensen m.fl.:
    Salmonid Alphavirus Subtype 3 Induces Prolonged Local B Cell Responses in Atlantic Salmon (Salmo salar) After Intraperitoneal Infection
    Frontiers in Immunology 2020 ARKIV / DOI
  • Arpita Nepal, Deanna Wolfson, Balpreet Singh Ahluwalia, Ingvill Jensen, Jorunn B Jørgensen, Dimitar Borisov Iliev :
    Intracellular distribution and transcriptional regulation of Atlantic salmon (Salmo salar) Rab5c, 7a and 27a homologs by immune stimuli
    Fish and Shellfish Immunology 2020 ARKIV / DOI
  • Lena Hammerlund Teige, Ida Aksnes, Magnus Vikan Røsæg, Ingvill Jensen, Jorunn Jørgensen, Hilde Sindre m.fl.:
    Detection of specific Atlantic salmon antibodies against salmonid alphavirus using a bead-based immunoassay
    Fish and Shellfish Immunology 2020 ARKIV / DOI
  • Dennis Bela-Ong, Linn Greiner-Tollersrud, Yorick Andreas van der Wal, Ingvill Jensen, Ole Morten Seternes, Jorunn Jørgensen :
    Infection and microbial molecular motifs modulate transcription of the interferon-inducible gene ifit5 in a teleost fish
    Developmental and Comparative Immunology 2020 ARKIV / DOI
  • Dimitar Borisov Iliev, Leidy Lagos, Hanna Leena Thim, Sven Martin Jørgensen, Aleksei Krasnov, Jorunn B Jørgensen :
    CpGs Induce Differentiation of Atlantic Salmon Mononuclear Phagocytes Into Cells With Dendritic Morphology and a Proinflammatory Transcriptional Profile but an Exhausted Allostimulatory Activity
    Frontiers in Immunology 2019 ARKIV / DOI
  • Steingrim Svenning, Agata Teresa Wyrozemska, Yorick Andreas van der Wal, Børre Robertsen, Ingvill Jensen, Jorunn B Jørgensen m.fl.:
    Microbial danger signals control transcriptional induction of distinct MHC class I L lineage genes in Atlantic salmon
    Frontiers in Immunology 2019 ARKIV / DOI
  • Maria Dahle, Jorunn B Jørgensen :
    Antiviral defense in salmonids – Mission made possible?
    Fish and Shellfish Immunology 2019 ARKIV / DOI
  • Ma Michelle Demogina Penaranda, Ingvill Jensen, Linn Greiner-Tollersrud, Jack-Ansgar Bruun, Jorunn B Jørgensen :
    Profiling the Atlantic Salmon IgM+ B Cell Surface Proteome: Novel Information on Teleost Fish B Cell Protein Repertoire and Identification of Potential B Cell Markers
    Frontiers in Immunology 2019 ARKIV / FULLTEKST / DOI
  • Dimitar Borisov Iliev, Guro Strandskog, Arpita Nepal, Augusta Hlin Aspar Sundbø, Randi Olsen, Jorunn B Jørgensen m.fl.:
    Stimulation of exosome release by extracellular DNA is conserved across multiple cell types
    The FEBS Journal 28. juni 2018 ARKIV / DOI
  • Shiferaw Jenberie, Hanna Leena Thim, J Oriol Sunyer, Karsten Skjødt, Ingvill Jensen, Jorunn B Jørgensen :
    Profiling Atlantic salmon B cell populations: CpG-mediated TLR-ligation enhances IgM secretion and modulates immune gene expression
    Scientific Reports 2018 ARKIV / DOI
  • Mehrdad Sobhkhez, Lisbeth Lindenskov Joensen, Linn Greiner-Tollersrud, Guro Strandskog, Hanna Leena Thim, Jorunn B Jørgensen :
    A conserved inhibitory role of suppressor of cytokine signaling 1 (SOCS1) in salmon antiviral immunity
    Developmental and Comparative Immunology 2016 DOI
  • Kjersti Julin, Lill-Heidi Johansen, Ann-Inger Sommer, Jorunn B Jørgensen :
    Persistent infections with infectious pancreatic necrosis virus (IPNV) of different virulence in Atlantic salmon, Salmo salar L
    Journal of Fish Diseases 2015 DOI
  • Lill-Heidi Johansen, Hanna Leena Thim, Sven Martin Jørgensen, Sergey Afanasyev, Guro Strandskog, Torunn Taksdal m.fl.:
    Comparison of transcriptomic responses to pancreas disease (PD) and heart and skeletal muscle inflammation (HSMI) in heart of Atlantic salmon (Salmo salar L)
    Fish and Shellfish Immunology 2015 DOI
  • Jorunn B Jørgensen :
    The innate immune response in fish
    Wiley-Blackwell 2014 DOI
  • Stephen Mutoloki, Jorunn B Jørgensen, Øystein Evensen :
    The adaptive immune response in fish
    Wiley-Blackwell 2014 DOI
  • Mehrdad Sobhkhez, Astrid Skjesol, Ernst Ivan Thomassen, Dimitar Borisov Iliev, Baojian Sun, Børre Robertsen m.fl.:
    Structural and functional characterization of salmon STAT1, STAT2 and IRF9 homologs sheds light on interferon signaling in teleosts
    FEBS Open Bio 2014 ARKIV / DOI
  • Astrid Skjesol, Liebe Thomas de Regt, Dimitar Borisov Iliev, Ernst Ivan Thomassen, Linn Greiner-Tollersrud, Mehrdad Sobhkhez m.fl.:
    Functional conservation of suppressors of cytokine signaling proteins between teleosts and mammals: Atlantic salmon SOCS1 binds to JAK/STAT family members and suppresses type I and II IFN signaling
    Developmental and Comparative Immunology 2014 DOI
  • Hanna Leena Thim, Stéphane Villoing, Marian F McLoughlin, Karen Elina Cristie, Søren Grove, Petter Frost m.fl.:
    Vaccine adjuvants in fish vaccines make a difference: comparing the effects of three adjuvants (Montanide ISA763A oil, CpG/poly I:C combo and VHSV glycoprotein) used alone or in combination to formulate an inactivated salmonid alphavirus whole virus antigen
    Vaccines 2014 ARKIV / DOI
  • Dimitri Borisov Iliev, Hanna Leena Thim, Leidy Lagos, randi Olsen, Jorunn B Jørgensen :
    Homing of Antigen-Presenting Cells in Head Kidney and Spleen – Salmon Head Kidney Hosts Diverse APC Types
    Frontiers in Immunology 2013 ARKIV / DOI
  • Mehrdad Sobhkhez, Tom Egil Hansen, Dimitri Borisov Iliev, Astrid Skjesol, Jorunn B Jørgensen :
    The Atlantic salmon protein tyrosine kinase Tyk2: Molecular cloning, modulation of expression and function
    Developmental and Comparative Immunology 2013 DOI
  • Dimitri Borisov Iliev, Tom Egil Hansen, Sven Martin Jørgensen, Aleksei Krasnov, Jorunn B Jørgensen :
    CpG- and LPS-activated MAPK signaling in in vitro cultured salmon (Salmo salar) mononuclear phagocytes
    Fish and Shellfish Immunology 2013 ARKIV / DOI
  • Dimitar Borisov Iliev, ingrid SkjÆveland, Jorunn B Jørgensen :
    CpG oligonucleotides bind TLR9 and RRM-Containing proteins in Atlantic Salmon (Salmo salar)
    BMC Immunology 2013 ARKIV / DOI
  • Søren Grove, Lars Austbø, Kjartan Hodneland, Petter Frost, Marie Therese Løvoll, Marian F McLoughlin m.fl.:
    Immune parameters correlating with reduced susceptibility to pancreas disease in experimentally challenged Atlantic salmon (Salmo salar)
    Fish and Shellfish Immunology 2013 DOI
  • Leidy Lagos, Dimitar Borisov Iliev, Ronny Helland, Mario Rosemblatt, Jorunn B Jørgensen :
    CD40L-A costimulatory molecule involved in the maturation of antigen presenting cells in Atlantic salmon (Salmo salar)
    Developmental and Comparative Immunology 2012 DOI
  • Monica Nordberg, Maria Dahle, Jorunn B Jørgensen, Øystein Wessel :
    Specific antibody responses (IgM) against Piscine orthoreovirus (PRV) in Atlantic salmon (Salmo salar), measured in a multiplexed magnetic bead-based system
    2021
  • Muhammad Salman Malik, Lena Hammerlund Teige, Stine Braaen, Anne Berit Olsen, Monica Nordberg, Marit Måsøy Amundsen m.fl.:
    PRV-3, but not PRV-2, cross-protects against PRV-1 and HSMI in Atlantic salmon
    2021
  • Sunniva Katharina Thode, Jorunn B Jørgensen :
    Også laks produserer sin egen brems mot virussmitte
    30. juli 2020 FULLTEKST
  • Jorunn Jørgensen, Maria Dahle :
    Virus og vert: Hvordan forsvarer oppdrettslaksen seg mot virus?
    Naturen 2020 DOI
  • Ma Michelle Demogina Penaranda, Mikael Fjeld Wold, Ingvill Jensen, Jorunn B Jørgensen :
    The role of TNF superfamily ligands, BAFF AND APRIL, in the immune response of Atlantic salmon
    2019
  • Ma Michelle Demogina Penaranda, Mikael Fjeld Wold, Shiferaw Jenberie, Ingvill Jensen, Jorunn B Jørgensen :
    Investigation on the role of TNF superfamily ligands, BAFF AND APRIL, in the immune response of Atlantic salmon
    2018
  • Shiferaw Jenberie, Ma Michelle Demogina Penaranda, Morten Bay Styrvold, Hanna Leena Thim, Guro Strandskog, Linn G. Tollersrud m.fl.:
    PERITONEAL CAVITY B CELLS IN ATLANTIC SALMON (SALMO SALAR L.) – A CONTRIBUTOR TO THE LONG TERM HUMORAL IMMUNE RESPONSE AGAINST SALMONID ALPHAVIRUS (SAV)
    2018
  • Mahsa Jalili, Signe Løvmo Dille, Essa Ahsan Khan, Egil Lien, Jorunn B Jørgensen, Rolf Erik Olsen m.fl.:
    Activation of sterol regulatory element binding protein-1 and suppression of toll-like receptor-9 in Atlantic salmon by probiotic feeding
    2018
  • Ma Michelle Demogina Penaranda, Ingvill Jensen, Linn G. Tollersrud, Jack-Ansgar Bruun, Jorunn B Jørgensen :
    IDENTIFICATION AND GENE EXPRESSION ANALYSES OF POTENTIAL B CELL SURFACE MARKERS IN ATLANTIC SALMON
    2018
  • Ma Michelle Demogina Penaranda, Mikael Fjeld Wold, Shiferaw Jenberie, Ingvill Jensen, Jorunn B Jørgensen :
    A proliferation inducing ligand (APRIL) is a survival factor that plays an important role in the immune response of Atlantic salmon
    2018
  • Shiferaw Jenberie, Hanna Leena Thim, J Oriol Sunyer, Karsten Skjødt, Ingvill Jensen, Jorunn B Jørgensen :
    Author Correction: Profiling Atlantic salmon B cell populations: CpG-mediated TLR-ligation enhances IgM secretion and modulates immune gene expression
    Scientific Reports 2018 DOI
  • Jorunn B Jørgensen, Mehrdad Sobhkhez, Lisbeth Lindenskov Joensen, Guro Strandskog, Linn Greiner, Hanna Leena Thim :
    A role of SOCS1 in antiviral immunity?
    2016
  • Jorunn B Jørgensen :
    The TLR9 agonist CpG: A model to explore innate and adaptive immune responses in Atlantic salmon. A potential adjuvant for fish vaccines?
    2015
  • Dimitar Borisov Iliev, Guro Strandskog, Jorunn B Jørgensen :
    Exosomes released by Atlantic salmon (Salmo salar) leukocytes – composition and immunostimulatory properties
    2015
  • Guro Strandskog, Mehrdad Sobhkhez, Jorunn B Jørgensen, Dimitar Borisov Iliev :
    Composition of exosomes derived from Atlantic salmon (Salmo salar) head kidney leukocytes
    2015 ARKIV
  • Håvard Ingulfsvann Hagen, Ingvill Jensen, Jorunn B Jørgensen :
    Transkripsjonsfaktorer som markør for modning av B-celler i Atlantisk laks (Salmo salar L.) Effekt av TLR-ligander på utrykk av Pax5 in vitro og in vivo
    UiT Norges arktiske universitet 2014
  • Einar Ringø, Jorunn B Jørgensen, Ragnar Ludvig Olsen, Klara Stensvåg :
    Advances and prospects of biotechnology in aquaculture
    2013
  • Jorge Fernandes, Arvind Sundaram, V. Kiron, Jorunn B Jørgensen :
    Regulation of the innate immune response by microRNAs in zebrafish
    Fish and Shellfish Immunology 2013
  • Lill Heidi Johansen, Sven Martin Jørgensen, Hanna Leena Thim, Gerrit Timmerhaus, Sergey Afanasyev, Kjersti Kongsgården Fremmerlid m.fl.:
    Comparison of transcriptomic responses to pancreas disease (PD) and heart and skeletal muscle inflammation (HSMI) in Atlantic salmon (Salmo salar)
    Fish and Shellfish Immunology 2013

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    Forskningsinteresser

    Peer-reviewed Publications (from year 2003):

    1.  Iliev, D. B, Jørgensen, S; Rode, ; Krasnov, A;  Harneshaug, I. & J. B. Jørgensen (2009). CpG-induced secretion of MHCIIb from salmon (Salmo salar) APCs. Developmental & Comparative Immunology. Epub 19. August 2009.
    2. Skjaeveland, I., Iliev, D. B., Strandskog, G.& J. B. Jørgensen (2009). Identification and characterization of TLR8 and MyD88 homologs in Atlantic salmon (Salmo salar). Developmental & Comparative Immunology 2009. 33: 1011-1017.
    3. Skjæveland,I., D. B. Iliev, & J. B. Jørgensen(2009). Identification and characterization of TLR8 and MyD88 homologs in Atlantic salmon (Salmo salar.) Developmental & Comparative Immunology. 33: 1011-1017
    4. Skjesol, A,. Aamo, T,  M.N. Hegseth, Robertsen, B. & J.B. Jørgensen (2009). The interplay between infectious pancreatic necrosis virus (IPNV) and type I IFN. Inhibition of IFN signaling by IPNV proteins VP4 and VP5. Virus Research, 143, 53-60.
    5. Hansen,TE, Puntervoll,P, SeternesOM & J B. Jørgensen (2008). Atlantic salmon possess three mitogen activated protein kinase kinase 6 papralogs responding differently to stress. FEBS Journal, 275 4887-4902.  
    6. Strandskog, G., Skjæveland, I. Ellingsen & J. B. Jørgensen (2008).Double-stranded RNA and CpG DNA induced immune responses in Atlantic salmon: Comparison and synergies. Vaccine, 26, 4704-4715.
    7. Skjæveland,I., D. B. Iliev,J. Zou, T. Jørgensen & J. B. Jørgensen(2008).  A TLR9 homolog that is up-regulated by IFN- in Atlantic salmon (Salmon salar).Developmental and Comparative Immunology, 32, 603-607.
    8. Jørgensen, J. B, A. Johansen, M. N. Hegset, J. Zou,B. Robertsen, & C. J. Secombes (2007).  A recombinant CSHE-214 cell line expressing an Mx1 promoter-reporter system responds to both type I and II interferon from salmonids and represents a versatile tool to study the IFN-system in teleost fish. Fish & Shellfish Immunology, 23, 1294-1303.
    9. Røkenes,T. P., A. Skjesol & J.B. Jørgensen (2007). Intermolecular interactionsof infectious pancreas necrosis virus: capsid protein VP3 interacts with dsRNA and the RNA-dependent RNA polymerase VP1. Journal of Virology, 81, 6652-6663.
    10. Hansen, T. E. & J.B. Jørgensen (2007). Cloning and characterisation of p38 MAP kinase from Atlantic salmon. A kinase important for regulating salmon TNF-2 and IL-1β expression. Molecular Immunology, 44, 3137-3146.
    11. Strandskog, G. T. Ellingsen & J. B. Jørgensen (2007). Characterization of three distinct CpG oligonucleotide classes which differ in ability to induce IFNa/b activity and cell proliferation in Atlantic salmon (Salmo salar L.) leukocytes.Developmental and Comparative Immunology, 31, 39-51.
    12. Pedersen, G. M., Johansen, A., Olsen, R. L. & J. B. Jørgensen (2006). Stimulation of anti-viral mechanisms in Atlantic salmon (Salmo salar) leukocytes: synergetic effects of cationic proteins and CpG ODN. Fish and Shellfish Immunology, 20, 203-518.  
    13. Johansen, A., Collett, E. B., Sandaker, B;  Secombes, C. J.& Jørgensen, J. B. (2004). Quantification of Atlantic salmon type-I interferon using an Mx1 promoter reporter gene assay. Fish and Shellfish Immunology, 16,173-184.
    14. Jørgensen, J. B., L.-H. Johansen, K. Steiro & A. Johansen  (2003).  CpG DNA induces protective antiviral immune responses in Atlantic salmon (Salmo salar L.). Journal of Virology, 77, 11471-1147.    

    Invited speaker:

    2009:           

    Konferansen Frisk Fisk, Bergen, januar 2009: Stimulering av medfødt immunitet - en viktig strategi for nye generasjoner av vaksiner for fisk?                  

     Europharmas Lofoten-seminar, Lofoten juni 2009: Toll-lignende reseptorer: Ny mulighet for økt kontroll av virusinfeksjoner.   

    2006           

    10th International Congress of ISDCI, Charleston, South Carolina, USA. The use of CpG oligonucleotides as immunstimulants in fish. 

    2003           

     Funksjonell genomforskning i Norge: Til å leve av - til å leve med?  NRC, Fuge conference, Oslo, april 2003: Marin funksjonell genomforskning - hvordan sette Norge på verdenskartet? 

    2002           

    Bioteknologi i primærnæringene - visjon og nytte, Biotechnology program arranged conference at Continental Hotel NRC SAS Hotell, Gardemoen, september 2002: DNA er mer enn gener, spesielle DNA-sekvenser øker motstandsevnen mot sykdom hos laks.

    1999           

     Invited speaker at the workshop" Non-specific defence mechanisms of fish". EAFP 9th International Conference on Diseases of Fish and Shellfish, Rhodes, Greece: The potential use of DNA oligonucleotides as immunostimulants.

     

    Publikasjoner i Frida:

    https://www.cristin.no/as/WebObjects/cristin.woa/wa/fres?action=sok&etternavn=J%C3%B8rgensen&fornavn=Jorunn&ar-fra=2003&ar-til=2009&inst=186&erNorsk=1&erNordisk=1&erNasjonalt=1&erInternasjonalt=1&erUkjent=1&visParametre=1&bs=50


    Medlem i forskningsgruppe

    Fish Immunology and Vaccinology   English content

    Medlem i prosjekt

    FISH & CRISPR - Innovative strategies to improve salmon health ViVaAct: Comparing the protection of attenuated and inactivated virus vaccines against PD and HSMB Immune responses against Piscirickettsia salmonis in Atlantic salmon Multiple routes to B cell memory in Atlantic salmon Centre for Advanced Nanoscopy to Decode sub-cellular Biological Systems DNA Vaccine Development for Salmon viruses - Integrating innate and adaptive immunity - ImmunDNA