Ronny Helland
Arbeidsområder
Administrativ ledelse / Ansettelser / Arbeidsmiljø / Budsjett / Ekstern finansiering / Forskningsadministrasjon / Fravær / Helse, miljø og sikkerhet (HMS) / Lederstøtte / Lønn / Personaladministrasjon / Sidegjøremål / Sykmelding / Økonomi
Scott Mazurkewich,
Ronny Helland,
Alasdair Mackenzie,
Vincent Eijsink,
Phillip Byron Pope,
Gisela Brändén
m.fl.:
Structural insights of the enzymes from the chitin utilization locus of Flavobacterium johnsoniae
Bjarni Ásgeirsson,
Sigurbjörn Markússon,
Sigríður S. Hlynsdóttir,
Ronny Helland,
Jens G. Hjörleifsson
:
X-ray crystal structure of Vibrio alkaline phosphatase with the non-competitive inhibitor cyclohexylamine
Jens Guðmundur Hjörleifsson,
Ronny Helland,
Manuela Magnusdottir,
Bjarni Ásgeirsson
:
The high catalytic rate of the cold-active Vibrio alkaline phosphatase requires a hydrogen bonding network involving a large interface loop
Man Kumari Gurung,
Bjørn Altermark,
Ronny Helland,
Arne O. Smalås,
Inger Lin Uttakleiv Ræder
:
Features and structure of a cold active N-acetylneuraminate lyase
Ronny Helland,
Eva katrin Bjørkeng,
Ulli Rothweiler,
Magne Olav Sydnes,
Daniela Maria Pampanin
:
The crystal structure of haemoglobin from Atlantic cod
Concetta De Santi,
Osman A. B. S. M. Gani,
Ronny Helland,
Adele Kim Williamson
:
Structural insight into a CE15 esterase from the marine bacterial metagenome
Marit Seppola,
Kathrine Ryvold Bakkemo,
Helene V. Mikkelsen,
Bjørnar Myrnes,
Ronny Helland,
David Irwin
m.fl.:
Multiple specialised goose-type lysozymes potentially compensate for an exceptional lack of chickentype lysozymes in Atlantic cod
Hilde Lysvand,
Ronny Helland,
Lars Hagen,
Geir Slupphaug,
Ole-Jan Iversen
:
Psoriasis pathogenesis – Pso p27 constitutes a compact structure forming large aggregates
Tony Christopeit,
Trine Josefine Olsen Carlsen,
Ronny Helland,
Hanna-Kirsti S. Leiros
:
Discovery of novel inhibitor scaffolds against the metallo-β-lactamase VIM-2 by surface plasmon resonance (SPR) based fragment screening
Kenneth Johnson,
Thomas Ve,
Øivind Larsen,
Rolf B. Pedersen,
Johan R. Lillehaug,
Harald B Jensen
m.fl.:
CorA is a copper repressible surface-associated copper(I)-binding protein produced in Methylomicrobium album BG8
Zarah Forsberg,
Alasdair Mackenzie,
Morten Sørlie,
Åsmund Kjendseth Røhr,
Ronny Helland,
Andrew S. Arvai
m.fl.:
Structural and functional characterization of a conserved pair of bacterial cellulose-oxidizing lytic polysaccharide monooxygenases
Proceedings of the National Academy of Sciences of the United States of America (PNAS) 28. april 2014 DOI
D. Cazamea-Catalan,
E. Magnanou,
Ronny Helland,
L. Besseau,
Gilles Boeuf,
Jack Falcòn
m.fl.:
Unique arylalkylamine N-acetyltransferase-2 polymorphism in salmonids and profound variations in thermal stability and catalytic efficiency conferred by two residues
Journal of Experimental Biology 2013 DOI
Thomas Ve,
Karina Mathisen,
Ronny Helland,
Odd Andre Karlsen,
Anne Fjellbirkeland,
Åsmund Kjendseth Røhr
m.fl.:
The Methylococcus capsulatus (Bath) Secreted Protein, MopE*, Binds Both Reduced and Oxidized Copper
Leidy Lagos,
Dimitar Borisov Iliev,
Ronny Helland,
Mario Rosemblatt,
Jorunn B Jørgensen
:
CD40L-A costimulatory molecule involved in the maturation of antigen presenting cells in Atlantic salmon (Salmo salar)
Developmental and Comparative Immunology 2012 DOI
Damien D. Cazamèa-Catalan,
Elodie Magnanou,
Ronny Helland,
Gilmer Vanegas,
Laurence Besseau,
Gilles Boeuf
m.fl.:
Functional diversity of Teleost arylalkylamine N-acetyltransferase-2: is the timezyme evolution driven by habitat temperature?
Molecular Ecology 2012 DOI
Peter Kyomuhendo,
Bjørnar Myrnes,
Bjørn Olav Brandsdal,
Arne Smalås,
Inge Waller Nilsen,
Ronny Helland
:
Thermodynamics and structure of a salmon cold active goose-type lysozyme
Comparative Biochemistry and Physiology - Part B: Biochemistry & Molecular Biology 2010 DOI
Ronny Helland,
Renate Lie Larsen,
Solrun Finstad,
Peter Kyomuhendo,
Atle Noralf Larsen
:
Crystal structures of g-type lysozyme from Atlantic cod shed new light on substrate binding and the catalytic mechanism
Cellular and Molecular Life Sciences (CMLS) 2009 DOI
Anna Szlachcic,
M Zakrzewska,
D Krowarsch,
vibeke Os,
Ronny Helland,
Arne Oskar Smalås
m.fl.:
Structure of a highly stable mutant of human fibroblast growth factor 1
Acta Crystallographica Section D: Biological Crystallography 2009 DOI
Ronny Helland,
Renate Lie Larsen,
Bjarni Åsgeirsson
:
The 1.4 angstrom crystal structure of the large and cold-active Vibrio sp. alkaline phosphatase
Biochimica et Biophysica Acta - Proteins and Proteomics 2009 DOI
Bjørn Altermark,
Ronny Helland,
Elin Moe,
Nils Peder Willassen,
Arne Oskar Smalås
:
Structural adaptation of endonuclease I from the cold-adapted and halophilic bacterium Vibrio salmonicida
Acta Crystallographica Section D: Biological Crystallography 2008 DOI
Bjørn Altermark,
Ronny Helland,
Elin Moe,
Nils Peder Willassen,
Arne Oskar Smalås
:
Environmental adaptation of endonuclease I from Vibrio salmonicida
Acta Crystallographica Section D: Biological Crystallography 2008
Ronny Helland,
Anne Fjellbirkeland,
Odd-Arne Karlsen,
Johan Richard Lillehaug,
Harald Jensen,
Thomas Ve
:
An oxidized tryptophan facilitates copper binding in Methylococcus capsulatus-secreted protein MopE
Journal of Biological Chemistry 2008 DOI
Laila Mirja Niiranen,
Bjørn Altermark,
Bjørn Olav Brandsdal,
Hanna-Kirsti S. Leiros,
Ronny Helland,
Arne Oskar Smalås
m.fl.:
Effects of salt on the kinetics and thermodynamic stability of endonuclease I from Vibrio salmonicida and Vibrio cholerae
The FEBS Journal 2008 DOI
Ellen Kristin Riise,
marit sjo Lorentzen,
Ronny Helland,
Arne Oskar Smalås,
Hanna-Kirsti S. Leiros,
Nils Peder Willassen
:
The first structure of a cold-active catalase from Vibrio salmonicida at 1.96 angstrom reveals structural aspects of cold adaptation
Acta Crystallographica Section D: Biological Crystallography 2007 DOI
G Saelensminde,
Gisle Sælensminde,
O Halskau,
Øyvind Halskau,
Ronny Helland,
Nils Peder Willassen
m.fl.:
Structure-dependent relationships between growth temperature of prokaryotes and the amino acid frequency in their proteins
Extremophiles 2007 DOI
Ellen Kristin Riise,
Marit Sjo Lorentzen,
Ronny Helland,
Nils P Willassen
:
Crystallization and preliminary X-ray diffraction analysis of a cold-adapted catalase from Vibrio salmonicida
Acta Crystallographica. Section F : Structural Biology and Crystallization Communications 2006
Bjørn Altermark,
Arne Oskar Smalås,
Nils Peder Willassen,
Ronny Helland
:
The structure of Vibrio cholerae extracellular endonuclease I reveals the presence of a buried chloride ion
Acta Crystallographica Section D: Biological Crystallography 2006
Olayiwola Adekoya,
Ronny Helland,
Nils P Willassen,
Ingebrigt Sylte
:
Comparative sequence and structure analysis reveal features of cold adaptation of an enzyme in the thermolysin family
Proteins: Structure, Function, and Bioinformatics 2006
Ronny Helland,
Atle Noralf Larsen,
Arne Oskar Smalås,
Nils Peder Willassen
:
The 1.8 angstrom crystal structure of a proteinase K-like enzyme from a psychrotroph Serratia species
The FEBS Journal 2006
Atle Noralf Larsen,
Elin Moe,
Ronny Helland,
Dag Rune Gjellesvik,
Nils Peder Willassen
:
Characterization of a recombinantly expressed proteinase K-like enzyme from a psychrotrophic Serratia sp
The FEBS Journal 2006
Honorata Czapinska,
Ronny Helland,
Arne Oskar Smalås,
Jacek Otlewski
:
Crystal Structures of Five Bovine Chymotrypsin Complexes with P1 BPTI Variants
Journal of Molecular Biology (JMB) 2004
Hanna-Kirsti S. Leiros,
Hanna Kirsti Schrøder Leiros,
Bjørn Olav Brandsdal,
Ole Andreas Andersen,
vibeke Os,
Ingar Leiros
m.fl.:
Trypsin specificity as elucidated by LIE calculations, X-ray structures, and association constant measurements
Protein Science 2004
Man Kumari Gurung,
Tor Olav Berg,
Marie-Josée Haglund Halsør,
Bjørn Altermark,
Ingar Leiros,
Ronny Helland
m.fl.:
Efficient production of sialic acids- Using enzymes for biomass conversion
2017
Man Kumari Gurung,
Tor Olav Berg,
Marie-Josée Haglund Halsør,
Bjørn Altermark,
Ingar Leiros,
Ronny Helland
m.fl.:
Efficient production of sialic acids- Using enzymes for biomass conversion
2017
Tor Olav Berg,
Bjørn Altermark,
Ingar Leiros,
Ronny Helland,
Inger Lin Uttakleiv Ræder
:
Production of sialic acids and derivatives by enzyme catalysis
2016
Tor Olav Berg,
Marie-Josée Haglund Halsør,
Man Kumari Gurung,
Bjørn Altermark,
Ingar Leiros,
Ulli Rothweiler
m.fl.:
From marine rest raw materials to sialic acids: Using enzymes for biomass conversion
2016
Tor Olav Berg,
Bjørn Altermark,
Ingar Leiros,
Ronny Helland,
Inger Lin Uttakleiv Ræder
:
Biocatalytical production of sialic acids and derivatives
2015
Yvonne Piotrowski,
Netsanet Gizaw Assefa,
Ronny Helland,
Kirsti Merete Johannessen,
Nils Peder Willassen,
Atle Noralf Larsen
:
Enzymes from the Arctic - The cold gold
2015
Inger Lin Uttakleiv Ræder,
Bjørn Altermark,
Man Kumari Gurung,
Ronny Helland,
Arne O. Smalås
:
Sialic acids in marine bacteria
2014
Zarah Forsberg,
Alasdair Mackenzie,
Morten Sørlie,
Åsmund Kjendseth Røhr,
Ronny Helland,
Gustav Vaaje-Kolstad
m.fl.:
Characterization of cellulose-active lytic polysaccharide monooxygenases with complementary activities
2014
Yvonne Piotrowski,
Netsanet Gizaw Assefa,
Ronny Helland,
Kirsti Merete Johannessen,
Bjarne Landfald,
Arne O. Smalås
m.fl.:
Enzymes from the Arctic - The cold gold
2014
Inger Lin Uttakleiv Ræder,
Man Kumari Gurung,
Bjørn Altermark,
Tor Olav Berg,
Ronny Helland,
Arne O. Smalås
:
Sialic acid biosynthesis in marine bacteria
2013
Man Kumari Gurung,
Bjørn Altermark,
Inger Lin Uttakleiv Ræder,
Ronny Helland,
Arne O. Smalås
:
Features and structure of a sialic acid aldolase from Aliivibrio salmonicida
2013
Odd-Arne Olsen,
Wenche Johansen,
Sidsel Emilsen,
Tatiana Belova,
Zhe Liang,
Arne Smalås
m.fl.:
Structural & functional significance of the DEK1 phytocalpain during land plant evolution from green algae
2010
Atle Noralf Larsen,
Ronny Helland,
Gunbjørg Svineng,
Trond Ø. Jørgensen
:
Identification, cloning and recombinant expression of a goose-type lysozyme from Atlantic cod (Gadus Morhua)
2007
Bjørn Altermark,
Ronny Helland,
Laila Mirja Niiranen,
Elin Moe,
Bjørn Olav Brandsdal,
Arne Oskar Smalås
m.fl.:
Optimum enzymatic activity of endonuclease I from Vibrio salmonicida and Vibrio cholerae correlateswith the bacterial growth habitat
2006
Olayiwola Adedotun Adekoya,
Ronny Helland,
Nils Peder Willassen,
Ingebrigt Sylte
:
Structural determinants for a cold adapted enzyme in the thermolysin family
2005
Ronny Helland,
Atle Noralf Larsen,
Nils Peder Willassen
:
Structural basis for substrate specificity in two enzymes in the Proteinase K family
2005
Atle Noralf Larsen,
Ronny Helland,
Dag Rune Gjellesvik,
Nils Peder Willassen
:
Structural basis for S1-S4 specificity in two enzymes of the proteinase K family
2004
Pirkko a Heikinheimo,
Ronny Helland,
Hanna-Kirsti S. Leiros,
Ingar Leiros,
Solveig Karlsen,
gry Evjen
m.fl.:
Structure of the Bovine Lysosomal a-Mannosidase, the Enzyme Involved in the Lysosomal Storage Disease a-Mannosidosis
ESRF Highlights 2002 2003
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Forskningsinteresser
Mine forskningsinteresser inkluderer struktur-funksjonsstudier av proteiner (enzymer): Hvordan påvirker den atomære strukturen enzymers aktivitet, spesifisitet og effektivitet. Enzymer med opprinnelse i kuldetilpassede organismer har ofte helt unike biokjemiske egenskaper, og disse ønsker man kunne anvende i biokjemisk og bioteknologisk industri.
Deltakelse i prosjekter:
The Norwegian Structural Biology Centre
Bacterial sialic acids
MarSynth – Marine DNA modifying enzymes for synthetic biology
Optimization and Application Development of Marine Cold-adapted DNA Polymerases – OptiZyme