Roland Sauter,
Suraj Sharma,
Ines Heiland
:
Accounting for NAD Concentrations in Genome-Scale Metabolic Models Captures Important Metabolic Alterations in NAD-Depleted Systems
Anna-Sophia Egger,
Eva Rauch,
Suraj Sharma,
Tobias Kipura,
Madlen Hotze,
Thomas Mair
m.fl.:
Linking metabolism and histone acetylation dynamics by integrated metabolic flux analysis of Acetyl-CoA and histone acetylation sites
Lena Elise Høyland,
Magali R Van Linden,
Marc Niere,
Øyvind Strømland,
Suraj Sharma,
Jörn Lukas Franz Dietze
m.fl.:
Subcellular NAD+ pools are interconnected and buffered by mitochondrial NAD+
Nature Metabolism 2024
DOI
Suraj Sharma,
Yin-Chen Hsieh,
Jørn Dietze,
Mathias Bockwoldt,
Øyvind Strømland,
Mathias Ziegler
m.fl.:
Early Evolutionary Selection of NAD Biosynthesis Pathway in Bacteria
Jørn Dietze,
Alienke van Pijkeren,
Anna-Sophia Egger,
Mathias Ziegler,
Marcel Kwiatkowski,
Ines Heiland
:
Natural isotope correction improves analysis of protein modification dynamics
Analytical and Bioanalytical Chemistry 2021
DOI
Mathias Ziegler,
Magnus Monnè,
Andrey Nikiforov,
Gennaro Agrimi,
Ines Heiland,
Ferdinando Palmieri
:
Welcome to the Family: Identification of the NAD+ Transporter of Animal Mitochondria as Member of the Solute Carrier Family SLC25
Verena Panitz,
Saša Končarević,
Ahmed Sadik,
Dennis Friedel,
Tobias Bausbacher,
Saskia Trump
m.fl.:
Tryptophan metabolism is inversely regulated in the tumor and blood of patients with glioblastoma
Alienke Van Pijkeren,
Jørn Dietze,
Alejandro Sánchez Brotons,
Anna-Sophia Egger,
Tim Lijster,
Andrei Barcaru
m.fl.:
Combined metabolic and chemical (CoMetChem) labeling using stable isotopes - A strategy to reveal site-specific histone acetylation and deacetylation rates by LC-MS
Analytical Chemistry 2021
DOI
Soumya R Mohapatra,
Ahmed Sadik,
Suraj Sharma,
Gernot Poschet,
Hagen M Gegner,
Tobias V Lanz
m.fl.:
Hypoxia Routes Tryptophan Homeostasis Towards Increased Tryptamine Production
Mirja Tamara Prentzell,
Ulrike Rehbein,
Marti Cadena Sandoval,
Ann-Sofie De Meulemeester,
Ralf Baumeister,
Laura Brohée
m.fl.:
G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling
Mathias Bockwoldt,
Ines Heiland,
Karsten Fischer
:
The evolution of the plastid phosphate translocator family
Øyvind Strømland,
Marc Niere,
Andrey Nikiforov,
Magali R Van Linden,
Ines Heiland,
Mathias Ziegler
:
Keeping the balance in NAD metabolism
Biochemical Society Transactions 2019
ARKIV /
DOI
Mathias Bockwoldt,
Dorothee Houry,
Marc Niere,
Toni I. Gossmann,
Ines Reinartz,
Alexander Schug
m.fl.:
Identification of evolutionary and kinetic drivers of NAD-dependent signaling
Proceedings of the National Academy of Sciences of the United States of America (PNAS) 24. juli 2019
ARKIV /
DOI
Alexander Martin Heberle,
Patricia Razquin Navas,
Miriam Langelaar-Makkinje,
Katharina Kasack,
Ahmed Sadik,
Erik Faessler
m.fl.:
The PI3K and MAPK/p38 pathways control stress granule assembly in a hierarchical manner
Life Science Alliance (LSA) 2019
ARKIV /
DOI
Fabrizio Clarelli,
Jingyi Liang,
Antal Martinecz,
Ines Heiland,
Pia Abel zur Wiesch
:
Multi-scale modeling of drug binding kinetics to predict drug efficacy
Cellular and Molecular Life Sciences (CMLS) 2019
ARKIV /
DOI
Soumya R. Mohapatra,
Ahmed Sadik,
Lars-Oliver Tykocinski,
Jørn Dietze,
Gernot Poschet,
Ines Heiland
m.fl.:
Hypoxia Inducible Factor 1α Inhibits the Expression of Immunosuppressive Tryptophan-2,3-Dioxygenase in Glioblastoma
Frontiers in Immunology 2019
ARKIV /
DOI
Arina Afanasyeva,
Mathias Bockwoldt,
Christopher Cooney,
Ines Heiland,
Toni Ingolf Gossmann
:
Human long intrinsically disordered protein regions are frequent targets of positive selection
Isabell Adam,
Dyah L. Dewi,
Joram Mooiweer,
Ahmed Sadik,
Soumya R. Mohapatra,
Bianca Berdel
m.fl.:
Upregulation of tryptophanyl-tRNA synthethase adapts human cancer cells to nutritional stress caused by tryptophan degradation
Sascha Schäuble,
Anne-Kristin Stavrum,
Mathias Bockwoldt,
Pål Puntervoll,
Ines Heiland
:
SBMLmod: a Python-based web application and web service for efficient data integration and model simulation
Dyah L Dewi,
Soumya R Mohapatra,
Saioa Blanco Cabañes,
Isabell Adam,
Luis F Somarribas Patterson,
Bianca Berdel
m.fl.:
Suppression of indoleamine-2, 3-dioxygenase 1 expression by promoter hypermethylation in ER-positive breast cancer
Christiane A. Opitz,
Ines Heiland
:
Dynamics of NAD-metabolism: everything but constant
Biochemical Society Transactions 2015
DOI
Ines Heiland,
K Thedieck
:
Nutrigenomics: Toward a cross-disciplinary understanding of nutrient-driven networks in health and disease: What can we learn from the study of cross-talk in complex protein kinase and metabolic networks?
Aktuelle Ernãhrungsmedizin 2015
DOI
Walter Wencke,
Bernd Ketelsen,
Gaquerel Emmanuel,
Ian T. Baldwin,
Kim Sang-Gyu,
Ines Heiland
:
Improving the accuracy of expression data analysis in time course experiments using resampling
Anne-Kristin Stavrum,
Ines Heiland,
Stefan Schuster,
Pål Puntervoll,
Mathias Ziegler
:
Model of tryptophan metabolism, readily scalable using tissue-specific gene expression data
Journal of Biological Chemistry 2013
ARKIV /
DOI
Kathrin Schmeisser,
Johannes Mannsfeld,
Doreen Kuhlow,
Sandra Weimer,
Steffen Priebe,
Ines Heiland
m.fl.:
Role of sirtuins in lifespan regulation is linked to methylation of nicotinamide
Nature Chemical Biology 2013
DOI
Sascha Schäuble,
Anne-Kristin Stavrum,
Pål Puntervoll,
Stefan Schuster,
Ines Heiland
:
Effect of substrate competition in kinetic models of metabolic networks
Ines Heiland,
Christoph Kaleta
:
Stoffwechselanalyse: Neue Wege im Labyrinth entdecken
Laborwelt 2012
Ines Heiland
:
Kinetic regulation of NAD homeostasis
2022
Anze Zupanic,
Hans Christopher Bernstein,
Ines Heiland
:
Systems biology – Current status and challenges
Cellular and Molecular Biology 2020
ARKIV /
DOI
Mathias Bockwoldt,
Ines Heiland,
Toni Ingolf Gossmann,
Thomas Rattei
:
Sequence-Based Analysis of Eukaryotic Protein Evolution
UiT Norges arktiske universitet 2018
Toni Ingolf Gossmann,
Arina Afanasyeva,
Mathias Bockwoldt,
Ines Heiland,
Cooney Chris
:
Human intrinsically long disordered protein regions are frequent targets of positive selection
2017
Roland Sauter,
Ines Heiland
:
Arctic Marine Bioplastics
2017
Mathias Bockwoldt,
Ines Heiland,
Gossmann Toni,
Mathias Ziegler
:
Phylogenetic and simulation-based analysis of NAD metabolism
2016
Roland Sauter,
Ines Heiland
:
Metabolic Modeling of Marine Biomass Conversion
2016
Ines Heiland,
Mathias Bockwoldt,
Pål Puntervoll,
Sascha Schäuble,
Anne-Kristin Stavrum
:
Tissue specific models of Trp- and NAD-metabolism — insights into metabolic crosstalk.
2016
Mathias Bockwoldt,
Ines Heiland
:
Phylogenetic Analysis of NAD biosynthesis and consumption
2016
Ines Heiland,
Mathias Bockwoldt,
Anne-Kristin Stavrum,
Pål Puntervoll,
Mathias Ziegler
:
Tissue specific models of Tryptohan-metabolism — insights into metabolic crosstalk
2016
Mathias Bockwoldt,
Anne-Kristin Stavrum,
Toni I. Gossmann,
Mathias Ziegler,
Ines Heiland
:
Dynamics of NAD-metabolism - everything but constant
Carolyn Elliss,
Thomas Rattei,
Ines Heiland
:
50 Years of FEBS´ Education Training Awards
Mathias Bockwoldt,
Ines Heiland
:
Phylogenetic Analysis of NAD biosynthesis and consumption
2015
Mathias Bockwoldt,
Ines Heiland
:
Use of resampling to improve accuracy of data analysis in time course experiments
2015
Ines Heiland
:
Chemo Informatik: Was hat Tryptophan mit Krebs und Parkinson zu tun?
Chemie in unserer Zeit 2014
DOI
Wencke Walter,
Emmanuel Gaquerel,
Ian T. Baldwin,
Sang-Gyu Kim,
Ines Heiland
:
Improving the analysis of high throughput time course data using modelling based approaches
2014
Ines Heiland,
Susanne Brandes,
Anne-Kristin Stavrum,
Christian Bodenstein,
Mathias Ziegler
:
NAD-metabolism and the circadian clock -- Unraveling contradictions
2014
Anne-Kristin Stavrum,
Ines Heiland,
Stefan Schuster,
Pål Puntervoll,
Mathias Ziegler
:
Predicting pathological metabolic changes using a kinetic model of tryptophan metabolism
2014
Ines Heiland,
Susanne Brandes,
Anne-Kristin Stavrum,
Christian Bodenstein,
Mathias Ziegler
:
NAD-metabolism and the circadian clock
2013
Ines Heiland
:
Metabolic modelling: From networks to dynamics and back
2013
