Maria Therese Ahlen
Stillingsbeskrivelse
Forskning, undervisning og veiledning av studenter, Immunolgi.
Forsker ved Laboratoriemedisin og Nasjonal behandlingstjeneste for avanasert trombocyttimmunologi ved UNN www.unn.no/nnupi
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Forskningsinteresser
Blodplateimmunologi
T-cellereponser ved Føtal/neonatal alloimmun trombocytopeni
T celler i NAIT
(Foto: Elisabeth Øvreberg)
Publikasjoner
2018
High-resolution mapping of the polyclonal immune response to the human platelet alloantigen HPA-1a (PlA1). Blood Advances 2018; Nov 13;2(21):3001-3011. doi: 10.1182/bloodadvances.2018023341.
Orzińska A, Guz K, Uhrynowska M, Dȩbska M, Mikula M, Ostrowski J, Ahlen MT, Husebekk A, Brojer E.Noninvasive prenatal HPA-1 typing in HPA-1a negative pregnancies selected in the Polish PREVFNAIT screening program. Transfusion 2018 s. 1-7
2017
Dahl, J, Refsum E, Ahlen MT, Egeland T, Jensen T, Viken MK, Stuge TB, Acharya G, Husebekk A, Skogen B, Tiller H. Unraveling the role of maternal anti-HLA class I antibodies in fetal and neonatal thrombocytopenia?Antibody specificity analysis using epitope data. Journal of Reproductive Immunology 2017 ;Volum 122. s. 1-
Tiller H, Husebekk A, Ahlen, MT, Stuge, TB, Skogen, B. Current perspectives on fetal and neonatal alloimmune thrombocytopenia - Increasing clinical concerns and new treatment opportunities. International Journal of Women's Health 2017 ;Volum 9. s. 223-234
2016
Ahlen MT, Husebekk A, Killie IL, Skogen B, Stuge, TB. T cell responses to human platelet antigen-1a involve a unique form of indirect allorecognition. JCI Insight 2016 ;Volum Sep 8.(1) Suppl. 14 s. e86558
2013
Heide G, Stuge TB, Skogen B, Husebekk A, Ahlen MT. The DR7-DQ2 haplotype in a native Norwegian population. Scand J Immunol. 2013 May;77(5):429-30
2012
Husebekk A, El Ekiaby M, Gorgy G, Killie MK, Uhlin-Hansen C, Salma W, Navarrete C, El Afandi M, Skogen B, Ahlen MT. Foetal/neonatal alloimmune thrombocytopenia in Egypt; human platelet antigen genotype frequencies and antibody detection and follow-up in pregnancies. Transfus Apher Sci. 2012 May 26.
Ahlen MT, Husebekk A, Killie MK, Kjeldsen-Kragh J, Olsson ML and Skogen B. The development of severe neonatal alloimmune thrombocytopenia due to anti-HPA-1a antibodies is correlated to maternal ABO genotypes. Clin Dev Immunol. 2012:156867.
2011
Stuge TB, Skogen B, Ahlen MT, Husebekk A, Urbaniak SJ, Bessos H. The cellular immunobiology associated with fetal and neonatal alloimmune thrombocytopenia. Transfus Apher Sci. 2011 Aug;45(1):53-9. Review.
2010
Husebekk A, Ahlen MT; Killie MK, Tiller H, Eksteen M, Killie IL, Heide G, Kjeldsen-Kragh J, Skogen BR, Stuge TB. Blood group antigens and immune responses-detailed knowledge is necessary to prevent immunization and to follow up immunized individuals. ISBT Science Series 2010 ;Volum 5.(1) s. 24-26
Skogen BR, Killie MK, Kjeldsen-Kragh J, Ahlen MT, Tiller H, StugeTB, Husebekk A. Reconsidering fetal and neonatal alloimmune thrombocytopenia with a focus on screening and prevention. Expert Review of Hematology 2010 ;Volum 3.(5) s. 559-566
2009
Ahlen MT, Husebekk A, Killie MK, Skogen BR, Stuge TB. T-cell responses associated with neonatal alloimmune thrombocytopenia: isolation of HPA-1a-specific, HLA-DRB3*0101-restricted CD4+ T cells. Blood 2009 ;Volum 113.(16) s. 3838-3844