Schneider, Yannik Karl Heinz
Researcher
Stillingsbeskrivelse
Reseach Interests:
My interest is to discover new bioactive molecules for drug discovery, mainly from marine bacteria. A crucial step in the discovery-process is the identification of known or unknown molecules which is heavily relying on HPLC-HR-MS2. Beside anti-cancer and other pharmaceutically relevant bioactivities, anti-bacterial activity and MoA is a strong interest of mine. Identified candidates are then isolated and their structure is elucidated by NMR. Another project I am working on deals with the screenig of marine rest-raw-material hydrolysates for new neutraceuticals to combat the metabolic syndrome.
At a glance:
HPLC/ Liquid-Chromatography
Analytical and preparative Chemistry
Mass Spectrometry/ HR-MS/MS and Ion mobillity spectroscopy (IMS), Metabolomics
NMR
Natural product drug discovery (anti-cancer, anti-bacterial, anti-inflammatory...)
Investigation of Compounds Molecular Mode of Action
Bioactive Peptides/ Neutraceuticals from Marine Rest-Raw-Material
- Schneider, Yannik Karl-Heinz; Jørgensen, Solveig; Andersen, Jeanette Hammer; Hansen, Espen. Qualitative and quantitative comparison of liquid–liquid phase extraction using ethyl acetate and liquid–solid phase extraction using poly-benzyl-resin for natural products. Applied Sciences 2021; Volum 11 (21). ISSN 2076-3417.s doi: 10.3390/app112110241.
- Schneider, Yannik Karl-Heinz. Bacterial Natural Product Drug Discovery for New Antibiotics: Strategies for Tackling the Problem of Antibiotic Resistance by Efficient Bioprospecting. Antibiotics 2021; Volum 10 (7). ISSN 2079-6382.s doi: 10.3390/antibiotics10070842.
- Schneider, Yannik Karl-Heinz; Jenssen, Marte; Isaksson, Johan; Østnes Hansen, Kine; Andersen, Jeanette Hammer; Hansen, Espen. Bioactivity of Serratiochelin A, a Siderophore Isolated from a Co-Culture of Serratia sp. and Shewanella sp.. Microorganisms 2020; Volum 8 (7). ISSN 2076-2607.s 1 - 17.s doi: 10.3390/microorganisms8071042.
- Schneider, Yannik Karl-Heinz; Østnes Hansen, Kine; Isaksson, Johan; Ullsten-Wahlund, Sara Maria; Hansen, Espen; Andersen, Jeanette Hammer. Anti-Bacterial Effect and Cytotoxicity Assessment of Lipid 430 Isolated from Algibacter sp.. Molecules 2019; Volum 24 (21). ISSN 1420-3049.s doi: 10.3390/molecules24213991.
Forskningsinteresser
Reseach Interests:
My interest is to discover new bioactive molecules for drug discovery, mainly from marine bacteria. A crucial step in the discovery-process is the identification of known or unknown molecules which is heavily relying on HPLC-HR-MS2. Beside anti-cancer and other pharmaceutically relevant bioactivities, anti-bacterial activity and MoA is a strong interest of mine. Identified candidates are then isolated and their structure is elucidated by NMR. Another project I am working on delas with the screenig of marine rest-raw-material hydrolysates for new neutraceuticals to combat the metabolic syndrome.
At a glance:
HPLC/ Liquid-Chromatography
Analytical and preparative Chemistry
Mass Spectrometry/ HR-MS and Ion mobillity spectroscopy (IMS), Metabolomics
NMR
Natural product druch discovery (anti-cancer, anti-bacterial, anti-inflammatory...)
Investigation of Compounds Molecular Mode of Action
Bioactive Peptides/ Neutraceuticals from Marine Rest-Raw-Material
Undervisning
BIO-2606: Forlesning: Restråstoff fra fiskeindustrien og makroalger, prosessering og applikasjoner
FSK-1122: Mikrobiologie og Biokjemi: Forelesning og Seminar i Mikrobiologi
