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  3. Yannik Karl Heinz Schneider
Bilde av Schneider, Yannik Karl Heinz
Bilde av Schneider, Yannik Karl Heinz
Norges fiskerihøgskole yannik.k.schneider@uit.no +4777649267 Tromsø FPARK A 280

Schneider, Yannik Karl Heinz

Researcher

Stillingsbeskrivelse

Reseach Interests:

My  interest is to discover new bioactive molecules for drug discovery, mainly from marine bacteria. A crucial step in the discovery-process is the identification of known or unknown molecules which is heavily relying on HPLC-HR-MS2. Beside anti-cancer and other pharmaceutically relevant bioactivities, anti-bacterial activity and MoA is a strong interest of mine. Identified candidates are then isolated and their structure is elucidated by NMR. Another project I am working on deals with the screenig of marine rest-raw-material hydrolysates for new neutraceuticals to combat the metabolic syndrome.

At a glance:

HPLC/ Liquid-Chromatography

Analytical and preparative Chemistry

Mass Spectrometry/ HR-MS/MS and Ion mobillity spectroscopy (IMS), Metabolomics

NMR

Natural product drug discovery (anti-cancer, anti-bacterial, anti-inflammatory...)

Investigation of Compounds Molecular Mode of Action

Bioactive Peptides/ Neutraceuticals from Marine Rest-Raw-Material

  • Fazlin Pheiffer, Yannik Karl Heinz Schneider, Espen Holst Hansen, Jeanette Hammer Andersen, Johan Mattias Isaksson, Tobias Busche m.fl.:
    Bioassay-Guided Fractionation Leads to the Detection of Cholic Acid Generated by the Rare Thalassomonas sp.
    Marine Drugs 2022 ARKIV / DOI
  • Sara Ullsten-Wahlund, Guillaume Petit, Johan Mattias Isaksson, Ida Kristine Østnes Hansen, Yannik Karl Heinz Schneider, Marte Jenssen m.fl.:
    Identification of New Purpuroine Analogues from the Arctic Echinodermata Pteraster militaris That Inhibit FLT3-ITD+ AML Cell Lines
    International Journal of Molecular Sciences 2022 ARKIV / DOI
  • Yannik Karl Heinz Schneider, Ole Christian Hagestad, Chun Li, Espen Holst Hansen, Jeanette Hammer Andersen :
    Selective isolation of Arctic marine actinobacteria and a down-scaled fermentation and extraction strategy for identifying bioactive compounds
    Frontiers in Microbiology 21. oktober 2022 ARKIV / DOI
  • Yannik Karl-Heinz Schneider, Solveig Jørgensen, Jeanette Hammer Andersen, Espen Hansen :
    Qualitative and quantitative comparison of liquid–liquid phase extraction using ethyl acetate and liquid–solid phase extraction using poly-benzyl-resin for natural products
    Applied Sciences 2021 ARKIV / DOI
  • Yannik Karl-Heinz Schneider :
    Bacterial Natural Product Drug Discovery for New Antibiotics: Strategies for Tackling the Problem of Antibiotic Resistance by Efficient Bioprospecting
    Antibiotics 2021 ARKIV / DOI
  • Yannik Karl-Heinz Schneider, Marte Jenssen, Johan Isaksson, Kine Østnes Hansen, Jeanette Hammer Andersen, Espen Hansen :
    Bioactivity of Serratiochelin A, a Siderophore Isolated from a Co-Culture of Serratia sp. and Shewanella sp.
    Microorganisms 14. juli 2020 ARKIV / DOI
  • Yannik Karl-Heinz Schneider, Kine Østnes Hansen, Johan Isaksson, Sara Maria Ullsten-Wahlund, Espen Hansen, Jeanette Hammer Andersen :
    Anti-Bacterial Effect and Cytotoxicity Assessment of Lipid 430 Isolated from Algibacter sp.
    Molecules 2019 ARKIV / DOI
  • Yannik Karl Heinz Schneider :
    ReSTRAIN - Strain selection for efficient bioprospecting. Which traits indicate the biosynthetic potential of bacterial strains?
    2022
  • Yannik Karl-Heinz Schneider, Njål Rauø, Espen Holst Hansen, Jeanette Hammer Andersen, Jascha MacDonald, Wolfgang R. Streit m.fl.:
    The SuReMetS-project - From sustainable resources to novel marine nutraceuticals for the management of metabolic syndrome
    2021
  • Yannik Karl-Heinz Schneider, Espen Hansen :
    Quantitative comparison of solid and liquid phase extraction of natural products from bacterial fermentations
    2019

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    Forskningsinteresser

    Reseach Interests:

    My  interest is to discover new bioactive molecules for drug discovery, mainly from marine bacteria. A crucial step in the discovery-process is the identification of known or unknown molecules which is heavily relying on HPLC-HR-MS2. Beside anti-cancer and other pharmaceutically relevant bioactivities, anti-bacterial activity and MoA is a strong interest of mine. Identified candidates are then isolated and their structure is elucidated by NMR. Another project I am working on delas with the screenig of marine rest-raw-material hydrolysates for new neutraceuticals to combat the metabolic syndrome.

    At a glance:

    HPLC/ Liquid-Chromatography

    Analytical and preparative Chemistry

    Mass Spectrometry/ HR-MS and Ion mobillity spectroscopy (IMS), Metabolomics

    NMR

    Natural product druch discovery (anti-cancer, anti-bacterial, anti-inflammatory...)

    Investigation of Compounds Molecular Mode of Action

    Bioactive Peptides/ Neutraceuticals from Marine Rest-Raw-Material

    Undervisning

    BIO-2606: Forlesning: Restråstoff fra fiskeindustrien og makroalger, prosessering og applikasjoner

    FSK-1122: Mikrobiologie og Biokjemi: Forelesning og Seminar i Mikrobiologi

    Forskerprofil i Cristin
    ResearchGate

    Medlem i forskningsgruppe

    Marbio – an analytical platform for natural products   Norsk innhold