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Bilde av Obuobi, Sybil Akua Okyerewa
Bilde av Obuobi, Sybil Akua Okyerewa
Institutt for farmasi sybil.obuobi@uit.no Her finner du meg

Sybil Akua Okyerewa Obuobi

Forsker

  • Alexandra Sofia Antunes de Sousa, Vegard Borøy, Agnethe Hansen Bæverud, Kjersti Julin, Annette Bayer, Morten B. Strøm m.fl.:
    Polymyxin B stabilized DNA micelles for sustained antibacterial and antibiofilm activity against P. aeruginosa
    Journal of materials chemistry. B 2023 DOI
  • Alexandra Sofia Antunes De Sousa, Anna Ngoc Phung, Natasa Skalko-Basnet, Sybil Akua Okyerewa Obuobi :
    Smart delivery systems for microbial biofilm therapy: Dissecting design, drug release and toxicological features
    Journal of Controlled Release 2023 ARKIV / DOI
  • Sybil Akua Okyerewa Obuobi, Anna Ngoc Phung, Kjersti Julin, Mona Johannessen, Natasa Skalko-Basnet :
    Biofilm Responsive Zwitterionic Antimicrobial Nanoparticles to Treat Cutaneous Infection
    Biomacromolecules 2021 ARKIV / DOI
  • Viveka Kalidasan, Xin Yang, Ze Xiong, Renee R. Li, Haicheng Yao, Hareesh Godaba m.fl.:
    Wirelessly operated bioelectronic sutures for the monitoring of deep surgical wounds
    Nature Biomedical Engineering 2021 ARKIV / DOI
  • Sybil Akua Okyerewa Obuobi, Venkatesh Mayandi, Azlyn Mohd Nor Nurul, Benedict Jiasheng Lee, Rajamani Lakshminarayanan, Rachel Ee Pui Lai :
    Nucleic acid peptide nanogels for the treatment of bacterial keratitis
    Nanoscale 2020 ARKIV / DOI
  • Sybil Akua Okyerewa Obuobi, Kjersti Julin, Elizabeth G. Aarag Fredheim, Mona Johannessen, Natasa Skalko-Basnet :
    Liposomal delivery of antibiotic loaded nucleic acid nanogels with enhanced drug loading and synergistic anti-inflammatory activity against S. aureus intracellular infections
    Journal of Controlled Release 2020 ARKIV / DOI
  • Sybil Akua Okyerewa Obuobi, Natasa Skalko-Basnet :
    Nucleic acid hybrids as advanced antibacterial nanocarriers
    Pharmaceutics 2020 ARKIV / DOI
  • Vanitha Selvarajan, Sybil Akua Okyerewa Obuobi, Rachel Ee Pui Lai :
    Silica Nanoparticles—A Versatile Tool for the Treatment of Bacterial Infections
    Frontiers in Chemistry 2020 ARKIV / DOI
  • Jian Yao Ng, Sybil Akua Okyerewa Obuobi, Mei Ling Chua, Chi Zhang, Shiqi Hong, Yogesh Kumar m.fl.:
    Biomimicry of microbial polysaccharide hydrogels for tissue engineering and regenerative medicine - A review
    Carbohydrate Polymers 2020 ARKIV / DOI
  • Alexandra Sofia Antunes de Sousa, Kjersti Julin, Annette Bayer, Morten Bøhmer Strøm, Mona Johannessen, Natasa Skalko-Basnet m.fl.:
    Drug-loaded DNA nanoparticles against bioflms
    2023
  • Sybil Akua Okyerewa Obuobi :
    Advancing drug delivery via nanocarrier design to treat biofilm infections
    2023
  • Sybil Akua Okyerewa Obuobi :
    Advancing drug delivery via DNA nanocarrier design to treat persistent infections
    2023
  • Kjersti Julin, Annette Bayer, Morten Bøhmer Strøm, Mona Johannessen, Natasa Skalko-Basnet, Sybil Akua Okyerewa Obuobi :
    DNA Nanocarriers for improved biofilm penetration
    2022
  • Sybil Akua Okyerewa Obuobi :
    Hybrid DNA nanoparticles for the treatment of persistent S. aureus infections
    2022
  • Sybil Akua Okyerewa Obuobi :
    The day that Sigurd the Viking died from a bacterial infection
    2022
  • Sybil Akua Okyerewa Obuobi :
    Dagen da Sigurd Viking døde av en bakterieinfeksjon
    2022
  • Sybil Akua Okyerewa Obuobi :
    A personal journey beyond failure: My funding story
    2022
  • Sybil Akua Okyerewa Obuobi :
    BIOHYBRID NUCLEIC ACID CARRIERS FOR THE TREATMENT OF PERSISTENT INFECTIONS
    2022
  • Sybil Akua Okyerewa Obuobi :
    Biohybrid Nucleic Acid carriers for the treatment of persistent infections
    2022
  • Sybil Akua Okyerewa Obuobi :
    Vikingen Sigurd døde da tennene til en død mann skrapte borti leggen hans
    28. juli 2022
  • Sybil Akua Okyerewa Obuobi :
    Nanocarriers are the Trojan horses of anti­biotics
    UiT Forskerhjørnet 2022 FULLTEKST
  • Sybil Akua Okyerewa Obuobi :
    Nanocarriers are the Trojan horses of anti­biotics
    sciencenorway.no 2022 FULLTEKST
  • Sybil Akua Okyerewa Obuobi :
    Fat bubbles and DNA help sneak antibiotics into biofilms
    09. mai 2022
  • Sybil Akua Okyerewa Obuobi :
    High drug loading hybrid carriers for antimicrobial applications
    2022
  • Sybil Akua Okyerewa Obuobi, Anna Ngoc Phung, Kjersti Julin, Mona Johannessen, Natasa Skalko-Basnet :
    Zwitterionic Nanohybrids for the Treatment of Wound Biofilms
    2021
  • Sybil Akua Okyerewa Obuobi, Anna Ngoc Phung, Kjersti Julin, Mona Johannessen, Natasa Skalko-Basnet :
    Zwitterionic hybrid nanoparticles for the treatment of biofilm wound infections
    2021
  • Sybil Akua Okyerewa Obuobi, Anna Ngoc Phung, Kjersti Julin, Mona Johannessen, Natasa Skalko-Basnet :
    Multi-responsive and Zwitterionic Nanohybrids for the Treatment of Biofilm Wound Infections
    2021
  • Sybil Akua Okyerewa Obuobi, Anna Ngoc Phung, Kjersti Julin, Mona Johannessen, Natasa Skalko-Basnet :
    ZWITTERIONIC NUCLEIC ACID HYBRIDS FOR THE TREATMENT OF BIOFILM INFECTIONS
    2021
  • Sybil Akua Okyerewa Obuobi, Anna Ngoc Phung, Kjersti Julin, Mona Johannessen, Natasa Skalko-Basnet :
    Multi-responsive and Zwitterionic Nanohybrids for the Treatment of Biofilm Wound Infections
    2021
  • Sybil Akua Okyerewa Obuobi, Kjersti Julin, Elizabeth G. Aarag Fredheim, Mona Johannessen, Natasa Skalko-Basnet :
    Liposomal delivery of Nucleic Acid Nanogels to Enhance Entrapment Efficiency and Sustain Release of Antibiotics against Staphylococcal intracellular infections
    2020
  • Sybil Akua Okyerewa Obuobi, Kjersti Julin, Elizabeth G. Aarag Fredheim, Pål Jarle Johnsen, Mona Johannessen, Natasa Skalko-Basnet :
    Liposomal delivery of antibiotic loaded DNA nanogels against intracellular infections
    2020

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    Forskningsinteresser

    My research is focused on the development of innovative antimicrobial drug delivery systems and the in-depth elucidation of their transport routes and efficacy in vivo . I am particularly interested in adapting biopolymeric nanocarriers and their hybrids for the treatment of intracellular and topical infections. I have particular interest in DNA nanostructures and protein-based nanocarriers as multifunctional platforms for infectious disease therapy. Using conventional antibiotics and antimicrobial peptides, my past and recent research seeks to provide alternative formulations to address the growing threat of multidrug resistant pathogens.I have other experiences developing these polymers into hydrogels or nanogels and liposomes for wound healing applications.  

    Forskerprofil i Cristin
    ResearchGate
    ORCID: https://orcid.org/0000-0002-2905-581X

    Medlem i forskningsgruppe

    Drug Transport and Delivery   English content

    Medlem i prosjekt

    Bacteria responsive and intrinsically active antimIcrobial nanohybrids    English content

    CV

     

    EDUCATION

    13/01/2014 - 31/05/2018. Department of Pharmacy, National University of Singapore (NUS), Singapore (PhD)

    22/09/2012 -17/09/2013. Aston University, United Kingdom (MSc Drug Delivery)

    08/2006 - 06/2010. Kwame Nkrumah University of Science & Technology, Ghana (BSc. Pharmacy)

    CURRENT AND PREVIOUS POSITIONS

    05/2019 - present Marie Curie Postdoctoral Researcher, UIT, Norway.                                                                     

    02/11/2017 - 31/01/2018 Research Fellow, Max Plank Institute for Polymer Research (MPIP), Germany.

    FUNDING / Scholarship

    05/2019 to present Marie Curie Individual Fellowship, UIT, The Arctic University of Norway, Tromsø, Norway

    01/11/2017 - 30/01/2018 Otto Bayer Fellowship, Max Planck Institute for Polymer Research, Mainz, Germany

    13/01/2014 - 13/01/2018 Singapore International Graduate Award, National University of Singapore, Singapore

    19/09/2012 - 17/09/2013 Commonwealth Scholarship, Aston University, United Kingdom

    PRIZES / AWARDS
    02/2019 Marie Curie Individual Fellowship, UIT, The Arctic University of Norway, Tromsø, Norway

    19/06/2018 GPEN 2018 Abstract Award, Department of Pharmacy, NUS, Singapore.

    26/09/2017 Otto Bayer Fellowship, Max Planck Institute for Polymer Research, Mainz, Germany.

    21/06/2017 Best Graduate Researcher Award, Faculty of Science, Department of Pharmacy, NUS, Singapore.

    05/04/2017 Best Postgraduate Research Project, Department of Pharmacy, NUS, Singapore.

    2004 Academic Excellence Award, Akosombo International School, Ghana.