Bilde av Fredheim, Elizabeth G Aarag
Bilde av Fredheim, Elizabeth G Aarag
Institutt for farmasi elizabeth.aarag@uit.no +4777646652

Elizabeth G Aarag Fredheim


Førsteamanuensis


  • Hymonti Dey, Danijela Simonovic, Ingrid Sofie Norberg-Schulz Hagen, Terje Vasskog, Elizabeth G. Aarag Fredheim, Hans-Matti Blencke m.fl.:
    Synthesis and Antimicrobial Activity of Short Analogues of the Marine Antimicrobial Peptide Turgencin A: Effects of SAR Optimizations, Cys-Cys Cyclization and Lipopeptide Modifications
    International Journal of Molecular Sciences 2022 ARKIV / DOI
  • Jonina Gudmundsdottir, Elizabeth G. Aarag Fredheim, Catharina I.M. Koumans, Joachim Hegstad, Po-Cheng Tang, Dan I. Andersson m.fl.:
    The chemotherapeutic drug methotrexate selects for antibiotic resistance
    EBioMedicine 2021 ARKIV / DOI
  • Sybil Akua Okyerewa Obuobi, Kjersti Julin, Elizabeth G. Aarag Fredheim, Mona Johannessen, Natasa Skalko-Basnet :
    Liposomal delivery of antibiotic loaded nucleic acid nanogels with enhanced drug loading and synergistic anti-inflammatory activity against S. aureus intracellular infections
    Journal of Controlled Release 2020 ARKIV / DOI
  • João Alves Gama, Elizabeth G. Aarag Fredheim, Francois Pierre Alexandre Cléon, Ana Maria Reis, Rita Zilhão, Francisco Dionisio :
    Dominance between plasmids determines the extent of biofilm formation
    Frontiers in Microbiology 2020 ARKIV / DOI
  • Runa Wolden, Maria Pain, Roger Karlsson, Anders Karlsson, Elizabeth G. Aarag Fredheim, Jorunn Pauline Cavanagh :
    Identification of surface proteins in a clinical Staphylococcus haemolyticus isolate by bacterial surface shaving
    BMC Microbiology 2020 ARKIV / DOI
  • Hildegunn Norbakken Granslo, Elizabeth Aarag, Eirin Esaiassen, Lars Christophersen, Peter Østrup Jensen, Tom Eirik Mollnes m.fl.:
    The synthetic antimicrobial peptide LTX21 induces inflammatory responses in a human whole blood model and a murine peritoneum model
    APMIS - Journal of Pathologiy, Microbiology and Immunology 2019 ARKIV / DOI
  • Nicole L. Podnecky, Elizabeth Aarag, Julia Maria Kloos, Vidar Sørum, Raul Primicerio, Adam Paul Roberts m.fl.:
    Conserved collateral antibiotic susceptibility networks in diverse clinical strains of Escherichia coli.
    Nature Communications 10. september 2018 ARKIV / DOI
  • Elizaveta Igumnova, Ekaterina Mishchenko, Tor Haug, Hans-Matti Blencke, Johanna U Ericson Sollid, Elizabeth Aarag m.fl.:
    Amphipathic sulfonamidobenzamides mimicking small antimicrobial marine natural products; investigation of antibacterial and anti-biofilm activity against antibiotic resistant clinical isolates.
    Bioorganic & Medicinal Chemistry 2018 DOI
  • Elizaveta Mikhailovna Igumnova, Ekaterina Mishchenko, Tor Haug, Hans-Matti Blencke, Johanna U Ericson Sollid, Elizabeth Aarag m.fl.:
    Synthesis and antimicrobial activity of small cationic amphipathic aminobenzamide marine natural product mimics and evaluation of relevance against clinical isolates including ESBL–CARBA producing multi-resistant bacteria
    Bioorganic & Medicinal Chemistry 2016 DOI
  • Caio Fernando de Oliveira, Jorunn Pauline Cavanagh, Elizabeth Aarag, Keli Cristine Reiter, Alexandre Rieger, Claus Klingenberg m.fl.:
    Coagulase-negative staphylococci in southern brazil: Looking toward its high diversity
    Revista da Sociedade Brasileira de Medicina Tropical 2016 ARKIV / DOI
  • Jorunn Pauline Cavanagh, Runa Wolden, Philipp Heise, Eirin Esaiassen, Claus Klingenberg, Elizabeth Aarag :
    Antimicrobial susceptibility and body site distribution of community isolates of coagulase-negative staphylococci
    APMIS - Journal of Pathologiy, Microbiology and Immunology 2016 ARKIV / DOI
  • Elizaveta Mikhailovna Igumnova, Ekaterina Mishchenko, Tor Haug, Hans-Matti Blencke, Johanna U Ericson Sollid, Elizabeth G Aarag Fredheim m.fl.:
    Synthesis and antimicrobial activity of small cationic amphipathic aminobenzamide marine natural product mimics and evaluation of relevance against clinical isolates including ESBL–CARBA producing multi-resistant bacteria.
    Bioorganic & Medicinal Chemistry 2016 DOI
  • Elizabeth Aarag, Trond Flægstad, Fatemeh Askarian, Claus Klingenberg :
    Colonisation and interaction between S. epidermidis and S. aureus in the nose and throat of healthy adolescents.
    European Journal of Clinical Microbiology and Infectious Diseases 2015 DOI
  • Elizabeth Aarag Fredheim, Trond Flægstad, Fatemeh Askarian, Claus Klingenberg :
    Colonisation and interaction between S. epidermidis and S. aureus in the nose and throat of healthy adolescents
    European Journal of Clinical Microbiology and Infectious Diseases 2014 DOI
  • Jorunn Pauline Cavanagh, Hildegunn Norbakken Granslo, Elizabeth Aarag, L Christophersen, Peter Østrup Jensen, Kim Thomsen m.fl.:
    Efficacy of a synthetic antimicrobial peptidomimetic versus vancomycin in a Staphylococcus epidermidis device-related murine peritonitis model
    Journal of Antimicrobial Chemotherapy 2013 DOI
  • Hildegunn Norbakken Granslo, Claus Klingenberg, Elizabeth A. Fredheim, Ganesh Acharya, Tom Eirik Mollnes, Trond Flægstad :
    Staphylococcus epidermidis biofilms induce lower complement activation in neonates as compared with adults
    Pediatric Research 2013 DOI
  • Jorunn Pauline Cavanagh, Claus Klingenberg, Anne-Merethe Hanssen, Elizabeth Aarag, Patrice Francois, Jaques Schrenzel m.fl.:
    Core genome conservation of Staphylococcus haemolyticus limits sequence based population structure analysis
    Journal of Microbiological Methods 2012 ARKIV / DOI
  • Elizabeth Aarag, Hildegunn Norbakken Granslo, Trond Flægstad, Yngve Figenschau, H Rohde, I Sadovskaya m.fl.:
    Staphylococcus epidermidis polysaccharide intercellular adhesin activates complement
    FEMS Immunology and Medical Microbiology 2011 DOI
  • Hildegunn Norbakken Granslo, Claus Klingenberg, Elizabeth Aarag, Arild Erlend Rønnestad, Tom Eirik Mollnes, Trond Flægstad :
    Arginine Catabolic Mobile Element Is Associated With Low Antibiotic Resistance and Low Pathogenicity in Staphylococcus epidermidis From Neonates
    Pediatric Research 2010 DOI
  • Elizabeth Aarag, Claus Klingenberg, Holger Rohde, S Frankenberger, Petter Gaustad, T Flaegstad m.fl.:
    Biofilm Formation by Staphylococcus haemolyticus
    Journal of Clinical Microbiology 2009 DOI
  • Karianne Wiger Gammelsrud, Elizabeth Aarag, Trond Flaegstad, Claus Klingenberg, Hildegunn Thorsteinsen Granslo :
    Biofilm og antibiotikaresistens hos koagulasenegative stafylokokker
    Tidsskrift for Den norske legeforening 2008
  • Hildegunn Norbakken Granslo, K W Gammelsrud, Elizabeth Aarag, Trond Flaegstad, Claus Klingenberg :
    Koagulase negative stafylokokker - biofilm og antibiotikaresistens
    Tidsskrift for Den norske legeforening 2008
  • Hymonti Dey, Danijela Simonovic, Ingrid Sofie Norberg-Schulz Hagen, Terje Vasskog, Elizabeth G. Aarag Fredheim, Hans-Matti Blencke m.fl.:
    Antimicrobial activity and mode of action study of short cyclic analogues of the marine antimicrobial peptide Turgencin A
    2023
  • Miriam Kristine Karlsen, Anna Kaarina Pöntinen, Rebecca Ashley Gladstone, Joao Pedro Alves Gama, Elizabeth Gladys Aarag Fredheim :
    Biofilm-associated traits of human pathogenic Escherichia coli
    2023
  • Miriam Kristine Karlsen, Anna Kaarina Pöntinen, João Alves Gama, Rebecca Ashley Gladstone, Vidar Sørum, Elizabeth G. Aarag Fredheim :
    Disclosing the biofilmome of Escherichia coli
    2022
  • Miriam Kristine Karlsen, Anna Kaarina Pöntinen, João Alves Gama, Rebecca Ashley Gladstone, Vidar Sørum, Elizabeth G. Aarag Fredheim :
    Disclosing the biofilmome of Escherichia coli
    2022
  • Miriam Kristine Karlsen, Anna Kaarina Pöntinen, João Alves Gama, Rebecca Ashley Gladstone, Vidar Sørum, Elizabeth G. Aarag Fredheim :
    Disclosing the biofilmome of Escherichia coli
    2022
  • Hymonti Dey, Danijela Simonovic, Ingrid Sofie Norberg-Schulz Hagen, Terje Vasskog, Elizabeth G. Aarag Fredheim, Hans-Matti Blencke m.fl.:
    Antimicrobial Activity and Mode of Action Study of Short Analogues of The Marine Antimicrobial Peptide Turgencin A
    2022
  • Danijela Simonovic, Hymonti Dey, Natascha Johansen, Trude Anderssen, Terje Vasskog, Elizabeth G. Aarag Fredheim m.fl.:
    Investigation of the antimicrobial activity and proteolytic stability of the short analogues of the marine peptide EeCentrocin 1
    2022
  • Pål Jarle Johnsen, Elizabeth G Aarag Fredheim, Ørjan Samuelsen, Klaus Harms :
    The role of drugs used in cancer chemotherapy as drivers of antibiotic resistance evolution in Escherichia coli
    2022
  • Hymonti Dey, Danijela Simonovic, Ingrid Sofie Norberg-Schulz Hagen, Terje Vasskog, Elizabeth G. Aarag Fredheim, Hans-Matti Blencke m.fl.:
    Antimicrobial activity and mode of action study of short analogues of the marine antimicrobial peptide Turgencin A
    2021
  • Danijela Simonovic, Hymonti Dey, Natascha Johansen, Trude Anderssen, Terje Vasskog, Elizabeth G. Aarag Fredheim m.fl.:
    Investigation of the antimicrobial activity and proteolytic stability of the short analogues of the marine peptide EeCentrocin 1
    2021
  • Sybil Akua Okyerewa Obuobi, Kjersti Julin, Elizabeth G. Aarag Fredheim, Mona Johannessen, Natasa Skalko-Basnet :
    Liposomal delivery of Nucleic Acid Nanogels to Enhance Entrapment Efficiency and Sustain Release of Antibiotics against Staphylococcal intracellular infections
    2020
  • Sybil Akua Okyerewa Obuobi, Kjersti Julin, Elizabeth G. Aarag Fredheim, Pål Jarle Johnsen, Mona Johannessen, Natasa Skalko-Basnet :
    Liposomal delivery of antibiotic loaded DNA nanogels against intracellular infections
    2020
  • Runa Wolden, Maria Pain, Roger Karlsson, Anders Karlsson, Elizabeth G. Aarag Fredheim, Jorunn Pauline Cavanagh :
    Hunting new targets to prevent infections - A novel approach to bacterial surface shaving
    2019
  • Runa Wolden, Maria Pain, Roger Karlsson, Anders Karlsson, Elizabeth G. Aarag Fredheim, Jorunn Pauline Cavanagh :
    På jakt etter nye målsete for behandling av Staphylococcus haemolyticus-infeksjonar: Opp- regulering av sentrale virulens- og adhesjonsprotein hos S. haemolyticus ved kolonisering av humane keratinocyttar
    2019
  • Elizabeth G. Aarag Fredheim, Jonina Gudmundsdottir :
    Stand på forskningstorg under Utforsk UiT, Forskningsdagene 2019
    2019
  • Elizabeth G. Aarag Fredheim, Nicole Podnecky, Angie Carola Alarcon Rios, Jessica Nguyen Tran, Chantal Verstappen, Klaus Harms m.fl.:
    Gentamicin collateral sensitivity of ciprofloxacin resistant Escherichia coli is opposed by the rapid development of gentamicin resistance
    2019
  • Sören Abel, Anel Mahmutovic, Aaron Nicholas Gillman, Aime Manzi, Natasha-Anne Robson Moe, Silje Lauksund m.fl.:
    How to blast a biofilm
    2018
  • Ekaterina Mishchenko, Elizaveta Igumnova, Johanna U Ericson Sollid, Hans-Matti Blencke, Reidunn Silje Lauksund, Tor Haug m.fl.:
    Antibacterial marine natural product mimics for treatment of infections.
    2017
  • Hildegunn Norbakken Granslo, Elizabeth Aarag, Claus Andreas Klingenberg, Claus Moser, Eirin Esaiassen, Jorunn Pauline Cavanagh m.fl.:
    The synthetic antimicrobial peptide LTX21 induces inflammatory responses in an in vivo mouse peritonitis model and an ex vivo human whole blood model
    2017
  • Ekaterina Mishchenko, Johanna U Ericson Sollid, Hans-Matti Blencke, Tor Haug, Elizabeth Aarag, Klara Stensvåg :
    Antibacterial and Anti-biofilm Activity of Novel Marine Natural Product Mimics
    UiT Norges arktiske universitet 2017
  • Ekaterina Mishchenko, Elizaveta Igumnova, Hans-Matti Blencke, Johanna U Ericson Sollid, Elizabeth Aarag, Tor Haug m.fl.:
    Antibacterial studies of compounds inspired by marine natural products
    2016
  • Ekaterina Mishchenko, Elizaveta Igumnova, Hans-Matti Blencke, Elizabeth Aarag, Johanna U Ericson Sollid, Tor Haug m.fl.:
    Antimicrobial studies of Marine Natural Product Mimics (MNPMs)
    2015
  • Ekaterina Mishchenko, Elizaveta Igumnova, Hans-Matti Blencke, Elizabeth Aarag, Johanna U Ericson Sollid, Tor Haug m.fl.:
    In vitro studies of the activities of marine natural product mimics on Stapylococcus epidermidis biofilms
    2014
  • Ekaterina Mishchenko, Elizaveta Mikhailovna Igumnova, Johanna U Ericson Sollid, Elizabeth Aarag, Hans-Matti Blencke, Tor Haug m.fl.:
    Antimicrobial and anti-biofilm studies of Marine Natural Product Mimics
    2014
  • Ekaterina Mishchenko, Elizaveta Igumnova, Hans-Matti Blencke, Johanna U. Ericson Sollid, Elizabeth Aarag, Tor Haug m.fl.:
    Antibacterial and anti-biofilm studies of synthetic compounds derived from marine antimicrobial compounds
    2013
  • Ekaterina Mishchenko, Elizaveta Igumnova, Elizabeth Aarag, Johanna U. Ericson Sollid, Tor Haug, Hans-Matti Blencke m.fl.:
    Antimicrobial and anti-biofilm activities of novel synthetic compounds based on marine bioactive molecules
    2013
  • Ekaterina Mishchenko, Elizaveta Igumnova, Elizabeth Aarag, Johanna U. Ericson Sollid, Hans-Matti Blencke, Tor Haug m.fl.:
    Antibacterial and anti-biofilm activity studies of synthetic compounds inspired by natural bioactive compounds
    2013
  • Ekaterina Mishchenko, Elizaveta Igumnova, Johanna U. Ericson Sollid, Elizabeth Aarag, Hans-Matti Blencke, Tor Haug m.fl.:
    Antimicrobial biofilm studies of synthetic compounds inspired by marine natural compounds
    2013

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    Forskningsinteresser

    Infeksjon

    Biofilm

    Immunologi

    Bioprospektering

     

    Undervisning

    Immunologi og Mikrobiologi FAR-2201