Bilde av Blencke, Hans-Matti
Foto:
Bilde av Blencke, Hans-Matti
Norges fiskerihøgskole hans-matti.blencke@uit.no +4777644474 +4791827294 Tromsø NFH C 372

Hans-Matti Blencke


Førsteamanuensis/ mikrobiologi, bioprospektering, bioteknologi

Stillingsbeskrivelse

mikrobiologi

Vitenskapelige arbeidsområder


  • Manuel K Langer, Ataur Rahman, Hymonti Dey, Trude Anderssen, Francesco Zilioli, Tor Haug m.fl.:
    A concise SAR-analysis of antimicrobial cationic amphipathic barbiturates for an improved activity-toxicity profile
    European Journal of Medicinal Chemistry 2022 ARKIV / FULLTEKST / DATA / DOI
  • Hymonti Dey, Danijela Simonovic, Ingrid Sofie Norberg-Schulz Hagen, Terje Vasskog, Elizabeth G. Aarag Fredheim, Hans-Matti Blencke m.fl.:
    Synthesis and Antimicrobial Activity of Short Analogues of the Marine Antimicrobial Peptide Turgencin A: Effects of SAR Optimizations, Cys-Cys Cyclization and Lipopeptide Modifications
    International Journal of Molecular Sciences 2022 ARKIV / DOI
  • Marianne Hagensen Paulsen, Magnus Engqvist, Dominik Ausbacher, Trude Anderssen, Manuel K- Langer, Tor Haug m.fl.:
    Amphipathic Barbiturates as Mimics of Antimicrobial Peptides and the Marine Natural Products Eusynstyelamides with Activity against Multi-resistant Clinical Isolates
    Journal of Medicinal Chemistry 2021 ARKIV / DOI
  • Ida Kristine Østnes Hansen, Johan Isaksson, Aaron G. Poth, Kine Østnes Hansen, Aaron John Christian Andersen, Céline Sarah Marine Richard m.fl.:
    Isolation and characterization of antimicrobial peptides with unusual disulfide connectivity from the colonial ascidian Synoicum turgens
    Marine Drugs 2020 ARKIV / DOI
  • Rui Han, Hans-Matti Blencke, Hao Cheng, Chun Li :
    The antimicrobial effect of CEN1HC-Br against Propionibacterium acnes and its therapeutic and anti-inflammatory effects on acne vulgaris
    Peptides 2018 ARKIV / DOI
  • Elizaveta Igumnova, Ekaterina Mishchenko, Tor Haug, Hans-Matti Blencke, Johanna U Ericson Sollid, Elizabeth Aarag m.fl.:
    Amphipathic sulfonamidobenzamides mimicking small antimicrobial marine natural products; investigation of antibacterial and anti-biofilm activity against antibiotic resistant clinical isolates.
    Bioorganic & Medicinal Chemistry 2018 DOI
  • Elizaveta Mikhailovna Igumnova, Ekaterina Mishchenko, Tor Haug, Hans-Matti Blencke, Johanna U Ericson Sollid, Elizabeth Aarag m.fl.:
    Synthesis and antimicrobial activity of small cationic amphipathic aminobenzamide marine natural product mimics and evaluation of relevance against clinical isolates including ESBL–CARBA producing multi-resistant bacteria
    Bioorganic & Medicinal Chemistry 2016 DOI
  • Elizaveta Mikhailovna Igumnova, Ekaterina Mishchenko, Tor Haug, Hans-Matti Blencke, Johanna U Ericson Sollid, Elizabeth G Aarag Fredheim m.fl.:
    Synthesis and antimicrobial activity of small cationic amphipathic aminobenzamide marine natural product mimics and evaluation of relevance against clinical isolates including ESBL–CARBA producing multi-resistant bacteria.
    Bioorganic & Medicinal Chemistry 2016 DOI
  • Victoria Paulsen, Mario Mardirossian, Hans-Matti Blencke, Monica Benincasa, Giulia Runti, Matteo Nepa m.fl.:
    Inner membrane proteins YgdD and SbmA are required for the complete susceptibility of Escherichia coli to the proline rich antimicrobial peptide arasin 1(1–25)
    Microbiology (Reading) 2016 DOI
  • Chun Li, Hans-Matti Blencke, Tor Haug, Klara Stensvåg :
    Antimicrobial peptides in echinoderm host defense
    Developmental and Comparative Immunology 2015 ARKIV / DOI
  • Chun Li, Hans-Matti Blencke, Tor Haug, Øyvind Jørgensen, Klara Stensvåg :
    Expression of antimicrobial peptides in coelomocytes and embryos of the green sea urchin (Strongylocentrotus droebachiensis)
    Developmental and Comparative Immunology 2014 ARKIV / DOI
  • Victoria Paulsen, Hans-Matti Blencke, Monica Benincasa, Tor Haug, Jacobus Johannes Eksteen, Olaf B. Styrvold m.fl.:
    Structure-activity relationships of the antimicrobial peptide arasin 1 - and mode of action studies of the N terminal, proline-rich region
    PLOS ONE 2013 FULLTEKST / ARKIV / DOI
  • Juan Fu, Hanna-Kirsti S. Leiros, Donatella De pascale, Kenneth Johnson, Hans-Matti Blencke, Bjarne Landfald :
    Functional and structural studies of a novel cold-adapted esterase from an Arctic intertidal metagenomic library
    Applied Microbiology and Biotechnology 2013 DOI
  • Camilla Bjørn, Joakim Håkansson, Emma Myhrman, Veronika Sjøstrand, Tor Haug, Kerstin Lindgren m.fl.:
    Anti-infectious and anti-inflammatory effects of peptide fragments sequentially derived from the antimicrobial peptide centrocin 1 isolated from the green sea urchin, Strongylocentrotus droebachiensis
    AMB Express 13. desember 2012 DATA / ARKIV / DOI
  • Ida Kristine Østnes Hansen, Tor Haug, Klara Stensvåg, Hans-Matti Blencke :
    Antimicrobial peptides from the Arctic ascidian Synoicum turgens
    2022
  • Hymonti Dey, Danijela Simonovic, Ingrid Sofie Norberg-Schulz Hagen, Terje Vasskog, Elizabeth G. Aarag Fredheim, Hans-Matti Blencke m.fl.:
    Antimicrobial Activity and Mode of Action Study of Short Analogues of The Marine Antimicrobial Peptide Turgencin A
    2022
  • Hymonti Dey, Danijela Simonovic, Ingrid Sofie Norberg-Schulz Hagen, Terje Vasskog, Elizabeth G. Aarag Fredheim, Hans-Matti Blencke m.fl.:
    Antimicrobial activity and mode of action study of short analogues of the marine antimicrobial peptide Turgencin A
    2021
  • Sebastian Reidar Barriteau Siiri, Tor Haug, Klara Stensvåg, Hans-Matti Blencke :
    Antimikrobielle forbindelser i sjøstjernen Asterias rubens og sjøpølsen Cucumaria frondosa
    2019
  • Klara Stensvåg, Jonathan Hira, Ekaterina Mishchenko, Hans-Matti Blencke, Morten B. Strøm, Bjarne Landfald m.fl.:
    Marine antimicrobial peptides – an inspiration for new compounds to fight bacteria
    2019
  • Ekaterina Mishchenko, Eric Juskewitz, Hans-Matti Blencke, Deanna Wolfson, Johanna U Ericson Sollid :
    Antibacterial activity of novel marine-derived ”middle-space” molecules: mode of action studies
    2018
  • Klara Stensvåg, Tor Haug, Runar Gjerp Solstad, Ekaterina Mishchenko, Chun Li, Hans-Matti Blencke :
    Bioactive compounds from marine resources
    2017
  • Klara Stensvåg, Tor Haug, Ekaterina Mishchenko, Hans-Matti Blencke :
    Marine natural resources – examples of health beneficial active components
    2017
  • Ekaterina Mishchenko, Hans-Matti Blencke, Tor Haug, Klara Stensvåg :
    Bioactive compounds from marine organisms in the High North - future antibiotics?
    2017
  • Ekaterina Mishchenko, Elizaveta Igumnova, Johanna U Ericson Sollid, Hans-Matti Blencke, Reidunn Silje Lauksund, Tor Haug m.fl.:
    Antibacterial marine natural product mimics for treatment of infections.
    2017
  • Klara Stensvåg, Tor Haug, Ekaterina Mishchenko, Hans-Matti Blencke :
    Marine antimicrobial compounds and their potential as lead compounds for novel antibiotics
    2017
  • Ekaterina Mishchenko, Johanna U Ericson Sollid, Hans-Matti Blencke, Tor Haug, Elizabeth Aarag, Klara Stensvåg :
    Antibacterial and Anti-biofilm Activity of Novel Marine Natural Product Mimics
    2017
  • Ida Kristine Hansen, Kine Ø. Hanssen, Hans-Matti Blencke, Klara Stensvåg, Tor Haug :
    Antimicrobial peptides from Arctic ascidians
    2017
  • Ekaterina Mishchenko, Elizaveta Igumnova, Hans-Matti Blencke, Johanna U Ericson Sollid, Elizabeth Aarag, Tor Haug m.fl.:
    Antibacterial studies of compounds inspired by marine natural products
    2016
  • Runar Gjerp Solstad, Hans-Matti Blencke, Ekaterina Mishchenko, Chun Li, Inger Rødum, Tor Haug m.fl.:
    Bioactive peptides from marine sources
    2016
  • Inger Kristine Rødum, Chun Li, Hans-Matti Blencke, Klara Stensvåg, Tor Haug :
    Antimicrobial peptides in the marine horse mussel, Modiolus modiolus
    2015 DATA
  • Ekaterina Mishchenko, Elizaveta Igumnova, Hans-Matti Blencke, Elizabeth Aarag, Johanna U Ericson Sollid, Tor Haug m.fl.:
    Antimicrobial studies of Marine Natural Product Mimics (MNPMs)
    2015
  • Runar Gjerp Solstad, Hans-Matti Blencke, Yaroslav Alekseevich Andreev, Magne Olav Sydnes, Morten Kaare Moe, Steinar Daae Johansen m.fl.:
    Bioactive peptides of Arctic marine invertebrates
    2015
  • Chun Li, Hans-Matti Blencke, Tor Haug, Klara Stensvåg :
    Fishing an immune receptor by microorganism affinity matrix
    2015
  • Hans-Matti Blencke, Chun Li, Tor Haug, Klara Stensvåg :
    Centrocin, an important contributor to green sea urchin self defense?
    2015 DATA
  • Klara Stensvåg, Hans-Matti Blencke, Yaroslav Alekseevich Andreev, Runar Gjerp Solstad, Chun Li, Magne Olav Sydnes m.fl.:
    Exploring the bioactive peptide space of arctic marine invertebrates
    2014
  • Ekaterina Mishchenko, Elizaveta Igumnova, Hans-Matti Blencke, Elizabeth Aarag, Johanna U Ericson Sollid, Tor Haug m.fl.:
    In vitro studies of the activities of marine natural product mimics on Stapylococcus epidermidis biofilms
    2014
  • Ekaterina Mishchenko, Elizaveta Mikhailovna Igumnova, Johanna U Ericson Sollid, Elizabeth Aarag, Hans-Matti Blencke, Tor Haug m.fl.:
    Antimicrobial and anti-biofilm studies of Marine Natural Product Mimics
    2014
  • Magnus Støback Bjørsvik, Klara Stensvåg, Hans-Matti Blencke :
    Design av en transkripsjonssensor i Escherichia coli : til deteksjon av virkningsmåten til nyoppdagede antimikrobielle peptider
    2013
  • Ekaterina Mishchenko, Elizaveta Igumnova, Hans-Matti Blencke, Johanna U. Ericson Sollid, Elizabeth Aarag, Tor Haug m.fl.:
    Antibacterial and anti-biofilm studies of synthetic compounds derived from marine antimicrobial compounds
    2013
  • Ekaterina Mishchenko, Elizaveta Igumnova, Elizabeth Aarag, Johanna U. Ericson Sollid, Tor Haug, Hans-Matti Blencke m.fl.:
    Antimicrobial and anti-biofilm activities of novel synthetic compounds based on marine bioactive molecules
    2013
  • Runar Gjerp Solstad, Hans-Matti Blencke, Yaroslav A. Andreev, Magne Olav Sydnes, Morten Kaare Moe, Steinar Daae Johansen m.fl.:
    Exploring the bioactive peptide space of arctic marine invertebrates
    2013
  • Ekaterina Mishchenko, Elizaveta Igumnova, Elizabeth Aarag, Johanna U. Ericson Sollid, Hans-Matti Blencke, Tor Haug m.fl.:
    Antibacterial and anti-biofilm activity studies of synthetic compounds inspired by natural bioactive compounds
    2013
  • Ekaterina Mishchenko, Elizaveta Igumnova, Johanna U. Ericson Sollid, Elizabeth Aarag, Hans-Matti Blencke, Tor Haug m.fl.:
    Antimicrobial biofilm studies of synthetic compounds inspired by marine natural compounds
    2013
  • Victoria Paulsen, Klara Stensvåg, Hans-Matti Blencke, Tor Haug :
    The proline-arginine-rich antimicrobial peptide arasin 1 from the marine spider crab, Hyas araneus. Active derivatives - and mechanisms of action studies
    2013
  • Chun Li, Tor Haug, Hans-Matti Blencke, Klara Stensvåg :
    Antimicrobial peptides in the green sea urchin Strongylocentrotus droebachiensis
    2012
  • Tor Haug, Hans-Matti Blencke, Sigmund Sperstad, Chun Li, Victoria Paulsen, Margey Tadesse m.fl.:
    Antibiotics from the sea – a MabCent project
    2012
  • sigmund Sperstad, Tor Haug, Victoria Paulsen, Hans-Matti Blencke, Olaf B. Styrvold, Klara Stensvåg :
    Diversity of antimicrobial peptides from the spider crab, Hyas araneus
    2011
  • Klara Stensvåg, Chun Li, Tor Haug, Hans-Matti Blencke, Olaf B. Styrvold :
    Characteristics and potential use of antimicrobial peptides from sea urchin, Strongylocentrotus droebachiensis
    2011
  • Juan Fu, Hans-Matti Blencke, Donatella De pascale, Bjarne Landfald :
    A novel cold-adapted esterase from an arctic intertidal metagenomic library
    2011
  • Margey Tadesse, Tor Haug, Hans-Matti Blencke, Marcel Jaspars, Klara Stensvåg :
    Antimicrobial compounds from the Sea
    2011

  • De 50 siste resultatene fra Cristin vises på siden. Se alle arbeider i Cristin her →

    Publikasjoner utenom Cristin




    Forskningsinteresser

    I am interested in determining the mechanisms of action of novel antimicrobial compounds, therefore I try to develop easy to use and reliable assays for an initial characterization. I am also interested in developing specific assays for pinpointing molecular interactions of antimicrobial compounds with their target molecules inside bacteria.

    Undervisning

    FSK-2005, Bio-1601


    Medlem i forskningsgruppe