Hans-Matti Blencke
Førsteamanuensis/ mikrobiologi, bioprospektering, bioteknologi
Stillingsbeskrivelse
mikrobiologi
Vitenskapelige arbeidsområder
Manuel K Langer,
Ataur Rahman,
Hymonti Dey,
Trude Anderssen,
Hans-Matti Blencke,
Tor Haug
m.fl.:
Investigation of Tetrasubstituted Heterocycles Reveals Hydantoins as a Promising Scaffold for Development of Novel Antimicrobials with Membranolytic Properties
European Journal of Medicinal Chemistry 2023
Hymonti Dey,
Danijela Simonovic,
Ingrid Sofie Norberg-Schulz Hagen,
Terje Vasskog,
Elizabeth G. Aarag Fredheim,
Hans-Matti Blencke
m.fl.:
Synthesis and Antimicrobial Activity of Short Analogues of the Marine Antimicrobial Peptide Turgencin A: Effects of SAR Optimizations, Cys-Cys Cyclization and Lipopeptide Modifications
Manuel K Langer,
Ataur Rahman,
Hymonti Dey,
Trude Anderssen,
Francesco Zilioli,
Tor Haug
m.fl.:
A concise SAR-analysis of antimicrobial cationic amphipathic barbiturates for an improved activity-toxicity profile
Marianne Hagensen Paulsen,
Magnus Engqvist,
Dominik Ausbacher,
Trude Anderssen,
Manuel K- Langer,
Tor Haug
m.fl.:
Amphipathic Barbiturates as Mimics of Antimicrobial Peptides and the Marine Natural Products Eusynstyelamides with Activity against Multi-resistant Clinical Isolates
Ida Kristine Østnes Hansen,
Johan Isaksson,
Aaron G. Poth,
Kine Østnes Hansen,
Aaron John Christian Andersen,
Céline Sarah Marine Richard
m.fl.:
Isolation and characterization of antimicrobial peptides with unusual disulfide connectivity from the colonial ascidian Synoicum turgens
Rui Han,
Hans-Matti Blencke,
Hao Cheng,
Chun Li
:
The antimicrobial effect of CEN1HC-Br against Propionibacterium acnes and its therapeutic and anti-inflammatory effects on acne vulgaris
Elizaveta Igumnova,
Ekaterina Mishchenko,
Tor Haug,
Hans-Matti Blencke,
Johanna U Ericson Sollid,
Elizabeth Aarag
m.fl.:
Amphipathic sulfonamidobenzamides mimicking small antimicrobial marine natural products; investigation of antibacterial and anti-biofilm activity against antibiotic resistant clinical isolates.
Bioorganic & Medicinal Chemistry 2018 DOI
Elizaveta Mikhailovna Igumnova,
Ekaterina Mishchenko,
Tor Haug,
Hans-Matti Blencke,
Johanna U Ericson Sollid,
Elizabeth Aarag
m.fl.:
Synthesis and antimicrobial activity of small cationic amphipathic aminobenzamide marine natural product mimics and evaluation of relevance against clinical isolates including ESBL–CARBA producing multi-resistant bacteria
Bioorganic & Medicinal Chemistry 2016 DOI
Elizaveta Mikhailovna Igumnova,
Ekaterina Mishchenko,
Tor Haug,
Hans-Matti Blencke,
Johanna U Ericson Sollid,
Elizabeth G Aarag Fredheim
m.fl.:
Synthesis and antimicrobial activity of small cationic amphipathic aminobenzamide marine natural product mimics and evaluation of relevance against clinical isolates including ESBL–CARBA producing multi-resistant bacteria.
Bioorganic & Medicinal Chemistry 2016 DOI
Victoria Paulsen,
Mario Mardirossian,
Hans-Matti Blencke,
Monica Benincasa,
Giulia Runti,
Matteo Nepa
m.fl.:
Inner membrane proteins YgdD and SbmA are required for the complete susceptibility of Escherichia coli to the proline rich antimicrobial peptide arasin 1(1–25)
Microbiology (Reading) 2016 DOI
Chun Li,
Hans-Matti Blencke,
Tor Haug,
Klara Stensvåg
:
Antimicrobial peptides in echinoderm host defense
Chun Li,
Hans-Matti Blencke,
Tor Haug,
Øyvind Jørgensen,
Klara Stensvåg
:
Expression of antimicrobial peptides in coelomocytes and embryos of the green sea urchin (Strongylocentrotus droebachiensis)
Victoria Paulsen,
Hans-Matti Blencke,
Monica Benincasa,
Tor Haug,
Jacobus Johannes Eksteen,
Olaf B. Styrvold
m.fl.:
Structure-activity relationships of the antimicrobial peptide arasin 1 - and mode of action studies of the N terminal, proline-rich region
Juan Fu,
Hanna-Kirsti S. Leiros,
Donatella De pascale,
Kenneth Johnson,
Hans-Matti Blencke,
Bjarne Landfald
:
Functional and structural studies of a novel cold-adapted esterase from an Arctic intertidal metagenomic library
Applied Microbiology and Biotechnology 2013 DOI
Camilla Bjørn,
Joakim Håkansson,
Emma Myhrman,
Veronika Sjøstrand,
Tor Haug,
Kerstin Lindgren
m.fl.:
Anti-infectious and anti-inflammatory effects of peptide fragments sequentially derived from the antimicrobial peptide centrocin 1 isolated from the green sea urchin, Strongylocentrotus droebachiensis
Ida Kristine Østnes Hansen,
Tor Haug,
Klara Stensvåg,
Hans-Matti Blencke
:
Antimicrobial peptides from the Arctic ascidian Synoicum turgens
2022
Hymonti Dey,
Danijela Simonovic,
Ingrid Sofie Norberg-Schulz Hagen,
Terje Vasskog,
Elizabeth G. Aarag Fredheim,
Hans-Matti Blencke
m.fl.:
Antimicrobial Activity and Mode of Action Study of Short
Analogues of The Marine Antimicrobial Peptide Turgencin A
2022
Ataur Rahman,
Andrea Iselin Elvheim,
Christoffer Ågnes,
Ida Kristine Østnes Hansen,
Bjarne Landfald,
Hans-Matti Blencke
m.fl.:
Antimicrobial and antibiofilm potential of marine bacteria
2022
Hymonti Dey,
Danijela Simonovic,
Ingrid Sofie Norberg-Schulz Hagen,
Terje Vasskog,
Elizabeth G. Aarag Fredheim,
Hans-Matti Blencke
m.fl.:
Antimicrobial activity and mode of action study of short analogues of the marine antimicrobial peptide Turgencin A
2021
Sebastian Reidar Barriteau Siiri,
Tor Haug,
Klara Stensvåg,
Hans-Matti Blencke
:
Antimikrobielle forbindelser i sjøstjernen Asterias rubens og sjøpølsen Cucumaria frondosa
2019
Klara Stensvåg,
Jonathan Hira,
Ekaterina Mishchenko,
Hans-Matti Blencke,
Morten B. Strøm,
Bjarne Landfald
m.fl.:
Marine antimicrobial peptides – an inspiration for new compounds to fight bacteria
2019
Ekaterina Mishchenko,
Eric Juskewitz,
Hans-Matti Blencke,
Deanna Wolfson,
Johanna U Ericson Sollid
:
Antibacterial activity of novel marine-derived
”middle-space” molecules: mode of action studies
2018
Klara Stensvåg,
Tor Haug,
Runar Gjerp Solstad,
Ekaterina Mishchenko,
Chun Li,
Hans-Matti Blencke
:
Bioactive compounds from marine resources
2017
Klara Stensvåg,
Tor Haug,
Ekaterina Mishchenko,
Hans-Matti Blencke
:
Marine natural resources – examples of health beneficial active components
2017
Ekaterina Mishchenko,
Hans-Matti Blencke,
Tor Haug,
Klara Stensvåg
:
Bioactive compounds from marine organisms in the High North - future antibiotics?
2017
Ekaterina Mishchenko,
Elizaveta Igumnova,
Johanna U Ericson Sollid,
Hans-Matti Blencke,
Reidunn Silje Lauksund,
Tor Haug
m.fl.:
Antibacterial marine natural product mimics for treatment of infections.
2017
Klara Stensvåg,
Tor Haug,
Ekaterina Mishchenko,
Hans-Matti Blencke
:
Marine antimicrobial compounds and their potential as lead compounds for novel antibiotics
2017
Ekaterina Mishchenko,
Johanna U Ericson Sollid,
Hans-Matti Blencke,
Tor Haug,
Elizabeth Aarag,
Klara Stensvåg
:
Antibacterial and Anti-biofilm Activity of Novel Marine Natural Product Mimics
2017
Ida Kristine Hansen,
Kine Ø. Hanssen,
Hans-Matti Blencke,
Klara Stensvåg,
Tor Haug
:
Antimicrobial peptides from Arctic ascidians
2017
Ekaterina Mishchenko,
Elizaveta Igumnova,
Hans-Matti Blencke,
Johanna U Ericson Sollid,
Elizabeth Aarag,
Tor Haug
m.fl.:
Antibacterial studies of compounds inspired by marine natural products
2016
Runar Gjerp Solstad,
Hans-Matti Blencke,
Ekaterina Mishchenko,
Chun Li,
Inger Rødum,
Tor Haug
m.fl.:
Bioactive peptides from marine sources
2016
Inger Kristine Rødum,
Chun Li,
Hans-Matti Blencke,
Klara Stensvåg,
Tor Haug
:
Antimicrobial peptides in the marine horse mussel, Modiolus modiolus
2015 DATA
Ekaterina Mishchenko,
Elizaveta Igumnova,
Hans-Matti Blencke,
Elizabeth Aarag,
Johanna U Ericson Sollid,
Tor Haug
m.fl.:
Antimicrobial studies of Marine Natural Product Mimics (MNPMs)
2015
Runar Gjerp Solstad,
Hans-Matti Blencke,
Yaroslav Alekseevich Andreev,
Magne Olav Sydnes,
Morten Kaare Moe,
Steinar Daae Johansen
m.fl.:
Bioactive peptides of Arctic marine invertebrates
2015
Chun Li,
Hans-Matti Blencke,
Tor Haug,
Klara Stensvåg
:
Fishing an immune receptor by microorganism affinity matrix
2015
Hans-Matti Blencke,
Chun Li,
Tor Haug,
Klara Stensvåg
:
Centrocin, an important contributor to green sea urchin self defense?
2015 DATA
Klara Stensvåg,
Hans-Matti Blencke,
Yaroslav Alekseevich Andreev,
Runar Gjerp Solstad,
Chun Li,
Magne Olav Sydnes
m.fl.:
Exploring the bioactive peptide space of arctic marine invertebrates
2014
Ekaterina Mishchenko,
Elizaveta Igumnova,
Hans-Matti Blencke,
Elizabeth Aarag,
Johanna U Ericson Sollid,
Tor Haug
m.fl.:
In vitro studies of the activities of marine natural product mimics on Stapylococcus epidermidis biofilms
2014
Ekaterina Mishchenko,
Elizaveta Mikhailovna Igumnova,
Johanna U Ericson Sollid,
Elizabeth Aarag,
Hans-Matti Blencke,
Tor Haug
m.fl.:
Antimicrobial and anti-biofilm studies of Marine Natural Product Mimics
2014
Magnus Støback Bjørsvik,
Klara Stensvåg,
Hans-Matti Blencke
:
Design av en transkripsjonssensor i Escherichia coli : til deteksjon av virkningsmåten til nyoppdagede antimikrobielle peptider
2013
Ekaterina Mishchenko,
Elizaveta Igumnova,
Hans-Matti Blencke,
Johanna U. Ericson Sollid,
Elizabeth Aarag,
Tor Haug
m.fl.:
Antibacterial and anti-biofilm studies of synthetic compounds derived from marine antimicrobial compounds
2013
Ekaterina Mishchenko,
Elizaveta Igumnova,
Elizabeth Aarag,
Johanna U. Ericson Sollid,
Tor Haug,
Hans-Matti Blencke
m.fl.:
Antimicrobial and anti-biofilm activities of novel synthetic compounds based on marine bioactive molecules
2013
Runar Gjerp Solstad,
Hans-Matti Blencke,
Yaroslav A. Andreev,
Magne Olav Sydnes,
Morten Kaare Moe,
Steinar Daae Johansen
m.fl.:
Exploring the bioactive peptide space of arctic marine invertebrates
2013
Ekaterina Mishchenko,
Elizaveta Igumnova,
Elizabeth Aarag,
Johanna U. Ericson Sollid,
Hans-Matti Blencke,
Tor Haug
m.fl.:
Antibacterial and anti-biofilm activity studies of synthetic compounds inspired by natural bioactive compounds
2013
Ekaterina Mishchenko,
Elizaveta Igumnova,
Johanna U. Ericson Sollid,
Elizabeth Aarag,
Hans-Matti Blencke,
Tor Haug
m.fl.:
Antimicrobial biofilm studies of synthetic compounds inspired by marine natural compounds
2013
Victoria Paulsen,
Klara Stensvåg,
Hans-Matti Blencke,
Tor Haug
:
The proline-arginine-rich antimicrobial peptide arasin 1 from the marine spider crab, Hyas araneus. Active derivatives - and mechanisms of action studies
2013
Chun Li,
Tor Haug,
Hans-Matti Blencke,
Klara Stensvåg
:
Antimicrobial peptides in the green sea urchin Strongylocentrotus droebachiensis
2012
Tor Haug,
Hans-Matti Blencke,
Sigmund Sperstad,
Chun Li,
Victoria Paulsen,
Margey Tadesse
m.fl.:
Antibiotics from the sea – a MabCent project
2012
sigmund Sperstad,
Tor Haug,
Victoria Paulsen,
Hans-Matti Blencke,
Olaf B. Styrvold,
Klara Stensvåg
:
Diversity of antimicrobial peptides from the spider crab, Hyas araneus
2011
Klara Stensvåg,
Chun Li,
Tor Haug,
Hans-Matti Blencke,
Olaf B. Styrvold
:
Characteristics and potential use of antimicrobial peptides from sea urchin, Strongylocentrotus droebachiensis
2011
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Publikasjoner utenom Cristin
Forskningsinteresser
I am interested in determining the mechanisms of action of novel antimicrobial compounds, therefore I try to develop easy to use and reliable assays for an initial characterization. I am also interested in developing specific assays for pinpointing molecular interactions of antimicrobial compounds with their target molecules inside bacteria.
Undervisning
FSK-2005, Bio-1601
