Hans-Matti Blencke
Førsteamanuensis/ mikrobiologi, bioprospektering, bioteknologi
Stillingsbeskrivelse
mikrobiologi
Vitenskapelige arbeidsområder
Manuel K Langer,
Ataur Rahman,
Hymonti Dey,
Trude Anderssen,
Hans-Matti Blencke,
Tor Haug
m.fl.:
Investigation of Tetrasubstituted Heterocycles Reveals Hydantoins as a Promising Scaffold for Development of Novel Antimicrobials with Membranolytic Properties
European Journal of Medicinal Chemistry 2023
Celine Sarah Marine Richard,
Hymonti Dey,
Frode Øyen,
Munazza Maqsood,
Hans-Matti Blencke
:
Outer Membrane Integrity-Dependent Fluorescence of the
Japanese Eel UnaG Protein in Live Escherichia coli Cells
Biosensors 2023 DOI
Manuel K Langer,
Ataur Rahman,
Hymonti Dey,
Trude Anderssen,
Francesco Zilioli,
Tor Haug
m.fl.:
A concise SAR-analysis of antimicrobial cationic amphipathic barbiturates for an improved activity-toxicity profile
Hymonti Dey,
Danijela Simonovic,
Ingrid Sofie Norberg-Schulz Hagen,
Terje Vasskog,
Elizabeth G. Aarag Fredheim,
Hans-Matti Blencke
m.fl.:
Synthesis and Antimicrobial Activity of Short Analogues of the Marine Antimicrobial Peptide Turgencin A: Effects of SAR Optimizations, Cys-Cys Cyclization and Lipopeptide Modifications
Marianne Hagensen Paulsen,
Magnus Engqvist,
Dominik Ausbacher,
Trude Anderssen,
Manuel K- Langer,
Tor Haug
m.fl.:
Amphipathic Barbiturates as Mimics of Antimicrobial Peptides and the Marine Natural Products Eusynstyelamides with Activity against Multi-resistant Clinical Isolates
Ida Kristine Østnes Hansen,
Johan Isaksson,
Aaron G. Poth,
Kine Østnes Hansen,
Aaron John Christian Andersen,
Céline Sarah Marine Richard
m.fl.:
Isolation and characterization of antimicrobial peptides with unusual disulfide connectivity from the colonial ascidian Synoicum turgens
Rui Han,
Hans-Matti Blencke,
Hao Cheng,
Chun Li
:
The antimicrobial effect of CEN1HC-Br against Propionibacterium acnes and its therapeutic and anti-inflammatory effects on acne vulgaris
Elizaveta Igumnova,
Ekaterina Mishchenko,
Tor Haug,
Hans-Matti Blencke,
Johanna U Ericson Sollid,
Elizabeth Aarag
m.fl.:
Amphipathic sulfonamidobenzamides mimicking small antimicrobial marine natural products; investigation of antibacterial and anti-biofilm activity against antibiotic resistant clinical isolates.
Bioorganic & Medicinal Chemistry 2018 DOI
Elizaveta Mikhailovna Igumnova,
Ekaterina Mishchenko,
Tor Haug,
Hans-Matti Blencke,
Johanna U Ericson Sollid,
Elizabeth Aarag
m.fl.:
Synthesis and antimicrobial activity of small cationic amphipathic aminobenzamide marine natural product mimics and evaluation of relevance against clinical isolates including ESBL–CARBA producing multi-resistant bacteria
Bioorganic & Medicinal Chemistry 2016 DOI
Victoria Paulsen,
Mario Mardirossian,
Hans-Matti Blencke,
Monica Benincasa,
Giulia Runti,
Matteo Nepa
m.fl.:
Inner membrane proteins YgdD and SbmA are required for the complete susceptibility of Escherichia coli to the proline rich antimicrobial peptide arasin 1(1–25)
Microbiology (Reading) 2016 DOI
Elizaveta Mikhailovna Igumnova,
Ekaterina Mishchenko,
Tor Haug,
Hans-Matti Blencke,
Johanna U Ericson Sollid,
Elizabeth G Aarag Fredheim
m.fl.:
Synthesis and antimicrobial activity of small cationic amphipathic aminobenzamide marine natural product mimics and evaluation of relevance against clinical isolates including ESBL–CARBA producing multi-resistant bacteria.
Bioorganic & Medicinal Chemistry 2016 DOI
Chun Li,
Hans-Matti Blencke,
Tor Haug,
Klara Stensvåg
:
Antimicrobial peptides in echinoderm host defense
Chun Li,
Hans-Matti Blencke,
Tor Haug,
Øyvind Jørgensen,
Klara Stensvåg
:
Expression of antimicrobial peptides in coelomocytes and embryos of the green sea urchin (Strongylocentrotus droebachiensis)
Victoria Paulsen,
Hans-Matti Blencke,
Monica Benincasa,
Tor Haug,
Jacobus Johannes Eksteen,
Olaf B. Styrvold
m.fl.:
Structure-activity relationships of the antimicrobial peptide arasin 1 - and mode of action studies of the N terminal, proline-rich region
Juan Fu,
Hanna-Kirsti S. Leiros,
Donatella De pascale,
Kenneth Johnson,
Hans-Matti Blencke,
Bjarne Landfald
:
Functional and structural studies of a novel cold-adapted esterase from an Arctic intertidal metagenomic library
Applied Microbiology and Biotechnology 2013 DOI
Camilla Bjørn,
Joakim Håkansson,
Emma Myhrman,
Veronika Sjøstrand,
Tor Haug,
Kerstin Lindgren
m.fl.:
Anti-infectious and anti-inflammatory effects of peptide fragments sequentially derived from the antimicrobial peptide centrocin 1 isolated from the green sea urchin, Strongylocentrotus droebachiensis
Ataur Rahman,
Manuel K Langer,
Hans-Matti Blencke,
Tor Haug,
Johanna U Ericson,
Morten B. Strøm
m.fl.:
Development of novel antimicrobial peptides: two classes with improved antimicrobial and antibiofilm activity
2023 PROSJEKT
Hymonti Dey,
Danijela Simonovic,
Ingrid Sofie Norberg-Schulz Hagen,
Terje Vasskog,
Elizabeth G. Aarag Fredheim,
Hans-Matti Blencke
m.fl.:
Antimicrobial activity and mode of action study of short cyclic analogues of the marine antimicrobial peptide Turgencin A
2023
Ida Kristine Østnes Hansen,
Tor Haug,
Klara Stensvåg,
Hans-Matti Blencke
:
Antimicrobial peptides from the Arctic ascidian Synoicum turgens
2022
Ataur Rahman,
Andrea Iselin Elvheim,
Christoffer Ågnes,
Ida Kristine Østnes Hansen,
Bjarne Landfald,
Hans-Matti Blencke
m.fl.:
Antimicrobial and antibiofilm potential of marine bacteria
2022
Klara Stensvåg,
Ekaterina Mishchenko,
Hans-Matti Blencke,
Andrea Iselin Elvheim,
Christoffer Ågnes,
Ataur Rahman
m.fl.:
Health beneficial antimicrobials from marine natural Arctic and sub-Arctic resources
2022 PROSJEKT
Hymonti Dey,
Danijela Simonovic,
Ingrid Sofie Norberg-Schulz Hagen,
Terje Vasskog,
Elizabeth G. Aarag Fredheim,
Hans-Matti Blencke
m.fl.:
Antimicrobial Activity and Mode of Action Study of Short
Analogues of The Marine Antimicrobial Peptide Turgencin A
2022
Hymonti Dey,
Danijela Simonovic,
Ingrid Sofie Norberg-Schulz Hagen,
Terje Vasskog,
Elizabeth G. Aarag Fredheim,
Hans-Matti Blencke
m.fl.:
Antimicrobial activity and mode of action study of short analogues of the marine antimicrobial peptide Turgencin A
2021
Sebastian Reidar Barriteau Siiri,
Tor Haug,
Klara Stensvåg,
Hans-Matti Blencke
:
Antimikrobielle forbindelser i sjøstjernen Asterias rubens og sjøpølsen Cucumaria frondosa
2019
Klara Stensvåg,
Jonathan Hira,
Ekaterina Mishchenko,
Hans-Matti Blencke,
Morten B. Strøm,
Bjarne Landfald
m.fl.:
Marine antimicrobial peptides – an inspiration for new compounds to fight bacteria
2019
Ekaterina Mishchenko,
Eric Juskewitz,
Hans-Matti Blencke,
Deanna Wolfson,
Johanna U Ericson Sollid
:
Antibacterial activity of novel marine-derived
”middle-space” molecules: mode of action studies
2018
Klara Stensvåg,
Tor Haug,
Runar Gjerp Solstad,
Ekaterina Mishchenko,
Chun Li,
Hans-Matti Blencke
:
Bioactive compounds from marine resources
2017
Klara Stensvåg,
Tor Haug,
Ekaterina Mishchenko,
Hans-Matti Blencke
:
Marine natural resources – examples of health beneficial active components
2017
Ekaterina Mishchenko,
Hans-Matti Blencke,
Tor Haug,
Klara Stensvåg
:
Bioactive compounds from marine organisms in the High North - future antibiotics?
2017
Ekaterina Mishchenko,
Elizaveta Igumnova,
Johanna U Ericson Sollid,
Hans-Matti Blencke,
Reidunn Silje Lauksund,
Tor Haug
m.fl.:
Antibacterial marine natural product mimics for treatment of infections.
2017
Klara Stensvåg,
Tor Haug,
Ekaterina Mishchenko,
Hans-Matti Blencke
:
Marine antimicrobial compounds and their potential as lead compounds for novel antibiotics
2017
Ekaterina Mishchenko,
Johanna U Ericson Sollid,
Hans-Matti Blencke,
Tor Haug,
Elizabeth Aarag,
Klara Stensvåg
:
Antibacterial and Anti-biofilm Activity of Novel Marine Natural Product Mimics
2017
Ida Kristine Hansen,
Kine Ø. Hanssen,
Hans-Matti Blencke,
Klara Stensvåg,
Tor Haug
:
Antimicrobial peptides from Arctic ascidians
2017
Ekaterina Mishchenko,
Elizaveta Igumnova,
Hans-Matti Blencke,
Johanna U Ericson Sollid,
Elizabeth Aarag,
Tor Haug
m.fl.:
Antibacterial studies of compounds inspired by marine natural products
2016
Runar Gjerp Solstad,
Hans-Matti Blencke,
Ekaterina Mishchenko,
Chun Li,
Inger Rødum,
Tor Haug
m.fl.:
Bioactive peptides from marine sources
2016
Inger Kristine Rødum,
Chun Li,
Hans-Matti Blencke,
Klara Stensvåg,
Tor Haug
:
Antimicrobial peptides in the marine horse mussel, Modiolus modiolus
2015 DATA
Ekaterina Mishchenko,
Elizaveta Igumnova,
Hans-Matti Blencke,
Elizabeth Aarag,
Johanna U Ericson Sollid,
Tor Haug
m.fl.:
Antimicrobial studies of Marine Natural Product Mimics (MNPMs)
2015
Runar Gjerp Solstad,
Hans-Matti Blencke,
Yaroslav Alekseevich Andreev,
Magne Olav Sydnes,
Morten Kaare Moe,
Steinar Daae Johansen
m.fl.:
Bioactive peptides of Arctic marine invertebrates
2015
Chun Li,
Hans-Matti Blencke,
Tor Haug,
Klara Stensvåg
:
Fishing an immune receptor by microorganism affinity matrix
2015
Hans-Matti Blencke,
Chun Li,
Tor Haug,
Klara Stensvåg
:
Centrocin, an important contributor to green sea urchin self defense?
2015 DATA
Klara Stensvåg,
Hans-Matti Blencke,
Yaroslav Alekseevich Andreev,
Runar Gjerp Solstad,
Chun Li,
Magne Olav Sydnes
m.fl.:
Exploring the bioactive peptide space of arctic marine invertebrates
2014
Ekaterina Mishchenko,
Elizaveta Igumnova,
Hans-Matti Blencke,
Elizabeth Aarag,
Johanna U Ericson Sollid,
Tor Haug
m.fl.:
In vitro studies of the activities of marine natural product mimics on Stapylococcus epidermidis biofilms
2014
Ekaterina Mishchenko,
Elizaveta Mikhailovna Igumnova,
Johanna U Ericson Sollid,
Elizabeth Aarag,
Hans-Matti Blencke,
Tor Haug
m.fl.:
Antimicrobial and anti-biofilm studies of Marine Natural Product Mimics
2014
Magnus Støback Bjørsvik,
Klara Stensvåg,
Hans-Matti Blencke
:
Design av en transkripsjonssensor i Escherichia coli : til deteksjon av virkningsmåten til nyoppdagede antimikrobielle peptider
2013
Ekaterina Mishchenko,
Elizaveta Igumnova,
Hans-Matti Blencke,
Johanna U. Ericson Sollid,
Elizabeth Aarag,
Tor Haug
m.fl.:
Antibacterial and anti-biofilm studies of synthetic compounds derived from marine antimicrobial compounds
2013
Ekaterina Mishchenko,
Elizaveta Igumnova,
Elizabeth Aarag,
Johanna U. Ericson Sollid,
Tor Haug,
Hans-Matti Blencke
m.fl.:
Antimicrobial and anti-biofilm activities of novel synthetic compounds based on marine bioactive molecules
2013
Runar Gjerp Solstad,
Hans-Matti Blencke,
Yaroslav A. Andreev,
Magne Olav Sydnes,
Morten Kaare Moe,
Steinar Daae Johansen
m.fl.:
Exploring the bioactive peptide space of arctic marine invertebrates
2013
Ekaterina Mishchenko,
Elizaveta Igumnova,
Elizabeth Aarag,
Johanna U. Ericson Sollid,
Hans-Matti Blencke,
Tor Haug
m.fl.:
Antibacterial and anti-biofilm activity studies of synthetic compounds inspired by natural bioactive compounds
2013
Ekaterina Mishchenko,
Elizaveta Igumnova,
Johanna U. Ericson Sollid,
Elizabeth Aarag,
Hans-Matti Blencke,
Tor Haug
m.fl.:
Antimicrobial biofilm studies of synthetic compounds inspired by marine natural compounds
2013
Victoria Paulsen,
Klara Stensvåg,
Hans-Matti Blencke,
Tor Haug
:
The proline-arginine-rich antimicrobial peptide arasin 1 from the marine spider crab, Hyas araneus. Active derivatives - and mechanisms of action studies
2013
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Publikasjoner utenom Cristin
Forskningsinteresser
I am interested in determining the mechanisms of action of novel antimicrobial compounds, therefore I try to develop easy to use and reliable assays for an initial characterization. I am also interested in developing specific assays for pinpointing molecular interactions of antimicrobial compounds with their target molecules inside bacteria.
Undervisning
FSK-2005, Bio-1601
