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Bilde av Hansen, Kine Østnes
Bilde av Hansen, Kine Østnes
Norges fiskerihøgskole kine.o.hanssen@uit.no +4777649272 48139867

Kine Østnes Hansen

Forsker, Marbio

Stillingsbeskrivelse

I work as an innovation researcher at Marbio. My responsibilities include:

  • The bioassays in our in vitro ADME assay platform. This platform contains assays that can determine compound solubility, membrane permeability, phase I and phase II metabolic stability and metabolite identification. These results give us a good indication regarding the pharmacokinetic properties of our compounds in an in vivo setting.  
  • Isolation and characterization of new bioactive compounds using mass-guided semi-preparative HPLC, HR-MS and NMR
  • Administrative tasks including application writing, compound logistics, project management and target product profiling.
  • Yannik Karl Heinz Schneider, Anton Liaimer, Johan Mattias Isaksson, Oda Sofie Bye Wilhelmsen, Jeanette Hammer Andersen, Kine Østnes Hansen m.fl.:
    Four new suomilides isolated from the cyanobacterium Nostoc sp. KVJ20 and proposal of their biosynthetic origin
    Frontiers in Microbiology 2023 ARKIV / DOI
  • Sara Ullsten-Wahlund, Guillaume Petit, Johan Mattias Isaksson, Ida Kristine Østnes Hansen, Yannik Karl Heinz Schneider, Marte Jenssen m.fl.:
    Identification of New Purpuroine Analogues from the Arctic Echinodermata Pteraster militaris That Inhibit FLT3-ITD+ AML Cell Lines
    International Journal of Molecular Sciences 2022 ARKIV / DOI
  • Kine Østnes Hansen, Ida Kristine Østnes Hansen, Céline Sarah Marine Richard, Marte Jenssen, Jeanette Hammer Andersen, Espen Holst Hansen :
    Antimicrobial Activity of Securamines From the Bryozoan Securiflustra securifrons
    Natural Product Communications 2021 ARKIV / DOI
  • Venke Kristoffersen, Marte Jenssen, Heba Raid Jawad, Johan Isaksson, Espen Hansen, Teppo Rämä m.fl.:
    Two Novel Lyso-Ornithine Lipids Isolated from an Arctic Marine Lacinutrix sp. Bacterium
    Molecules 2021 ARKIV / DOI
  • Marte Jenssen, Venke Kristoffersen, Kumar Motiram-Corral, Johan Isaksson, Teppo Rämä, Jeanette Hammer Andersen m.fl.:
    Chlovalicin B, a Chlorinated Sesquiterpene Isolated from the Marine Mushroom Digitatispora marina
    Molecules 2021 ARKIV / DOI
  • Marte Jenssen, Philip Rainsford, Eric Juskewitz, Jeanette Hammer Andersen, Espen Hansen, Johan Isaksson m.fl.:
    Lulworthinone, a New Dimeric Naphthopyrone From a Marine Fungus in the Family Lulworthiaceae With Antibacterial Activity Against Clinical Methicillin-Resistant Staphylococcus aureus Isolates
    Frontiers in Microbiology 2021 ARKIV / DOI
  • Yannik Karl-Heinz Schneider, Marte Jenssen, Johan Isaksson, Kine Østnes Hansen, Jeanette Hammer Andersen, Espen Hansen :
    Bioactivity of Serratiochelin A, a Siderophore Isolated from a Co-Culture of Serratia sp. and Shewanella sp.
    Microorganisms 14. juli 2020 ARKIV / DOI
  • Ida Kristine Østnes Hansen, Tomas Lövdahl, Danijela Simonovic, Kine Østnes Hansen, Aaron John Christian Andersen, hege Devold m.fl.:
    Antimicrobial activity of small synthetic peptides based on the marine peptide turgencin A: Prediction of antimicrobial peptide sequences in a natural peptide and strategy for optimization of potency
    International Journal of Molecular Sciences 2020 ARKIV / DOI
  • Ida Kristine Østnes Hansen, Johan Isaksson, Aaron G. Poth, Kine Østnes Hansen, Aaron John Christian Andersen, Céline Sarah Marine Richard m.fl.:
    Isolation and characterization of antimicrobial peptides with unusual disulfide connectivity from the colonial ascidian Synoicum turgens
    Marine Drugs 2020 ARKIV / DOI
  • Yannik Karl-Heinz Schneider, Kine Østnes Hansen, Johan Isaksson, Sara Maria Ullsten-Wahlund, Espen Hansen, Jeanette Hammer Andersen :
    Anti-Bacterial Effect and Cytotoxicity Assessment of Lipid 430 Isolated from Algibacter sp.
    Molecules 2019 ARKIV / DOI
  • Kine Østnes Hansen, Jeanette hammer Andersen, Annette Bayer, Sunil Kumar Pandey, Marianne Lorentzen, Kåre Bredeli Jørgensen m.fl.:
    Kinase chemodiversity from the Arctic: the breitfussins
    Journal of Medicinal Chemistry 2019 ARKIV / DOI
  • Raja Priyanka Mary Michael Siranjeevi, Espen Hansen, Johan Isaksson, Jeanette hammer Andersen, Kine Østnes Hansen :
    Dendrobeaniamine A, a new alkaloid from the Arctic marine bryozoan Dendrobeania murrayana
    Natural Product Research 2019 ARKIV / DOI
  • Aitor Moreno, Kine Østnes Hansen, Johan Isaksson :
    CSSF-CLIP-HSQMBC: measurement of heteronuclear coupling constants in severely crowded spectral regions
    RSC Advances 2019 ARKIV / DOI
  • Kine Østnes Hanssen, Johan Isaksson, Eirin Glomsaker, Jeanette hammer Andersen, Espen Hansen :
    Ponasterone A and F, Ecdysteroids from the Arctic Bryozoan Alcyonidium gelatinosum
    Molecules 2018 ARKIV / DOI
  • Raja Priyanka Mary Michael Siranjeevi, Kine Østnes Hanssen, Johan Isaksson, Jeanette hammer Andersen, Espen Hansen :
    A Novel Brominated Alkaloid Securidine A, Isolated from the Marine Bryozoan Securiflustra securifrons
    Molecules 2017 ARKIV / DOI
  • Kine Østnes Hansen, Johan Isaksson, Annette Bayer, Jostein a Johansen, Jeanette hammer Andersen, Espen Hansen :
    Securamine Derivatives from the Arctic Bryozoan Securiflustra securifrons
    Journal of natural products 2017 DOI
  • Justine Chervin, Marc Stierhof, Ming Him Tong, Doe Peace, Kine Østnes Hanssen, Dagmar S. Urgast m.fl.:
    Targeted Dereplication of Microbial Natural Products by High-Resolution MS and Predicted LC Retention Time
    Journal of natural products 2017 DOI
  • Eva Sonnenschein, Marc Stierhof, Stephan Goralczyk, Floriane M. Vabre, Leonie Pellissier, Kine Østnes Hanssen m.fl.:
    Pseudochelin A, a siderophore of Pseudoalteromonas piscicida S2040
    Tetrahedron 2017 DOI
  • Chiara Lauritano, Jeanette hammer Andersen, Espen Hansen, Marte Albrigtsen, Laura Escalera, Francesco Esposito m.fl.:
    Bioactivity Screening of Microalgae for Antioxidant, Anti-Inflammatory, Anticancer, Anti-Diabetes, and Antibacterial Activities
    Frontiers in Marine Science 2016 ARKIV / DOI
  • Lindon Moodie, Monika Zuzek, Robert Frangez, Jeanette hammer Andersen, Espen Hansen, Elisabeth Klungerbo Olsen m.fl.:
    Synthetic analogs of stryphnusin isolated from the marine sponge Stryphnus fortis inhibit acetylcholinesterase with no effect on muscle function or neuromuscular transmission
    Organic and biomolecular chemistry 2016 ARKIV / DOI
  • Ove Bergersen, Kine Østnes Hanssen, Terje Vasskog :
    Aerobic treatment of selective serotonin reuptake inhibitors in landfill leachate
    Environmental Sciences Europe 2015 ARKIV / DOI
  • Kine Østnes Hanssen, Gunnar Cervin, Rozenn Trepos, Julie Petitbois, Tor Haug, Espen Hansen m.fl.:
    The Bromotyrosine Derivative Ianthelline Isolated from the Arctic Marine Sponge Stryphnus fortis Inhibits Marine Micro- and Macrobiofouling
    Marine Biotechnology 2014 DOI
  • Ove Bergersen, Kine Østnes Hanssen, Terje Vasskog :
    Anaerobic treatment of sewage sludge containing selective serotonin reuptake inhibitors
    Bioresource Technology 2012 DOI
  • Kine Østnes Hanssen, Bruno Schuler, Antony J. Williams, Taye B. Demissie, Espen Hansen, Jeanette hammer Andersen m.fl.:
    A Combined Atomic Force Microscopy and Computational Approach for the Structural Elucidation of Breitfussin A and B: Highly Modified Halogenated Dipeptides from Thuiaria breitfussi
    Angewandte Chemie International Edition 2012 DOI
  • Kine Østnes Hanssen, Jeanette hammer Andersen, Trine Stiberg, Richard Alan Engh, Johan Svenson, Anne-Marie Genevière m.fl.:
    Antitumoral and Mechanistic Studies of Ianthelline Isolated from the Arctic Sponge Stryphnus fortis
    Anticancer Research 2012
  • Marit Huizer, Kristine Haugland, Agnethe Hansen Bæverud, Jon Brage Svenning, Kine Østnes Hansen, Espen Holst Hansen m.fl.:
    LC-Orbitrap MS/MS based untargeted lipidomics of marine microalgae
    2023
  • Magnus Andersland Antonsen, Kine Østnes Hansen, Espen Holst Hansen, Terje Vasskog :
    Use of metabolomics to identify secondary metabolites from marine algae biomass
    2023
  • Guillaume Petit, Kine Østnes Hansen :
    A fragment to bind them all
    2023
  • Guillaume Petit, Kine Østnes Hansen, Jeanette Hammer Andersen, Espen Holst Hansen, Annette Bayer, Bengt Erik Haug m.fl.:
    A fragment to bind them all: Characterising phorbazole fragments as pan-kinase inhibitor
    2023
  • Espen Holst Hansen, Kine Østnes Hansen, Jeanette Hammer Andersen :
    HotBio - a Horizon Europe MSCA Doctoral Network in Marine Biodiscovery
    2023
  • Yannik Karl Heinz Schneider, Anton Liaimer, Johan Mattias Isaksson, Oda Sofie Bye Wilhelmsen, Jeanette Hammer Andersen, Kine Østnes Hansen m.fl.:
    Corrigendum: Four new suomilides isolated from the cyanobacterium Nostoc sp. KVJ20 and proposal of their biosynthetic origin (Frontiers in Microbiology, (2023), 14, (1130018), 10.3389/fmicb.2023.1130018)
    Frontiers in Microbiology 2023 DOI
  • Espen Holst Hansen, Kine Østnes Hansen, Jeanette hammer Andersen :
    Nye legemidler fra havet?
    Dagens næringsliv 04. januar 2020 FULLTEKST
  • Priyanka Michael, Espen Hansen, Johan Isaksson, Jeanette hammer Andersen, Kine Østnes Hansen :
    Dendrobeaniamine A, a New Alkaloid from the Arctic Marine bryozoan Dendrobeania murrayana
    2019
  • Marte Jenssen, Jeanette Hammer Andersen, Teppo Rämä, Espen Holst Hansen, Kine Østnes Hansen, Chun Li :
    Biodiscovery of Antimicrobial Compounds from Arctic Marine Microorganisms
    2019
  • Anette O. Siiri, Kine Østnes Hanssen, Trine Stiberg, Bernt Igeland, Terje Vasskog, Johan Svenson m.fl.:
    Isolation and characterization of Ianthelline from an arctic sponge
    2011

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