Bilde av Blencke, Hans-Matti
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Bilde av Blencke, Hans-Matti
Førsteamanuensis/ mikrobiologi, bioprospektering, bioteknologi Norges fiskerihøgskole hans-matti.blencke@uit.no +4777644474 +4791827294 Her finner du meg

Hans-Matti Blencke


Stillingsbeskrivelse

mikrobiologi

Vitenskapelige arbeidsområder


  • Celine Sarah Marine Richard, Hymonti Dey, Frode Jacobsen Øyen, Munazza Maqsood, Hans-Matti Blencke :
    Outer Membrane Integrity-Dependent Fluorescence of the Japanese Eel UnaG Protein in Live Escherichia coli Cells
    Biosensors 2023 ARKIV / DOI
  • Manuel K Langer, Ataur Rahman, Hymonti Dey, Trude Anderssen, Hans-Matti Blencke, Tor Haug m.fl.:
    Investigation of tetrasubstituted heterocycles reveals hydantoins as a promising scaffold for development of novel antimicrobials with membranolytic properties
    European Journal of Medicinal Chemistry 2023 ARKIV / DOI
  • Hymonti Dey, Danijela Simonovic, Ingrid Sofie Norberg-Schulz Hagen, Terje Vasskog, Elizabeth G. Aarag Fredheim, Hans-Matti Blencke m.fl.:
    Synthesis and Antimicrobial Activity of Short Analogues of the Marine Antimicrobial Peptide Turgencin A: Effects of SAR Optimizations, Cys-Cys Cyclization and Lipopeptide Modifications
    International Journal of Molecular Sciences 2022 ARKIV / DOI
  • Manuel K Langer, Ataur Rahman, Hymonti Dey, Trude Anderssen, Francesco Zilioli, Tor Haug m.fl.:
    A concise SAR-analysis of antimicrobial cationic amphipathic barbiturates for an improved activity-toxicity profile
    European Journal of Medicinal Chemistry 2022 ARKIV / FULLTEKST / DATA / DOI
  • Marianne Hagensen Paulsen, Magnus Engqvist, Dominik Ausbacher, Trude Anderssen, Manuel K- Langer, Tor Haug m.fl.:
    Amphipathic Barbiturates as Mimics of Antimicrobial Peptides and the Marine Natural Products Eusynstyelamides with Activity against Multi-resistant Clinical Isolates
    Journal of Medicinal Chemistry 2021 ARKIV / DOI
  • Ida Kristine Østnes Hansen, Johan Isaksson, Aaron G. Poth, Kine Østnes Hansen, Aaron John Christian Andersen, Céline Sarah Marine Richard m.fl.:
    Isolation and characterization of antimicrobial peptides with unusual disulfide connectivity from the colonial ascidian Synoicum turgens
    Marine Drugs 2020 ARKIV / DOI
  • Elizaveta Igumnova, Ekaterina Mishchenko, Tor Haug, Hans-Matti Blencke, Johanna U Ericson Sollid, Elizabeth Aarag m.fl.:
    Amphipathic sulfonamidobenzamides mimicking small antimicrobial marine natural products; investigation of antibacterial and anti-biofilm activity against antibiotic resistant clinical isolates.
    Bioorganic & Medicinal Chemistry 2018 DOI
  • Rui Han, Hans-Matti Blencke, Hao Cheng, Chun Li :
    The antimicrobial effect of CEN1HC-Br against Propionibacterium acnes and its therapeutic and anti-inflammatory effects on acne vulgaris
    Peptides 2018 ARKIV / DOI
  • Victoria Paulsen, Mario Mardirossian, Hans-Matti Blencke, Monica Benincasa, Giulia Runti, Matteo Nepa m.fl.:
    Inner membrane proteins YgdD and SbmA are required for the complete susceptibility of Escherichia coli to the proline rich antimicrobial peptide arasin 1(1–25)
    Microbiology (Reading) 2016 DOI
  • Elizaveta Mikhailovna Igumnova, Ekaterina Mishchenko, Tor Haug, Hans-Matti Blencke, Johanna U Ericson Sollid, Elizabeth Aarag m.fl.:
    Synthesis and antimicrobial activity of small cationic amphipathic aminobenzamide marine natural product mimics and evaluation of relevance against clinical isolates including ESBL–CARBA producing multi-resistant bacteria
    Bioorganic & Medicinal Chemistry 2016 DOI
  • Elizaveta Mikhailovna Igumnova, Ekaterina Mishchenko, Tor Haug, Hans-Matti Blencke, Johanna U Ericson Sollid, Elizabeth G Aarag Fredheim m.fl.:
    Synthesis and antimicrobial activity of small cationic amphipathic aminobenzamide marine natural product mimics and evaluation of relevance against clinical isolates including ESBL–CARBA producing multi-resistant bacteria.
    Bioorganic & Medicinal Chemistry 2016 DOI
  • Chun Li, Hans-Matti Blencke, Tor Haug, Klara Stensvåg :
    Antimicrobial peptides in echinoderm host defense
    Developmental and Comparative Immunology 2015 ARKIV / DOI
  • Chun Li, Hans-Matti Blencke, Tor Haug, Øyvind Jørgensen, Klara Stensvåg :
    Expression of antimicrobial peptides in coelomocytes and embryos of the green sea urchin (Strongylocentrotus droebachiensis)
    Developmental and Comparative Immunology 2014 ARKIV / DOI
  • Hymonti Dey, Hans-Matti Blencke, Morten B. Strøm, Elizabeth G. Aarag Fredheim, Tor Haug :
    Antimicrobial activities and mechanisms of action of peptide analogues of marine origin
    2024 FULLTEKST
  • Ataur Rahman, Manuel Karl Langer, Bartosz Michno, Hans-Matti Blencke, Tor Haug, Johanna Ulrica Ericson m.fl.:
    Novel synthetic cationic antimicrobial peptides and their potential in combating antibiotic resistance
    2024
  • Ataur Rahman, Manuel Karl Langer, Bartosz Michno, Hans-Matti Blencke, Tor Haug, Morten B. Strøm m.fl.:
    Novel synthetic cationic antimicrobial peptides and their potential as antibiofilm agents
    2024
  • Ataur Rahman, Klara Stensvåg, Hans-Matti Blencke, Annette Bayer, Ekaterina Mischenko, de Freitas Almeida Gabriel Magno m.fl.:
    Bioactivity profiling and mode of action studies of antibacterial and antibiofilm agents of marine origin
    UiT Norges arktiske universitet 2024
  • Hymonti Dey, Danijela Simonovic, Celine Sarah Marine Richard, Ingrid Sofie Norberg-Schultz Hagen, Natascha Johansen, Frode Jacobsen Øyen m.fl.:
    Combining outer membrane active synthetic antimicrobial peptides with vancomycin or erythromycin increases antibacterial and antibiofilm activities
    2024
  • Ataur Rahman, Manuel K Langer, Hans-Matti Blencke, Tor Haug, Johanna U Ericson, Morten B. Strøm m.fl.:
    Development of novel antimicrobial peptides: two classes with improved antimicrobial and antibiofilm activity
    2023 PROSJEKT
  • Hymonti Dey, Danijela Simonovic, Ingrid Sofie Norberg-Schulz Hagen, Terje Vasskog, Elizabeth G. Aarag Fredheim, Hans-Matti Blencke m.fl.:
    Antimicrobial activity and mode of action study of short cyclic analogues of the marine antimicrobial peptide Turgencin A
    2023
  • Ataur Rahman, Manuel K Langer, Bartosz Michno, Hans-Matti Blencke, Tor Haug, Johanna U Ericson m.fl.:
    In vivo toxicity and activity of newly developed novel analogues of short-cationic antimicrobial peptides as novel antibacterial agents
    2023
  • Ataur Rahman, Manuel K Langer, Bartosz Michno, Hans-Matti Blencke, Tor Haug, Johanna U Ericson m.fl.:
    In vivo toxicity and activity of newly developed novel analogues of short-cationic antimicrobial peptides as novel antibacterial agents
    2023
  • Manuel K Langer, Ataur Rahman, Hymonti Dey, Trude Anderssen, Hans-Matti Blencke, Tor Haug m.fl.:
    Tetrasubstituted hydantoins: Novel membranolytic antimicrobials
    2023
  • Ataur Rahman, Christoffer Ågnes, Andrea Iselin Elvheim, Ida Kristine Østnes Hansen, Hans-Matti Blencke, Bjarne Landfald m.fl.:
    Molecular characterization of marine bacteria and their potential as being antimicrobial producers: a pilot study using co-cultures
    2023
  • Charlotte Kit Mun Brocklesby, Klara Stensvåg, Hans-Matti Blencke :
    The use of traditional and unconventional culturing methods for the discovery of antimicrobial compounds derived from marine microorganisms
    UiT Norges arktiske universitet 2023
  • Hymonti Dey, Danijela Simonovic, Ingrid Sofie Norberg-Schulz Hagen, Terje Vasskog, Elizabeth G. Aarag Fredheim, Hans-Matti Blencke m.fl.:
    Antimicrobial Activity and Mode of Action Study of Short Analogues of The Marine Antimicrobial Peptide Turgencin A
    2022
  • Klara Stensvåg, Ekaterina Mishchenko, Hans-Matti Blencke, Andrea Iselin Elvheim, Christoffer Ågnes, Ataur Rahman m.fl.:
    Health beneficial antimicrobials from marine natural Arctic and sub-Arctic resources
    2022 PROSJEKT
  • Ataur Rahman, Andrea Iselin Elvheim, Christoffer Ågnes, Ida Kristine Østnes Hansen, Bjarne Landfald, Hans-Matti Blencke m.fl.:
    Antimicrobial and antibiofilm potential of marine bacteria
    2022
  • Ida Kristine Østnes Hansen, Tor Haug, Klara Stensvåg, Hans-Matti Blencke :
    Antimicrobial peptides from the Arctic ascidian Synoicum turgens
    UiT Norges arktiske universitet 2022
  • Hymonti Dey, Danijela Simonovic, Ingrid Sofie Norberg-Schulz Hagen, Terje Vasskog, Elizabeth G. Aarag Fredheim, Hans-Matti Blencke m.fl.:
    Antimicrobial activity and mode of action study of short analogues of the marine antimicrobial peptide Turgencin A
    2021
  • Sebastian Reidar Barriteau Siiri, Tor Haug, Klara Stensvåg, Hans-Matti Blencke :
    Antimikrobielle forbindelser i sjøstjernen Asterias rubens og sjøpølsen Cucumaria frondosa
    UiT Norges arktiske universitet 2019
  • Klara Stensvåg, Jonathan Hira, Ekaterina Mishchenko, Hans-Matti Blencke, Morten B. Strøm, Bjarne Landfald m.fl.:
    Marine antimicrobial peptides – an inspiration for new compounds to fight bacteria
    2019
  • Ekaterina Mishchenko, Eric Juskewitz, Hans-Matti Blencke, Deanna Wolfson, Johanna U Ericson Sollid :
    Antibacterial activity of novel marine-derived ”middle-space” molecules: mode of action studies
    2018
  • Ekaterina Mishchenko, Hans-Matti Blencke, Tor Haug, Klara Stensvåg :
    Bioactive compounds from marine organisms in the High North - future antibiotics?
    2017
  • Klara Stensvåg, Tor Haug, Ekaterina Mishchenko, Hans-Matti Blencke :
    Marine natural resources – examples of health beneficial active components
    2017
  • Klara Stensvåg, Tor Haug, Ekaterina Mishchenko, Hans-Matti Blencke :
    Marine antimicrobial compounds and their potential as lead compounds for novel antibiotics
    2017
  • Ekaterina Mishchenko, Johanna U Ericson Sollid, Hans-Matti Blencke, Tor Haug, Elizabeth Aarag, Klara Stensvåg :
    Antibacterial and Anti-biofilm Activity of Novel Marine Natural Product Mimics
    UiT Norges arktiske universitet 2017
  • Klara Stensvåg, Tor Haug, Runar Gjerp Solstad, Ekaterina Mishchenko, Chun Li, Hans-Matti Blencke :
    Bioactive compounds from marine resources
    2017
  • Ekaterina Mishchenko, Elizaveta Igumnova, Johanna U Ericson Sollid, Hans-Matti Blencke, Reidunn Silje Lauksund, Tor Haug m.fl.:
    Antibacterial marine natural product mimics for treatment of infections.
    2017
  • Ida Kristine Hansen, Kine Ø. Hanssen, Hans-Matti Blencke, Klara Stensvåg, Tor Haug :
    Antimicrobial peptides from Arctic ascidians
    2017
  • Ekaterina Mishchenko, Elizaveta Igumnova, Hans-Matti Blencke, Johanna U Ericson Sollid, Elizabeth Aarag, Tor Haug m.fl.:
    Antibacterial studies of compounds inspired by marine natural products
    2016
  • Runar Gjerp Solstad, Hans-Matti Blencke, Ekaterina Mishchenko, Chun Li, Inger Rødum, Tor Haug m.fl.:
    Bioactive peptides from marine sources
    2016
  • Inger Kristine Rødum, Chun Li, Hans-Matti Blencke, Klara Stensvåg, Tor Haug :
    Antimicrobial peptides in the marine horse mussel, Modiolus modiolus
    2015 DATA
  • Hans-Matti Blencke, Chun Li, Tor Haug, Klara Stensvåg :
    Centrocin, an important contributor to green sea urchin self defense?
    2015 DATA
  • Ekaterina Mishchenko, Elizaveta Igumnova, Hans-Matti Blencke, Elizabeth Aarag, Johanna U Ericson Sollid, Tor Haug m.fl.:
    Antimicrobial studies of Marine Natural Product Mimics (MNPMs)
    2015
  • Chun Li, Hans-Matti Blencke, Tor Haug, Klara Stensvåg :
    Fishing an immune receptor by microorganism affinity matrix
    2015
  • Runar Gjerp Solstad, Hans-Matti Blencke, Yaroslav Alekseevich Andreev, Magne Olav Sydnes, Morten Kaare Moe, Steinar Daae Johansen m.fl.:
    Bioactive peptides of Arctic marine invertebrates
    2015
  • Klara Stensvåg, Hans-Matti Blencke, Yaroslav Alekseevich Andreev, Runar Gjerp Solstad, Chun Li, Magne Olav Sydnes m.fl.:
    Exploring the bioactive peptide space of arctic marine invertebrates
    2014
  • Ekaterina Mishchenko, Elizaveta Mikhailovna Igumnova, Johanna U Ericson Sollid, Elizabeth Aarag, Hans-Matti Blencke, Tor Haug m.fl.:
    Antimicrobial and anti-biofilm studies of Marine Natural Product Mimics
    2014
  • Ekaterina Mishchenko, Elizaveta Igumnova, Hans-Matti Blencke, Elizabeth Aarag, Johanna U Ericson Sollid, Tor Haug m.fl.:
    In vitro studies of the activities of marine natural product mimics on Stapylococcus epidermidis biofilms
    2014

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    Forskningsinteresser

    I am interested in determining the mechanisms of action of novel antimicrobial compounds, therefore I try to develop easy to use and reliable assays for an initial characterization. I am also interested in developing specific assays for pinpointing molecular interactions of antimicrobial compounds with their target molecules inside bacteria.

    Undervisning

    Generell mikrobiologi Bio-2601


    Medlem i forskningsgruppe