Foto: Christian Halvorsen
Christer Einvik
Swapnil Bhavsar,
Lotte Olsen,
Cecilie Løkke,
Jan Koster,
Trond Flægstad,
Christer Einvik
:
Hsa-miR-323a-3p functions as a tumor suppressor and targets STAT3 in neuroblastoma cells
Peter Utnes,
Cecilie Løkke,
Trond Flægstad,
Christer Einvik
:
Clinically Relevant Biomarker Discovery in High-Risk Recurrent Neuroblastoma
Roth Sarah Andrea,
Øyvind Holsbø Hald,
Steffen Fuchs,
Cecilie Løkke,
Ingvild Mikkola,
Trond Flægstad
m.fl.:
MicroRNA-193b-3p represses neuroblastoma cell growth via downregulation of Cyclin D1, MCL-1 and MYCN
Swapnil Parashram Bhavsar,
Cecilie Løkke,
Trond Flægstad,
Christer Einvik
:
Hsa-miR-376c-3p targets cyclin D1 and induces G1-cell cycle arrest in neuroblastoma cells
Øyvind Holsbø Hald,
Lotte Olsen,
Gabriel Gallo-Oller,
Lotta Helena Maria Elfman,
Cecilie Løkke,
Per Kogner
m.fl.:
Inhibitors of ribosome biogenesis repress the growth of MYCN-amplified neuroblastoma.
Sarah A Roth,
Erik Knutsen,
Tonje Fiskaa,
Peter Andree Utnes,
Swapnil Parashram Bhavsar,
Øyvind Hald
m.fl.:
Next generation sequencing of microRNAs from isogenic neuroblastoma cell lines isolated before and after treatment
Malin Wickström,
Cecilia Dyberg,
Jelena Milosevic,
Christer Einvik,
Raul Calero,
Baldur Sveinbjørnsson
m.fl.:
Wnt/β-catenin pathway regulates MGMT gene expression in cancer and inhibition of Wnt signalling prevents chemoresistance
Bjørn Helge Haug,
Øyvind Hald,
Peter Utnes,
Sarah A Roth,
Cecilie Løkke,
Trond Flægstad
m.fl.:
Exosome-like extracellular vesicles from MYCN-amplified neuroblastoma cells contain oncogenic miRNAs
Anticancer Research 2015 ARKIV
Hanna Zirath,
Anna Frenzel,
Ganna Oliynyk,
Lova Segerstrom,
Ulrica K. Westermark,
Karin Larsson
m.fl.:
MYC inhibition induces metabolic changes leading to accumulation of lipid droplets in tumor cells
Jochen Buechner,
Christer Einvik
:
N-myc and Noncoding RNAs in Neuroblastoma
Jørn Remi Henriksen,
Jochen Büchner,
Cecilie Løkke,
Trond Flaegstad,
Christer Einvik
:
Inhibition of Gene Function in Mammalian Cells Using Short-Hairpin RNA (shRNA)
Bjørn Helge Haug,
Jørn Remi Henriksen,
Jochen Buechner,
Dirk Geerts,
Ellen Tømte,
Per Kogner
m.fl.:
MYCN-regulated miRNA-92 inhibits secretion of the tumor suppressor DICKKOPF-3 (DKK3) in neuroblastoma
Jørn Remi Henriksen,
Bjørn Helge Haug,
Jochen Büchner,
Ellen Tømte,
Cecilie Løkke,
Trond Flaegstad
m.fl.:
Conditional expression of retrovirally delivered anti-MYCN shRNA as an in vitro model system to study neuronal differentiation in MYCN-amplified neuroblastoma
Jochen Büchner,
Jørn Remi Henriksen,
Bjørn Helge Haug,
Ellen Tømte,
Trond Flaegstad,
Christer Einvik
:
Inhibition of mir-21, which is up-regulated during MYCN knockdown-mediated differentiation, does not prevent differentiation of neuroblastoma cells
Jochen Buechner,
Ellen Tømte,
Bjørn Helge Haug,
Jørn Remi Henriksen,
Cecilie Løkke,
Trond Flægstad
m.fl.:
Tumour-suppressor microRNAs let-7 and mir-101 target the proto-oncogene MYCN and inhibit cell proliferation in MYCN-amplified neuroblastoma
Henrik Nielsen,
christer Einvik,
Thomas E Lentz,
MM Hedegaard,
Steinar Johansen
:
A conformational switch in the DiGIR1 ribozyme involved in release and folding of the downstream I-DirI mRNA
B Beckert,
Henrik Nielsen,
christer Einvik,
Steinar Johansen,
E Westhof,
B Masquida
:
Molecular modelling of the GIR1 branching ribozyme gives new insight into evolution of structurally related ribozymes
Jørn Remi Henriksen,
cecilie LØkke,
Martin Hammerø,
Dirk Geerts,
R Versteeg,
Trond Flaegstad
m.fl.:
Comparison of RNAi efficiency mediated by tetracycline-responsive H1 and U6 promoter variants in mammalian cell lines
Odd Gunnar Wikmark,
Christer Einvik,
Johan F De Jonckheere,
Steinar Daae Johansen
:
Short-term sequence evolution and vertical inheritance of the Naegleria twin-ribozyme group I intron
Odd Gunnar Wikmark,
Christer Einvik,
JF De Jonckheere,
Steinar Johansen
:
Short-term sequence evolution and vertical inheritance of the Naegleria twin-ribozyme group I intron
BMC Evolutionary Biology 2006 ARKIV
Tonje Fiskaa,
Eirik Wasmuth Lundblad,
Jørn Remi Henriksen,
Steinar Johansen,
Christer Einvik
:
RNA reprogramming of alpha-mannosidase mRNA sequences in vitro by myxomycete group IC1 and IE ribozymes
The FEBS Journal 2006 ARKIV
Eirik Wasmuth Lundblad,
Christer Einvik,
S Rønning,
Kari B. Haugli,
Steinar Johansen
:
Twelve group I Introns in the same pre-rRNA transcript of the myxomycete Fuligo septica: RNA processing and evolution
Molecular Biology and Evolution (MBE) 2004 ARKIV
Christer Einvik,
Tonje Fiskaa,
Eirik Wasmuth Lundblad,
Steinar Johansen
:
Optimization and application of the group I ribozyme trans-splicing reaction
Methods in molecular biology 2004 ARKIV
Henrik Nielsen,
Tonje Fiskaa,
Åsa Birna Birgisdottir,
Peik Haugen,
christer Einvik,
Steinar Johansen
:
The ability to form full-length intron RNA circles is a general property of nuclear group I introns
RNA: A publication of the RNA Society 2003 ARKIV
Steinar Daae Johansen,
morten Andreassen,
Åsa birna Birgisdottir,
Dag-Hugo Coucheron,
Christer Einvik,
Tonje Fiskaa
m.fl.:
Group I introns are very common in nuclear SSU rDNA and LSU rDNA of Myxomycetes
Scripta Botanica Belgica 2002 ARKIV
Steinar Johansen,
christer Einvik,
Henrik Nielsen
:
DiGIR1 and NaGIR1: naturally occurring group I-like ribozymes with unique core organization and evolved biological role
Biochimie 2002 ARKIV
christer Einvik,
Henrik Nielsen,
R Nour,
Steinar Johansen
:
Flanking sequences with essential role in hydrolysis of a self-cleaving group I-like ribozyme
Nucleic Acids Research (NAR) 2000 ARKIV
Yusuke Suenaga,
Christer Einvik,
Atsushi Takatori,
Yuyan Zhu
:
Editorial: Molecular Mechanisms and Treatment of MYCN-Driven Tumors
Trond Flægstad,
Bjørn Helge Haug,
Jochen Buechner,
Jørn Remi Henriksen,
Per Kogner,
Tommy Martinson
m.fl.:
MYCN-REGULATED MIRNA-92 INHIBITS SECRETION OF THE TUMOR SUPPRESSOR DICKKOPF-3 (DKK3) IN NEUROBLASTOMA
Pediatric Blood & Cancer 2011 ARKIV
Trond Flaegstad,
christer Einvik,
Jørn Remi Henriksen
:
Targeted MYCN suppression and its effect on miRNA in neuroblastoma
UiT Norges arktiske universitet 03. desember 2010 ARKIV
Jørn Remi Henriksen,
Jochen Büchner,
Bjørn Helge Haug,
christer Einvik,
Trond Flaegstad
:
Combination of RA Treatment and MYCN-knockdown in MYCN Amplified Neuroblastoma
2010 ARKIV
Bjørn Helge Haug,
Jørn Remi Henriksen,
Baldur Sveinbjørnsson,
Trond Flaegstad,
christer Einvik
:
The tumour suppressor DKK3 is a direct target of MYCN regulated miRNAs
2010 ARKIV
Jørn Remi Henriksen,
Bjørn Helge Haug,
Jochen Büchner,
cecilie LØkke,
Trond Flaegstad,
christer Einvik
:
Conditional MYCN knockdown using shRNAs encoded by retrovirus vectors
2010 ARKIV
Trond Flaegstad,
Jochen Büchner,
Jørn Remi Henriksen,
cecilie LØkke,
Ellen Tømte,
Bjørn Helge Haug
m.fl.:
MYCN PARTICIPATES IN A REGULATORY MIRNA NETWORK IN MYCN-AMPLIFIED NEUROBLASTOMA
Pediatric Blood & Cancer 2009 ARKIV
Jochen Büchner,
Jørn Remi Henriksen,
cecilie LØkke,
Trond Flaegstad,
christer Einvik
:
Effect of MYCN downregulation on microRNA expression in neuroblastoma
2008 ARKIV
Jochen Büchner,
Jørn Remi Henriksen,
cecilie LØkke,
Trond Flaegstad,
christer Einvik
:
MicroRNA-101 as a potential regulator of MCYN expression in neuroblastoma
2008 ARKIV
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Forskningsinteresser
Onkologi (forskningsgruppe for pediatri)