Foto: Bjørn-Kåre Iversen
Ole Morten Seternes
Stillingsbeskrivelse
Professor i Farmakologi og gruppeleder for forskningsgruppen i Celle signallering og målrettet terapi. Emneleder for Farmakologi
Fadia Boudghene-Stambouli,
Mathilde Soulez,
Natalia Ronkina,
Anneke Dörrie,
Alexey Kotlyarov,
Ole Morten Seternes
m.fl.:
On the Therapeutic Potential of ERK4 in Triple-Negative Breast Cancer
Benedicte Sjo Tislevoll,
Monica Hellesøy,
Oda Helen Eck Fagerholt,
Stein-Erik Gullaksen,
Aashish Srivastava,
Even Birkeland
m.fl.:
Early response evaluation by single cell signaling profiling in acute myeloid leukemia
Erik Knutsen,
Saikat Das Sajib,
Tonje Fiskaa,
James Bradley Lorens,
Thorarinn Gudjonsson,
Gunhild Mari Mælandsmo
m.fl.:
Identification of a core EMT signature that separates basal-like breast cancers into partial- and post-EMT subtypes
Lisa Zeyen Øyås,
Ole Morten Seternes,
Ingvild Mikkola
:
Crosstalk between p38 MAPK and GR Signaling
Joaquim Javary,
Eugénie Goupil,
Mathilde Soulez,
Evgeny Kanshin,
Antoine Bouchard,
Ole Morten Seternes
m.fl.:
Phosphoproteomic analysis identifies supervillin as an ERK3 substrate regulating cytokinesis and cell ploidy
Dennis Bela-Ong,
Linn Greiner-Tollersrud,
Yorick Andreas van der Wal,
Ingvill Jensen,
Ole Morten Seternes,
Jorunn Jørgensen
:
Infection and microbial molecular motifs modulate transcription of the interferon-inducible gene ifit5 in a teleost fish
Anup Shrestha,
Henrike Bruckmüller,
Hanne Kildalsen,
Gurjit Kaur,
Matthias Gaestel,
Hilde Ljones Wetting
m.fl.:
Phosphorylation of steroid receptor coactivator-3 (SRC-3) at serine 857 is regulated by the p38 MAPK-MK2 axis and affects NF-κB-mediated transcription
Ole Morten Seternes,
Andrew M Kidger,
Stephen M Keyse
:
Dual-specificity MAP kinase phosphatases in health and disease
Anna Lucja Czarna,
Wang Jinhua,
Diana Zelencova,
Yao Liu,
Xianming Deng,
Hwan Geun Choi
m.fl.:
Novel Scaffolds for Dual Specificity Tyrosine-Phosphorylation-Regulated Kinase (DYRK1A) Inhibitors
Maria Perander,
Rania Al-Mahdi,
Thomas Clemens Jensen,
Jennifer Ann Lillebo Nunn,
Hanne Kildalsen,
Bjarne Herold Johansen
m.fl.:
Regulation of atypical MAP kinases ERK3 and ERK4 by the phosphatase DUSP2
Maria Perander,
Stephen M Keyse,
Ole Morten Seternes
:
New insights into the activation, interaction partners and possible functions of MK5/PRAK
Frontiers in Bioscience 2016
Tonje Fiskaa,
Erik Knutsen,
Malene Nikolaisen,
Tor Erik Jørgensen,
Steinar Daae Johansen,
maria Perander
m.fl.:
Distinct small RNA signatures in extracellular vesicles derived from breast cancer cell lines
Jennifer L. Whiting,
Leah Ogier,
Katherine A Forbush,
Paula Bucko,
Janani Gopalan,
Ole Morten Seternes
m.fl.:
AKAP220 manages apical actin networks that coordinate aquaporin-2 location and renal water reabsorption
Proceedings of the National Academy of Sciences of the United States of America (PNAS) 2016 DOI
Sampada Satchidanand Bhagwat,
Anett Kristin Larsen,
Ole Morten Seternes,
Berit Bang
:
Mixed exposure to bacterial lipopolysaccharide and seafood proteases augments inflammatory signalling in an airway epithelial cell model (A549)
Ka Bian,
Naveen Reddy Muppani,
Lobna Elkhadragy,
Wei Wang,
Cheng Zhang,
Tenghui Chen
m.fl.:
ERK3 regulates TDP2-mediated DNA damage response and chemoresistance in lung cancer cells
Rania Al-Mahdi,
Nouf Babteen,
Kiruthikah Thillai,
Mark Holt,
Bjarne Herold Johansen,
Hilde Ljones Wetting
m.fl.:
A novel role for atypical MAPK kinase ERK3 in regulating breast cancer cell morphology and migration
Cell Adhesion & Migration 2015 DOI
Jennifer L. Whiting,
Patrick J. Nygren,
Brian J. Tunquist,
Lorene K. Langeberg,
Ole Morten Seternes,
John D. Scott
:
Protein kinase A opposes the phosphorylation-dependent recruitment of glycogen synthase kinase 3β to A-kinase Anchoring Protein 220
Sampada Satchidanand Bhagwat,
Anett Kristin Larsen,
Jan-Olof Winberg,
Ole Morten Seternes,
Berit Bang
:
Salmon and king crab trypsin stimulate interleukin-8 and matrix metalloproteinases via protease-activated receptor-2 in the skin keratinocytic HaCaT cell line
Food and Chemical Toxicology (FCT) 2014 DOI
Anett Kristin Larsen,
kurt Kristiansen,
Ingebrigt Sylte,
Ole Morten Seternes,
Berit Bang
:
Differences in PAR-2 activating potential by king crab (Paralithodes camtschaticus), salmon (Salmo salar), and bovine (Bos taurus) trypsin
Erik Knutsen,
Tonje Fiskaa,
anita Ursvik,
Tor Erik Jørgensen,
maria Perander,
Eiliv Lund
m.fl.:
Performance Comparison of Digital microRNA Profiling Technologies Applied on Human Breast Cancer Cell Lines
Ilona Urbarova,
Bård Ove Karlsen,
Siri Okkenhaug,
Ole Morten Seternes,
Steinar Johansen,
Åse Emblem
:
Digital Marine Bioprospecting: Mining New Neurotoxin Drug Candidates from the Transcriptomes of Cold-Water Sea Anemones
Anett Kristin Larsen,
ole morten Seternes,
Merethe Larsen,
Hideki Kishimura,
Galina N Rudenskaya,
Berit Bang
:
Purified sardine and king crab trypsin display individual differences in PAR-2-, NF-kappa B-, and IL-8 signaling
ole morten Seternes,
Bjarne Herold Johansen,
Beate Hegge,
Mona Johannessen,
Stephen M Keyse,
Ugo Moens
:
Both Binding and Activation of p38 Mitogen-Activated Protein Kinase (MAPK) Play Essential Roles in Regulation of the Nucleocytoplasmic Distribution of MAPK-Activated Protein Kinase 5 by Cellular Stress
Molecular and Cellular Biology 2010 DOI
Steinar D. Johansen,
Åse Emblem,
Bård Ove Karlsen,
Siri Okkenhaug,
Hilde Hansen,
Truls Moum
m.fl.:
Approaching marine bioprospecting in hexacorals by RNA deep sequencing
New Biotechnology 2010 DOI
espen Åberg,
Knut Martin Torgersen,
Bjarne Herold Johansen,
Stephen M Keyse,
maria Perander,
ole morten Seternes
:
Docking of PRAK/MK5 to the Atypical MAPKs ERK3 and ERK4 Defines a Novel MAPK Interaction Motif
Journal of Biological Chemistry 2009 DOI
Anett Kristin Larsen,
ole morten Seternes,
Merethe Larsen,
lisbeth Aasmoe,
Berit Bang
:
Salmon trypsin stimulates the expression of interleukin-8 via protease-activated receptor-2
Toxicology and Applied Pharmacology 2008 DOI
Tom Egil Hansen,
Pål Puntervoll,
A.W. Borgland,
ole morten Seternes,
Gerald Eigen,
Jorunn B Jørgensen
m.fl.:
Atlantic salmon possess three mitogen activated protein kinase kinase 6 paralogs responding differently to stress
The FEBS Journal 2008 DOI
maria Perander,
Stephen M Keyse,
ole morten Seternes
:
Does MK5 reconcile classical and atypical MAP kinases?
Frontiers in Bioscience 2008
maria Perander,
espen Åberg,
Bjarne Herold Johansen,
Bo Dreyer,
Ingrid Jenny Guldvik,
heidi Outzen
m.fl.:
The Ser(186) phospho-acceptor site within ERK4 is essential for its ability to interact with and activate PRAK/MK5
Biochemical Journal 2008 DOI
espen Michaelsen,
maria Perander,
Bjarne Herold Johansen,
Catherine Julien,
Sylvain Meloche,
Stephen M Keyse
m.fl.:
Regulation of MAPK-activated protein kinase 5 activity and subcellular localization by the atypical MAPK ERK4/MAPK4
Journal of Biological Chemistry 2006
Mona Johannessen,
Marit Pedersen Delghandi,
Ole Morten Seternes,
Bjarne Johansen,
Ugo Lionel Moens
:
Synergistic activation of CREB-mediated transcription by forskolin and phorbol ester requires PKC and depends on the glutamine-rich Q2 transactivation domain
Cellular Signalling 2004
Ole Morten Seternes,
Theresa Mikalsen,
Bjarne Johansen,
Espen Michaelsen,
CG Armstrong,
NA Morrice
m.fl.:
Activation of MK5/PRAK by the atypical MAP kinase ERK3 defines a novel signal transduction pathway
EMBO Journal 2004 DOI
Nico Hendrickx,
Cédric Volanti,
Ugo Moens,
ole morten Seternes,
Peter De Witte,
Jackie R Vandenheede
:
Up-regulation of cyclooxygenase-2 and apoptosis resistance by p38 MAPK in hypericin-mediated photodynamic therapy of human cancer cells
Journal of Biological Chemistry 2004
Mona Johannessen,
Petter Angell Olsen,
Rita Irene Sørensen,
Bjarne Johansen,
Ole Morten Seternes,
Ugo Lionel Moens
:
A role of the TATA box and the general co-activator hTAFII130/135 in promoter-specific trans-activation by simian virus 40 small t antigen
Journal of General Virology 2003 DOI
Mona Johannessen,
Petter Angell Olsen,
Bjarne Johansen,
Ole Morten Seternes,
Ugo Lionel Moens
:
Activation of the coactivator foru-and-a-half-LIM-only protein FHL2 and the c-fos promoter through inhibition of protein phosphatase 2A
Biochemical Pharmacology 2003
Nico Hendrickx,
Cédric Volanti,
Ugo Lionel Moens,
Ole Morten Seternes,
Peter De Witte,
Jackie R Vandenheede
m.fl.:
Up-regulation of cyclooxygenase-2 and apoptosis resistance by p38 MAPK in hypericin-mediated photodynamic therapy of human cancer cells
Journal of Biological Chemistry 2003 DOI
Benedicte Sjo Tislevoll,
Monica Hellesøy,
Oda Helen Eck Fagerholt,
Stein-Erik Gullaksen,
Aashish Srivastava,
Even Birkeland
m.fl.:
Author Correction: Early response evaluation by single cell signaling profiling in acute myeloid leukemia (Nature Communications, (2023), 14, 1, (115), 10.1038/s41467-022-35624-4)
Nature Communications 2023 DOI
Berit Bang,
Anett Kristin Larsen,
Sampada Satchidanand Bhagwat,
Nabin Malla,
Ole Morten Seternes,
Jan-Olof Winberg
:
Seafood proteases present in workplace bioaerosols – effects on inflammatory pathways in skin and airway cell models.
2016
Berit Bang,
Anett Kristin Larsen,
Sampada Satchidanand Bhagwat,
Nabin Malla,
Ole Morten Seternes,
Jan-Olof Winberg
:
Seafood proteases present in workplace bioaerosols – effects on inflammatory pathways in skin and airway cell models.
2016
espen Åberg,
Ole Morten Seternes,
Richard Alan Engh,
Franz Gruber
:
Fra Mutasjon til Medisin
2013
maria Perander,
Trine Stiberg,
Lene Elisabeth Myhren,
Espen Hansen,
ole morten Seternes,
Lars Herfindal
m.fl.:
Characterization of cytotoxic activities in extracts from two marine invertebrates
2011
Steinar Daae Johansen,
morten Andreassen,
Igor Babiak,
Teshome Bizuayehu,
Dag-Hugo Coucheron,
M. Raafat El-Gewely
m.fl.:
Investigating miRNAs and transcriptomes at our local SOLiD sequencing facility
2011
Anett Kristin Larsen,
Merethe Larsen,
Ole Morten Seternes,
Berit Bang
:
Proteases in Seafood as activators of inflammatory reactions in airway epithelial cells
2011
Erik Knutsen,
morten Andreassen,
Tonje Fiskaa,
anita Ursvik,
Eiliv Lund,
Ole Morten Seternes
m.fl.:
MiRNA expression profiling based on different high-throughput
platforms reveals surprising variations
2011
Anett Kristin Larsen,
Berit Bang,
Ole Morten Seternes
:
Proteases from seafood as activators of protease-activated receptor-2 in airway epithelial cells
UiT Norges arktiske universitet 2010
Merethe Larsen,
Berit Bang,
ole morten Seternes,
Anett K. Larsen
:
Protease-activated signal pathways in airway cells. Purified salmon trypsin activates nuclear factor kappa-B and induces interleukin-8 secretion in human airway epithelial cells (A549)
Allergy. European Journal of Allergy and Clinical Immunology 2007
Anett Kristin Larsen,
Merethe Larsen,
Ole Morten Seternes,
Berit Bang
:
Protease-activated signal pathways in airway cells. Purified salmon trypsin activates Nuclear factor kappa-B and induces interleukin-8 secretion in human airway epithelial cells (A549)
2007
ole morten Seternes
:
The atypical MAP kinases ERK3 and 4 defines novel signaling pathways
2006
ole morten Seternes
:
The atypical MAP kinases ERK3 and 4 defines novel signaling pathways
2006
Espen Åberg,
maria Perander,
Bjarne Herold Johansen,
Catherine Julien,
Sylvain Meloche,
Stephen M Keyse
m.fl.:
Regulation of MAPK-activated protein kinase 5 activity and subcellular localization by the atypical MAP kinase ERK4/MAPK4
2006
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