Trond Flægstad
Stillingsbeskrivelse
Professor i barnesykdommer
Swapnil Bhavsar,
Lotte Olsen,
Cecilie Løkke,
Jan Koster,
Trond Flægstad,
Christer Einvik
:
Hsa-miR-323a-3p functions as a tumor suppressor and targets STAT3 in neuroblastoma cells
Dan Hameiri-Bowen,
Louis-Marie Yindom,
Evgeniya Sovershaeva,
Tsitsi Bandason,
Justin Mayini,
Andrea M Rehman
m.fl.:
“The effect of 48-weeks azithromycin therapy on levels of soluble biomarkers associated with HIV-associated chronic lung disease”
Trym Thune Flygel,
Dan Hameiri-Bowen,
Victoria Simms,
Sarah Rowland-Jones,
Rashida Abbas Ferrand,
Tsitsi Bandason
m.fl.:
Exhaled nitric oxide is associated with inflammatory biomarkers and risk of acute respiratory exacerbations in children with HIV-associated chronic lung disease
Olga Krali,
Yanara Marincevic-Zuniga,
Gustav Arvidsson,
Anna Pia Enblad,
Anders Lundmark,
Shumaila Sayyab
m.fl.:
Multimodal classification of molecular subtypes in pediatric acute lymphoblastic leukemia
Karen Schow Jensen,
Trausti Oskarsson,
Päivi M. Lähteenmäki,
Trond Flægstad,
Ólafur Gísli Jónsson,
Petter Svenberg
m.fl.:
Temporal changes in incidence of relapse and outcome after relapse of childhood acute lymphoblastic leukemia over three decades; a Nordic population-based cohort study
Leukemia 2022 DOI
Dan Hameiri-Bowen,
Evgeniya Sovershaeva,
Trond Flaegstad,
Tore Jarl Gutteberg,
Lucky Gift Ngwira,
Victoria Simms
m.fl.:
Soluble biomarkers associated with chronic lung disease in older children and adolescents with perinatal HIV infection
AIDS (London) 2021 DOI
Niklas Stabell,
Maria Averina,
Trond Flægstad
:
Chronic iron deficiency and anaemia were highly prevalent in a population-based longitudinal study among adolescent girls
Silje Fjellgård Jørgensen,
Jochen Buechner,
Anders Eivind Myhre,
Eivind Galteland,
Signe Spetalen,
Mari Ann Kulseth
m.fl.:
A Nationwide Study of GATA2 Deficiency in Norway-the Majority of Patients Have Undergone Allo-HSCT
Johanne Uthus Hermansen,
Dorota Wojcik,
Nina Robinson,
Jens Pahnke,
Hans Kristian Haugland,
Ann-Helen Jamtøy
m.fl.:
The Norwegian childhood cancer biobank
Karen S. Jensen,
Trausti Oskarsson,
Päivi M. Lähteenmäki,
Trond Flægstad,
Kjeld Schmiegelow,
Peter Vedsted
m.fl.:
Detection mode of childhood acute lymphoblastic leukaemia relapse and its effect on survival: a Nordic population-based cohort study
British Journal of Haematology 2021 DOI
Zahra Haider,
Mattias Landfors,
Irina Golovleva,
Martin Erlanson,
Kjeld Schmiegelow,
Trond Flægstad
m.fl.:
DNA methylation and copy number variation profiling of T-cell lymphoblastic leukemia and lymphoma
Rashida A. Ferrand,
Grace McHugh,
Andrea M. Rehman,
Hilda A. Mujuru,
Victoria Simms,
Edith D. Majonga
m.fl.:
Effect of Once-Weekly Azithromycin vs Placebo in Children With HIV-Associated Chronic Lung Disease: The BREATHE Randomized Clinical Trial
Zahra Haider,
Pär larsson,
Mattias Landfors,
Linda Kohn,
Kjeld Schmiegelow,
Trond Flægstad
m.fl.:
An integrated transcriptome analysis in T-cell acute lymphoblastic leukemia links DNA methylation subgroups to dysregulated TAL1 and ANTP homeobox gene expression
Trym Thune Flygel,
Evgeniya Sovershaeva,
Shantelle Classen-Weitz,
Erik Hjerde,
Kilaza S. Mwaikono,
Jon Øyvind Odland
m.fl.:
Composition of Gut Microbiota of Children and Adolescents With Perinatal Human Immunodeficiency Virus Infection Taking Antiretroviral Therapy in Zimbabwe
Hildegunn Norbakken Granslo,
Elizabeth Aarag,
Eirin Esaiassen,
Lars Christophersen,
Peter Østrup Jensen,
Tom Eirik Mollnes
m.fl.:
The synthetic antimicrobial peptide LTX21 induces inflammatory responses in a human whole blood model and a murine peritoneum model
Evgeniya Sovershaeva,
Katharina Kranzer,
Grace McHugh,
Tsitsi Bandason,
Edith D. Majonga,
Omar S. Usmani
m.fl.:
History of tuberculosis is associated with lower exhaled nitric oxide levels in HIV-infected children
Ane Sofie Kokkvoll,
Sameline Grimsgaard,
Trond Flægstad,
Lars Bo Andersen,
Geoff Ball,
Tom Wilsgaard
m.fl.:
No additional long-term effect of group vs individual family intervention in the treatment of childhood obesity : A randomised trial
Peter Utnes,
Cecilie Løkke,
Trond Flægstad,
Christer Einvik
:
Clinically Relevant Biomarker Discovery in High-Risk Recurrent Neuroblastoma
Evgeniya Sovershaeva,
Tinei Shamu,
Tom Wilsgaard,
Tsitsi Bandason,
Trond Flægstad,
David Katzenstein
m.fl.:
Patterns of detectable viraemia among children and adults with HIV infection taking antiretroviral therapy in Zimbabwe
Ole Mikal Wormdal,
Trond Flægstad,
Tore Stokland
:
Treatment of two cases on the same day of intrathecal methotrexate overdose using cerebrospinal fluid exchange and intrathecal instillation of carboxypeptidase-G2
Pediatric Hematology & Oncology 2018 DOI
Roth Sarah Andrea,
Øyvind Holsbø Hald,
Steffen Fuchs,
Cecilie Løkke,
Ingvild Mikkola,
Trond Flægstad
m.fl.:
MicroRNA-193b-3p represses neuroblastoma cell growth via downregulation of Cyclin D1, MCL-1 and MYCN
Swapnil Parashram Bhavsar,
Cecilie Løkke,
Trond Flægstad,
Christer Einvik
:
Hsa-miR-376c-3p targets cyclin D1 and induces G1-cell cycle arrest in neuroblastoma cells
Kine Nordheim,
Ingunn Holmefoss Hovland,
Bjørn Erik Kristiansen,
Per Ivar Kaaresen,
Trond Flægstad
:
An epidemic of meningococcal disease in children in North Norweay in the 1970s and 1980s was dominated by a hypervirulent group B strain
Acta Paediatrica 2018 DOI
Øyvind Holsbø Hald,
Lotte Olsen,
Gabriel Gallo-Oller,
Lotta Helena Maria Elfman,
Cecilie Løkke,
Per Kogner
m.fl.:
Inhibitors of ribosome biogenesis repress the growth of MYCN-amplified neuroblastoma.
Magnus Borssén,
Jessica Nordlund,
Zahra Haider,
Mattias Landfors,
Pär Larsson,
Jukka Kanerva
m.fl.:
DNA methylation holds prognostic information in relapsed precursor B-cell acute lymphoblastic leukemia
Carmen Gonzalez-Martinez,
Katharina Kranzer,
Grace McHugh,
Elizabeth L. Corbett,
Hilda A. Mujuru,
Mark P Nicol
m.fl.:
Azithromycin versus placebo for the
treatment of HIV-associated chronic lung
disease in children and adolescents
(BREATHE trial): study protocol for a
randomised controlled trial
Sarah A Roth,
Erik Knutsen,
Tonje Fiskaa,
Peter Andree Utnes,
Swapnil Parashram Bhavsar,
Øyvind Hald
m.fl.:
Next generation sequencing of microRNAs from isogenic neuroblastoma cell lines isolated before and after treatment
Cancer Letters 2016 DOI
Jessica Nordlund,
Christopher L. Bäcklin,
Vasilios Zachariadis,
Lucia Cavelier,
Johan Dahlberg,
Ingegerd Öfverholm
m.fl.:
Dna methylation-based subtype prediction for pediatric acute lymphoblastic leukemia
Ane Sofie Kokkvoll,
Sameline Grimsgaard,
Silje Steinsbekk,
Trond Flægstad,
Inger Njølstad
:
Health in overweight children: 2-Year follow-up of Finnmark Activity School - A randomised trial
Bjørn Helge Haug,
Øyvind Hald,
Peter Utnes,
Sarah A Roth,
Cecilie Løkke,
Trond Flægstad
m.fl.:
Exosome-like extracellular vesicles from MYCN-amplified neuroblastoma cells contain oncogenic miRNAs
Anticancer Research 2015 SAMMENDRAG / ARKIV
Elizabeth Aarag,
Trond Flægstad,
Fatemeh Askarian,
Claus Klingenberg
:
Colonisation and interaction between S. epidermidis and S. aureus in the nose and throat of healthy adolescents.
European Journal of Clinical Microbiology and Infectious Diseases 2015 DOI
Jorunn Pauline Cavanagh,
Erik Hjerde,
Matthew T.G. Holden,
Tim Kahlke,
Claus Klingenberg,
Trond Flægstad
m.fl.:
Whole-genome sequencing reveals clonal expansion of multiresistant Staphylococcus heamolyticus in European hopsitals
Niklas Stabell,
Audun Stubhaug,
Trond Flægstad,
Emeran Mayer,
Bruce D. Naliboff,
Christopher Sivert Nielsen
:
Widespread hyperalgesia in adolescents with symptoms of irritable bowel syndrome: Results from a large population-based study
Niklas Stabell,
Trond Flægstad,
Audun Stubhaug,
Christopher Sivert Nielsen
:
Associations between abdominal pain symptom dimensions and depression among adolescents
Scandinavian Journal of Pain 2014 DOI
Elizabeth Aarag Fredheim,
Trond Flægstad,
Fatemeh Askarian,
Claus Klingenberg
:
Colonisation and interaction between S. epidermidis and S. aureus in the nose and throat of healthy adolescents
European Journal of Clinical Microbiology and Infectious Diseases 2014 DOI
Ane Sofie Kokkvoll,
Sameline Grimsgaard,
Rønnaug Ødegård,
Trond Flægstad,
Inger Njølstad
:
Single versus multiple-family intervention in childhood overweight - Finnmark Activity School: A randomised trial
Jessica Nordlund,
Christopher L. Bäcklin,
Per Wahlberg,
Stephan Busche,
Eva C. Berglund,
Maija-Leena Eloranta
m.fl.:
Genome-wide signatures of differential DNA methylation in pediatric acute lymphoblastic leukemia
Jorunn Pauline Cavanagh,
Hildegunn Norbakken Granslo,
Elizabeth Aarag,
L Christophersen,
Peter Østrup Jensen,
Kim Thomsen
m.fl.:
Efficacy of a synthetic antimicrobial peptidomimetic versus vancomycin in a Staphylococcus epidermidis device-related murine peritonitis model
Journal of Antimicrobial Chemotherapy 2013 DOI
Niklas Bernhard Stabell,
Audun Stubhaug,
Trond Flægstad,
Christopher Sivert Nielsen
:
Increased pain sensitivity among adults reporting irritable bowel syndrome symptoms in a large population-based study
Pain 2013 DOI
Hildegunn Norbakken Granslo,
Claus Klingenberg,
Elizabeth A. Fredheim,
Ganesh Acharya,
Tom Eirik Mollnes,
Trond Flægstad
:
Staphylococcus epidermidis biofilms induce lower complement activation in neonates as compared with adults
Pediatric Research 2013 DOI
Jorunn Pauline Cavanagh,
Claus Klingenberg,
Anne-Merethe Hanssen,
Elizabeth Aarag,
Patrice Francois,
Jaques Schrenzel
m.fl.:
Core genome conservation of Staphylococcus haemolyticus limits sequence based population structure analysis
Ane Sofie Kokkvoll,
Elisabeth Jeppesen,
Petur Benedikt Juliusson,
Trond Flægstad,
Inger Njølstad
:
High prevalence of overweight and obesity among 6-year-old children in Finnmark County, North Norway
Jørn Remi Henriksen,
Bjørn Helge Haug,
Jochen Büchner,
Ellen Tømte,
Cecilie Løkke,
Trond Flaegstad
m.fl.:
Conditional expression of retrovirally delivered anti-MYCN shRNA as an in vitro model system to study neuronal differentiation in MYCN-amplified neuroblastoma
Gunnar Lönnerholm,
Ingrid Thörn,
Christer Sundström,
Britt-Marie Frost,
Trond Flaegstad,
Mats Heyman
m.fl.:
In vitro cellular drug resistance adds prognostic information to other known risk-factors in childhood acute lymphoblastic leukemia
Leukemia Research 2011 DOI
Jochen Buechner,
Ellen Tømte,
Bjørn Helge Haug,
Jørn Remi Henriksen,
Cecilie Løkke,
Trond Flægstad
m.fl.:
Tumour-suppressor microRNAs let-7 and mir-101 target the proto-oncogene MYCN and inhibit cell proliferation in MYCN-amplified neuroblastoma
Bjørn Helge Haug,
Jørn Remi Henriksen,
Jochen Buechner,
Dirk Geerts,
Ellen Tømte,
Per Kogner
m.fl.:
MYCN-regulated miRNA-92 inhibits secretion of the tumor suppressor DICKKOPF-3 (DKK3) in neuroblastoma
Carcinogenesis 2011 DOI
Karen Jensen,
Trausti Oskarsson,
Päivi Lähteenmäki,
Trond Flægstad,
Kjeld Schmiegelow,
Peter Vedsted
m.fl.:
Doing less, accomplishing more for childhood ALL: response
British Journal of Haematology 2021 DOI
Ioannis Panagopoulos,
Marta Brunetti,
Margrethe Stoltenberg,
Rønnaug Strandabø,
Julie Staurseth,
Kristin Andersen
m.fl.:
Novel GTF2I-PDGFRB and IKZF1-TYW1 fusions in pediatric leukemia with normal karyotype
Hildegunn Norbakken Granslo,
Elizabeth Aarag,
Claus Andreas Klingenberg,
Claus Moser,
Eirin Esaiassen,
Jorunn Pauline Cavanagh
m.fl.:
The synthetic antimicrobial peptide LTX21 induces inflammatory responses in an in vivo mouse peritonitis model and an ex vivo human whole blood model
2017
E. G Fredheim,
Trond Flægstad,
Fatemeh Askarian,
C. Klingenberg
:
S. epidermidis and S. aureus in the nose and throat of healthy adolescents.
2014
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Forskningsinteresser
Kreft hos barn, spesielt neuroblastom og leukemic.
Infeksjoner hos barn, spesielt stafylokokkinfeksjoner og meningokokkinfeksjoner.
