Foto: Marit Helgerud
John Sigurd Mjøen Svendsen
Stillingsbeskrivelse
Professor, CSO Amicoat AS
Adam Hansson,
Eskil André Karlsen,
Wenche Gunvor B Stensen,
John Sigurd Mjøen Svendsen,
Mattias Berglin,
Anders Lundgren
:
Preventing E. coli Biofilm Formation with Antimicrobial Peptide-Functionalized Surface Coatings: Recognizing the Dependence on the Bacterial Binding Mode Using Live-Cell Microscopy
Adéla Melcrová,
Sourav Maity,
Josef Melcr,
Niels A. W. de Kok,
Mariella Gabler,
Jonne van der Eyden
m.fl.:
Lateral membrane organization as target of an antimicrobial peptidomimetic compound
Martin Jakubec,
Fredrik G. Rylandsholm,
Philip Rainsford,
Mitchell Silk,
Maxim Bril'kov,
Tone Kristoffersen
m.fl.:
Goldilocks Dilemma: LPS Works Both as the Initial Target and a Barrier for the Antimicrobial Action of Cationic AMPs on E. coli
Mattias Berglin,
Jorunn Pauline Cavanagh,
Josefin Seth Caous,
Balmukund Thakkar,
Jeddah Marie Vasquez,
Wenche Gunvor B Stensen
m.fl.:
Flexible and Biocompatible Antifouling Polyurethane Surfaces Incorporating Tethered Antimicrobial Peptides through Click Reactions
Philip Ben Rainsford,
Fredrik G. Rylandsholm,
Martin Jakubec,
Mitchell Silk,
Eric Juskewitz,
Johanna Ulrica Ericson
m.fl.:
Label-free measurement of antimicrobial peptide interactions with lipid vesicles and nanodiscs using microscale thermophoresis
Anne Sofie Laulund,
Franziska Angelika Schwartz,
Lars Christophersen,
Niels Høiby,
John Sigurd Mjøen Svendsen,
Wenche Gunvor Berg Stensen
m.fl.:
Lactoferricin-inspired peptide AMC-109 augments the effect of ciprofloxacin against Pseudomonas aeruginosa biofilm in chronic murine wounds
Bangfu Zhu,
Tom Parsons,
Wenche Gunvor Berg Stensen,
John Sigurd Mjøen Svendsen,
Anders Fugelli,
James W.L. Hodge
:
DYRK1a Inhibitor Mediated Rescue of Drosophila Models of Alzheimer’s Disease-Down Syndrome Phenotypes
Wenche Stensen,
Ulli Rothweiler,
Richard Alan Engh,
Melissa R. Stasko,
Ilya Bederman,
Alberto C. S. Costa
m.fl.:
Novel DYRK1A Inhibitor Rescues Learning and Memory Deficits in a Mouse Model of Down Syndrome
Eskil André Karlsen,
Wenche Stensen,
Eric Juskewitz,
Johan Svenson,
Mattias Berglin,
John Sigurd Mjøen Svendsen
:
Anti-Colonization Effect of Au Surfaces with Self-Assembled Molecular Monolayers Functionalized with Antimicrobial Peptides on S. epidermidis
Joakim Håkansson,
Jorunn Pauline Cavanagh,
Wenche Gunvor Berg Stensen,
Bjarte Mortensen,
John Sigurd Mjøen Svendsen,
Johan Svenson
:
In vitro and in vivo antibacterial properties of peptide AMC-109 impregnated wound dressings and gels
Journal of antibiotics (Tokyo. 1968) 2021 DOI
Worku Dinku,
Johan Isaksson,
Fredrik G. Rylandsholm,
Petr Bouř,
Eva Brichtova,
Sang Un Choi
m.fl.:
Anti-proliferative activity of a novel tricyclic triterpenoid acid from Commiphora africana resin against four human cancer cell lines
Jacobus Johannes Eksteen,
Dominik Ausbacher,
Terje Vasskog,
Øystein Rekdal,
John Sigurd Mjøen Svendsen
:
Selective intracellular delivery of thiolated cargo to tumor and neovasculature cells using histidine-rich peptides as vectors
John Sigurd Mjøen Svendsen,
Thomas M Grant,
David Rennison,
Margaret A. Brimble,
Johan Svenson
:
Very Short and Stable Lactoferricin-Derived Antimicrobial Peptides: Design Principles and Potential Uses
Accounts of Chemical Research 2019 DOI
Balmukund Thakkar,
John Sigurd Mjøen Svendsen,
Richard Alan Engh
:
Density Functional Studies on Secondary Amides: Role of Steric Factors in Cis/Trans Isomerization
Balmukund Thakkar,
John Sigurd Mjøen Svendsen,
Richard Alan Engh
:
Cis/Trans Isomerization in Secondary Amides: Reaction Paths, Nitrogen Inversion and Relevance to Peptidic Systems
Balmukund Thakkar,
Marte Albrigtsen,
John Sigurd Mjøen Svendsen,
Jeanette hammer Andersen,
Richard Alan Engh
:
Biofocussed chemoprospecting: An efficient approach for drug discovery
Wenche Stensen,
Rob Turner,
Marc Brown,
Nahid Kondori,
John Sigurd Mjøen Svendsen,
Johan Svenson
:
Short Cationic Antimicrobial Peptides Display Superior Antifungal Activities toward Candidiasis and Onychomycosis in Comparison with Terbinafine and Amorolfine
Molecular Pharmaceutics 2016 DOI
Jacobus Johannes Eksteen,
Dominik Ausbacher,
Jaione Simon-Santamaria,
Trine Stiberg,
Cristiane de Albuquerque Cavalcanti Jacobsen,
Imin Wushur
m.fl.:
Iterative design and in vivo evaluation of an oncolytic antilymphoma peptide
Journal of Medicinal Chemistry 2016 DOI
Ulli Rothweiler,
Wenche Stensen,
Bjørn Olav Brandsdal,
Johan Isaksson,
Frederick Alan Leeson,
Richard Alan Engh
m.fl.:
Probing the ATP-Binding Pocket of Protein Kinase DYRK1A with Benzothiazole Fragment Molecules
Journal of Medicinal Chemistry 2016 DOI
Bengt Erik Haug,
Ketil Andre Camilio,
liv tone Eliassen,
Wenche Stensen,
John Sigurd Mjøen Svendsen,
Kristel Berg
m.fl.:
Discovery of a 9-mer cationic peptide (LTX-315) as a potential first in class oncolytic peptide
Journal of Medicinal Chemistry 2016 DOI
Ulli Rothweiler,
Jonas Eriksson,
Wenche Stensen,
Frederick Alan Leeson,
Richard Alan Engh,
John Sigurd Svendsen
:
Luciferin and derivatives as a DYRK selective scaffold for the design of protein kinase inhibitors
European Journal of Medicinal Chemistry 2015 DOI
Annfrid Sivertsen,
Johan Isaksson,
Hanna-Kirsti S. Leiros,
Johan Svenson,
John Sigurd Svendsen,
Bjørn Olav Brandsdal
:
Synthetic cationic antimicrobial peptides bind with their hydrophobic parts to drug site II of human serum albumin
Olga Vladimirovna Gozhina,
John Sigurd Svendsen,
Tore Lejon
:
Synthesis and antimicrobial activity of α-aminoboronic-containing peptidomimetics
Journal of Peptide Science 2014 DOI
Rozenn Trepos,
Gunnar Cervin,
Claire Hellio,
Henrik Pavia Henrik,
Wenche Stensen,
Klara Stensvåg
m.fl.:
Antifouling compounds from the sub-arctic ascidian synoicum pulmonaria: Synoxazolidinones A and C, pulmonarins A and B, and synthetic analogues
Journal of natural products 2014 DOI
Taye B. Demissie,
Michal Repisky,
Stanislav Komorovsky,
Johan Isaksson,
John Sigurd Svendsen,
H Dodziuk
:
Four-component relativistic chemical shift calculations of halogenated organic compounds
Journal of Physical Organic Chemistry 2013 DOI
Annfrid Sivertsen,
Bjørn Olav Brandsdal,
John Sigurd Svendsen,
Jeanette hammer Andersen,
Johan Svenson
:
Short cationic antimicrobial peptides bind to human alpha-1 acid glycoprotein with no implications for the in vitro bioactivity
Journal of Molecular Recognition 2013 DOI
Alexey Sergeevich Gorovoy,
Olga Vladimirovna Gozhina,
John Sigurd Svendsen,
George V. Tetz,
Anna A. Domorad,
Victor V. Tetz
m.fl.:
Syntheses and anti-tubercular activity of β-substituted and α,β-disubstituted peptidyl β-aminoboronates and boronic acids
Journal of Peptide Science 2013 DOI
Alexey Sergeevich Gorovoy,
Olga Vladimirovna Gozhina,
John Sigurd Svendsen,
Anna A. Domorad,
Victor V. Tetz,
George V. Tetz
m.fl.:
Boron containing peptidomimetics – a novel class of selective anti-tubercular drugs
Chemical Biology and Drug Design (CB&DD) 2013 DOI
Xiaojun Li,
Kathrin Helen Hopmann,
Jana Hudecova,
Johan Isaksson,
Jana Novotná,
Wenche Stensen
m.fl.:
Determination of Absolute Configuration and Conformation of a Cyclic Dipeptide by NMR and Chiral Spectroscopic Methods
Journal of Physical Chemistry A 2013 DOI
Kathrin Helen Hopmann,
Jaroslav Šebestík,
Jana Novotná,
Wenche Stensen,
Marie Urbanová,
Johan Svenson
m.fl.:
Determining the Absolute Configuration of Two Marine Compounds Using Vibrational Chiroptical Spectroscopy
Journal of Organic Chemistry 2012 DOI
Xiaojun Li,
Kathrin Helen Hopmann,
Jana Hudecova,
Wenche Stensen,
Jana Novotná,
Marie Urbanová
m.fl.:
Absolute Configuration of a Cyclic Dipeptide Reflected in Vibrational Optical Activity: Ab Initio and Experimental Investigation
Journal of Physical Chemistry A 2012 DOI
Kine Østnes Hanssen,
Bruno Schuler,
Antony J. Williams,
Taye B. Demissie,
Espen Hansen,
Jeanette hammer Andersen
m.fl.:
A Combined Atomic Force Microscopy and Computational Approach for the Structural Elucidation of Breitfussin A and B: Highly Modified Halogenated Dipeptides from Thuiaria breitfussi
Angewandte Chemie International Edition 2012 DOI
Rasmus Tørnes Karstad,
Geir Villy Isaksen,
Evelien Wynendaele,
Yngve Guttormsen,
Bart De Spiegeleer,
Bjørn Olav Brandsdal
m.fl.:
Targeting the S1 and S3 Subsite of Trypsin with Unnatural Cationic Amino Acids Generates Antimicrobial Peptides with Potential for Oral Administration
Journal of Medicinal Chemistry 2012 DOI
Derk Avenarius,
John Sigurd Svendsen,
Dag Malm
:
Proton nuclear magnetic resonance spectroscopic detection of oligomannosidic n glycans in alpha-mannosidosis: a method of monitoring treatment
The Journal of Inherited Metabolic Disease (JIMD) 2011 DOI
Johan Isaksson,
Bjørn Olav Brandsdal,
Stig Olov Magnus Engqvist,
Gøril Eide Flaten,
John Sigurd Svendsen,
Wenche Stensen
:
A Synthetic Antimicrobial Peptidomimetic (LTX 109): Stereochemical Impact on Membrane Disruption
Journal of Medicinal Chemistry 2011 DOI
Gøril Eide Flaten,
Gabor Kottra,
Wenche Stensen,
Geir Villy Isaksen,
Rasmus Tørnes Karstad,
John Sigurd Svendsen
m.fl.:
In Vitro Characterization of Human Peptide Transporter hPEPT1 Interactions and Passive Permeation Studies of Short Cationic Antimicrobial Peptides
Journal of Medicinal Chemistry 2011 DOI
Johan Svenson,
V Vergote,
Rasmus Tørnes Karstad,
C Burvenich,
John Sigurd Svendsen,
B De Spiegeleer
:
Metabolic Fate of Lactoferricin-Based Antimicrobial Peptides: Effect of Truncation and Incorporation of Amino Acid Analogs on the In Vitro Metabolic Stability
Journal of Pharmacology and Experimental Therapeutics 2010 DOI
John Sigurd Mjøen Svendsen
:
Hva betyr antibiotikakrisen for kreftpasienter
2018
John Sigurd Mjøen Svendsen
:
Paneldebatt: Antibiotikaresistens og kreft
2018
John Sigurd Mjøen Svendsen
:
Panel: Are new antibiotics the solution to the AMR threat?
2018
Finn-Eirik Johansen,
Trygve Brautaset,
Marie Hjelmseth Aune,
Alexandra Patriksson,
Liv Eggset Falkenberg,
Rune Kleppe
m.fl.:
Centre for Digital Life Norway - Annual report 2017
2018 ARKIV
Claire Hellio,
Henrik Pavia,
Tor Haug,
Wenche Stensen,
Klara Stensvåg,
John Sigurd Svendsen
m.fl.:
Antifouling compounds from the sub-Arctic ascidian Synoicum pulmonaria
2014
Inger Greve Alsos,
Torbjørn Ekrem,
John Sigurd Svendsen
:
- Kan bidra til utviklingen av nye medisiner
13. mars 2014 FULLTEKST
Inger Greve Alsos,
Torbjørn Ekrem,
John Sigurd Svendsen
:
DNA fra planter og dyr kan gi kunnskap om sykdommer
13. mars 2014 FULLTEKST
Inger Greve Alsos,
Torbjørn Ekrem,
John Sigurd Svendsen
:
Lager digitalt oppslagsverk over alt liv på jorda
13. mars 2014 FULLTEKST
Balmukund Thakkar,
John Sigurd Mjøen Svendsen,
Richard Alan Engh
:
Design and Synthesis of diverse Piperazine-2,5-diones and their uncyclized analogues as potential kinase inhibitors
2013
Kine Ø. Hanssen,
Bruno Schuler,
Antony J. Williams,
Taye B. Demissie,
Espen Hansen,
Jeanette hammer Andersen
m.fl.:
Introducing Atomic Force Microscopy in Structure Elucidation
2013
Geir Villy Isaksen,
Johan Isaksson,
John Sigurd Svendsen,
Bjørn Olav Brandsdal
:
Structural studies of small cationic antimicrobial peptides by NMR and computer simulations have facilitated a refined pharmacophore model able to predict activity versus Staphylococcus aureus
2011
Geir Villy Isaksen,
Rasmus Tørnes Karstad,
Johan Mattias Isaksson,
Johan Svenson,
John Sigurd Svendsen,
Bjørn Olav Brandsdal
:
Structure of short cationic antimicrobial peptides and their interactions with membranes as revealed by MD simulations
2010
Johan Isaksson,
Gøril Eide Flaten,
Bjørn Olav Brandsdal,
John Sigurd Svendsen
:
Studies of Small Synthetic Anti-microbial Peptides by NMR and Molecular Modeling
2010
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