Kreft og kreftbehandling
Foto: Kjetil Rydland
Jeanette Hammer Andersen
Enhet: Norges fiskerihøgskole
marin bioprospektering, bioaktivitetstesting og identifisering av nye naturstoff som kan bli ny medisin
Espen Holst Hansen
Enhet: Norges fiskerihøgskole
Mitt ansvarsområde i Marbio er kjemisk karakterisering av bioaktive naturstoffer fra arktiske planter, dyr og mikroorganismer. Jeg jobber hovedsaklig med følgende teknikker:
- Massespektrometri (MS)
- Kromatografi
Terje Johansen
Enhet: Autophagy Research Group
Autofagi, celle signalering og genregulering med relevans for kreft,nevrodegenererende sykdommer og forsvar mot intracellulære infeksjoner.
Erik Knutsen
Enhet: Institutt for medisinsk biologi
I’m currently leading a single cell RNA-sequencing project with the aim of subclassifying breast cancer cell present in the lymph nodes for better personalized diagnosis and treatment.
The project will assess the transcriptional changes in breast cancer cells as they are subjected to the microenvironment of the lymph nodes, and will examine the impact of this new microenvironment on epithelial mesenchymal transition, cancer stem cells, and risk of metastasis, recurrence, and dormancy. The project combines the use of fresh patient samples, bioinformatics, and in vivo and in vitro models.
I have an ambition to better diagnosis for breast cancer patients to prevent overtreatment with serious side effects, to generate new basic knowledge on metastasis, and to find new targets for prevention of metastasis. I further want to tackle the problem of tumor dormancy, as this is one of the great challenges when it comes to relapse and metastasis.
I believe solving the problems of metastasis and tumor dormancy can only be reached by a strong collaboration between clinicians/ oncologists, bioinformaticians, and molecular biologists, and I have therefore established such collaborations locally, nationally, and internationally.
Lill-Tove Rasmussen Busund
Enhet: Institutt for medisinsk biologi
Biomarkører i kreftsvulster og blod som kan gi informasjon om framtidig kreftsykdom, hvilken type kreftsykdom, prognose av kreftsykdom og hvilken behandling som kan gi effekt.
Ole Morten Seternes
Enhet: Cellesignalering og målrettet terapi
Arne O. Smalås
Enhet: Fakultet for naturvitenskap og teknologi
- Makromolekylers struktur og funksjon
- Det molekylære opphav til enzymers kuldeadaptasjon
- Utvikling av enzymer for anvendelse
- Bioprospektering
Elisabete Weiderpass Vainio
Enhet: Institutt for samfunnsmedisin
My research interest is mainly on etiological factors in female cancers. In the project "Women's Lifestyle and Health" we try to identify potentially modifiable risk factors for cancers of the breast, ovarian, endometrium, colorectum and skin, as well as for cardiovascular diseases (myocardial infarction, stroke) and overall mortality. I am also interested in factors affecting cancer survival. I coordinate the Ugandan collaboration on infections diseases and cancer, where we are studying the role of infectious agents such as HIV, human papilloma viruses (HPV), and EBV in the etiology of cancer of the cervix uteri, conjunctiva, and Burkitt’s Lymphoma, hormones and cancer, cancer research in developing countries.
- Etiological and prognostic cancer research
- Cancer in low-income countries
- Infections and cancer
- Lifestyle and cancer
- Women and cancer
