Bilde av Flægstad, Trond
Bilde av Flægstad, Trond
Professor i barnesykdommer Msc i sykepleie og videreutd. ABIKO tfl001@uit.no 0047 92455047

Trond Flægstad


Stillingsbeskrivelse

Professor i barnesykdommer


  • Dan Hameiri-Bowen, Louis-Marie Yindom, Evgeniya Sovershaeva, Tsitsi Bandason, Justin Mayini, Andrea M Rehman m.fl.:
    “The effect of 48-weeks azithromycin therapy on levels of soluble biomarkers associated with HIV-associated chronic lung disease”
    International Immunopharmacology 2023 ARKIV / DOI
  • Trym Thune Flygel, Dan Hameiri-Bowen, Victoria Simms, Sarah Rowland-Jones, Rashida Abbas Ferrand, Tsitsi Bandason m.fl.:
    Exhaled nitric oxide is associated with inflammatory biomarkers and risk of acute respiratory exacerbations in children with HIV-associated chronic lung disease
    HIV Medicine 2023 ARKIV / DOI
  • Swapnil Bhavsar, Lotte Olsen, Cecilie Løkke, Jan Koster, Trond Flægstad, Christer Einvik :
    Hsa-miR-323a-3p functions as a tumor suppressor and targets STAT3 in neuroblastoma cells
    Frontiers in pediatrics 2023 ARKIV / DOI
  • Olga Krali, Yanara Marincevic-Zuniga, Gustav Arvidsson, Anna Pia Enblad, Anders Lundmark, Shumaila Sayyab m.fl.:
    Multimodal classification of molecular subtypes in pediatric acute lymphoblastic leukemia
    NPJ precision oncology 2023 ARKIV / DOI
  • Karen Schow Jensen, Trausti Oskarsson, Päivi M. Lähteenmäki, Trond Flægstad, Ólafur Gísli Jónsson, Petter Svenberg m.fl.:
    Temporal changes in incidence of relapse and outcome after relapse of childhood acute lymphoblastic leukemia over three decades; a Nordic population-based cohort study
    Leukemia 2022 DOI
  • Dan Hameiri-Bowen, Evgeniya Sovershaeva, Trond Flaegstad, Tore Jarl Gutteberg, Lucky Gift Ngwira, Victoria Simms m.fl.:
    Soluble biomarkers associated with chronic lung disease in older children and adolescents with perinatal HIV infection
    AIDS (London) 2021 DOI
  • Niklas Stabell, Maria Averina, Trond Flægstad :
    Chronic iron deficiency and anaemia were highly prevalent in a population-based longitudinal study among adolescent girls
    Acta Paediatrica 2021 ARKIV / DOI
  • Silje Fjellgård Jørgensen, Jochen Buechner, Anders Eivind Myhre, Eivind Galteland, Signe Spetalen, Mari Ann Kulseth m.fl.:
    A Nationwide Study of GATA2 Deficiency in Norway-the Majority of Patients Have Undergone Allo-HSCT
    Journal of Clinical Immunology 2021 ARKIV / DOI
  • Johanne Uthus Hermansen, Dorota Wojcik, Nina Robinson, Jens Pahnke, Hans Kristian Haugland, Ann-Helen Jamtøy m.fl.:
    The Norwegian childhood cancer biobank
    Cancer Reports 2021 ARKIV / DOI
  • Karen S. Jensen, Trausti Oskarsson, Päivi M. Lähteenmäki, Trond Flægstad, Kjeld Schmiegelow, Peter Vedsted m.fl.:
    Detection mode of childhood acute lymphoblastic leukaemia relapse and its effect on survival: a Nordic population-based cohort study
    British Journal of Haematology 2021 DOI
  • Zahra Haider, Mattias Landfors, Irina Golovleva, Martin Erlanson, Kjeld Schmiegelow, Trond Flægstad m.fl.:
    DNA methylation and copy number variation profiling of T-cell lymphoblastic leukemia and lymphoma
    Blood Cancer Journal 2020 ARKIV / DOI
  • Rashida A. Ferrand, Grace McHugh, Andrea M. Rehman, Hilda A. Mujuru, Victoria Simms, Edith D. Majonga m.fl.:
    Effect of Once-Weekly Azithromycin vs Placebo in Children With HIV-Associated Chronic Lung Disease: The BREATHE Randomized Clinical Trial
    JAMA Network Open 2020 ARKIV / DOI
  • Zahra Haider, Pär larsson, Mattias Landfors, Linda Kohn, Kjeld Schmiegelow, Trond Flægstad m.fl.:
    An integrated transcriptome analysis in T-cell acute lymphoblastic leukemia links DNA methylation subgroups to dysregulated TAL1 and ANTP homeobox gene expression
    Cancer Medicine 2019 ARKIV / DOI
  • Trym Thune Flygel, Evgeniya Sovershaeva, Shantelle Classen-Weitz, Erik Hjerde, Kilaza S. Mwaikono, Jon Øyvind Odland m.fl.:
    Composition of Gut Microbiota of Children and Adolescents With Perinatal Human Immunodeficiency Virus Infection Taking Antiretroviral Therapy in Zimbabwe
    Journal of Infectious Diseases 2019 ARKIV / DOI
  • Hildegunn Norbakken Granslo, Elizabeth Aarag, Eirin Esaiassen, Lars Christophersen, Peter Østrup Jensen, Tom Eirik Mollnes m.fl.:
    The synthetic antimicrobial peptide LTX21 induces inflammatory responses in a human whole blood model and a murine peritoneum model
    APMIS - Journal of Pathologiy, Microbiology and Immunology 2019 ARKIV / DOI
  • Evgeniya Sovershaeva, Katharina Kranzer, Grace McHugh, Tsitsi Bandason, Edith D. Majonga, Omar S. Usmani m.fl.:
    History of tuberculosis is associated with lower exhaled nitric oxide levels in HIV-infected children
    AIDS (London) 2019 ARKIV / DOI
  • Ane Sofie Kokkvoll, Sameline Grimsgaard, Trond Flægstad, Lars Bo Andersen, Geoff Ball, Tom Wilsgaard m.fl.:
    No additional long-term effect of group vs individual family intervention in the treatment of childhood obesity : A randomised trial
    Acta Paediatrica 2019 ARKIV / DOI
  • Peter Utnes, Cecilie Løkke, Trond Flægstad, Christer Einvik :
    Clinically Relevant Biomarker Discovery in High-Risk Recurrent Neuroblastoma
    Cancer Informatics 2019 ARKIV / DOI
  • Evgeniya Sovershaeva, Tinei Shamu, Tom Wilsgaard, Tsitsi Bandason, Trond Flægstad, David Katzenstein m.fl.:
    Patterns of detectable viraemia among children and adults with HIV infection taking antiretroviral therapy in Zimbabwe
    International Journal of Infectious Diseases 2018 ARKIV / DOI
  • Ole Mikal Wormdal, Trond Flægstad, Tore Stokland :
    Treatment of two cases on the same day of intrathecal methotrexate overdose using cerebrospinal fluid exchange and intrathecal instillation of carboxypeptidase-G2
    Pediatric Hematology & Oncology 2018 DOI
  • Roth Sarah Andrea, Øyvind Holsbø Hald, Steffen Fuchs, Cecilie Løkke, Ingvild Mikkola, Trond Flægstad m.fl.:
    MicroRNA-193b-3p represses neuroblastoma cell growth via downregulation of Cyclin D1, MCL-1 and MYCN
    OncoTarget 2018 ARKIV / DOI
  • Swapnil Parashram Bhavsar, Cecilie Løkke, Trond Flægstad, Christer Einvik :
    Hsa-miR-376c-3p targets cyclin D1 and induces G1-cell cycle arrest in neuroblastoma cells
    Oncology Letters 2018 ARKIV / DOI
  • Kine Nordheim, Ingunn Holmefoss Hovland, Bjørn Erik Kristiansen, Per Ivar Kaaresen, Trond Flægstad :
    An epidemic of meningococcal disease in children in North Norweay in the 1970s and 1980s was dominated by a hypervirulent group B strain
    Acta Paediatrica 2018 DOI
  • Øyvind Holsbø Hald, Lotte Olsen, Gabriel Gallo-Oller, Lotta Helena Maria Elfman, Cecilie Løkke, Per Kogner m.fl.:
    Inhibitors of ribosome biogenesis repress the growth of MYCN-amplified neuroblastoma.
    Oncogene 2018 ARKIV / DOI
  • Magnus Borssén, Jessica Nordlund, Zahra Haider, Mattias Landfors, Pär Larsson, Jukka Kanerva m.fl.:
    DNA methylation holds prognostic information in relapsed precursor B-cell acute lymphoblastic leukemia
    Clinical Epigenetics 2018 ARKIV / DOI
  • Carmen Gonzalez-Martinez, Katharina Kranzer, Grace McHugh, Elizabeth L. Corbett, Hilda A. Mujuru, Mark P Nicol m.fl.:
    Azithromycin versus placebo for the treatment of HIV-associated chronic lung disease in children and adolescents (BREATHE trial): study protocol for a randomised controlled trial
    Trials 2017 ARKIV / DOI
  • Sarah A Roth, Erik Knutsen, Tonje Fiskaa, Peter Andree Utnes, Swapnil Parashram Bhavsar, Øyvind Hald m.fl.:
    Next generation sequencing of microRNAs from isogenic neuroblastoma cell lines isolated before and after treatment
    Cancer Letters 2016 DOI
  • Jessica Nordlund, Christopher L. Bäcklin, Vasilios Zachariadis, Lucia Cavelier, Johan Dahlberg, Ingegerd Öfverholm m.fl.:
    Dna methylation-based subtype prediction for pediatric acute lymphoblastic leukemia
    Clinical Epigenetics 2015 ARKIV / DOI
  • Ane Sofie Kokkvoll, Sameline Grimsgaard, Silje Steinsbekk, Trond Flægstad, Inger Njølstad :
    Health in overweight children: 2-Year follow-up of Finnmark Activity School - A randomised trial
    Archives of Disease in Childhood 20. november 2014 ARKIV / DOI
  • Bjørn Helge Haug, Øyvind Hald, Peter Utnes, Sarah A Roth, Cecilie Løkke, Trond Flægstad m.fl.:
    Exosome-like extracellular vesicles from MYCN-amplified neuroblastoma cells contain oncogenic miRNAs
    Anticancer Research 2015 SAMMENDRAG / ARKIV
  • Elizabeth Aarag, Trond Flægstad, Fatemeh Askarian, Claus Klingenberg :
    Colonisation and interaction between S. epidermidis and S. aureus in the nose and throat of healthy adolescents.
    European Journal of Clinical Microbiology and Infectious Diseases 2015 DOI
  • Jorunn Pauline Cavanagh, Erik Hjerde, Matthew T.G. Holden, Tim Kahlke, Claus Klingenberg, Trond Flægstad m.fl.:
    Whole-genome sequencing reveals clonal expansion of multiresistant Staphylococcus heamolyticus in European hopsitals
    Journal of Antimicrobial Chemotherapy 2014 ARKIV / DOI
  • Niklas Stabell, Audun Stubhaug, Trond Flægstad, Emeran Mayer, Bruce D. Naliboff, Christopher Sivert Nielsen :
    Widespread hyperalgesia in adolescents with symptoms of irritable bowel syndrome: Results from a large population-based study
    Journal of Pain 2014 ARKIV / DOI
  • Niklas Stabell, Trond Flægstad, Audun Stubhaug, Christopher Sivert Nielsen :
    Associations between abdominal pain symptom dimensions and depression among adolescents
    Scandinavian Journal of Pain 2014 DOI
  • Elizabeth Aarag Fredheim, Trond Flægstad, Fatemeh Askarian, Claus Klingenberg :
    Colonisation and interaction between S. epidermidis and S. aureus in the nose and throat of healthy adolescents
    European Journal of Clinical Microbiology and Infectious Diseases 2014 DOI
  • Ane Sofie Kokkvoll, Sameline Grimsgaard, Rønnaug Ødegård, Trond Flægstad, Inger Njølstad :
    Single versus multiple-family intervention in childhood overweight - Finnmark Activity School: A randomised trial
    Archives of Disease in Childhood 2014 ARKIV / DOI
  • Jessica Nordlund, Christopher L. Bäcklin, Per Wahlberg, Stephan Busche, Eva C. Berglund, Maija-Leena Eloranta m.fl.:
    Genome-wide signatures of differential DNA methylation in pediatric acute lymphoblastic leukemia
    Genome Biology 2013 ARKIV / DOI
  • Jorunn Pauline Cavanagh, Hildegunn Norbakken Granslo, Elizabeth Aarag, L Christophersen, Peter Østrup Jensen, Kim Thomsen m.fl.:
    Efficacy of a synthetic antimicrobial peptidomimetic versus vancomycin in a Staphylococcus epidermidis device-related murine peritonitis model
    Journal of Antimicrobial Chemotherapy 2013 DOI
  • Niklas Bernhard Stabell, Audun Stubhaug, Trond Flægstad, Christopher Sivert Nielsen :
    Increased pain sensitivity among adults reporting irritable bowel syndrome symptoms in a large population-based study
    Pain 2013 DOI
  • Hildegunn Norbakken Granslo, Claus Klingenberg, Elizabeth A. Fredheim, Ganesh Acharya, Tom Eirik Mollnes, Trond Flægstad :
    Staphylococcus epidermidis biofilms induce lower complement activation in neonates as compared with adults
    Pediatric Research 2013 DOI
  • Jorunn Pauline Cavanagh, Claus Klingenberg, Anne-Merethe Hanssen, Elizabeth Aarag, Patrice Francois, Jaques Schrenzel m.fl.:
    Core genome conservation of Staphylococcus haemolyticus limits sequence based population structure analysis
    Journal of Microbiological Methods 2012 ARKIV / DOI
  • Ane Sofie Kokkvoll, Elisabeth Jeppesen, Petur Benedikt Juliusson, Trond Flægstad, Inger Njølstad :
    High prevalence of overweight and obesity among 6-year-old children in Finnmark County, North Norway
    Acta Paediatrica 2012 ARKIV / DOI
  • Jørn Remi Henriksen, Bjørn Helge Haug, Jochen Büchner, Ellen Tømte, Cecilie Løkke, Trond Flaegstad m.fl.:
    Conditional expression of retrovirally delivered anti-MYCN shRNA as an in vitro model system to study neuronal differentiation in MYCN-amplified neuroblastoma
    BMC Developmental Biology 2011 FULLTEKST / ARKIV / DOI
  • Gunnar Lönnerholm, Ingrid Thörn, Christer Sundström, Britt-Marie Frost, Trond Flaegstad, Mats Heyman m.fl.:
    In vitro cellular drug resistance adds prognostic information to other known risk-factors in childhood acute lymphoblastic leukemia
    Leukemia Research 2011 DOI
  • Jochen Buechner, Ellen Tømte, Bjørn Helge Haug, Jørn Remi Henriksen, Cecilie Løkke, Trond Flægstad m.fl.:
    Tumour-suppressor microRNAs let-7 and mir-101 target the proto-oncogene MYCN and inhibit cell proliferation in MYCN-amplified neuroblastoma
    British Journal of Cancer 2011 ARKIV / DOI
  • Bjørn Helge Haug, Jørn Remi Henriksen, Jochen Buechner, Dirk Geerts, Ellen Tømte, Per Kogner m.fl.:
    MYCN-regulated miRNA-92 inhibits secretion of the tumor suppressor DICKKOPF-3 (DKK3) in neuroblastoma
    Carcinogenesis 2011 DOI
  • Karen Jensen, Trausti Oskarsson, Päivi Lähteenmäki, Trond Flægstad, Kjeld Schmiegelow, Peter Vedsted m.fl.:
    Doing less, accomplishing more for childhood ALL: response
    British Journal of Haematology 2021 DOI
  • Ioannis Panagopoulos, Marta Brunetti, Margrethe Stoltenberg, Rønnaug Strandabø, Julie Staurseth, Kristin Andersen m.fl.:
    Novel GTF2I-PDGFRB and IKZF1-TYW1 fusions in pediatric leukemia with normal karyotype
    Experimental Hematology & Oncology 2019 ARKIV / DOI
  • Hildegunn Norbakken Granslo, Elizabeth Aarag, Claus Andreas Klingenberg, Claus Moser, Eirin Esaiassen, Jorunn Pauline Cavanagh m.fl.:
    The synthetic antimicrobial peptide LTX21 induces inflammatory responses in an in vivo mouse peritonitis model and an ex vivo human whole blood model
    2017
  • E. G Fredheim, Trond Flægstad, Fatemeh Askarian, C. Klingenberg :
    S. epidermidis and S. aureus in the nose and throat of healthy adolescents.
    2014

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    Forskningsinteresser

    Kreft hos barn, spesielt neuroblastom og leukemic.

    Infeksjoner hos barn, spesielt stafylokokkinfeksjoner og meningokokkinfeksjoner.