
Foto: Bjørn-Kåre Iversen
Rinaldo, Christine Hanssen
Professor II
Stillingsbeskrivelse
Forskning, undervisning og veiledning i virologi
Kirsten Midttun Gravningen,
Stian Henriksen,
Olav Hungnes,
Kristian Svendsen,
Emily Ann Macdonald,
Henrik Schirmer,
Kathrine Stene-Johansen,
Gunnar Skov Simonsen,
Oliver Kacelnik,
Petter Elstrøm,
Karoline Bragstad,
Christine Hanssen Rinaldo:
Risk factors, immune response and whole‐genome sequencing of SARS‐CoV‐2 in a cruise ship outbreak in Norway
International Journal of Infectious Diseases 2022 Ekstern lenke
Christine Hanssen Rinaldo,
Ingebjørg Helena Nymo,
Javier Sanchez Romano,
Eva Marie Breines,
Francisco Javier Ancin Murguzur,
Morten Tryland:
Serological evidence of hepatitis e virus infection in semi-domesticated eurasian tundra reindeer (Rangifer tarandus tarandus) in norway
Pathogens 2021 Ekstern lenke
Stian Henriksen,
Christine Hanssen Rinaldo:
Does the Evidence Support the Existence of the Simian Polyomavirus SV40 Vp4 Viroporin?
mSphere 2020 Ekstern lenke
Julia Manzetti,
Fabian H. Weissbach,
Fabrice E. Graf,
Gunhild Unterstab,
Marion Wernli,
Helmut Hopfer,
Cinthia B. Drachenberg,
Christine Hanssen Rinaldo,
Hans H. Hirsch:
BK polyomavirus evades innate immune sensing by disrupting the mitochondrial network and promotes mitophagy
iScience 10. juni 2020 Ekstern lenke
Irene Beate Olsøy,
Stian Henriksen,
Fabian H. Weissbach,
Marthe Larsen,
Karoline Borgen,
Florence Abravanel,
Nassim Kamar,
Eyvind Jakob Paulssen,
Hans H. Hirsch,
Christine Hanssen Rinaldo:
Seroprevalence of hepatitis E virus (HEV) in a general adult population
in Northern Norway: the Tromsø study
Medical Microbiology and Immmunology 2019 Ekstern lenke
Simone Cesaro,
Tina Dalianis,
Christine Hanssen Rinaldo,
Minna Koskenvuo,
Anna Pegoraro,
Hermann Einsele,
Catherine Cordonnier,
Hans H. Hirsch:
ECIL guidelines for the prevention, diagnosis and treatment of BK polyomavirus-associated haemorrhagic cystitis in haematopoietic stem cell transplant recipients
Journal of Antimicrobial Chemotherapy 2018 Ekstern lenke
Karl Bjørnar Alstadhaug,
Kjell-Morten Myhr,
Christine Hanssen Rinaldo:
Progredierende multifokal leukoencefalopati
Tidsskrift for Den norske legeforening 12. desember 2017 Ekstern lenke
Stian Henriksen,
Christian Mittelholzer,
Rainer Gosert,
Hans H Hirsch,
Christine Hanssen Rinaldo:
Human BK polyomavirus plasmid pBKV (34-2) (Dunlop) contains mutations not found in the originally published sequences
Microbiology Resource Announcements (MRA) 2016 Ekstern lenke
John C. Papadimitriou,
Parmjeet Singh Randhawa,
Christine Hanssen Rinaldo,
Cinithia B. Drachenberg,
Borislav A. Alexiev,
H. H. Hirsch:
BK polyomavirus infection and renourinary tumorigenesis
American Journal of Transplantation 2016 Ekstern lenke
Stian Henriksen,
Terkel Hansen,
Jack-Ansgar Bruun,
Christine Hanssen Rinaldo:
The Presumed Polyomavirus Viroporin VP4 of Simian Virus 40 or
Human BK Polyomavirus Is Not Required for Viral Progeny Release
Journal of Virology 2016 Ekstern lenke
Garth Daryl Tylden,
Hans H. Hirsch,
Christine Hanssen Rinaldo:
Brincidofovir (CMX001) inhibits BK polyomavirus replication in primary human urothelial cells
Antimicrobial Agents and Chemotherapy 2015 Ekstern lenke
Stian Henriksen,
Garth Daryl Tylden,
Alexis Dumoulin,
Sharma Biswa Nath,
Hans H. Hirsch,
Christine Hanssen Rinaldo:
The human fetal glial cell line SVG p12 contains infectious BK polyomavirus
Journal of Virology 2014 Ekstern lenke
Jaione Simon-Santamaria,
Christine Hanssen Rinaldo,
Piotr Kardas,
Ruomei Li,
Ivana Malovic,
kjetil helge Elvevold,
Peter Anthony McCourt,
Bård Smedsrød,
Hans H. Hirsch,
Karen Kristine Sørensen:
Efficient uptake of blood-borne BK and JC polyomavirus-like particles in endothelial cells of liver sinusoids and renal vasa recta
PLOS ONE 2014 Ekstern lenke
Biswa Nath Sharma,
Manfred Marschall,
Christine Hanssen Rinaldo:
Antiviral effects of artesunate on JC polyomavirus replication in COS-7 Cells
Antimicrobial Agents and Chemotherapy 2014 Ekstern lenke
HH Hirsch,
N Babel,
P Comoli,
V Friman,
F Ginevri,
AG Jardine,
I Lautenschlager,
Christophe M. Legendre,
Karsten Midtvedt,
P Munoz,
P Randhawa,
Christine Hanssen Rinaldo,
A Wieszek:
European perspective on human polyomavirus infection, replication and disease in solid organ transplantation.
Clinical Microbiology and Infection (CMI) 2014 Ekstern lenke
Biswa Nath Sharma,
Manfred Marschall,
Stian Henriksen,
Christine H Rinaldo:
Antiviral effects of artesunate on polyomavirus BK replication in primary human kidney cells
Antimicrobial Agents and Chemotherapy 2014 Ekstern lenke
Karl Bjørnar Alstadhaug,
Thérèse Croughs,
Stian Henriksen,
Céline Leboeuf,
Irini Sereti,
Hans H. Hirsch,
Christine Hanssen Rinaldo:
Treatment of progressive multifocal leukoencephalopathy with interleukin 7
JAMA Neurology 2014 Ekstern lenke
Christine H Rinaldo,
Garth Daryl Tylden,
Biswa Nath Sharma:
The human polyomavirus BK (BKPyV): virological background and clinical implications
APMIS - Journal of Pathologiy, Microbiology and Immunology 2013 Ekstern lenke
Ruomei Li,
Biswa Nath Sharma,
Stig Linder,
Tore Jarl Gutteberg,
Hans H. Hirsch,
Christine H Rinaldo:
Characteristics of polyomavirus BK (BKPyV) infection in primary human urothelial cells
Virology 2013 Ekstern lenke
Rainer Gosert,
Christine H Rinaldo,
Marion Wernli,
Eugene O. Major,
Hans H. Hirsch:
CMX001 (1-O-Hexadecyloxypropyl-Cidofovir) Inhibits Polyomavirus JC Replication in Human Brain Progenitor-Derived Astrocytes
Antimicrobial Agents and Chemotherapy 2011 Ekstern lenke
Biswa Nath Sharma,
Ruomei Li,
Eva Bernhoff,
Tore Jarl Gutteberg,
Christine H Rinaldo:
Fluoroquinolones inhibit human polyomavirus BK (BKV) replication in primary human kidney cells
Antiviral Research 2011 Ekstern lenke
Christiane Beckmann,
Alexis Dumoulin,
Christine H Rinaldo,
Hans H. Hirsch:
Comparison of a UL111a Real-time PCR and pp65 Antigenemia for the Detection of Cytomegalovirus
Journal of Medical Virology 2011 Ekstern lenke
Gunhild Unterstab,
Rainer Gosert,
David Leuenberger,
Pascal Lorentz,
Christine H Rinaldo,
Hans H. Hirsch:
The polyomavirus BK agnoprotein co-localizes with lipid droplets
Virology 2010 Ekstern lenke
Halvor Næss,
Solveig B Glad,
Anette Storstein,
Christine H Rinaldo,
Sverre Mørk,
Kjell-Morten Myhr,
Hans Hirsch:
Progressive multifocal leucoencephalopathy in an immunocompetent patient with favourable outcome. A case report
BMC Neurology 2010 Ekstern lenke
Christine H Rinaldo,
Rainer Gosert,
Eva Bernhoff,
Solrun Finstad,
Hans H. Hirsch:
1-O-Hexadecyloxypropyl Cidofovir (CMX001) Effectively Inhibits Polyomavirus BK Replication in Primary Human Renal Tubular Epithelial Cells
Antimicrobial Agents and Chemotherapy 2010 Ekstern lenke
Eva Bernhoff,
Garth Daryl Tylden,
Lars Jøran Kjerpeseth,
Tore Jarl Gutteberg,
Hans H. Hirsch,
Christine H Rinaldo:
Leflunomide Inhibition of BK Virus Replication in Renal Tubular Epithelial Cells
Journal of Virology 2010 Ekstern lenke
Marit Renee Myhre,
Gunn-Hege Olsen,
Rainer Gosert,
Hans H. Hirsch,
Christine H Rinaldo:
Clinical polyomavirus BK variants with agnogene deletion are non-functional but rescued by trans-complementation
Virology 2010 Ekstern lenke
gunn-hege Olsen,
Hans H. Hirsch,
christine h Rinaldo:
Functional Analysis of Polyomavirus BK Non-Coding Control Region Quasispecies From Kidney Transplant Recipients
Journal of Medical Virology 2009 Ekstern lenke
Clemens Furnes,
Øyvind Kileng,
Christine Hanssen Rinaldo,
Marit Seppola,
Ingvill Jensen,
Børre Robertsen:
Atlantic cod (Gadus morhua L.) possesses three homologues of ISG15 with different expression kinetics and conjugation properties
Developmental and Comparative Immunology 2009 Ekstern lenke
Eva Bernhoff,
tore jarl Gutteberg,
Kjersti Sandvik,
Hans H. Hirsch,
christine h Rinaldo:
Cidofovir inhibits polyomavirus BK replication in human renal tubular cells downstream of viral early gene expression
American Journal of Transplantation 2008 Ekstern lenke
Bjørn Grinde,
Marc Gayorfar,
Christine H. Rinaldo:
Impact of a polyomavirus (BKV) infection on mRNA expression in human endothelial cells
Virus Research 2007 Ekstern lenke
Gunn-Hege Olsen,
Andresen Per Arne,
Hilde Tveitan Hilmarsen,
Ola Bjørang,
Helge Scott,
Karsten Midtvedt,
Christine H Rinaldo:
Genetic variability in BK virus regulatory regions in urine and kidney biopsies from renal-transplant patients
Journal of Medical Virology 2006
Christine H Rinaldo,
Hilde Hansen,
Terje I Traavik:
Human endothelial cells allow passage of an archetypal BK virus (BKV) strain - a tool for cultivation and functional studies of natural BKV strains
Archives of Virology 2005
A Jul-Larsen,
Åsne Jul-Larsen,
T Visted,
BO Karlsen,
Christine H Rinaldo,
R Bjerkvig,
PE Lonning,
Per Eystein Lønning,
SO Boe,
Stig Ove Bøe:
PML-nuclear bodies accumulate DNA in response to polyomavirus BK and simian virus 40 replication
Experimental Cell Research 2004
christine h Rinaldo,
marit renee Myhre,
Hilde Alstad,
Ø Nilsen,
Terje Traavik:
BK virus transiently transforms and persistenly infects cultured human osteosarcoma cells
Virus Research 2003
Elias Myrvoll Lorentzen,
Stian Henriksen,
Amandeep Kaur,
Grete Anette Birkeland Kro,
Clara Louise Hammarström,
Hans H Hirsch,
Karsten Midtvedt,
Christine Hanssen Rinaldo:
Early fulminant BK polyomavirus-associated nephropathy in two kidney transplant patients with low neutralizing antibody titers receiving allografts from the same donor
Virology Journal 2020 Ekstern lenke
Christine Hanssen Rinaldo:
24 spørsmål og svar: Dette vet ekspertene om coronavaksine.
25. mars 2020
Karl Bjørnar Alstadhaug,
Christine Hanssen Rinaldo,
Liv T. N. Osnes,
Irini Sereti,
Hilde Karen Ofte:
Progressive multifocal leukoencephalopathy treated with interleukin-7
Clinical Infection in Practice 2020 Ekstern lenke
Christine Hanssen Rinaldo:
Kan det komme en ny bølge med coronavirus? Forskerne svarer.
26. mars 2020
Christine Hanssen Rinaldo:
SARS-CoV-2 mutasjoner
24. oktober 2020
Stian Henriksen,
Øyvind Trydal,
Sten-Eigil Sigurdsen,
Garth Daryl Tylden,
Christine Hanssen Rinaldo:
Antistoffrespons hos en familie med covid-19
Tidsskrift for Den norske legeforening 2020 Ekstern lenke
Christine Hanssen Rinaldo:
4 scenarioer: Slik slutter pandemien.
14. april 2020
Christine Hanssen Rinaldo:
Her smittes friske i jakten på vaksine
21. mars 2020
Christine Hanssen Rinaldo:
Coronasyke i Norge: Slik er det å være smittet.
19. mars 2020
Christine Hanssen Rinaldo:
SARS-CoV-2
27. mars 2020
Christine Hanssen Rinaldo:
SARS-CoV-2 pandemi
13. mars 2020
Christine Hanssen Rinaldo:
Tysk professor mener tap av smakssans kan være koronategn: - Ikke utenkelig, sier UNN-forsker
17. mars 2020
Irene Beate Olsøy,
Stian Henriksen,
Fabian H. Weissbach,
Marthe Larsen,
Katrine Borgen,
Florence Abravanel,
Nassim Kamar,
Eyvind Jakob Paulssen,
Hans H. Hirsch,
Christine Hanssen Rinaldo:
Correction to: Seroprevalence of hepatitis E virus (HEV) in a general adult population in Northern Norway: the Tromsø study (Medical Microbiology and Immunology, (2019), 208, 6, (715-725), 10.1007/s00430-019-00599-5)
Medical Microbiology and Immmunology 2019 Ekstern lenke
Christine Hanssen Rinaldo,
Garth Daryl Tylden:
Medisinsk mikrobiologi, Kapittel 28, Papillomavirus og polyomavirus
Gyldendal Akademisk 2019
Javier Sanchez Romano,
Anett Kristin Larsen,
kjetil helge Elvevold,
Christopher Florian Holte,
Jaione Simon-Santamaria,
Hans H. Hirsch,
Christine Hanssen Rinaldo,
Peter Anthony McCourt,
Karen Kristine Sørensen,
Bård Smedsrød:
SECVIR - The role of scavenger endothelial cells in elimination of virus
2019
Karl Bjørnar Alstadhaug,
Therese Croughs,
Stian Henriksen,
Irini Sereti,
Hans H. Hirsch,
Christine Hanssen Rinaldo:
A patient with idiopathic CD4+ T-cell lymphocytopenia and progressiv mulitifocal leukoencephalopathy: treatment by recombinant interleukin-7 and characterization of polyomavirus JC
2014
Jaione Simon-Santamaria,
Christine H Rinaldo,
Piotr Kardas,
Ruomei Li,
Ivana Malovic,
Kjetil H. Elvevold,
Peter Anthony McCourt,
Bård Smedsrød,
Hans H. Hirsch,
Karen Kristine Sørensen:
Role of scavenger endothelial cells in polyomavirus JC and BK clearance
2014
Christine Hanssen Rinaldo,
Stian Henriksen,
Garth Daryl Tylden,
Hans H. Hirsch:
Reply to "contamination of SVG p12 cells with BK polyomavirus occurred after deposit in the American type culture collection"
Journal of Virology 2014 Ekstern lenke
Christine H Rinaldo,
Hans H. Hirsch:
The human polyomaviruses: from orphans and mutants to patchwork family
APMIS - Journal of Pathologiy, Microbiology and Immunology 2013 Ekstern lenke
Biswa Nath Sharma,
Manfred Marschall,
Stian Henriksen,
Tore Jarl Gutteberg,
Christine H Rinaldo:
Antiviral effects of artesunate on polyomavirus BK replication in primary human renal tubular epithelial cells
Journal of Neurovirology 2013
Christine H Rinaldo,
Biswa Nath Sharma,
Marschall Manfred,
Stian Henriksen,
Tore Jarl Gutteberg:
Effects of Artesunate on Polyomavirus BK Replication in Primary Human Renal Tubular Epithelial Cells
2013
Biswa Nath Sharma,
Manfred Marschall,
Stian Henriksen,
Tore Jarl Gutteberg,
Christine Hanssen Rinaldo:
Antiviral Effects of Artesunate on Polyomavirus BK Replication in Primary Human Kidney Cells
2012
Christine Hanssen Rinaldo,
Ruomei Li,
Biswa Nath Sharma,
Stig Linder,
Tore Jarl Gutteberg,
Hans H. Hirsch:
Polyomavirus BK (BKV) replication in human urothelial cells - role in polyomavirus associated hemorrhagic cystitis and nephropathy
2012
Hans H. Hirsch,
Christiane Beckmann,
Alexis Dumoulin,
Enid Dørmenen,
Christine Bauer,
Christine Hanssen Rinaldo:
Cytomegalovirus and Epstein-Barr Virus PCR quantification: impact of sample matrix and extraction methods in a two-centers comparative study and implementation of the first WHO International Standard for Cytomegalovirus
2012
Jaione Simon-Santamaria,
Ruomei Li,
Piotr Kardas,
Ivana Malovic,
Kjetil H. Elvevold,
Peter Anthony McCourt,
Bård Smedsrød,
Hans Hirsch,
Christine H Rinaldo,
Karen Kristine Sørensen:
Role of liver sinusoidal endothelial cells in blood clearance of polyomavirus BK and JC
2012
Christine H Rinaldo,
Ruomei Li,
Biswa Nath Sharma,
Stig Linder,
Tore Jarl Gutteberg,
Hans H. Hirsch:
Polyomavirus BK (BKV) Replication in Human Urothelial Cells Role in Polyomavirus-Associated Nephropathy and Hemorrhagic Cystitis
American Journal of Transplantation 2012
christine h Rinaldo,
E Bernhoff,
G Tylden,
LJ Kjerpeseth,
TJ Gutteberg,
HH Hirsch:
Leflunomide Interferes with BK Virus by Disrupting the Viral Nuclear Replication Architecture in Renal Tubular Cells
American Journal of Transplantation 2009
Eva Bernhoff,
Garth Daryl Tylden,
LJ Kjerpeseth,
tore jarl Gutteberg,
HH Hirsch,
christine h Rinaldo:
Leflunomide inhibits BK virus replication but simultaneously compromises renal tubular epithelial cell proliferation
Journal of Clinical Virology 2009
tore jarl Gutteberg,
christine h Rinaldo:
Lactoferrin confidential: ancient actor starring in new role?
Transplant Infectious Disease 2008
christine h Rinaldo,
E Bernhoff,
G Tylden,
K Sandvik,
HH Hirsch,
tore jarl Gutteberg:
Time-dependent effect of cidofovir and leflunomide on polyomavirus BK replication and kidney cell viability
American Journal of Transplantation 2008
Bjørn Grinde,
christine h Rinaldo:
Effect of three viruses and interferon on gene expression
Journal of Clinical Virology 2006
Forskningsinteresser
Humane polyomavirus (HPyV): BKPyV og JCPyV
Hepatitt E-virus (HEV)
Cytomegalovirus (CMV)
Herpes simples virus 1 (HSV-1)
SARS-CoV-2
Virus replikasjon, virus-celle interaksjon, patogenese, immunitet, virusindusert kreftutvikling, antiviral behandling, diagnostikk