Bilde av Xing, Zhe
Bilde av Xing, Zhe
Førsteamanuensis / Tannlege (MNTF) Institutt for medisinsk biologi zhe.xing@uit.no +4777645104 Tromsø Her finner du meg

Zhe Xing


Stillingsbeskrivelse

Forskning og undervisning

 Tannlege med kirurgisk og periodontal behandlingskompetanse

 


  • Xiaoli He, Qian Zhao, Ningning Zhang, Junbin Wang, Qingzong Si, Ying Xue m.fl.:
    Impact of a staggered scaffold structure on the mechanical properties and cell response in bone tissue engineering
    Journal of Applied Biomaterials & Functional Materials (JABFM) 2023 ARKIV / DOI
  • Jiazheng Cai, Jing Liu, Jing Yan, Xuexia Lu, Xiaoli Wang, Si Li m.fl.:
    Impact of Resolvin D1 on the inflammatory phenotype of periodontal ligament cell response to hypoxia
    Journal of Periodontal Research 2022 ARKIV / DOI
  • Xiaofeng Jiang, Jing Liu, Si Li, Yingfei Qiu, Xiaoli Wang, Xiaoli He m.fl.:
    The effect of resolvin D1 on bone regeneration in a rat calvarial defect model
    Journal of Tissue Engineering and Regenerative Medicine 2022 ARKIV / DOI
  • Xiaofeng Jiang, Ying Xue, Manal Mustafa, Zhe Xing :
    An updated review of the effects of eicosapentaenoic acid- and docosahexaenoic acid-derived resolvins on bone preservation
    Prostaglandins & other lipid mediators 2022 DOI
  • Zhe Xing, Xiaofeng Jiang, Qingzong Si, Anna Finne-Wistrand, Bin Liu, Ying Xue m.fl.:
    Endochondral ossification induced by cell transplantation of endothelial cells and bone marrow stromal cells with copolymer scaffold using a rat calvarial defect model
    Polymers 2021 DOI
  • Zhe Xing, Jiazheng Cai, Yang Sun, Mengnan Cao, Yi Li, Ying Xue m.fl.:
    Altered surface hydrophilicity on copolymer scaffolds stimulate the osteogenic differentiation of human mesenchymal stem cells
    Polymers 2020 DOI
  • Abedelfattah Atif Taher Omer, Niyaz Abdulbaqi Al-sharabi, Yingfei Qiu, Ying Xue, Yi Li, Masahito Fujio m.fl.:
    Biological responses of dental pulp cells to surfaces modified by collagen 1 and fibronectin
    Journal of Biomedical Materials Research. Part A 2020 DOI
  • Sunita Sharma, Ying Xue, Zhe Xing, Mohammed Ahmed Yassin, Yang Sun, James Lorens m.fl.:
    Adenoviral mediated mono delivery of BMP2 is superior to the combined delivery of BMP2 and VEGFA in bone regeneration in a critical-sized rat calvarial bone defect
    Bone Reports 2019 ARKIV / DOI
  • Mohammed Ahmed Alamin Yousif Yassin, Kamal Babikeir Eln Mustafa, Zhe Xing, Yang Sun, Kristine Eldevik Fasmer, Thilo Waag m.fl.:
    A copolymer scaffold functionalized with nanodiamond particles enhances osteogenic metabolic activity and bone regeneration
    Macromolecular Bioscience 2017 DOI
  • Masahito Fujio, Zhe Xing, Niyaz Abdulbaqi Abdulmajid Al-Sharabi, Ying Xue, Akihito Yamamoto, Hideharu Hibi m.fl.:
    Conditioned media from hypoxic-cultured human dental pulp cells promotes bone healing during distraction osteogenesis
    Journal of Tissue Engineering and Regenerative Medicine 27. november 2015 ARKIV / DOI
  • Salwa Suliman, Zhe Xing, X Wu, Ying Xue, Torbjørn Østvik Pedersen, Y Sun m.fl.:
    Release and bioactivity of bone morphogenetic protein-2 are affected by scaffold binding techniques in vitro and in vivo
    Journal of Controlled Release 2015 ARKIV / DOI
  • Y Sun, Anna Finne-Wistrand, T. Waag, Zhe Xing, Mohammed Ahmed Alamin Yousif Yassin, A Yamamoto m.fl.:
    Reinforced degradable biocomposite by homogenously distributed functionalized nanodiamond particles
    Macromolecular Materials and Engineering 2015 DOI
  • Mohammed Ahmed Alamin Yousif Yassin, Knut N. Leknes, Torbjørn Østvik Pedersen, Zhe Xing, Yang Sun, Stein Atle Lie m.fl.:
    Cell seeding density is a critical determinant for copolymer scaffolds-induced bone regeneration
    Journal of Biomedical Materials Research. Part A 2015 ARKIV / DOI
  • Yang Sun, Zhe Xing, Ying Xue, Kamal Babikeir Eln Mustafa, Anna Finne-Wistrand, Ann-Christine Albertsson :
    Surfactant as a critical factor when tuning the hydrophilicity in three-dimensional polyester-based scaffolds: Impact of hydrophilicity on their mechanical properties and the cellular response of human osteoblast-like cells
    Biomacromolecules 2014 DOI
  • Zhenghui Wang, Xiaoli Li, Xijing He, Baojun Wu, Min Xu, Huimin Chang m.fl.:
    Delivery of the Sox9 gene promotes chondrogenic differentiation of human umbilical cord blood-derived mesenchymal stem cells in an in vitro model
    Brazilian Journal of Medical and Biological Research 2014 ARKIV / DOI
  • Torbjørn Østvik Pedersen, Anna Blois, Ying Xue, Zhe Xing, Yang Sun, Anna Finne-Wistrand m.fl.:
    Mesenchymal stem cells induce endothelial cell quiescence and promote capillary formation
    Stem Cell Research & Therapy 2014 ARKIV / DOI
  • Ying Xue, Zhe Xing, Anne Isine Bolstad, Thomas E van Dyke, Kamal Babikeir Eln Mustafa :
    Co-culture of human bone marrow stromal cells with endothelial cells alters gene expression profiles
    International Journal of Artificial Organs 2013 DOI
  • Torbjørn Østvik Pedersen, Zhe Xing, Anna Finne-Wistrand, Sølve Hellem, Kamal Babikeir Eln Mustafa :
    Hyperbaric oxygen stimulates vascularization and bone formation in rat calvarial defects
    International Journal of Oral & Maxillofacial Surgery 2013 DOI
  • Torbjørn Østvik Pedersen, Anna Blois, Zhe Xing, Ying Xue, Yang Sun, Anna Finne-Wistrand m.fl.:
    Endothelial microvascular networks affect gene-expression profiles and osteogenic potential of tissue-engineered constructs
    Stem Cell Research & Therapy 2013 DOI
  • Zhe Xing, Torbjørn Østvik Pedersen, Xujung Wu, Ying Xue, Yang Sun, Anna Finne-Wistrand m.fl.:
    Biological effects of functionalizing copolymer scaffolds with nanodiamond particles
    Tissue Engineering 2013 DOI
  • Zhe Xing, Ying Xue, A-F Wistrand, ZQ Yang, Kamal Babikeir Eln Mustafa :
    Copolymer cell/scaffold constructs for bone tissue engineering: Co-culture of low ratios of human endothelial and osteoblast-like cells in a dynamic culture system
    Journal of Biomedical Materials Research. Part A 2013 DOI
  • Yang Sun, Anna Finne-Wistrand, Ann-Christine Albertsson, Zhe Xing, Kamal Babikeir Eln Mustafa, Wim J. Hendrikson m.fl.:
    Degradable amorphous scaffolds with enhanced mechanical properties and homogeneous cell distribution produced by a three-dimensional fiber deposition method
    Journal of Biomedical Materials Research. Part A 2012 DOI
  • Torbjørn Pedersen, Anna Blois, Ying Xue, Zhe Xing, Michele Cottler-Fox, Inge Fristad m.fl.:
    Osteogenic stimulatory conditions enhance growth and maturation of endothelial cell microvascular networks in culture with mesenchymal stem cells
    Journal of Tissue Engineering 2012 DOI
  • Zhe Xing, Ying Xue, Staffan Dånmark, Kerstin Schander, Siren Hammer Østvold, Kristina Fyrberg Arvidson m.fl.:
    Effect of endothelial cells on bone regeneration using poly(L-lactide-co-1,5-dioxepan-2-one) scaffolds
    Journal of Biomedical Materials Research. Part A 2011 DOI
  • Zhe Xing, Ying Xue, Staffan Dånmark, Anna Finne-Wistrand, Kristina Fyrberg Arvidson, Sølve Hellem m.fl.:
    Comparison of short-run cell seeding methods for poly(L-lactide-co-1,5-dioxepan-2-one) scaffold intended for bone tissue engineering
    International Journal of Artificial Organs 2011 DOI
  • Ying Xue, Staffan Dånmark, Zhe Xing, Kristina Fyrberg Arvidson, Ann-Christine Albertsson, Sølve Hellem m.fl.:
    Growth and differentiation of bone marrow stromal cells on biodegradable polymer scaffolds: An in vitro study
    Journal of Biomedical Materials Research. Part A 2010 DOI
  • Zheng-Hui Wang, Zhuang-Qun Yang, Xi-Jing He, Kamal Babikeir Eln Mustafa, Zhe Xing :
    Lentivirus-mediated knockdown of aggrecanase-1 and-2 promotes chondrocyte-engineered cartilage formation in vitro
    Biotechnology and Bioengineering 2010 DOI
  • Ying Xue, Zhe Xing, Sølve Hellem, Kristina Fyrberg Arvidson, Kamal Babikeir Eln Mustafa :
    Endothelial cells influence the osteogenic potential of bone marrow stromal cells
    Biomedical engineering online 2009 DOI
  • Mohammed Ahmed Alamin Yousif Yassin, Knut N. Leknes, Kamal Babikeir Eln Mustafa, Zhe Xing, Anna Finne-Wistrand :
    Surface hydrophilicity: a key factor i loping bone tissue engineering constructs
    Universitetet i Bergen 2017
  • Yi-Chen Wang, Xiao-Ming Li, Gan-Ping Zhong, Zhe Xing, Zhi-Ping Wang :
    Superficial angiomyxoma of penis: A case report of a 6-year follow-up
    Asian Journal of Andrology (AJA) 2017 DOI
  • MA Yassin, Knut N. Leknes, Torbjørn Østvik Pedersen, Y Sun, Zhe Xing, Anna Finne-Wistrand m.fl.:
    In Tissue Engenieering: Influence Of BMSCs Density on Bone Regeneration
    2014
  • Zhe Xing, Torbjørn Østvik Pedersen, Anna Finne-Wistrand, Ying Xue, Kamal Babikeir Eln Mustafa :
    Chondral ossification from copolymer scaffolds loaded with co-cultured cells
    2014
  • Torbjørn Østvik Pedersen, AL Blois, Ying Xue, Zhe Xing, Anna Finne-Wistrand, J.B. Lorens m.fl.:
    Prevascularization of tissue-engineered constructs with endothelial and mesenchymal stem cells
    2014
  • Torbjørn Østvik Pedersen, Anna Blois, Zhe Xing, Ying Xue, Yang Sun, Anna Finne-Wistrand m.fl.:
    Endothelial Microvascular Networks Influence Gene Expression Profiles in MSCs
    2013
  • Torbjørn Østvik Pedersen, Anna Blois, Ying Xue, Zhe Xing, Anna Finne-Wistrand, James Lorens m.fl.:
    Prevascularization of tissue-engineered constructs with endothelial and mesenchymal stem cells
    2013
  • Masahito Fujio, Niyaz Abdulbaqi Abdulmajid Al-Sharabi, Zhe Xing, Ying Xue, Akihito Yamamoto, Hideharu Hibi m.fl.:
    Culture conditions for human Dental Pulp Cells affect regenerative potential of conditioned media
    2013
  • Zhe Xing :
    Bone tissue engineering: in vitro and in vivo studies of the role of endothelial cells and surface modification of copolymer scaffolds
    Universitetet i Bergen 2012 OMTALE
  • Torbjørn Pedersen, Anna Blois, Ying Xue, Zhe Xing, Michele Cottler-Fox, Inge Fristad m.fl.:
    Osteogenic conditions stimulate microvascular networks – establishing culture conditions for stem cell based reconstruction of bone defects
    2012
  • Zhe Xing, Sølve Hellem, Ying Xue, Staffan Dånmark, Kristina Fyrberg Arvidson, A-F Wistrand m.fl.:
    ECs co-cultured with BMSCs in poly(L-lactide-co-1,5-dioxepan-2-one) scaffolds enhanced bone regeneration
    2011
  • Ying Xue, Zhe Xing, AI Bolstad, Sølve Hellem, Kristina Fyrberg Arvidson, Kamal Babikeir Eln Mustafa :
    Gene expression profiles of BMSC cocultured with EC
    2011
  • Zhe Xing, Sølve Hellem, Ying Xue, Staffan Dånmark, Kristina Fyrberg Arvidson, A-F Wistrand m.fl.:
    ECs co-cultured with BMSCs in poly(L-lactide-co-1,5-dioxepan-2-one) scaffolds enhanced bone regeneration
    Journal of Dental Research 2011
  • Ying Xue, Zhe Xing, AI Bolstad, Sølve Hellem, Kristina Fyrberg Arvidson, Kamal Babikeir Eln Mustafa :
    Gene expression profiles of BMSC cocultured with EC
    Journal of Dental Research 2011
  • Zhe Xing, Ying Xue, Staffan Dånmark, Kristina Fyrberg Arvidson, Sølve Hellem, B. Elnnour Kamal :
    Endothelial progenitor cells enhanced bone regeneration on poly(L-lactide-co-1,5-dioxepan-2-one) scaffold
    2010
  • Kerstin Schander, Kristina Fyrberg Arvidson, B. Elnnour Kamal, Anne Isine Bolstad, Zhe Xing, Ying Xue m.fl.:
    Development of a novel polymer scaffold for tissue engineering
    2010
  • Kerstin Schander, Kamal Babiker Ein Mustafa, Kristina Fyrberg Arvidson, Anne Isine Bolstad, Anna Finne-Wistrand, Staffan Dånmark m.fl.:
    Utveckling av ett nytt scaffold før Tissue Engineering
    2010
  • Kerstin Schander, Kamal Babikeir Eln Mustafa, Kristina Fyrberg Arvidson, Anne Isine Bolstad, Staffan Dånmark, Sølve Hellem m.fl.:
    Presentasjon: Vestlandsmøtet (NTF) 2009 Bergen, Norge. Tissue engineering, snart en del av vår vardag!
    2009
  • Zhe Xing, Ying Xue, Kristina Fyrberg Arvidson, Kamal Babikeir Eln Mustafa, Sølve Hellem :
    In a direct contact co-culture model: effect of endothelial cells on growth and differentiation of osteogenic cells
    2009
  • Zhe Xing, Ying Xue, Kerstin Schander, Staffan Dånmark, Siren Hammer Østvold, Sølve Hellem m.fl.:
    The role of endothelial progenitor cells for an improved bone regeneration model
    2009
  • Ying Xue, Zhe Xing, Staffan Dånmark, Sølve Hellem, Kristina Fyrberg Arvidson, Kamal Babikeir Eln Mustafa :
    GROWTH AND DIFFERENTIATION OF MESENCHYMAL STEM CELLS ON BIODEGRADABLE POLYMER SCAFFOLDS
    2009
  • Zhe Xing, Ying Xue, Staffan Dånmark, Kristina Fyrberg Arvidson, Kamal Mustafa, Sølve Hellem :
    Cellular spreading, growth and differentiation in 3D copolymer
    2008

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    Forskningsinteresser

    Key methods:

    Organ-on-a-chip, bioreactor, 3D printing and dynamic cultures

    Biomaterials and scaffolding

    Imaging Mass Cytometry and image analysis

    Tromsø study data analysis

     

    Research field:

    Tissue engineering and regeneration medicine

    Resolvins and inflammation resolution, oral cancer

    Osteonecrosis of the Jaw (ONJ). Periodontitis.

    Oral Manifestations of Systemic Lupus Erythematosus

    n-3 PUFAs intake and oral health

    Undervisning

    Oral anatomy, histology and embryology

    • ODO-2010- oral anatomy and histology,  responsible for the course
    • ODO-1004 - teaching oral anatomy
    • TPL-1006 - teaching tooth morphology
    • MED-2501 -  teaching tooth and face embryology

    Supervised (incl. ongoing) 14 master og 2 PhD students in Norway and abroad.




    CV

    2022- Associate Professor, PI, IMB, Helsefak, UiT The Arctic University of Norway

    2019-2022 Professor, PI, group leader, Lanzhou University

    2018 Clinical instructor for periodontology, Dept. of Clinical Dentistry, University of Bergen

    2016-2022 Private dental practice, Bergen, Norway

    2015-2018 Staff Engineer, Department of Clinical Science, University of Bergen

    2013 Researcher, 6 months, Nagoya University, Japan

    2012-2015 Post doctor, Dept. of Clinical Dentistry, University of Bergen

    2007-2012  PhD., Dept. of Clinical Dentistry, University of Bergen

    2005-2007 Oral surgeon, Resident, and Instructor, Xi‘an Jiaotong University

    2002-2005  Master of Medicine, oral and maxillofacial surgery

    1997-2002  Bachelor of Medicine, general dentist

     

    Research and clinical stays at abroad institutes:

    Harvard University / The Forsyth Institute, Boston, USA.

    Peking University, dental school, 3 weeks

    European Surgeon Training Center, Hamburg, Germany.

    Bruker microCT headquarter, Antwerpen, Belgium.

    Wurzburg University, Germany.

    Innsbruck Medical University, Innsbruck, Austria.

    JPK instruments AG, Berlin, Germany.

    Fraunhofer, Stuttgart, Germany.

    Royal Institute of Technology, Stockholm, Sweden.

    Århus University, Danmark.


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