Foto: Christian Halvorsen
Christer Einvik
Swapnil Bhavsar,
Lotte Olsen,
Cecilie Løkke,
Jan Koster,
Trond Flægstad,
Christer Einvik
:
Hsa-miR-323a-3p functions as a tumor suppressor and targets STAT3 in neuroblastoma cells
Peter Utnes,
Cecilie Løkke,
Trond Flægstad,
Christer Einvik
:
Clinically Relevant Biomarker Discovery in High-Risk Recurrent Neuroblastoma
Roth Sarah Andrea,
Øyvind Holsbø Hald,
Steffen Fuchs,
Cecilie Løkke,
Ingvild Mikkola,
Trond Flægstad
m.fl.:
MicroRNA-193b-3p represses neuroblastoma cell growth via downregulation of Cyclin D1, MCL-1 and MYCN
Swapnil Parashram Bhavsar,
Cecilie Løkke,
Trond Flægstad,
Christer Einvik
:
Hsa-miR-376c-3p targets cyclin D1 and induces G1-cell cycle arrest in neuroblastoma cells
Øyvind Holsbø Hald,
Lotte Olsen,
Gabriel Gallo-Oller,
Lotta Helena Maria Elfman,
Cecilie Løkke,
Per Kogner
m.fl.:
Inhibitors of ribosome biogenesis repress the growth of MYCN-amplified neuroblastoma.
Sarah A Roth,
Erik Knutsen,
Tonje Fiskaa,
Peter Andree Utnes,
Swapnil Parashram Bhavsar,
Øyvind Hald
m.fl.:
Next generation sequencing of microRNAs from isogenic neuroblastoma cell lines isolated before and after treatment
Cancer Letters 2016 DOI
Malin Wickström,
Cecilia Dyberg,
Jelena Milosevic,
Christer Einvik,
Raul Calero,
Baldur Sveinbjørnsson
m.fl.:
Wnt/β-catenin pathway regulates MGMT gene expression in cancer and inhibition of Wnt signalling prevents chemoresistance
Bjørn Helge Haug,
Øyvind Hald,
Peter Utnes,
Sarah A Roth,
Cecilie Løkke,
Trond Flægstad
m.fl.:
Exosome-like extracellular vesicles from MYCN-amplified neuroblastoma cells contain oncogenic miRNAs
Anticancer Research 2015 SAMMENDRAG / ARKIV
Hanna Zirath,
Anna Frenzel,
Ganna Oliynyk,
Lova Segerstrom,
Ulrica K. Westermark,
Karin Larsson
m.fl.:
MYC inhibition induces metabolic changes leading to accumulation of lipid droplets in tumor cells
Proceedings of the National Academy of Sciences of the United States of America (PNAS) 2013 DOI
Jochen Buechner,
Christer Einvik
:
N-myc and Noncoding RNAs in Neuroblastoma
Molecular Cancer Research 2012 DOI
Jørn Remi Henriksen,
Bjørn Helge Haug,
Jochen Büchner,
Ellen Tømte,
Cecilie Løkke,
Trond Flaegstad
m.fl.:
Conditional expression of retrovirally delivered anti-MYCN shRNA as an in vitro model system to study neuronal differentiation in MYCN-amplified neuroblastoma
Jochen Buechner,
Ellen Tømte,
Bjørn Helge Haug,
Jørn Remi Henriksen,
Cecilie Løkke,
Trond Flægstad
m.fl.:
Tumour-suppressor microRNAs let-7 and mir-101 target the proto-oncogene MYCN and inhibit cell proliferation in MYCN-amplified neuroblastoma
Bjørn Helge Haug,
Jørn Remi Henriksen,
Jochen Buechner,
Dirk Geerts,
Ellen Tømte,
Per Kogner
m.fl.:
MYCN-regulated miRNA-92 inhibits secretion of the tumor suppressor DICKKOPF-3 (DKK3) in neuroblastoma
Carcinogenesis 2011 DOI
Jørn Remi Henriksen,
Jochen Büchner,
Cecilie Løkke,
Trond Flaegstad,
Christer Einvik
:
Inhibition of Gene Function in Mammalian Cells Using Short-Hairpin RNA (shRNA)
Humana Press 2011 DOI
Jochen Büchner,
Jørn Remi Henriksen,
Bjørn Helge Haug,
Ellen Tømte,
Trond Flaegstad,
Christer Einvik
:
Inhibition of mir-21, which is up-regulated during MYCN knockdown-mediated differentiation, does not prevent differentiation of neuroblastoma cells
Differentiation 2011 DOI
Henrik Nielsen,
christer Einvik,
Thomas E Lentz,
MM Hedegaard,
Steinar Johansen
:
A conformational switch in the DiGIR1 ribozyme involved in release and folding of the downstream I-DirI mRNA
RNA: A publication of the RNA Society 2009 DOI
B Beckert,
Henrik Nielsen,
christer Einvik,
Steinar Johansen,
E Westhof,
B Masquida
:
Molecular modelling of the GIR1 branching ribozyme gives new insight into evolution of structurally related ribozymes
EMBO Journal 2008 DOI
Jørn Remi Henriksen,
cecilie LØkke,
Martin Hammerø,
Dirk Geerts,
R Versteeg,
Trond Flaegstad
m.fl.:
Comparison of RNAi efficiency mediated by tetracycline-responsive H1 and U6 promoter variants in mammalian cell lines
Nucleic Acids Research (NAR) 2007 DOI
Tonje Fiskaa,
Eirik Wasmuth Lundblad,
Jørn Remi Henriksen,
Steinar Johansen,
Christer Einvik
:
RNA reprogramming of alpha-mannosidase mRNA sequences in vitro by myxomycete group IC1 and IE ribozymes
The FEBS Journal 2006
Odd Gunnar Wikmark,
Christer Einvik,
JF De Jonckheere,
Steinar Johansen
:
Short-term sequence evolution and vertical inheritance of the Naegleria twin-ribozyme group I intron
BMC Evolutionary Biology 2006
Odd Gunnar Wikmark,
Christer Einvik,
Johan F De Jonckheere,
Steinar Daae Johansen
:
Short-term sequence evolution and vertical inheritance of the Naegleria twin-ribozyme group I intron
BMC Ecology and Evolution 2006 DOI
Eirik Wasmuth Lundblad,
Christer Einvik,
S Rønning,
Kari B. Haugli,
Steinar Johansen
:
Twelve group I Introns in the same pre-rRNA transcript of the myxomycete Fuligo septica: RNA processing and evolution
Molecular Biology and Evolution (MBE) 2004
Christer Einvik,
Tonje Fiskaa,
Eirik Wasmuth Lundblad,
Steinar Johansen
:
Optimization and application of the group I ribozyme trans-splicing reaction
Methods in molecular biology 2004
Henrik Nielsen,
Tonje Fiskaa,
Åsa Birna Birgisdottir,
Peik Haugen,
christer Einvik,
Steinar Johansen
:
The ability to form full-length intron RNA circles is a general property of nuclear group I introns
RNA: A publication of the RNA Society 2003
Steinar Johansen,
christer Einvik,
Henrik Nielsen
:
DiGIR1 and NaGIR1: naturally occurring group I-like ribozymes with unique core organization and evolved biological role
Biochimie 2002
Steinar Daae Johansen,
morten Andreassen,
Åsa birna Birgisdottir,
Dag-Hugo Coucheron,
Christer Einvik,
Tonje Fiskaa
m.fl.:
Group I introns are very common in nuclear SSU rDNA and LSU rDNA of Myxomycetes
Scripta Botanica Belgica 2002
christer Einvik,
Henrik Nielsen,
R Nour,
Steinar Johansen
:
Flanking sequences with essential role in hydrolysis of a self-cleaving group I-like ribozyme
Nucleic Acids Research (NAR) 2000
Yusuke Suenaga,
Christer Einvik,
Atsushi Takatori,
Yuyan Zhu
:
Editorial: Molecular Mechanisms and Treatment of MYCN-Driven Tumors
Frontiers in Oncology 2021 DOI
Trond Flægstad,
Bjørn Helge Haug,
Jochen Buechner,
Jørn Remi Henriksen,
Per Kogner,
Tommy Martinson
m.fl.:
MYCN-REGULATED MIRNA-92 INHIBITS SECRETION OF THE TUMOR SUPPRESSOR DICKKOPF-3 (DKK3) IN NEUROBLASTOMA
Pediatric Blood & Cancer 2011
Trond Flaegstad,
christer Einvik,
Jørn Remi Henriksen
:
Targeted MYCN suppression and its effect on miRNA in neuroblastoma
UiT Norges arktiske universitet 2010 FULLTEKST
Jørn Remi Henriksen,
Bjørn Helge Haug,
Jochen Büchner,
cecilie LØkke,
Trond Flaegstad,
christer Einvik
:
Conditional MYCN knockdown using shRNAs encoded by retrovirus vectors
2010
Bjørn Helge Haug,
Jørn Remi Henriksen,
Baldur Sveinbjørnsson,
Trond Flaegstad,
christer Einvik
:
The tumour suppressor DKK3 is a direct target of MYCN regulated miRNAs
2010
Jørn Remi Henriksen,
Jochen Büchner,
Bjørn Helge Haug,
christer Einvik,
Trond Flaegstad
:
Combination of RA Treatment and MYCN-knockdown in MYCN Amplified Neuroblastoma
2010
Trond Flaegstad,
Jochen Büchner,
Jørn Remi Henriksen,
cecilie LØkke,
Ellen Tømte,
Bjørn Helge Haug
m.fl.:
MYCN PARTICIPATES IN A REGULATORY MIRNA NETWORK IN MYCN-AMPLIFIED NEUROBLASTOMA
Pediatric Blood & Cancer 2009
Jochen Büchner,
Jørn Remi Henriksen,
cecilie LØkke,
Trond Flaegstad,
christer Einvik
:
Effect of MYCN downregulation on microRNA expression in neuroblastoma
2008
Jochen Büchner,
Jørn Remi Henriksen,
cecilie LØkke,
Trond Flaegstad,
christer Einvik
:
MicroRNA-101 as a potential regulator of MCYN expression in neuroblastoma
2008
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Forskningsinteresser
Onkologi (forskningsgruppe for pediatri)