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Institutt for medisinsk biologi neoma.boardman@uit.no +4777644681 Tromsø MH L7.221 B

Neoma Tove Boardman


Førsteamanuensis

Stillingsbeskrivelse

1.amanuensis


  • Hansen, Synne; Pedersen, Tina Myhre; Marin, Julie; Boardman, Neoma Tove; Shah, Ajay M.; Aasum, Ellen; Hafstad, Anne Dragøy. Overexpression of NOX2 Exacerbates AngII‐Mediated Cardiac Dysfunction and Metabolic Remodelling. Antioxidants 2022; Volum 11 (1). ISSN 2076-3921.s doi: 10.3390/antiox11010143.
  • Boardman, Neoma Tove; Migally, Baher; Pileggi, Chantal; Parmar, Gaganwir S.; Xuan, Jian Ying; Menzies, Keir; Harper, Mary-Ellen. Glutaredoxin-2 and Sirtuin-3 deficiencies impair cardiac mitochondrial energetics but their effects are not additive. Biochimica et Biophysica Acta - Molecular Basis of Disease 2020; Volum 1867 (1). ISSN 0925-4439.s doi: 10.1016/j.bbadis.2020.165982.
  • Boardman, Neoma Tove; Pedersen, Tina Myhre; Rossvoll, Line; Hafstad, Anne Dragøy; Aasum, Ellen. Diet-induced obese mouse hearts tolerate an acute high fatty acid exposure that also increases ischemic tolerance. American Journal of Physiology. Heart and Circulatory Physiology 2020. ISSN 0363-6135.s doi: 10.1152/ajpheart.00284.2020.
  • Hafstad, Anne Dragøy; Hansen, Synne Simonsen; Lund, Jim; Santos, Celio X.C.; Boardman, Neoma Tove; Shah, Ajay M.; Aasum, Ellen. NADPH oxidase 2 mediates myocardial oxygen wasting in obesity. Antioxidants 2020; Volum 9 (2). ISSN 2076-3921.s 1 - 17.s doi: 10.3390/antiox9020171.
  • Makrecka-Kuka, Marina; Liepinsh, Edgars; Murray, Andrew J.; Lemieux, Hélène; Dambrova, Maija; Tepp, Kersti; Puurand, Marju; Käämbre, Tuuli; Han, Woo H.; de Goede, Paul; O'Brien, Katie A.; Turan, Belma; Tuncay, Erkan; Olgar, Yusuf; Rolo, Anabela P.; Palmeira, Carlos M.; Boardman, Neoma Tove; Wüst, Rob C.I.; Larsen, Terje. Altered mitochondrial metabolism in the insulin-resistant heart. Acta Physiologica 2019; Volum 00:e13430. ISSN 1748-1708.s 1 - 26.s doi: 10.1111/apha.13430.
  • Boardman, Neoma Tove; Falck, Aleksander Tank; Lund, Trine; Chu, Xi; Martin, Armas Maria Montserrat; Norvik, Jon Viljar; Jenssen, Trond Geir; Ytrehus, Kirsti. Human concentrations of uric acid scavenges adaptive and maladaptive ROS in isolated rat hearts subjected to ischemic stress. Canadian Journal of Physiology and Pharmacology 2019; Volum 98 (3). ISSN 0008-4212.s 139 - 146.s doi: 10.1139/cjpp-2019-0024.
  • Boardman, Neoma Tove; Rossvoll, Line; Lund, Jim; Hafstad, Anne Dragøy; Aasum, Ellen. 3-Weeks of Exercise Training Increases Ischemic-Tolerance in Hearts From High-Fat Diet Fed Mice. Frontiers in Physiology 2019; Volum 10. ISSN 1664-042X.s 1 - 7.s doi: 10.3389/fphys.2019.01274.
  • Pedersen, Tina Myhre; Boardman, Neoma; Hafstad, Anne Dragøy; Aasum, Ellen. Isolated perfused working hearts provide valuable additional information during phenotypic assessment of the diabetic mouse heart. PLOS ONE 2018; Volum 13 (10). ISSN 1932-6203.s doi: 10.1371/journal.pone.0204843.
  • Boardman, Neoma; Hafstad, Anne Dragøy; Lund, Jim; Rossvoll, Line; Aasum, Ellen. Exercise of obese mice induces cardioprotection and oxygen sparing in hearts exposed to high-fat load. American Journal of Physiology. Heart and Circulatory Physiology 2017; Volum 313 (5). ISSN 0363-6135.s 1054 - 1062.s doi: 10.1152/ajpheart.00382.2017.
  • Hafstad, Anne Dragøy; Boardman, Neoma Tove; Aasum, Ellen. How Exercise May Amend Metabolic Disturbances in Diabetic Cardiomyopathy. Antioxidants and Redox Signaling 2015; Volum 22 (17). ISSN 1523-0864.s doi: 10.1089/ars.2015.6304.
  • Lund, Jim; Hafstad, Anne Dragøy; Boardman, Neoma Tove; Rossvoll, Line; Rolim, Natale Pinheiro Lage; Ahmed, Muhammad Shakil; Florholmen, Geir; Attramadal, Håvard; Wisløff, Ulrik; Larsen, Terje; Aasum, Ellen. Exercise training promotes cardioprotection through oxygen-sparing action in high fat-fed mice. American Journal of Physiology. Heart and Circulatory Physiology 2015; Volum 308 (8). ISSN 0363-6135.s H823 - H829.s doi: 10.1152/ajpheart.00734.2014.
  • Bakkehaug, Jens Petter; Kildal, Anders Benjamin; Engstad, Erik Torgersen; Boardman, Neoma Tove; Næsheim, Torvind; Rønning, Leif R.; Aasum, Ellen; Larsen, Terje; Myrmel, Truls; How, Ole-Jakob. Myosin activator omecamtiv mecarbil increases myocardial oxygen consumption and impairs cardiac efficiency mediated by resting myosin ATPase activity. Circulation: Heart Failure 2015; Volum 8 (4). ISSN 1941-3289.s 766 - 775.s doi: 10.1161/CIRCHEARTFAILURE.114.002152.
  • Boardman, Neoma Tove; Aronsen, Jan Magnus; Louch, William Edward; Sjaastad, Ivar; Willoch, Frode; Christensen, Geir Arve; Sejersted, Ole M; Aasum, Ellen. Impaired left ventricular mechanical and energetic function in mice after cardiomyocyte-specific excision of Serca2. American Journal of Physiology. Heart and Circulatory Physiology 2014. ISSN 0363-6135.s doi: 10.1152/ajpheart.00741.2013.
  • Boardman, Neoma Tove; Aronsen, Jan Magnus; Louch, William Edward; Sjaastad, Ivar; Willoch, Frode; Christensen, Geir Arve; Sejersted, Ole M; Aasum, Ellen. Impaired left ventricular mechanical and energetic function in mice after cardiomyocyte-specific excision of Serca2. American Journal of Physiology. Heart and Circulatory Physiology 2014; Volum 306 (7). ISSN 0363-6135.s H1018 - H1024.s doi: 10.1152/ajpheart.00741.2013.
  • Hafstad, Anne Dragøy; Boardman, Neoma Tove; Lund, Jim; Hagve, Martin; Khalid, Ahmed Murtaz; Wisløff, Ulrik; Larsen, Terje; Aasum, Ellen. High intensity interval training alters substrate utilization and reduces oxygen consumption in the heart. Journal of applied physiology 2011; Volum 111 (5). ISSN 8750-7587.s 1235 - 1241.s doi: 10.1152/japplphysiol.00594.2011.
  • Boardman, Neoma Tove; Larsen, Terje; Severson, david lester; Essop, M Fadiel; Aasum, Ellen. Chronic and acute exposure of mouse hearts to fatty acids increases oxygen cost of excitation-contraction coupling. American Journal of Physiology. Heart and Circulatory Physiology 2011; Volum 300 (5). ISSN 0363-6135.s H1631 - H1636.s doi: 10.1152/ajpheart.01190.2010.
  • Khalid, Ahmed Murtaz; Hafstad, Anne Dragøy; Larsen, Terje; Severson, david lester; Boardman, Neoma Tove; Hagve, Martin; Berge, Rolf Kristian; Aasum, Ellen. Cardioprotective effect of the PPAR ligand tetradecylthioacetic acid in type 2 diabetic mice. American Journal of Physiology. Heart and Circulatory Physiology 2011; Volum 300 (6). ISSN 0363-6135.s H2116 - H2122.s doi: 10.1152/ajpheart.00357.2010.
  • Boardman, Neoma Tove; Hafstad, Anne Dragøy; Larsen, Terje; Severson, DL; Aasum, Ellen. Increased O-2 cost of basal metabolism and excitation-contraction coupling in hearts from type 2 diabetic mice. American Journal of Physiology. Heart and Circulatory Physiology 2009; Volum 296 (5). ISSN 0363-6135.s H1373 - H1379.s doi: 10.1152/ajpheart.01264.2008.
  • How, Ole-Jakob; Larsen, Terje; Hafstad, Anne Dragøy; Khalid, Ahmed Murtaz; Myhre, Eivind S. P.; Myrray, AJ; Boardman, Neoma; Cole, M; Clarke, Kieran; Severson, David Lester; Aasum, Ellen. Rosiglitazone treatment improves cardiac efficiency in hearts from diabetic mice. Archives of Physiology and Biochemistry 2007; Volum 113 (4). ISSN 1381-3455.s 211 - 220.
  • Boardman, Neoma Tove. Harnessing the protective role of OPA-1 in diabetic cardiomyopathy. Acta Physiologica 2020; Volum 221 (1). ISSN 1748-1708.s doi: 10.1111/apha.13466.
  • Ytrehus, Kirsti; Boardman, Neoma Tove; Lund, trine; Zykova, Svetlana; Jenssen, Trond Geir. The uric acid paradox, a confounder in cardiovascular research and experimental studies of cardioprotection. Conditioning Medicine 2019; Volum 2 (1). ISSN 2577-3240.s 40 - 49.
  • Bakkehaug, Jens Petter; Kildal, Anders Benjamin; Engstad, Erik Torgersen; Boardman, Neoma Tove; Næsheim, Torvind; Rønning, Leif R.; Aasum, Ellen; Larsen, Terje; Myrmel, Truls; How, Ole-Jakob. Response to Letter Regarding Article, "Myosin Activator Omecamtiv Mecarbil Increases Myocardial Oxygen Consumption and Impairs Cardiac Efficiency Mediated by Resting Myosin ATPase Activity". Circulation: Heart Failure 2015; Volum 8 (6). ISSN 1941-3289.s 1142 - 1142.s doi: 10.1161/CIRCHEARTFAILURE.115.002548.
  • Boardman, Neoma Tove; Aasum, Ellen. Cardiometabolic adaptations to altered fuel supply, Ca2+ handling and exercise. 2011 ISBN 978-82-7589-305-3.
  • Hafstad, Anne Dragøy; Boardman, Neoma Tove; Lund, Jim; Hagve, Martin; Wisløff, Ulrik; Larsen, Terje; Aasum, Ellen. Exercise-induced Increase In Cardiac Efficiency - The Impact of Intensity. Circulation 2009. ISSN 0009-7322.s S880 - .
  • Hafstad, Anne Dragøy; Boardman, Neoma Tove; Lund, Jim; Hagve, Martin; Wisløff, Ulrik; Larsen, Terje; Aasum, Ellen. Metabolic adaptations in the physiologically hypertrophied heart. 7th annual meeting of the Society for Heart and Vascular Metabolism (SHVM) 2009-08-23 - 2009-08-26 2009.
  • Hafstad, Anne Dragøy; Boardman, Neoma Tove; Lund, Jim; Hagve, Martin; Wisløff, Ulrik; Larsen, Terje; Aasum, Ellen. Exercise-induced Increase In Cardiac Efficiency - The Impact of Intensity. American Heart Association 2009-11-14 - 2009-11-18 2009.
  • Boardman, Neoma Tove; Hafstad, Anne Dragøy; Larsen, Terje; Severson, david lester; Aasum, Ellen. Oxygen cost of E-C coupling in the diabetic heart. Hjerteforum 2008; Volum 2. ISSN 0802-1465.s 128 - .
  • Hafstad, Anne Dragøy; Khalid, Ahmed Murtaz; Boardman, Neoma Tove; Larsen, Terje; Aasum, Ellen. The pan ppar ligand tta has a direct cardiometabolic effect in normal and diabetic mice. 6th annual meeting of the SHVM 2008-06-29 - 2008-07-01 2008.
  • Boardman, Neoma Tove; Hafstad, Anne Dragøy; Larsen, Terje; Severson, david lester; Aasum, Ellen. The O2 cost of basal metabolism and excitation-contraction coupling is increased in hearts from type 2 diabetic mice. 6th annual meeting of the SHVM 2008-06-29 - 2008-07-01 2008.
  • Boardman, Neoma Tove; Hafstad, Anne Dragøy; Larsen, Terje; Severson, david lester; Aasum, Ellen. Oxygen cost of E-C coupling in the diabetic heart. Kardiologisk vintermøte 2008-02-01 - 2008-02-03 2008.
  • Jonassen, Anne K.; Wiig, Helge; Boardman, Neoma Tove. Evaluation of the effect of direct activation of p70s6 kinase on cell survival after ischemic-reperfusion. 2006.
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    Forskningsinteresser

    Heart failure remains a leading cause of death in Norway and worldwide, and despite improved treatment strategies, its prognosis is bleak and quality of life is reduced.  The overall theme of current projects include the contribution of metabolic disease and hypertension to the development of cardiac disease and its progression to heart failure.  At the center of this work are the mitochondria, widely investigated for their role in metabolism, energy production, and in regulation of cell survival systems. This emerging field holds potential for novel therapeutic treatments for cardiovascular diseases. Our goal is translational science and we use an integrated approach of physiology, biochemistry, and advanced imaging to elucidate our research questions.

    Undervisning

    Underviser i humanfysiologi og vitenskapelige metoder for helsefag studenter og studenter i biomedisin.




    MH L7.221 B