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Institutt for medisinsk biologi neoma.boardman@uit.no +4777644681 Tromsø MH L7.221 B

Neoma Tove Boardman


Førsteamanuensis

Stillingsbeskrivelse

1.amanuensis


  • Synne Hansen, Tina Myhre Pedersen, Julie Marin, Neoma Tove Boardman, Ajay M. Shah, Ellen Aasum, Anne Dragøy Hafstad:
    Overexpression of NOX2 Exacerbates AngII‐Mediated Cardiac Dysfunction and Metabolic Remodelling
    Antioxidants 2022 Ekstern lenke
  • Neoma Tove Boardman, Tina Myhre Pedersen, Line Rossvoll, Anne Dragøy Hafstad, Ellen Aasum:
    Diet-induced obese mouse hearts tolerate an acute high fatty acid exposure that also increases ischemic tolerance
    American Journal of Physiology. Heart and Circulatory Physiology 2020 Ekstern lenke
  • Anne Dragøy Hafstad, Synne Simonsen Hansen, Jim Lund, Celio X.C. Santos, Neoma Tove Boardman, Ajay M. Shah, Ellen Aasum:
    NADPH oxidase 2 mediates myocardial oxygen wasting in obesity
    Antioxidants 2020 Ekstern lenke
  • Neoma Tove Boardman, Baher Migally, Chantal Pileggi, Gaganwir S. Parmar, Jian Ying Xuan, Keir Menzies, Mary-Ellen Harper:
    Glutaredoxin-2 and Sirtuin-3 deficiencies impair cardiac mitochondrial energetics but their effects are not additive
    Biochimica et Biophysica Acta - Molecular Basis of Disease 24. september 2020 Ekstern lenke
  • Marina Makrecka-Kuka, Edgars Liepinsh, Andrew J. Murray, Hélène Lemieux, Maija Dambrova, Kersti Tepp, Marju Puurand, Tuuli Käämbre, Woo H. Han, Paul de Goede, Katie A. O'Brien, Belma Turan, Erkan Tuncay, Yusuf Olgar, Anabela P. Rolo, Carlos M. Palmeira, Neoma Tove Boardman, Rob C.I. Wüst, Terje Larsen:
    Altered mitochondrial metabolism in the insulin-resistant heart
    Acta Physiologica 2019 Ekstern lenke
  • Neoma Tove Boardman, Line Rossvoll, Jim Lund, Anne Dragøy Hafstad, Ellen Aasum:
    3-Weeks of Exercise Training Increases Ischemic-Tolerance in Hearts From High-Fat Diet Fed Mice
    Frontiers in Physiology 02. oktober 2019 Ekstern lenke
  • Neoma Tove Boardman, Aleksander Tank Falck, Trine Lund, Xi Chu, Armas Maria Montserrat Martin, Jon Viljar Norvik, Trond Geir Jenssen, Kirsti Ytrehus:
    Human concentrations of uric acid scavenges adaptive and maladaptive ROS in isolated rat hearts subjected to ischemic stress
    Canadian Journal of Physiology and Pharmacology 13. september 2019 Ekstern lenke
  • Tina Myhre Pedersen, Neoma Boardman, Anne Dragøy Hafstad, Ellen Aasum:
    Isolated perfused working hearts provide valuable additional information during phenotypic assessment of the diabetic mouse heart
    PLOS ONE 2018 Ekstern lenke
  • Neoma Boardman, Anne Dragøy Hafstad, Jim Lund, Line Rossvoll, Ellen Aasum:
    Exercise of obese mice induces cardioprotection and oxygen sparing in hearts exposed to high-fat load
    American Journal of Physiology. Heart and Circulatory Physiology 2017 Ekstern lenke
  • Jim Lund, Anne Dragøy Hafstad, Neoma Tove Boardman, Line Rossvoll, Natale Pinheiro Lage Rolim, Muhammad Shakil Ahmed, Geir Florholmen, Håvard Attramadal, Ulrik Wisløff, Terje Larsen, Ellen Aasum:
    Exercise training promotes cardioprotection through oxygen-sparing action in high fat-fed mice
    American Journal of Physiology. Heart and Circulatory Physiology 2015 Ekstern lenke
  • Jens Petter Bakkehaug, Anders Benjamin Kildal, Erik Torgersen Engstad, Neoma Tove Boardman, Torvind Næsheim, Leif R. Rønning, Ellen Aasum, Terje Larsen, Truls Myrmel, Ole-Jakob How:
    Myosin activator omecamtiv mecarbil increases myocardial oxygen consumption and impairs cardiac efficiency mediated by resting myosin ATPase activity
    Circulation: Heart Failure 2015 Ekstern lenke
  • Anne Dragøy Hafstad, Neoma Tove Boardman, Ellen Aasum:
    How Exercise May Amend Metabolic Disturbances in Diabetic Cardiomyopathy
    Antioxidants and Redox Signaling 2015 Ekstern lenke
  • Neoma Tove Boardman, Jan Magnus Aronsen, William Edward Louch, Ivar Sjaastad, Frode Willoch, Geir Arve Christensen, Ole M Sejersted, Ellen Aasum:
    Impaired left ventricular mechanical and energetic function in mice after cardiomyocyte-specific excision of Serca2
    American Journal of Physiology. Heart and Circulatory Physiology 2014 Ekstern lenke
  • Neoma Tove Boardman, Jan Magnus Aronsen, William Edward Louch, Ivar Sjaastad, Frode Willoch, Geir Arve Christensen, Ole M Sejersted, Ellen Aasum:
    Impaired left ventricular mechanical and energetic function in mice after cardiomyocyte-specific excision of Serca2
    American Journal of Physiology. Heart and Circulatory Physiology 2014 Ekstern lenke
  • Neoma Tove Boardman, Terje Larsen, david lester Severson, M Fadiel Essop, Ellen Aasum:
    Chronic and acute exposure of mouse hearts to fatty acids increases oxygen cost of excitation-contraction coupling
    American Journal of Physiology. Heart and Circulatory Physiology 2011 Ekstern lenke
  • Ahmed Murtaz Khalid, Anne Dragøy Hafstad, Terje Larsen, david lester Severson, Neoma Tove Boardman, Martin Hagve, Rolf Kristian Berge, Ellen Aasum:
    Cardioprotective effect of the PPAR ligand tetradecylthioacetic acid in type 2 diabetic mice
    American Journal of Physiology. Heart and Circulatory Physiology 2011 Ekstern lenke
  • Anne Dragøy Hafstad, Neoma Tove Boardman, Jim Lund, Martin Hagve, Ahmed Murtaz Khalid, Ulrik Wisløff, Terje Larsen, Ellen Aasum:
    High intensity interval training alters substrate utilization and reduces oxygen consumption in the heart
    Journal of applied physiology 2011 Ekstern lenke
  • Neoma Tove Boardman, Anne Dragøy Hafstad, Terje Larsen, DL Severson, Ellen Aasum:
    Increased O-2 cost of basal metabolism and excitation-contraction coupling in hearts from type 2 diabetic mice
    American Journal of Physiology. Heart and Circulatory Physiology 2009 Ekstern lenke
  • Ole-Jakob How, Terje Larsen, Anne Dragøy Hafstad, Ahmed Murtaz Khalid, Eivind S. P. Myhre, AJ Myrray, Neoma Boardman, M Cole, Kieran Clarke, David Lester Severson, Ellen Aasum:
    Rosiglitazone treatment improves cardiac efficiency in hearts from diabetic mice
    Archives of Physiology and Biochemistry 2007
  • Neoma Tove Boardman:
    Harnessing the protective role of OPA-1 in diabetic cardiomyopathy
    Acta Physiologica 2020 Ekstern lenke
  • Kirsti Ytrehus, Neoma Tove Boardman, trine Lund, Svetlana Zykova, Trond Geir Jenssen:
    The uric acid paradox, a confounder in cardiovascular research and experimental studies of cardioprotection
    Conditioning Medicine 2019
  • Jens Petter Bakkehaug, Anders Benjamin Kildal, Erik Torgersen Engstad, Neoma Tove Boardman, Torvind Næsheim, Leif R. Rønning, Ellen Aasum, Terje Larsen, Truls Myrmel, Ole-Jakob How:
    Response to Letter Regarding Article, "Myosin Activator Omecamtiv Mecarbil Increases Myocardial Oxygen Consumption and Impairs Cardiac Efficiency Mediated by Resting Myosin ATPase Activity"
    Circulation: Heart Failure 2015 Ekstern lenke
  • Neoma Tove Boardman, Ellen Aasum (Veileder):
    Cardiometabolic adaptations to altered fuel supply, Ca2+ handling and exercise
    2011
  • Anne Dragøy Hafstad, Neoma Tove Boardman, Jim Lund, Martin Hagve, Ulrik Wisløff, Terje Larsen, Ellen Aasum:
    Metabolic adaptations in the physiologically hypertrophied heart
    2009
  • Anne Dragøy Hafstad, Neoma Tove Boardman, Jim Lund, Martin Hagve, Ulrik Wisløff, Terje Larsen, Ellen Aasum:
    Exercise-induced Increase In Cardiac Efficiency - The Impact of Intensity
    2009
  • Anne Dragøy Hafstad, Neoma Tove Boardman, Jim Lund, Martin Hagve, Ulrik Wisløff, Terje Larsen, Ellen Aasum:
    Exercise-induced Increase In Cardiac Efficiency - The Impact of Intensity
    Circulation 2009
  • Neoma Tove Boardman, Anne Dragøy Hafstad, Terje Larsen, david lester Severson, Ellen Aasum:
    The O2 cost of basal metabolism and excitation-contraction coupling is increased in hearts from type 2 diabetic mice
    2008
  • Anne Dragøy Hafstad, Ahmed Murtaz Khalid, Neoma Tove Boardman, Terje Larsen, Ellen Aasum:
    The pan ppar ligand tta has a direct cardiometabolic effect in normal and diabetic mice
    2008
  • Neoma Tove Boardman, Anne Dragøy Hafstad, Terje Larsen, david lester Severson, Ellen Aasum:
    Oxygen cost of E-C coupling in the diabetic heart
    Hjerteforum 2008
  • Neoma Tove Boardman, Anne Dragøy Hafstad, Terje Larsen, david lester Severson, Ellen Aasum:
    Oxygen cost of E-C coupling in the diabetic heart
    2008
  • Anne K. Jonassen (Veileder), Helge Wiig (Veileder), Neoma Tove Boardman:
    Evaluation of the effect of direct activation of p70s6 kinase on cell survival after ischemic-reperfusion
    2006
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    Forskningsinteresser

    Heart failure remains a leading cause of death in Norway and worldwide, and despite improved treatment strategies, its prognosis is bleak and quality of life is reduced.  The overall theme of current projects include the contribution of metabolic disease and hypertension to the development of cardiac disease and its progression to heart failure.  At the center of this work are the mitochondria, widely investigated for their role in metabolism, energy production, and in regulation of cell survival systems. This emerging field holds potential for novel therapeutic treatments for cardiovascular diseases. Our goal is translational science and we use an integrated approach of physiology, biochemistry, and advanced imaging to elucidate our research questions.

    Undervisning

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    MH L7.221 B