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Institutt for medisinsk biologi anne.hafstad@uit.no +4777625183 Tromsø MH L7.225C

Anne Dragøy Hafstad


Førsteamanuensis


  • Lisa C. Heather, Anne Dragøy Hafstad, Ganesh V. Halade, Romain Harmancey, Kimberley M. Mellor, Paras K. Mishra, Erin E. Mulvihill, Miranda Nabben, Michinari Nakamura, Oliver J. Rider, Matthieu Ruiz, Adam R. Wende, John R. Ussher:
    Guidelines on models of diabetic heart disease
    American Journal of Physiology. Heart and Circulatory Physiology 2022 Ekstern lenke
  • Synne Hansen, Tina Myhre Pedersen, Julie Marin, Neoma Tove Boardman, Ajay M. Shah, Ellen Aasum, Anne Dragøy Hafstad:
    Overexpression of NOX2 Exacerbates AngII‐Mediated Cardiac Dysfunction and Metabolic Remodelling
    Antioxidants 2022 Ekstern lenke
  • Matteo Beretta, Celio X.C. Santos, Chris Molenaar, Anne Dragøy Hafstad, Chris CJ Miller, Aram Revazian, Kai Betteridge, Katrin Schröder, Katrin Streckfuß-Bömeke, James H Doroshow, Roland A Fleck, Tsung-Ping Su, Vsevelod Belousov, Maddy Parsons, Ajay M. Shah:
    Nox4 regulates InsP3 receptor‐dependent Ca2+ release into mitochondria to promote cell survival
    EMBO Journal 2020 Ekstern lenke
  • Neoma Tove Boardman, Tina Myhre Pedersen, Line Rossvoll, Anne Dragøy Hafstad, Ellen Aasum:
    Diet-induced obese mouse hearts tolerate an acute high fatty acid exposure that also increases ischemic tolerance
    American Journal of Physiology. Heart and Circulatory Physiology 2020 Ekstern lenke
  • Anne Dragøy Hafstad, Synne Simonsen Hansen, Jim Lund, Celio X.C. Santos, Neoma Tove Boardman, Ajay M. Shah, Ellen Aasum:
    NADPH oxidase 2 mediates myocardial oxygen wasting in obesity
    Antioxidants 2020 Ekstern lenke
  • Neoma Tove Boardman, Line Rossvoll, Jim Lund, Anne Dragøy Hafstad, Ellen Aasum:
    3-Weeks of Exercise Training Increases Ischemic-Tolerance in Hearts From High-Fat Diet Fed Mice
    Frontiers in Physiology 02. oktober 2019 Ekstern lenke
  • Tina Myhre Pedersen, Neoma Boardman, Anne Dragøy Hafstad, Ellen Aasum:
    Isolated perfused working hearts provide valuable additional information during phenotypic assessment of the diabetic mouse heart
    PLOS ONE 2018 Ekstern lenke
  • Matthew Hancock, Anne Dragøy Hafstad, Adam A. Nabeebaccus, Norman Catibog, Angela Logan, Ioannis Smyrnias, Synne Simonsen Hansen, Johanna Lanner, Katrin Schröder, Michael P. Murphy, Ajay M. Shah, Min Zhang:
    Myocardial NADPH oxidase-4 regulates the physiological response to acute exercise
    eLIFE 2018 Ekstern lenke
  • Synne Simonsen Hansen, Ellen Aasum, Anne Dragøy Hafstad:
    The role of NADPH oxidases in diabetic cardiomyopathy
    Biochimica et Biophysica Acta - Molecular Basis of Disease 2018 Ekstern lenke
  • Adam A. Nabeebaccus, Anna Zoccarato, Anne Dragøy Hafstad, Celio X.C. Santos, Ellen Aasum, Alison C. Brewer, Min Zhang, Matteo Beretta, Xiaoke Yin, James A. West, Katrin Schröder, Julian L. Griffin, Thomas R. Eykyn, Abel Dale Abel, Manuel Mayr, Ajay M. Shah:
    Nox4 reprograms cardiac substrate metabolism via protein O-GlcNAcylation to enhance stress adaptation
    JCI Insight 2017 Ekstern lenke
  • Neoma Boardman, Anne Dragøy Hafstad, Jim Lund, Line Rossvoll, Ellen Aasum:
    Exercise of obese mice induces cardioprotection and oxygen sparing in hearts exposed to high-fat load
    American Journal of Physiology. Heart and Circulatory Physiology 2017 Ekstern lenke
  • Celio X.C. Santos, Anne Dragøy Hafstad, Matteo Beretta, Min Zhang, Chris Molenaar, Jola Kopec, Dina Fotinou, Thomas V. Murray, Andrew M. Cobb, Daniel Martin, Maira Zeh Silva, Narayana Anilkumar, Katrin Schröder, Catherine M. Shanahan, Alison C. Brewer, Ralf P. Brandes, Eric Blanc, Maddy Parsons, Vsevelod Belousov, Richard Cammack, Robert C. Hider, Roberto A. Steiner, Ajay M. Shah:
    Targeted redox inhibition of protein phosphatase 1 by Nox4 regulates eIF2α-mediated stress signaling
    EMBO Journal 2016 Ekstern lenke
  • Elin Synnøve Hadler-Olsen, Ann Iren Solli, Anne Dragøy Hafstad, Jan-Olof Winberg, Lars Uhlin-Hansen:
    Intracellular MMP-2 Activity in Skeletal Muscle is Associated with Type II Fibers
    Journal of Cellular Physiology 2015 Ekstern lenke
  • Jim Lund, Anne Dragøy Hafstad, Neoma Tove Boardman, Line Rossvoll, Natale Pinheiro Lage Rolim, Muhammad Shakil Ahmed, Geir Florholmen, Håvard Attramadal, Ulrik Wisløff, Terje Larsen, Ellen Aasum:
    Exercise training promotes cardioprotection through oxygen-sparing action in high fat-fed mice
    American Journal of Physiology. Heart and Circulatory Physiology 2015 Ekstern lenke
  • Anne Dragøy Hafstad, Neoma Tove Boardman, Ellen Aasum:
    How Exercise May Amend Metabolic Disturbances in Diabetic Cardiomyopathy
    Antioxidants and Redox Signaling 2015 Ekstern lenke
  • Nils Thomas Songstad, Knut-Helge Kaspersen, Anne Dragøy Hafstad, Purusotam Basnet, Kirsti Ytrehus, Ganesh Acharya:
    Effects of high intensity interval training on pregnant rats, and the placenta, heart and liver of their fetuses
    PLOS ONE 13. november 2015 Ekstern lenke
  • Anje Christina Höper, Wahida Salma, Selene Julie Sollie, Anne Dragøy Hafstad, Jim Lund, Ahmed Murtaz Khalid, Jan Raa, Ellen Aasum, Terje Larsen:
    Wax esters from the marine copepod calanus finmarchicus reduce diet-induced obesity and obesity-related metabolic disorders in mice
    Journal of Nutrition 2014 Ekstern lenke
  • Anje Christina Höper, Wahida Salma, Ahmed Murtaz Khalid, Anne Dragøy Hafstad, Selene Julie Sollie, Jan Raa, Terje Larsen, Ellen Aasum:
    Oil from the marine zooplankton Calanus finmarchicus improves the cardiometabolic phenotype of diet-induced obese mice
    British Journal of Nutrition 2013 Ekstern lenke
  • Anne Dragøy Hafstad, Jim Lund, Elin Synnøve Hadler-Olsen, Anje Christina Höper, Terje Larsen, Ellen Aasum:
    High- and Moderate-Intensity Training Normalizes Ventricular Function and Mechanoenergetics hi Mice With Diet-Induced Obesity
    Diabetes 2013 Ekstern lenke
  • Anne Dragøy Hafstad, Adam Nabeebaccus, Ajay Shah:
    Novel aspects of ROS signalling in heart failure
    Basic Research in Cardiology 2013 Ekstern lenke
  • Ahmed Murtaz Khalid, Anne Dragøy Hafstad, Terje Larsen, david lester Severson, Neoma Tove Boardman, Martin Hagve, Rolf Kristian Berge, Ellen Aasum:
    Cardioprotective effect of the PPAR ligand tetradecylthioacetic acid in type 2 diabetic mice
    American Journal of Physiology. Heart and Circulatory Physiology 2011 Ekstern lenke
  • Anne Dragøy Hafstad, Neoma Tove Boardman, Jim Lund, Martin Hagve, Ahmed Murtaz Khalid, Ulrik Wisløff, Terje Larsen, Ellen Aasum:
    High intensity interval training alters substrate utilization and reduces oxygen consumption in the heart
    Journal of applied physiology 2011 Ekstern lenke
  • Neoma Tove Boardman, Anne Dragøy Hafstad, Terje Larsen, DL Severson, Ellen Aasum:
    Increased O-2 cost of basal metabolism and excitation-contraction coupling in hearts from type 2 diabetic mice
    American Journal of Physiology. Heart and Circulatory Physiology 2009 Ekstern lenke
  • Anne Dragøy Hafstad, Ahmed Murtaz Khalid, Martin Hagve, trine Lund, Terje Larsen, DL Severson, Kieran Clarke, Rolf Berge, Ellen Aasum:
    Cardiac peroxisome proliferator-activated receptor-alpha activation causes increased fatty acid oxidation, reducing efficiency and post-ischaemic functional loss
    Cardiovascular Research (CVR) 2009 Ekstern lenke
  • Kåre-Olav Stensløkken, Arkady Rutkovskiy, Mari-Liis Kaljusto, Anne Dragøy Hafstad, Terje Larsen, Jarle Vaage:
    Inadvertent phosphorylation of survival kinases in isolated perfused hearts: a word of caution
    Basic Research in Cardiology 2009 Ekstern lenke
  • Anne Dragøy Hafstad, Ahmed Murtaz Khalid, Ole-Jakob How, Terje Larsen, Ellen Aasum:
    Glucose and insulin improve cardiac efficiency and postischemic functional recovery in perfused hearts from type 2 diabetic (db/db) mice
    American Journal of Physiology. Endocrinology and Metabolism 2007 Ekstern lenke
  • Ole-Jakob How, Terje Larsen, Anne Dragøy Hafstad, Ahmed Murtaz Khalid, Eivind S. P. Myhre, AJ Myrray, Neoma Boardman, M Cole, Kieran Clarke, David Lester Severson, Ellen Aasum:
    Rosiglitazone treatment improves cardiac efficiency in hearts from diabetic mice
    Archives of Physiology and Biochemistry 2007
  • Anne Dragøy Hafstad, Geir Helge Solevåg, david lester Severson, Terje Larsen, Ellen Aasum:
    Perfused hearts from type 2 diabetic (db/db) mice show metabolic responsiveness to insulin
    American Journal of Physiology. Heart and Circulatory Physiology 2006
  • Ellen Aasum, Anne Dragøy Hafstad, David Lester Severson, Terje Larsen:
    Cardiac Age-dependent changes in metabolism, contractile function and ischemic sensitivity in hearts from db/db mice
    Diabetes 2003
  • Ellen Aasum, Anne Dragøy Hafstad, Terje Larsen:
    Changes in substrate metabolism in isolated mouse hearts following ischemia-reperfusion
    Molecular and Cellular Biochemistry 2003
  • Anne Dragøy Hafstad, Astri Jeanette Meen:
    Trenger frivillige til forskning på smartplaster
    12. mai 2021 Ekstern lenke
  • Anne Dragøy Hafstad:
    Flere har meldt seg til å teste dette plasteret - kan gi ny helt ny kunnskap
    20. mai 2021 Ekstern lenke
  • Anne Dragøy Hafstad, Ellen Aasum, Jim Lund, Santos Celio X, Ajay Shah:
    A role of NADPH oxidase in obesity-induced myocardial oxygen wasting
    2015
  • Anne Dragøy Hafstad, Jim Lund, Ellen Aasum, Celio X Santos, Ajay Shah:
    A role of NADPH oxidase in obesity-induced myocardial oxygen wasting
    2014
  • Anne Dragøy Hafstad:
    Positive effekter av trening på hjertets forbrenning ved fedme og diabetes
    2014
  • Anne Dragøy Hafstad:
    Hjertegod trening ved fedme og diabetes
    2014
  • Anne Dragøy Hafstad:
    Trening normaliserte hjertefunksjonen hos overvektige mus
  • Anne Dragøy Hafstad:
    Hjertegod trening av feite mus
    2013
  • Anne Dragøy Hafstad, Jim Lund, Ellen Aasum, C Santos, Ajay Shah:
    Prevention of obesity-induced myocardial oxygen-wasting through NADPH-oxidase inhibition
    2013
  • Elin Synnøve Hadler-Olsen, Ann Iren Solli, Anne Dragøy Hafstad, Jan-Olof Winberg, Lars Uhlin-Hansen:
    Intracellular MMP-2 Activity in Skeletal Muscle is Associated with Type II Fibers
    2013
  • Jim Lund, Anne Dragøy Hafstad, Terje Larsen, Ellen Aasum:
    High and moderate intensity training prevent obesity-related oxygen waste and development of left ventricular dysfunction in the presence of high fat
    2012
  • Anne Dragøy Hafstad, Jim Lund, Terje Larsen, Ellen Aasum:
    Cardiovascular Research Group, Faculty of Health Sciences, University of Tromsø, Norway. Exercise training prevent obesity-induced impairment of myocardial function and mechanoenergetics, as well as mitochondrial capacity and fatty acid-induced proton leak
    2012
  • Nils Thomas Songstad, Knut-Helge Kaspersen, Anne Dragøy Hafstad, Ganesh Acharya:
    Høyintesitets intervalltrening hos gravide rotter
    2012
  • Knut-Helge Kaspersen, Nils Thomas Songstad, Anne Dragøy Hafstad, Ganesh Acharya:
    High intensity training in pregnant rats
    2012
  • Anje Christina Höper, Terje Larsen, Ahmed Murtaz Khalid, Wahida Salma, Selene Julie Sollie, Jim Lund, Anne Dragøy Hafstad, Ellen Aasum:
    Low-dose supplementation with Calanus oil attenuates visceral adiposity and low-grade inflammation during high fat feeding
    2012
  • Wahida Salma, Anje Christina Höper, Ahmed Murtaz Khalid, Selene Julie Sollie, Jim Lund, Anne Dragøy Hafstad, Ellen Aasum, Terje Larsen:
    Wax ester purified from Calanus oil reduces visceral obesity and low-grade inflammation in adipose tissue during high fat feeding
    2012
  • Wahida Salma, Selene Julie Sollie, Anje Christina Höper, Ahmed Murtaz Khalid, Jim Lund, Anne Dragøy Hafstad, Terje Larsen, Ellen Aasum:
    Dietary supplementation with Calanus oil reduces visceral fat deposition and improves insulin sensitivity during high fat feeding
    2012
  • Anne Dragøy Hafstad, Jim Lund, Martin Hagve, Elin Synnøve Hadler-Olsen, Anje Christina Höper, Terje Larsen, Ellen Aasum:
    High and moderate intensity training prevent diet-induced impairments in cardiac mechanoenergetics and ventricular function
    2012
  • Anne Dragøy Hafstad, Jim Lund, Anje Christina Høper, Elin Synnøve Hadler-Olsen, Martin Hagve, Ulrik Wisløff, Terje Larsen, Ellen Aasum:
    Exercise improves ventricular function and decreases myocardial oxygen waste in diet-induced obese mice
    2011
  • Anne Dragøy Hafstad, Jim Lund, Anje Christina Høper, Elin Synnøve Hadler-Olsen, Martin Hagve, Ulrik Wisløff, Terje Larsen, Ellen Aasum:
    Exercise improves ventricular function and decreases myocardial oxygen waste in diet-induced obese mice
    Circulation 2011
  • Anje Christina Høper, Terje Larsen, Jim Lund, Anne Dragøy Hafstad, Ahmed Murtaz Khalid, Ellen Aasum:
    Oil extracted from the marine copepod Calanus finmarchicus reduces diet-induced obesity and insulin resistance, and improves aerobic capacity in mice
    2011
  • Anne Dragøy Hafstad, Jim Lund, Anje Christina Høper, Elin Synnøve Hadler-Olsen, Martin Hagve, Ulrik Wisløff, Terje Larsen, Ellen Aasum:
    High intensity interval training normalizes cardiac energetics and ventricular function in diet-induced obese mice
    2011
  • Anne Dragøy Hafstad, Neoma Tove Boardman, Jim Lund, Martin Hagve, Ulrik Wisløff, Terje Larsen, Ellen Aasum:
    Metabolic adaptations in the physiologically hypertrophied heart
    2009
  • Ellen Aasum, Anne Dragøy Hafstad, Ahmed Murtaz Khalid, Rolf Berge, Terje Larsen:
    TTA - the first PPAR ligand shown to increase fatty acid oxidation in normal and diabetic myocardium when administered in vivo
    2009
  • Anne Dragøy Hafstad, Neoma Tove Boardman, Jim Lund, Martin Hagve, Ulrik Wisløff, Terje Larsen, Ellen Aasum:
    Exercise-induced Increase In Cardiac Efficiency - The Impact of Intensity
    2009
  • Anne Dragøy Hafstad, Neoma Tove Boardman, Jim Lund, Martin Hagve, Ulrik Wisløff, Terje Larsen, Ellen Aasum:
    Exercise-induced Increase In Cardiac Efficiency - The Impact of Intensity
    Circulation 2009
  • Neoma Tove Boardman, Anne Dragøy Hafstad, Terje Larsen, david lester Severson, Ellen Aasum:
    The O2 cost of basal metabolism and excitation-contraction coupling is increased in hearts from type 2 diabetic mice
    2008
  • Anne Dragøy Hafstad, Ahmed Murtaz Khalid, Neoma Tove Boardman, Terje Larsen, Ellen Aasum:
    The pan ppar ligand tta has a direct cardiometabolic effect in normal and diabetic mice
    2008
  • Ahmed Murtaz Khalid, Anne Dragøy Hafstad, trine Lund, Terje Larsen, david lester Severson, Rolf Berge, Kieran Clarke, Ellen Aasum:
    Administration of tetradecylthioacetic acid (TTA) in mice accelerates myocardial FA oxidation via increased expression of pparα target genes
    Hjerteforum 2008
  • Neoma Tove Boardman, Anne Dragøy Hafstad, Terje Larsen, david lester Severson, Ellen Aasum:
    Oxygen cost of E-C coupling in the diabetic heart
    Hjerteforum 2008
  • KO Stenslokken, A Rutkovsky, ML Kaijusto, Anne Dragøy Hafstad, Terje Larsen, J Vaage:
    Degree of phosphorylation of survival kinases in isolated mouse hearts depends on the mode of perfusion
    Journal of Molecular and Cellular Cardiology 2008 Ekstern lenke
  • Ahmed Murtaz Khalid, Ellen Aasum, Anne Dragøy Hafstad, K Clarke, Rolf Berge, Terje Larsen:
    TTA is a pan PPAR ligand which markedly stimulates fatty acid oxidation following in vivo administration
    Cardiovascular Drugs and Therapy 2008
  • Ahmed Murtaz Khalid, Ellen Aasum, Anne Dragøy Hafstad, Terje Larsen:
    Reduced lipid supply without a concomitant reduced glucose supply fails to alter the metabolic phenotype of diabetic hearts
    Journal of Molecular and Cellular Cardiology 2008 Ekstern lenke
  • Ahmed Murtaz Khalid, Anne Dragøy Hafstad, trine Lund, Terje Larsen, david lester Severson, Rolf Berge, Kieran Clarke, Ellen Aasum:
    Administration of tetradecylthioacetic acid (TTA) in mice accelerates myocardial FA oxidation via increased expression of pparα target genes
    2008
  • Neoma Tove Boardman, Anne Dragøy Hafstad, Terje Larsen, david lester Severson, Ellen Aasum:
    Oxygen cost of E-C coupling in the diabetic heart
    2008
  • Anne Dragøy Hafstad, Ahmed Murtaz Khalid, Ole-Jakob How, Rolf Berge, Terje Larsen, Ellen Aasum:
    In vivo administration of tetradecylthioacetic acid (TTA) in mice causes cardiac inefficiency and reduced post-ischemic ventricular function
    2007
  • Ahmed Murtaz Khalid, Ellen Aasum, Anne Dragøy Hafstad, Kieran Clarke, Rolf Berge, Terje Larsen:
    TTA is a pan PPAR ligand which markedly stimulates fatty acid oxidation following in vivo administration
    2007
  • Anne Dragøy Hafstad, Ahmed Murtaz Khalid, Ole-Jakob How, Terje Larsen, Ellen Aasum:
    Glucose and insulin improve energy metabolism, efficiency and ischemic tolerance in hearts from type 2 diabetic mice
    2007
  • Anne Dragøy Hafstad, Ahmed Murtaz Khalid, Ole-Jakob How, Rolf Berge, Terje Larsen, Ellen Aasum:
    In vivo administration of tetradecylthioacetic acid (TTA) in mice causes cardiac inefficiency and reduced post-ischemic ventricular function
    Journal of Molecular and Cellular Cardiology 2007 Ekstern lenke
  • Thomas Stølen, Ole J. Kemi, Morten A. Høydal, Anja Bye, Arnt E. Tjonna, Anne Dragøy Hafstad, Terje Larsen, Godfrey L. Smith, Ulrik Wisløff:
    Reversed Ryr-leakage And Improved Contractile Function In Cardiomyocytes From Type-2 Diabetic Heart After Exercise Training
    Medicine & Science in Sports & Exercise 2007
  • Anne Dragøy Hafstad, Ellen Aasum (Veileder):
    Metabolic modulation of the diabetic heart – Its impact on cardiac efficiency and ischemic tolerance. A study on substrate metabolism, contractile function and efficiency in isolated working mouse hearts
    2007
  • Thomas Stølen, Ole J. Kemi, Morten A. Høydal, Anja Bye, Anne Dragøy Hafstad, Terje Larsen, Godfrey L. Smith, Ulrik Wisløff:
    Reversed RyR-leakage and improved contractile function in cardiomyocytes from type-2 diabetic heart after exercise training
    2007
  • Anne Dragøy Hafstad:
    Impact of cardiac metabolism efficiency and ischemic tolerance
    2007
  • Ole-Jakob How, Terje Larsen, Anne Dragøy Hafstad, Ahmed Murtaz Khalid, Eivind S. P. Myhre, david lester Severson, Ellen Aasum:
    Rosiglitazone improves cardiac efficiency and recovery of ventricular function following ischemia in hearts from type 2 diabetic mice
    2006
  • Anne Dragøy Hafstad, Ahmed Murtaz Khalid, Ole-Jakob How, Terje Larsen, Ellen Aasum:
    Elevated glucose and insulin improve cardiac efficiency and post-ischemic functional recovery in perfused hearts from type 2 diabetic (db/db) mice
    2006
  • Ole-Jakob How, Terje Larsen, Anne Dragøy Hafstad, Ahmed Murtaz Khalid, Eivind S. P. Myhre, david lester Severson, Ellen Aasum:
    Rosiglitazone treatment improves cardiac efficiency and post-ischemic functional recovery in hearts from diabetic mice
    2006
  • Ellen Aasum, Anne Dragøy Hafstad, Ole-Jakob How, Ahmed Murtaz Khalid, david lester Severson, Terje Larsen:
    Chronic and acute metabolic interventions improve cardiac metabolism and enhances cardiac efficiency and ischemic tolerance in type 2 diabetes
    Circulation 2006
  • Ellen Aasum, Anne Dragøy Hafstad, Ole-Jakob How, Ahmed Murtaz Khalid, Terje Larsen:
    Improved cardiac metabolism enhances cardiac efficiency and ischemic tolerance in type 2 diabetes
    Circulation 2006
  • Ole-Jakob How, Terje Larsen, Anne Dragøy Hafstad, Ahmed Murtaz Khalid, Eivind S. P. Myhre, david lester Severson, Ellen Aasum:
    Rosiglitazone treatment improves cardiac efficiency and post-ischemic functional recovery in hearts from diabetic mice
    Cardiovascular Drugs and Therapy 2006
  • Anne Dragøy Hafstad, Ahmed Murtaz Khalid, Ole-Jakob How, Terje Larsen, Ellen Aasum:
    Elevated glucose and insulin improves cardiac efficiency and post-ischemic functional recovery in perfused hearts from type 2 diabetic (db/db) mice
    Cardiovascular Drugs and Therapy 2006
  • Anne Dragøy Hafstad, Ahmed Murtaz Khalid, Ole-Jakob How, Terje Larsen, Ellen Aasum:
    Changing myocardial energy utilization from fat to glucose improves post-ischemic recovery in hearts from type 2 diabetic (db/db) mice
    Journal of Molecular and Cellular Cardiology 2006
  • Anne Dragøy Hafstad, Ahmed Murtaz Khalid, Ole-Jakob How, Terje Larsen, Ellen Aasum:
    The type 2 diabetic heart is not an insulin resistant organ
    2006
  • Anne Dragøy Hafstad, Ahmed Murtaz Khalid, Ole-Jakob How, Terje Larsen, Ellen Aasum:
    Changing myocardial energy utilization from fat to glucose improves post-ischemic recovery in hearts from type 2 diabetic (db/db) mice
    2006
  • Thomas Stølen, Ole J. Kemi, Morten A. Høydal, Anja Bye, Arnt E. Tjonna, Anne Dragøy Hafstad, Terje Larsen, Godfrey L. Smith, Ulrik Wisløff:
    Reversed RyR-leakage And Improved Contractile Function In Cardiomyocytes From Type-2 Diabetic Heart After Exercise Training
    2006
  • Ellen Aasum, Anne Dragøy Hafstad, Ole-Jakob How, Ahmed Murtaz Khalid, david lester Severson, Terje Larsen:
    Chronic and acute metabolic interventions improve cardiac metabolism and enhances cardiac efficiency and ischemic tolerance in type 2 diabetes
    2006
  • Marit Arianne Vader, Faadiel Essop, Anne Dragøy Hafstad, Terje Larsen, Ellen Aasum:
    Acute effects of ppar ligands on cardiac metabolism
    01. januar 2005
  • Anne Dragøy Hafstad:
    Insulin sensitivity in hearts from type 2 diabetic (db/db) mice
    Hjerteforum 2005
  • Marit Arianne Vader, M Fadiel Essop, Anne Dragøy Hafstad, Terje Larsen, Ellen Aasum:
    Acute effects of ppar ligands on cardiac metabolism
    Journal of Molecular and Cellular Cardiology 2005
  • Anne Dragøy Hafstad:
    Insulin sensitivity in hearts from type 2 diabetic (db/db) mice
    2005
  • Anne Dragøy Hafstad, David Lester Severson, Terje Larsen, Ellen Aasum:
    Hearts from type 2 diabetic (db/db) are highly sensitive to insulin
    01. januar 2003
  • Se alle arbeider i Cristin →

    Publikasjoner utenom Cristin

    A. A. Nabeebaccus, A. Zoccarato, A. D. Hafstad, C. X.C. Santos, E. Aasum, A. C. Brewer, M. Zhang, M. Beretta, X. Yin, J. A. West, K. Schröder, J. L. Griffin, T. R. Eykyn, E. D Abel, M. Mayr, and A. M. Shah. Nox4 reprograms cardiac substrate metabolism via protein O-GlcNAcylation to enhance stress adaptation. Journal of Clinical Investigation (JCI) Insight. 2018. Ahead of print.

     

    Hafstad. AD. NADPH oksidaser i diabetisk hjertesykdom BestPractise. Diabetes/Hjerte-Kar sykdommer. 2018. Review. Ahead of print.

     

    S.S. Hansen, E. Aasum, A.D. Hafstad, The role of NADPH oxidases in diabetic cardiomyopathy, Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease, (2017). Review. Ahead of print

     

    N.T. Boardman, A.D. Hafstad, J. Lund, L. Rossvoll, E. Aasum. Exercise of obese mice induces cardioprotection and oxygen sparing in hearts exposed to high-fat load. American Journal of Physiology-Heart and Circulatory Physiology, 313 (2017) H1054-H1062.


    Forskningsinteresser

    I have 16 years of experience within the basal research in cardiac metabolism/energetics, and diabetes/obesity, using the isolated working heart set up with a repertoire of experimental biochemical techniques. My area of expertise is measurements of myocardial substrate uptake and oxidation rates as well as assessment of cardiac function and mechanoenergetics in isolated working mouse hearts. In my Post-Doc I was studying cardiac adaptations following intensity controlled treadmill running of rodents with a focus on exercise-induced effects on cardiac function, metabolism and mechanoenergetics in lean and obese models. Lately my focus has been on the ROS producing enzymes: NADPH oxidases and their role redox signalling in the heart. I have been studing their roles in cardiac metabolism, hypertrophic responses, exercise adaptation, in the development of diabetic ventricular and energetic dysfunction and cardiac metabolism. Lately I have gained an interest for cardiotoxicity induced by anticancer therapies and have received funding to investigate the cardiometabolic response to anticancer therapies in cell lines and an animal model.