Bilde av Rekvig, Ole Petter
Foto: Bjørn-Kåre Iversen
Bilde av Rekvig, Ole Petter
Molekylær inflammasjon forskningsgruppe (MIRG) ole.p.rekvig@uit.no +4777646203 Tromsø MH øst L9.207

Ole Petter Rekvig


Professor emeritus


  • Ole Petter Rekvig :
    SLE classification criteria: Is “The causality principle” integrated and operative – and do the molecular and genetical network, on which criteria depend on, support the definition of SLE as “a one disease entity” – A theoretical discussion
    Autoimmunity Reviews 2023 ARKIV / DOI
  • Ole Petter Rekvig :
    SLE classification criteria: Science-based icons or algorithmic distractions – an intellectually demanding dilemma
    Frontiers in Immunology 2022 ARKIV / DOI
  • Ole Petter Rekvig :
    The Anti-DNA Antibodies: Their Specificities for Unique DNA Structures and Their Unresolved Clinical Impact—A System Criticism and a Hypothesis
    Frontiers in Immunology 2021 ARKIV / DOI
  • Ole Petter Rekvig :
    Autoimmunity and SLE: Factual and Semantic Evidence-Based Critical Analyses of Definitions, Etiology, and Pathogenesis
    Frontiers in Immunology 2020 ARKIV / DOI
  • Ole Petter Rekvig :
    The dsDNA, Anti-dsDNA Antibody, and Lupus Nephritis: What We Agree on, What Must Be Done, and What the Best Strategy Forward Could Be
    Frontiers in Immunology 2019 ARKIV / DOI
  • Unni Igesund, Grete Overvåg, Guri Rasmussen, Ole Petter Rekvig :
    Kartlegging av prosedyrer for oppdekking av instrumentbord ved kirurgiske inngrep
    Sykepleien Forskning 2019 ARKIV / DOI
  • Hege Lynum Pedersen, Kjersti Daae Horvei, Dhivya Thiyagarajan, Gudrun Norby, Natalya Seredkina, Gabriella Moroni m.fl.:
    Lupus nephritis: low urinary DNase I levels reflect loss of renal DNase I and may be utilized as a biomarker of disease progression
    The journal of pathology. Clinical research 2018 ARKIV / DOI
  • Ole Petter Rekvig :
    Systemic lupus erythematosus: Definitions, contexts, conflicts, enigmas
    Frontiers in Immunology 2018 ARKIV / DOI
  • Dhivya Thiyagarajan, Hege Lynum Pedersen, Natalya Seredkina, Kjersti Daae Horvei, Lorena Arranz, Ramon Sonneveld m.fl.:
    IL-1β Promotes a New Function of DNase I as a Transcription Factor for the Fas Receptor Gene
    Frontiers in Cell and Developmental Biology 2018 ARKIV / DOI
  • Ronald Van Vollenhoven, Alexandre Voskuyl, George Bertsias, Cynthia Aranow, Martin Aringer, Laurent Arnaud m.fl.:
    A framework for remission in SLE: Consensus findings from a large international task force on definitions of remission in SLE (DORIS)
    Annals of the Rheumatic Diseases 2017 DOI
  • Kjersti Daae Horvei, Hege Lynum Pedersen, Silje Fismen, Dhivya Thiyagarajan, Andrea Schneider, Ole Petter Rekvig m.fl.:
    Lupus nephritis progression in FcγRIIB-/-yaa mice is associated with early development of glomerular electron dense deposits and loss of renal DNase I in severe disease.
    PLOS ONE 2017 ARKIV / DOI
  • Nishant Dwivedi, Annica Hedberg, Ying Yi Zheng, Indira Neeli, Minoru Satoh, Laurence Morel m.fl.:
    B Cell Tolerance to Deiminated Histones in BALB/c, C57BL/6, and Autoimmune-Prone Mouse Strains
    Frontiers in Immunology 2017 ARKIV / DOI
  • Harri Itkonen, Michael Brown, Alfonso Urbanucci, Gregory Tredwell, Chung Ho Lau, Stefan Jörg Barfeld m.fl.:
    Lipid degradation promotes prostate cancer cell survival
    OncoTarget 2017 DOI
  • Ole Petter Rekvig, Dhivya Thiyagarajan, Hege Lynum Pedersen, Kjersti Daae Horvei, Natalya Seredkina :
    Future perspectives on pathogenesis of Lupus Nephritis: facts, problems, and potential causal therapy modalities
    American Journal of Pathology 2016 DOI
  • Christoffer Tandrup Nielsen, Ole Østergaard, Ole Petter Rekvig, Gunnar Sturfelt, Saren Jacobsen, Niels Henrik Helweg Heegaard :
    Galectin-3 binding protein links circulating microparticles with electron dense glomerular deposits in lupus nephritis
    Lupus 2015 DOI
  • Dhivya Thiyagarajan, Ole Petter Rekvig, Natalya Seredkina :
    TNFα amplifies DNaseI expression in renal tubular cells while IL-1β promotes nuclear DNaseI translocation in an endonuclease-inactive form
    PLOS ONE 2015 ARKIV / DOI
  • Ole Petter Rekvig :
    The anti-DNA antibody: Origin and impact, dogmas and controversies
    Nature Reviews Rheumatology 2015 DOI
  • Ole Petter Rekvig :
    Anti-dsDNA antibodies as a classification criterion and a diagnostic marker for systemic lupus erythematosus: Critical remarks
    Clinical and Experimental Immunology 2015 DOI
  • Hege Lynum Pedersen, Kjersti Daae Horvei, Dhivya Thiyagarajan, Natalya Seredkina, Ole Petter Rekvig :
    Murine and human lupus nephritis: pathogenic mechanisms and theoretical strategies for therapy
    Seminars in Nephrology 2015 DOI
  • Ole Petter Rekvig, Johan van der Vlag, Natalya Seredkina :
    Review: Antinucleosome antibodies: A critical reflection on their specificities and diagnostic impact
    Arthritis and Rheumatism 2014 DOI
  • Michele Compagno, Ole Petter Rekvig, Anders Bengtsson, Gunnar Sturfeld, Niels H. H. Heegaard, Andreas Jönsen m.fl.:
    Clinical phenotype associations with various types of anti-dsDNA antibodies in patients with recent onset of rheumatic symptoms. Results from a multicentre observational study
    Lupus Science and Medicine 2014 ARKIV / DOI
  • Michele Compagno, S. Jacobsen, Ole Petter Rekvig, L. Truedsson, Niels H. H. Heegaard, Johannes C Nossent m.fl.:
    Low diagnostic and predictive value of anti-dsDNA antibodies in unselected patients with recent onset of rheumatic symptoms: results from a long-term follow-up Scandinavian multicentre study
    Scandinavian Journal of Rheumatology 2013 DOI
  • Natalya Seredkina, Johan van der Vlag, Jo Berden, Elin Synnøve Mortensen, Ole Petter Rekvig :
    Lupus Nephritis: Enigmas, Conflicting Models and an Emerging Concept
    Molecular medicine (Cambridge, Mass. Print) 2013 ARKIV / DOI
  • Silje Fismen, Dhivya Thiyagarajan, Natalya Seredkina, Henrik Nielsen, Søren Jacobsen, Thomas Elung-Jensen m.fl.:
    Impact of the Tumor Necrosis Factor Receptor-Associated Protein 1 (Trap1) on Renal DNaseI Shutdown and on Progression of Murine and Human Lupus Nephritis
    American Journal of Pathology 2013 DOI
  • Annica Hedberg, Premasany Kanapathippillai, Ole Petter Rekvig, Kristin Andreassen Fenton :
    LMW Heparin Prevents Increased Kidney Expression of Proinflammatory Mediators in (NZBxNZW)F1 Mice
    Clinical & Developmental Immunology 2013 ARKIV / DOI
  • Ole Petter Rekvig, Chaim Putterman, Cinzia Casu, Hua-Xin Gao, Anna Ghirardello, Elin Synnøve Mortensen m.fl.:
    Autoantibodies in lupus: Culprits or passive bystanders?
    Autoimmunity Reviews 2012 DOI
  • Dhivya Thiyagarajan, Silje Fismen, Natalya Seredkina, Søren Jacobsen, Thomas Elung-Jensen, Anne-Lise Kamper m.fl.:
    Silencing of Renal DNaseI in Murine Lupus Nephritis Imposes Exposure of Large Chromatin Fragments and Activation of Toll Like Receptors and the Clec4e
    PLOS ONE 2012 ARKIV / DOI
  • Franz Gruber, Tuija Lundan, Rasmus Goll, Aleksandra Silye, Ingvild Mikkola, Ole Petter Rekvig m.fl.:
    BCR-ABL isoforms associated with intrinsic or acquired resistance to imatinib: more heterogeneous than just ABL kinase domain point mutations?
    Medical Oncology (MO) 2012 DOI
  • Ole Petter Rekvig, Elin Synnøve Mortensen :
    Immunity and autoimmunity to dsDNA and chromatin - the role of immunogenic DNA-binding proteins and nuclease deficiencies
    Autoimmunity 2012 DOI
  • Marko Radic, Martin Herrmann, Johan van der Vlag, Ole Petter Rekvig :
    Regulatory and pathogenetic mechanisms of autoantibodies in SLE
    Autoimmunity 2011 DOI
  • Janne erikke Mjelle, Ole Petter Rekvig, Johan van der Vlag, Kristin Andreassen Fenton :
    Nephritogenic antibodies bind in glomeruli through interaction with exposed chromatin fragments and not with renal cross-reactive antigens
    Autoimmunity 2011 DOI
  • Annica Hedberg, Elin Mortensen, Ole Petter Rekvig :
    Chromatin as a target antigen in human and murine lupus nephritis
    Arthritis Research & Therapy 2011 DOI
  • Annica Hedberg, Silje Fismen, Kristin Andreassen Fenton, Christopher Graham Fenton, Bjarne Østerud, Elin Mortensen m.fl.:
    Heparin Exerts a Dual Effect on Murine Lupus Nephritis by Enhancing Enzymatic Chromatin Degradation and Preventing Chromatin Binding in Glomerular Membranes
    Arthritis and Rheumatism 2011 DOI
  • Mariann Hellvik Jørgensen, Ole Petter Rekvig, Rasmus S. Jacobsen, Søren Jacobsen, Kristin Andreassen Fenton :
    Circulating levels of chromatin fragments are inversely correlated with anti-dsDNA antibody levels in human and murine systemic lupus erythematosus
    Immunology Letters 2011 DOI
  • Natalya Seredkina, Ole Petter Rekvig :
    Acquired loss of renal nuclease activity is restricted to DNaseI and is an organ-selective feature of murine lupus nephritis
    American Journal of Pathology 2011 DOI
  • Anders Aune Tveita, Ole Petter Rekvig :
    Alterations in Wnt Pathway Activity in Mouse Serum and Kidneys During Lupus Development
    Arthritis and Rheumatism 2011 DOI
  • Silje Fismen, Elin Mortensen, Ole Petter Rekvig :
    Nuclease deficiencies promote end-stage lupus nephritis but not nephritogenic autoimmunity in (NZBxNZW) F1 mice
    Immunology and Cell Biology 2011 DOI
  • Kristin Andreassen Fenton, berit TØmmerÅs, Tony Norman Marion, Ole Petter Rekvik :
    Pure anti-dsDNA mAbs need chromatin structures to promote glomerular mesangial deposits in BALB/c mice
    Autoimmunity 2010 DOI
  • Silje Fismen, Elin Mortensen, Ole Petter Rekvig :
    Nuclease deficiencies promote end-stage lupus nephritis but not nephritogenic autoimmunity in (NZB x NZW) F1 mice
    Immunology and Cell Biology 2010 DOI
  • M Mosca, C Tani, M Aringer, S Bombardieri, D Boumpas, R Brey m.fl.:
    European League Against Rheumatism recommendations for monitoring patients with systemic lupus erythematosus in clinical practice and in observational studies
    Annals of the Rheumatic Diseases 2010 DOI
  • Annica Hedberg, Silje Fismen, Kristin Andreassen Fenton, Elin Mortensen, Ole Petter Rekvig :
    Deposition of chromatin-IgG complexes in skin of nephritic MRL-lpr/lpr mice is associated with increased local matrix metalloprotease activities
    Experimental Dermatology 2010 DOI
  • Svetlana Zykova, Anders Tveita, Ole Petter Rekvik :
    Renal Dnase1 Enzyme Activity and Protein Expression Is Selectively Shut Down in Murine and Human Membranoproliferative Lupus Nephritis
    PLOS ONE 2010 ARKIV / DOI
  • Silje Fismen, Annica Hedberg, Kristin Andreassen Fenton, S Jacobsen, E Krarup, AL Kamper m.fl.:
    Circulating chromatin-anti-chromatin antibody complexes bind with high affinity to dermo-epidermal structures in murine and human lupus nephritis
    Lupus 2009 DOI
  • Janne erikke Mjelle, manar Kalaaji, Ole Petter Rekvik :
    Exposure of chromatin and not high affinity for dsDNA determines the nephritogenic impact of anti-dsDNA antibodies in (NZBNZW)F1 mice
    Autoimmunity 2009 DOI
  • M Mosca, C Tani, M Aringer, S Bombardieri, D Boumpas, R Brey m.fl.:
    EULAR Recommendations for monitoring systemic lupus erythematosus patients in clinical practice and in observational studied
    Annals of the Rheumatic Diseases 2009 DOI
  • Hege Lynum Pedersen, Kjersti Daae Horvei, Dhivya Thiyagarajan, Gudrun Norby, Natalya Seredkina, Gabriella Moroni m.fl.:
    LUPUS NEPHRITIS: SEVERELY REDUCED URINARY DNASE I LEVELS REFLECT LOSS OF RENAL DNASE I, DISEASE PROGRESSION AND MAY REDUCE THE NEED FOR RENAL BIOPSIES
    2018
  • Ole Petter Rekvig, Johan van der Vlag :
    The pathogenesis and diagnosis of systemic lupus erythematosus: Still not resolved
    Seminars in Immunopathology 2014 DOI
  • michele compagno, Søren Jacobsen, Ole Petter Rekvig, Lennart Truedsson, Niels H. H. Heegaard, Johannes C Nossent m.fl.:
    Diagnostic Accuracy of Anti-dsDNA Antibodies in Unselected Patients with Recent Onset of Rheumatic Symptoms
    Arthritis and Rheumatism 2012
  • Steinar Daae Johansen, morten Andreassen, Igor Babiak, Teshome Bizuayehu, Dag-Hugo Coucheron, M. Raafat El-Gewely m.fl.:
    Investigating miRNAs and transcriptomes at our local SOLiD sequencing facility
    2011
  • Natalya Seredkina, Ole Petter Rekvig :
    Acquired loss of renal Dnase1 is an organ specific feature for severe lupus nephritis
    2010

  • De 50 siste resultatene fra Cristin vises på siden. Se alle arbeider i Cristin her →


    Forskningsinteresser

    Informasjon på engelsk.



    MH øst L9.207


    Klikk for større kart