Sylte, Ingebrigt

Professor, forskningsgruppeleder, Molekylær farmakologi og toksikologi

77644705

ingebrigt.sylte@uit.no

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Tromsø

MH L9.121 (Klikk for større kartbeskrivelse)

Reseptorer og transportproteiner i CNS som mål for legemidler

Molekylære mekanismer og inhibering av bakterielle og humane zink proteaser

Farmakologi

Vitenskapelige artikler og bokkapitler
Andre

Rahman, Fatema; Nguyen, Tra-Mi; Adekoya, Olayiwola; Campestre, Cristina; Tortorella, Paolo; Sylte, Ingebrigt; Winberg, Jan-Olof. Inhibition of bacterial and human zincmetalloproteases by bisphosphonate- and catechol-containing compounds. Journal of Enzyme Inhibition and Medicinal Chemistry 2021; Volum 36 (1). ISSN 1475-6366.s 819 - 830.s doi: 10.1080/14756366.2021.1901088.

Mortensen, Åse-Karen; Mæhre, Silje; Kristiansen, kurt; Heimstad, Eldbjørg Sofie; Gabrielsen, Geir W.; Jenssen, Bjørn Munro; Sylte, Ingebrigt. Homology modeling to screen for potential binding of contaminants to thyroid hormone receptor and transthyretin in glaucous gull (Larus hyperboreus) and herring gull (Larus argentatus). Computational Toxicology 2020; Volum 13:100120. ISSN 2468-1113.s 1 - 8.s doi: 10.1016/j.comtox.2020.100120.

Ezawa, Takuya; Saito, Ryosuke; Suzuki, Shusuke; Sugiyama, Satoshi; Sylte, Ingebrigt; Kurita, Noriyuki. Protonation states of central amino acids in a zinc metalloprotease complexed with inhibitor: Molecular mechanics optimizations and ab initio molecular orbital calculations. Biophysical Chemistry 2020. ISSN 0301-4622.s doi: 10.1016/j.bpc.2020.106368.

Dawadi, Rangita; Malla, Nabin; Hegge, Beate; Wushur, Imin; Berg, Eli; Svineng, Gunbjørg; Sylte, Ingebrigt; Winberg, Jan-Olof. Molecular Interactions Stabilizing the Promatrix Metalloprotease-9·Serglycin Heteromer. International Journal of Molecular Sciences 2020; Volum 21 (12). ISSN 1422-0067.s 4205 - .s doi: 10.3390/ijms21124205.

Evenseth, Linn; Ocello, Riccardo; Gabrielsen, Mari; Masetti, Matteo; Recanatini, Maurizio; Sylte, Ingebrigt; Cavalli, Andrea. Exploring Conformational Dynamics of the Extracellular Venus flytrap Domain of the GABA B Receptor: A Path-Metadynamics Study. Journal of Chemical Information and Modeling 2020; Volum 60 (4). ISSN 1549-9596.s 2294 - 2303.s doi: 10.1021/acs.jcim.0c00163.

Evenseth, Linn; Gabrielsen, Mari; Sylte, Ingebrigt. The GABAB Receptor—Structure, Ligand Binding and Drug Development. Molecules 2020; Volum 25 (13). ISSN 1420-3049.s 1 - 19.s doi: 10.3390/molecules25133093.

Fjelldal, Marthe Fredheim; Freyd, Thibaud; Evenseth, Linn; Sylte, Ingebrigt; Ring, Avi; Paulsen, Ragnhild Elisabeth. Exploring the overlapping binding sites of ifenprodil and EVT‐101 in GluN2B‐containing NMDA receptors using novel chicken embryo forebrain cultures and molecular modeling. Pharmacology Research & Perspectives 2019; Volum 7 (3). ISSN 2052-1707.s 1 - 15.s doi: 10.1002/prp2.480.

Ezawa, Takuya; Sugiyama, Satoshi; Ara, Ayami; Sylte, Ingebrigt; Kurita, Noriyuki. Design of galardine analogs as putative psudolysin inhibitors based on ab initio fragment molecular orbital calculations. Journal of Biomolecular Structure and Dynamics 2019. ISSN 0739-1102.s doi: 10.1080/07391102.2019.1656672.

Arnesen, Liv Henriette; Haj Yasein, Nadia; Tungen, Jørn Eivind; Södling, Helen; Matthews, Jason; Paulsen, Steinar M; Nebb, Hilde Irene; Sylte, Ingebrigt; Hansen, Trond Vidar; Sæther, Thomas. Molecular modelling, synthesis, and biological evaluations of a 3,5-disubstituted isoxazole fatty acid analogue as a PPARα-selective agonist. (Fulltekst: https://doi.org/10.1016/j.bmc.2019.07.032 Bioorganic & Medicinal Chemistry 2019; Volum 27 (18). ISSN 0968-0896.s 4059 - 4068.s doi: 10.1016/j.bmc.2019.07.032.

Evenseth, Linn; Warszycki, Dawid; Bojarski, Andrzej J; Gabrielsen, Mari; Sylte, Ingebrigt. In Silico Methods for the Discovery of Orthosteric GABAB Receptor Compounds. Molecules 2019; Volum 24 (5). ISSN 1420-3049.s 1 - 20.s doi: 10.3390/molecules24050935.

Evenseth, Linn M; Kristiansen, Kurt; Song, You; Tollefsen, Knut Erik; Sylte, Ingebrigt. In silico site-directed mutagenesis of the Daphnia magna ecdysone receptor identifies critical amino acids for species-specific and inter-species differences in agonist binding. Computational Toxicology 2019; Volum 12. ISSN 2468-1113.s doi: 10.1016/j.comtox.2019.100091.

Al-Kazaale, Nora; Tran, Phuong Dan Dinh; Haidari, Farhad; Solum, Eirik Johansson; Liekens, Sandra; Vervaeke, Peter; Sylte, Ingebrigt; Cheng, Jing-Jy; Vik, Anders; Hansen, Trond Vidar. Synthesis, molecular modeling and biological evaluation of potent analogs of 2-methoxyestradiol. Steroids 2018; Volum 136. ISSN 0039-128X.s 47 - 55.s doi: 10.1016/j.steroids.2018.05.002.

Doering, Jon A.; Lee, Sehan; Kristiansen, kurt; Evenseth, Linn; Sylte, Ingebrigt; Barron, Mace G.; Lalone, Carlie. In silico site-directed mutagenesis informs species-specific predictions of chemical susceptibility derived from the Sequence Alignment to Predict Across Species Susceptibility (SeqAPASS) tool. Toxicological Sciences 2018; Volum 166 (1). ISSN 1096-6080.s 131 - 145.s doi: 10.1093/toxsci/kfy186.

Sylte, Ingebrigt; Dawadi, Rangita; Malla, Nabin; von Hofsten, Susannah; Nguyen, Tra-Mi; Solli, Ann Iren; Berg, Eli; Adekoya, Olayiwola; Svineng, Gunbjørg; Winberg, Jan-Olof. The selectivity of galardin and an azasugar-based hydroxamate compound for human Matrix metalloproteases and bacterial metalloproteases. PLOS ONE 2018; Volum 13 (8). ISSN 1932-6203.s doi: 10.1371/journal.pone.0200237.

Hill, Katie L.; Mortensen, Åse-Karen; Teclechiel, Daniel; Willmore, William G.; Sylte, Ingebrigt; Jenssen, Bjørn Munro; Letcher, Robert James. In Vitro and in Silico Competitive Binding of Brominated Polyphenyl Ether Contaminants with Human and Gull Thyroid Hormone Transport Proteins. Environmental Science and Technology 2018; Volum 52 (3). ISSN 0013-936X.s 1533 - 1541.s doi: 10.1021/acs.est.7b04617.

Åstrand, Ove Alexander Høgmoen; Viktorsson, Elvar Örn; Kristensen, Aleksander Lim; Ekeberg, Dag; Røberg-Larsen, Hanne; Wilson, Steven Ray Haakon; Gabrielsen, Mari; Sylte, Ingebrigt; Rustan, Arild; Thoresen, G. Hege; Rongved, Pål; Kase, Eili Tranheim. Synthesis, in vitro and in vivo biological evaluation of new oxysterols as modulators of the liver X receptors. Journal of Steroid Biochemistry and Molecular Biology 2017; Volum 165. ISSN 0960-0760.s 323 - 330.s doi: 10.1016/j.jsbmb.2016.07.010.

Ara, Ayami; Kadoya, Ryushi; Ishimura, Hiromi; Shimamura, Kanako; Sylte, Ingebrigt; Kurita, Noriyuki. Specific interactions between zinc metalloproteinase and its inhibitors: Ab initio fragment molecular orbital calculations. Journal of Molecular Graphics and Modelling 2017; Volum 75. ISSN 1093-3263.s 277 - 286.s doi: 10.1016/j.jmgm.2017.05.013.

Freyd, Thibaud; Warszycki, Dawid; Mordalski, Stefan; Bojarski, Andrzej J; Sylte, Ingebrigt; Gabrielsen, Mari. Ligand-guided homology modelling of the GABAB2 subunit of the GABAB receptor. PLOS ONE 2017; Volum 12 (3). ISSN 1932-6203.s doi: 10.1371/journal.pone.0173889.

Warszycki, Dawid; Rueda, Manuel; Mordalski, Stefan; Kristiansen, kurt; Satala, Grzegorz; Rataj, Krzysztof; Chilmonczyk, Zdzislaw; Sylte, Ingebrigt; Abagyan, Ruben; Bojarski, Andrzej J. From Homology Models to a Set of Predictive Binding Pockets-a 5-HT1A Receptor Case Study. Journal of Chemical Information and Computer Sciences 2017; Volum 57 (2). ISSN 0095-2338.s 311 - 321.s doi: 10.1021/acs.jcim.6b00263.

Chilmonczyk, Zdzislaw; Bojarski, Andrzej J.; Pilc, Andrzej; Sylte, Ingebrigt. Serotonin transporter and receptor ligands with antidepressant activity as neuroprotective and proapoptotic agents. Pharmacological Reports 2017; Volum 69 (3). ISSN 1734-1140.s 469 - 478.s doi: 10.1016/j.pharep.2017.01.011.

Viktorsson, Elvar Örn; Gabrielsen, Mari; Kumarachandran, Nugalya; Sylte, Ingebrigt; Rongved, Pål; Åstrand, Ove Alexander Høgmoen; Kase, Eili Tranheim. Regulation of liver X receptor target genes by 22-functionalized oxysterols. Synthesis, in silico and in vitro evaluations. Steroids 2017; Volum 118. ISSN 0039-128X.s 119 - 127.s doi: 10.1016/j.steroids.2016.12.003.

Routti, Heli Anna Irmeli; Lille-Langøy, Roger; Berg, Mari Katrine; Fink, Trine; Harju, Mikael; Kristiansen, Kurt; Rostkowski, Pawel Marian; Rusten, Marte; Sylte, Ingebrigt; Øygarden, Lene Eidsvik; Goksøyr, Anders. Environmental chemicals modulate polar bear (Ursus maritimus) Peroxisome Proliferator-Activated Receptor Gamma (PPARG) and adipogenesis in vitro. Environmental Science and Technology 2016; Volum 50 (19). ISSN 0013-936X.s 10708 - 10720.s doi: 10.1021/acs.est.6b03020.

Sjøli, Stian; Nuti, Elisa; Camodeca, Caterina; Bilto, Irina; Rossello, Armando; Winberg, Jan-Olof; Sylte, Ingebrigt; Adekoya, Olayiwola. Synthesis, experimental evaluation and molecular modelling of hydroxamate derivatives as zinc metalloproteinase inhibitors. European Journal of Medicinal Chemistry 2016; Volum 108. ISSN 0223-5234.s 141 - 153.s doi: 10.1016/j.ejmech.2015.11.019.

Kaupang, Åsmund; Paulsen, Steinar Martin; Steindal, Calin Constantin; Ravna, Aina Westrheim; Sylte, Ingebrigt; Halvorsen, Trine Grønhaug; Thoresen, G. Hege; Hansen, Trond Vidar. Synthesis, biological evaluation and molecular modeling studies of the PPARβ/δ antagonist CC618. European Journal of Medicinal Chemistry 2015; Volum 94. ISSN 0223-5234.s 229 - 236.s doi: 10.1016/j.ejmech.2015.03.006.

Wushur, Imin; Sylte, Ingebrigt; Winberg, Jan-Olof. The catalytic reaction mechanism of drosophilid alcohol dehydrogenases. Perspectives in Science 2015; Volum 4. ISSN 2213-0209.s 46 - 56.s doi: 10.1016/j.pisc.2014.12.008.

Odunuga, Odutayo O.; Adekoya, Olayiwola; Sylte, Ingebrigt. High-level expression of pseudolysin, the extracellular elastase of Pseudomonas aeruginosa, in Escherichia coli and its purification. Protein Expression and Purification 2015; Volum 113. ISSN 1046-5928.s 79 - 84.s doi: 10.1016/j.pep.2015.05.005.

Chilmonczyk, Zdzislaw; Bojarski, Andrzej Jacek; Pilc, Andrzej; Sylte, Ingebrigt. Functional selectivity and antidepressant activity of serotonin 1A receptor ligands. International Journal of Molecular Sciences 2015; Volum 16 (8). ISSN 1422-0067.s 18474 - 18506.s doi: 10.3390/ijms160818474.

Solum, Eirik Johansson; Cheng, Jing-Jy; Sylte, Ingebrigt; Vik, Anders; Hansen, Trond Vidar. Synthesis, biological evaluation and molecular modeling of new analogs of the anti-cancer agent 2-methoxyestradiol: potent inhibitors of angiogenesis. RSC Advances 2015; Volum 5 (41). ISSN 2046-2069.s 32497 - 32504.s doi: 10.1039/c5ra03570h.

Åstrand, Ove Alexander Høgmoen; Sandberg, Marcel; Sylte, Ingebrigt; Gorbitz, Carl Henrik; Thoresen, G. Hege; Kase, Eili Tranheim; Rongved, Pål. Synthesis and initial biological evaluation of new mimics of the LXR-modulator 22(S)-hydroxycholesterol. Bioorganic & Medicinal Chemistry 2014; Volum 22 (1). ISSN 0968-0896.s 643 - 650.s doi: 10.1016/j.bmc.2013.10.024.

Kufareva, Irina; Katritch, Vsevolod; Freyd, Thibaud; Gabrielsen, Mari; Kristiansen, kurt; Sylte, Ingebrigt; Stevens, Raymond C.; Abagyan, Ruben. Advances in GPCR modeling evaluated by the GPCR Dock 2013 assessment: Meeting new challenges. Structure 2014; Volum 22 (8). ISSN 0969-2126.s 1120 - 1139.s doi: 10.1016/j.str.2014.06.012.

Jantan, Ibrahim; Bukhari, Syed Nasir Abbas; Adekoya, Olayiwola; Sylte, Ingebrigt. Studies of synthetic chalcone derivatives as potential inhibitors of secretory phospholipase A2, cyclooxygenases, lipoxygenase and pro-inflammatory cytokines. Drug Design, Development and Therapy 2014; Volum 8. ISSN 1177-8881.s 1405 - 1418.s doi: 10.2147/DDDT.S67370.

Adekoya, Olayiwola; Sjøli, Stian; Wushur, Imin; Bilto, Irina; Marques, Sergio M; Santos, M Amelia; Nuti, Elisa; Cercignani, Giovanni; Rossello, Armando; Winberg, Jan-Olof; Sylte, Ingebrigt. Inhibition of pseudolysin and thermolysin by hydroxamate-based MMP inhibitors. European Journal of Medicinal Chemistry 2014; Volum 89. ISSN 0223-5234.s 340 - 348.s doi: 10.1016/j.ejmech.2014.10.009.

Chilmonczyk, Zdzislaw; Bojarski, Andrzej J.; Sylte, Ingebrigt. Ligand-directed traffickingof receptor stimulus. Pharmacological Reports 2014; Volum 66 (6). ISSN 1734-1140.s 1011 - 1021.s doi: 10.1016/j.pharep.2014.06.006.

Wushur, Imin; Winberg, Jan-Olof; Sylte, Ingebrigt. Comparative molecular dynamic simulations of wild type and Thr114Val mutated Scaptodrosophila lebanonensis alcohol dehydrogenase. Journal of Biomolecular Structure and Dynamics 2014; Volum 32 (3). ISSN 0739-1102.s 465 - 476.s doi: 10.1080/07391102.2013.776502.

Gabrielsen, Mari; Kurczab, Rafal; Siwek, Agata; Wolak, Malgorzata; Ravna, Aina Westrheim; Kristiansen, kurt; Kufareva, Irina; Abagyan, Ruben; Nowak, Gabriel; Chilmonczyk, Zdzislaw; Sylte, Ingebrigt; Bojarski, Andrzej J.. Identification of novel serotonin transporter compounds by virtual Screening. Journal of Chemical Information and Modeling 2014; Volum 54 (3). ISSN 1549-9596.s 933 - 943.s doi: 10.1021/ci400742s.

Sjøli, Stian; Solli, Ann Iren; Akselsen, Øyvind Wilhelm; Jiang, Yang; Berg, Eli; Hansen, Trond Vidar; Sylte, Ingebrigt; Winberg, Jan-Olof. PAC-1 and isatin derivatives are weak matrix metalloproteinase inhibitors. Biochimica et Biophysica Acta 2014; Volum 10 (1840). ISSN 0006-3002.s 3162 - 3169.s doi: 10.1016/j.bbagen.2014.07.011.

Åstrand, Ove Alexander Høgmoen; Gikling, Ingveig; Sylte, Ingebrigt; Rustan, Arild; Thoresen, G. Hege; Rongved, Pål; Kase, Eili Tranheim. Development of new LXR modulators that regulate LXR target genes and reduce lipogenesis in human cell models. European Journal of Medicinal Chemistry 2014; Volum 74. ISSN 0223-5234.s 258 - 263.s doi: 10.1016/j.ejmech.2014.01.003.

Lindin, inger; Wuxiuer, Yimingjiang; Ravna, Aina Westrheim; Moens, Ugo; Sylte, Ingebrigt. Comparative molecular dynamics simulations of mitogen-activated protein kinase-activated protein kinase 5. International Journal of Molecular Sciences 2014; Volum 15 (3). ISSN 1422-0067.s 4878 - 4902.s doi: 10.3390/ijms15034878.

Baglo, Yan; Gabrielsen, Mari; Sylte, Ingebrigt; Gederaas, Odrun Arna. Homology Modeling of Human <gamma>-Butyric Acid Transporters and the Binding of Pro-drugs 5-Aminolevulinic Acid and Methyl Aminolevulinic Acid used in Photodynamic Therapy. PLOS ONE 2013; Volum 8 (6). ISSN 1932-6203.s doi: 10.1371/journal.pone.0065200.

Sylte, Ingebrigt; Adekoya, Olayiwola. Thermolsyin. Springer 2013 ISBN 978-1-4614-1532-9.s 2213 - 2221.s doi: 10.1007/978-1-4614-1533-6.

Warszycki, Dawid; Mordalski, Stefan; Kristiansen, kurt; Kafel, Rafal; Sylte, Ingebrigt; Chilmonczyk, Zdzislaw; Bojarski, Andrzej J.. A Linear Combination of Pharmacophore Hypotheses as a New Tool in Search of New Active Compounds - An Application for 5-HT1A Receptor Ligands. PLOS ONE 2013; Volum 8 (12). ISSN 1932-6203.s doi: 10.1371/journal.pone.0084510.

Larsen, Anett Kristin; Kristiansen, kurt; Sylte, Ingebrigt; Seternes, Ole Morten; Bang, Berit. Differences in PAR-2 activating potential by king crab (Paralithodes camtschaticus), salmon (Salmo salar), and bovine (Bos taurus) trypsin. BMC Research Notes 2013; Volum 6. ISSN 1756-0500.s 281 - .s doi: 10.1186/1756-0500-6-281.

Wuxiuer, Yimingjiang; Winberg, Jan-Olof; Sylte, Ingebrigt. Comparative molecular dynamics simulations of wild type and Thr114Val mutated Scaptodrosophila lebanonensis alcohol dehydrogenase. Journal of Biomolecular Structure and Dynamics 2013; Volum 32 (3). ISSN 0739-1102.s 465 - 476.s doi: 10.1080/07391102.2013.776502.

Lindin, inger; Wuxiuer, Yimingjiang; Kufareva, Irina; Abagyan, Ruben; Moens, Ugo; Sylte, Ingebrigt; Ravna, Aina Westrheim. Homology modeling and ligand docking of Mitogen-activated protein kinase-activated protein kinase 5 (MK5). Theoretical Biology Medical Modelling 2013; Volum 10. ISSN 1742-4682.s doi: 10.1186/1742-4682-10-56.

Gabrielsen, Mari; Wolosewicz, Karol; Zawadzka, Anna; Kossakowski, Jerzy; Nowak, Gabriel; Wolak, Malgorzata; Stachowicz, Katarzyna; Siwek, Agata; Ravna, Aina Westrheim; Kufareva, Irina; Kozerski, Lech; Bednarek, Elzbieta; Sitkowski, Jerzy; Bocian, Wojciech; Abagyan, Ruben; Bojarski, Andrezej J; Sylte, Ingebrigt; Chilmonczyk, Zdzislaw. Synthesis, Antidepressant Evaluation and Docking Studies of Long-Chain Alkylnitroquipazines as Serotonin Transporter Inhibitors. Chemical Biology and Drug Design (CB&DD) 2013; Volum 81 (6). ISSN 1747-0277.s 695 - 706.s doi: 10.1111/cbdd.12116.

Gabrielsen, Mari; Ravna, aina westrheim; Kristiansen, kurt; Sylte, Ingebrigt. Substrate binding and translocation of the serotonin transporter studied by docking and molecular dynamics simulations. Journal of Molecular Modeling 2012; Volum 18 (3). ISSN 1610-2940.s 1073 - 1085.s doi: 10.1007/s00894-011-1133-1.

Khan, Mahmud Tareq Hassan; Dedachi, Kenichi; Matsui, Toshiro; Kurita, Noriyuki; Borgatti, Monica; Gambari, Roberto; Sylte, Ingebrigt. Dipeptide Inhibitors of Thermolysin and Angiotensin I-Converting Enzyme. Current Topics in Medicinal Chemistry 2012; Volum 12 (16). ISSN 1568-0266.s 1748 - 1762.s doi: 10.2174/1568026611209061748.

Sylte, Ingebrigt; Ravna, aina westrheim. Homology Modeling of Transporter Proteins (Carriers and Ion Channels). Humana Press 2012 (857). ISSN 1064-3745.s 281 - 299.s doi: 10.1007/978-1-61779-588-6_12.

Khan, Mahmud Tareq Hassan; Wuxiuer, Yimingjiang; Sylte, Ingebrigt. Binding Modes and Pharmacophore Modelling of Thermolysin Inhibitors. Mini-Reviews in Medicinal Chemistry 2012; Volum 12 (6). ISSN 1389-5575.s 515 - 533.

Fadnes, Bodil Irene; Hadler-Olsen, Elin Synnøve; Sylte, Ingebrigt; Uhlin-Hansen, Lars; Winberg, Jan-Olof. Matrix metalloproteinase complexes and their biological significance. Walter de Gruyter 2012 ISBN 978-3-11-025876-9.s 291 - 314.s doi: 10.1515/9783110258776.291.

Wuxiuer, Yimingjiang; Morgunova, Ekaterina; Cols, Neus; Popov, Alexander; Karshikoff, Andrey; Sylte, Ingebrigt; Gonzàlez-Duarte, Roser; Ladenstein, Rudolf; Winberg, Jan-Olof. An intact eight-membered water chain in drosophilid alcohol dehydrogenases is essential for optimal enzyme activity. The FEBS Journal 2012; Volum 279 (16). ISSN 1742-464X.s 2940 - 2956.s doi: 10.1111/j.1742-4658.2012.08675.x.

Jaronczyk, Malgorzata; Wolosewicz, Karol; Gabrielsen, Mari; Nowak, Gabriel; Kufareva, Irina; Mazurek, Aleksander P; Ravna, aina westrheim; Abagyan, Ruben; Bojarski, Andrezej J; Sylte, Ingebrigt; Chilmonczyk, Zdzislaw. Synthesis, in vitro binding studies and docking of long-chain arylpiperazine nitroquipazine analogues, as potential serotonin transporter inhibitors. European Journal of Medicinal Chemistry 2012; Volum 49. ISSN 0223-5234.s 200 - 210.s doi: 10.1016/j.ejmech.2012.01.012.

Hirakawa, Tatsuya; Fujita, Seiya; Ohyama, Tatsuya; Dedachi, Kenichi; Khan, Mahmud Tareq Hassan; Sylte, Ingebrigt; Kurita, Noriyuki. Specific interactions and binding energies between thermolysin and potent inhibitors: Molecular simulations based on ab initio molecular orbital method. Journal of Molecular Graphics and Modelling 2012; Volum 33. ISSN 1093-3263.s 1 - 11.s doi: 10.1016/j.jmgm.2011.10.006.

Witowska-Jarosz, Janina; Jaronczyk, Malgorzata; Mazurek, Aleksander P; Sylte, Ingebrigt; Bojarski, Andrezej J; Chilmonczyk, Zdzislaw; Jarosz, Maciej. Mass-spectrometric studies of new 6-nitroquipazines-serotonin transporter inhibitors. Analytical and Bioanalytical Chemistry 2012; Volum 402 (1). ISSN 1618-2642.s 537 - 541.s doi: 10.1007/s00216-011-5410-8.

Hessvik, Nina Pettersen; Bakke, Siril Skaret; Smith, Robert; Ravna, aina westrheim; Sylte, Ingebrigt; Rustan, Arild; Thoresen, G. Hege; Kase, Eili Tranheim. The liver X receptor modulator 22(S)-hydroxycholesterol exerts cell-type specific effects on lipid and glucose metabolism. Journal of Steroid Biochemistry and Molecular Biology 2012; Volum 128. ISSN 0960-0760.s 154 - 164.s doi: 10.1016/j.jsbmb.2011.10.006.

Gabrielsen, Mari; Kurczab, Rafal; Ravna, aina westrheim; Kufareva, Irina; Abagyan, Ruben; Chilmonczyk, Zdzislaw; Bojarski, Andrezej J; Sylte, Ingebrigt. Molecular mechanism of serotonin transporter inhibition elucidated by a new flexible docking protocol. European Journal of Medicinal Chemistry 2012; Volum 47. ISSN 0223-5234.s 24 - 37.s doi: 10.1016/j.ejmech.2011.09.056.

Hadler-Olsen, Elin Synnøve; Fadnes, Bodil Irene; Sylte, Ingebrigt; Uhlin-Hansen, Lars; Winberg, Jan-Olof. Regulation of matrix metalloproteinase activity in health and disease. The FEBS Journal 2011; Volum 278 (1). ISSN 1742-464X.s 28 - 45.s doi: 10.1111/j.1742-4658.2010.07920.x.

Sylte, Ingebrigt; Ravna, aina westrheim; Dahl, Svein G.. Templates and models of monoamine transporter proteins. Current Medicinal Chemistry 2011; Volum 18 (30). ISSN 0929-8673.s 4651 - 4658.

Dedachi, Kenichi; Hirakawa, Tatsuya; Fujita, Seiya; Khan, Mahmud Tareq Hassan; Sylte, Ingebrigt; Kurita, Noriyuki. Specific Interactions and Binding Free Energies Between Thermolysin and Dipeptides: Molecular Simulations Combined with Ab Initio Molecular Orbital and Classical Vibrational Analysis. Journal of Computational Chemistry 2011; Volum 32 (14). ISSN 0192-8651.s 3047 - 3057.s doi: 10.1002/jcc.21887.

Mordalski, Stefan; Kosciolek, Tomasz; Kristiansen, kurt; Sylte, Ingebrigt; Bojarski, Andrezej J. Protein binding site analysis by means of structural interaction fingerprint patterns. Bioorganic & Medicinal Chemistry Letters 2011; Volum 21 (22). ISSN 0960-894X.s 6816 - 6819.s doi: 10.1016/j.bmcl.2011.09.027.

Ciocoiu, Calin C.; Ravna, aina westrheim; Sylte, Ingebrigt; Rustan, Arild; Hansen, Trond Vidar. Synthesis, molecular modeling studies and biological evaluation of fluorine substituted analogs of GW 501516. Bioorganic & Medicinal Chemistry 2011; Volum 19. ISSN 0968-0896.s 6982 - 6988.s doi: 10.1016/j.bmc.2011.10.020.

Kostenko, Sergiy Viktorovich; Khan, Mahmud Tareq Hassan; Sylte, Ingebrigt; Moens, Ugo. The diterpenoid alkaloid noroxoaconitine is a Mapkap kinase 5 (MK5/PRAK) inhibitor. Cellular and Molecular Life Sciences (CMLS) 2011; Volum 68 (2). ISSN 1420-682X.s 289 - 301.s doi: 10.1007/s00018-010-0452-1.

Kostenko, Sergiy Viktorovich; Khan, Mahmud Tareq Hassan; Moens, Ugo; Sylte, Ingebrigt. The diterpenoid alkaloid Noroxoaconitine is a MAPKAP Kinase 5 (MK5/PRAK) inhibitor. Cellular and Molecular Life Sciences (CMLS) 2010. ISSN 1420-682X.s doi: 10.1007/s00018-010-0452-1.

Ciocoiu, Calin Constantin; Ravna, aina westrheim; Sylte, Ingebrigt; Hansen, Trond Vidar. Synthesis, Biological Evaluation and Molecular Modeling of GW 501516 Analogues. Archiv der Pharmazie 2010; Volum 343 (11-12). ISSN 0365-6233.s 612 - 624.s doi: 10.1002/ardp.201000189.

Odlo, Kristin; Fournier-Dit-Chabert, Jérémie; Ducki, Sylvie; Gani, Osman A.B.S.M.; Sylte, Ingebrigt; Hansen, Trond Vidar. 1,2,3-Triazole analogs of combretastatin A-4 as potential microtubule-binding agents. Bioorganic & Medicinal Chemistry 2010; Volum 18 (18). ISSN 0968-0896.s 6874 - 6885.s doi: 10.1016/j.bmc.2010.07.032.

Kurczab, Rafal; Nowak, Mateusz; Chilmonczyk, Zdzislaw; Sylte, Ingebrigt; Bojarski, Andrezej J. The development and validation of a novel virtual screening cascade protocol to identify potential serotonin 5-HT7R antagonists. Bioorganic & Medicinal Chemistry Letters 2010; Volum 20 (8). ISSN 0960-894X.s 2465 - 2468.s doi: 10.1016/j.bmcl.2010.03.012.

Khan, Mahmud Tareq Hassan; Khan, R.; Wuxiuer, Yimingjiang; Arfan, M.; Ahmed, M.; Sylte, Ingebrigt. Identification of novel quinazolin-4(3H)-ones as inhibitors of thermolysin, the prototype of the M4 family of proteinases. Bioorganic & Medicinal Chemistry 2010; Volum 18 (12). ISSN 0968-0896.s 4317 - 4327.s doi: 10.1016/j.bmc.2010.04.083.

Ravna, aina westrheim; Sager, Georg; Dahl, Svein G.; Sylte, Ingebrigt. Membrane transporters: Structure, function and targets for drug design. Springer Publishing Company 2009 (4) ISBN 978-3-540-87911-4. ISSN 1862-2461.s 15 - 51.

Khan, Mahmud Tareq Hassan; Fuskevaag, OM; Sylte, Ingebrigt. Discovery of Potent Thermolysin Inhibitors Using Structure Based Virtual Screening and Binding Assays. Journal of Medicinal Chemistry 2009; Volum 52 (1). ISSN 0022-2623.s 48 - 61.s doi: 10.1021/jm8008019.

Adekoya, Olayiwola; Sylte, Ingebrigt. The Thermolysin Family (M4) of Enzymes: Therapeutic and Biotechnological Potential. Chemical Biology and Drug Design (CB&DD) 2009; Volum 73 (1). ISSN 1747-0277.s 7 - 16.s doi: 10.1111/j.1747-0285.2008.00757.x.

Gani, Osman A.B.S.M.; Sylte, Ingebrigt. Molecular recognition of long chain fatty acids by peroxisome proliferator-activated receptor alpha. Medicinal Chemistry Research 2009; Volum 18 (1). ISSN 1054-2523.s 8 - 19.s doi: 10.1007/s00044-008-9102-7.

Dedachi, Kenichi; Khan, Mahmud T. H.; Sylte, Ingebrigt; Kurita, Noriyuki. A combined simulation with ab initio MO and classical vibrational analysis on the specific interactions between thermolysin and dipeptide ligands. Chemical Physics Letters 2009; Volum 479 (4-6). ISSN 0009-2614.s 290 - 295.s doi: 10.1016/j.cplett.2009.08.036.

Herold, Franciszek; Izbicki, Lukasz; Chodkowski, Andrzej; Dawidowski, Maciej; Król, Marek; Kleps, Jerzy; Turlo, Jadwiga; Wolska, Irena; Nowak, Gabriel; Stachowicz, Katarzyna; Dybala, Malgorzata; Siwek, Agata; Nowak, Mateusz; Pieniazek, Elzbieta; Jaronczyk, Malgorzata; Sylte, Ingebrigt; Mazurek, Aleksander P. Novel 4-aryl-pyrido[1,2-c]pyrimidines with dual SSRI and 5-HT1A activity: Part 2. European Journal of Medicinal Chemistry 2009; Volum 44. ISSN 0223-5234.s 4702 - 4715.s doi: 10.1016/j.ejmech.2009.07.007.

Ravna, aina westrheim; Sylte, Ingebrigt; Dahl, Svein G.. Structure and localisation of drug binding sites on neurotransmitter transporters. Journal of Molecular Modeling 2009; Volum 15 (10). ISSN 1610-2940.s 1155 - 1164.s doi: 10.1007/s00894-009-0478-1.

Khan, Mahmud T. H.; Sylte, Ingebrigt. Determinants for Psychrophilic and Thermophilic Features of Metallopeptidases of the M4 Family. In Silico Biology 2009; Volum 9. ISSN 1386-6338.s 105 - 124.s doi: 10.3233/ISB-2009-0392.

Khan, Mahmud T. H.; Sylte, Ingebrigt. Multivariate Linear Regression Models Based on ADME Descriptors and Predictions of ADMET Profile for Structurally Diverse Thermolysin Inhibitors. Letters in Drug Design & Discovery 2009; Volum 6 (6). ISSN 1570-1808.s 428 - 436.

Ravna, aina westrheim; Sylte, Ingebrigt; Sager, Georg. Binding site of ABC transporter homology models confirmed by ABCB1 crystal structure. Theoretical Biology Medical Modelling 2009; Volum 6 (20). ISSN 1742-4682.s doi: 10.1186/1742-4682-6-20.

Khan, Mahmud T. H.; Sylte, Ingebrigt. Structural Bioinformatics in the Discovery of Novel Drugs. Springer Science+Business Media B.V. 2009 ISBN 978-1-4020-6954-3.s 29 - 38.

Gani, Osman A.B.S.M.; Sylte, Ingebrigt. Molecular recognition of docosahexaenoic acid by peroxisome proliferator-activated receptors and retinoid-X receptor alpha. Journal of Molecular Graphics and Modelling 2008; Volum 27. ISSN 1093-3263.s 217 - 224.s doi: 10.1016/j.jmgm.2008.04.008.

Kvernmo, Trond; Houben, John; Sylte, Ingebrigt. Receptor-binding and pharmacokinetic properties of dopaminergic agonists. Current Topics in Medicinal Chemistry 2008; Volum 8 (12). ISSN 1568-0266.s 1049 - 1067.

Jaronczyk, Malgorzata; Chilmonczyk, Zdizlav; Mazurek, AP; Nowak, Gabriel; Ravna, aina westrheim; Kristiansen, kurt; Sylte, Ingebrigt. The molecular interactions of buspirone analogues with the serotonin transporter. Bioorganic & Medicinal Chemistry 2008; Volum 16 (20). ISSN 0968-0896.s 9283 - 9294.s doi: 10.1016/j.bmc.2008.09.005.

Ravna, aina westrheim; Sylte, Ingebrigt; Sager, Georg. A molecular model of a putative substrate releasing conformation of multidrug resistance protein 5 (MRP5). European Journal of Medicinal Chemistry 2008; Volum 43 (11). ISSN 0223-5234.s 2557 - 2567.s doi: 10.1016/j.ejmech.2008.01.015.

Dahl, Svein G.; Sylte, Ingebrigt. Molecular Structure and Dynamics of Drug Targets. Prague Medical Report 2008; Volum 109 (2-3). ISSN 1214-6994.s 107 - 112.

Gani, Osman A.B.S.M.; Adekoya, Olayiwola; Giurato, L; Spyrakis, F; Cozzini, P; Guccione, S; Winberg, Jan-Olof; Sylte, Ingebrigt. Theoretical calculations of the catalytic triad in short-chain alcohol dehydrogenases/reductases. Biophysical Journal 2008; Volum 94. ISSN 0006-3495.s doi: 10.1529/biophysj.107.111096.

Gani, Osman A.B.S.M.; Sylte, Ingebrigt. Ligand-induced stabilization and activation of peroxisome proliferator-activated receptor gamma. Chemical Biology and Drug Design (CB&DD) 2008; Volum 72. ISSN 1747-0277.s 50 - 57.s doi: 10.1111/j.1747-0285.2008.00677.x.

Odlo, K; Hentzen, J; dit Chabert, JF; Ducki, S; Gani, Osman A.B.S.M.; Sylte, Ingebrigt; Skrede, M; Flørenes, Vivi Ann; Florenes, VA; Hansen, TV. 1,5-disubstituted 1,2,3-triazoles as cis-restricted analogues of combretastatin A-4: Synthesis, molecular modeling and evaluation as cytotoxic agents and inhibitors of tubulin. Bioorganic & Medicinal Chemistry 2008; Volum 16. ISSN 0968-0896.s 4829 - 4838.s doi: 10.1016/j.bmc.2008.03.049.

Ravna, aina westrheim; Sylte, Ingebrigt; Sager, Georg. Molecular model of the outward facing state of the human P-glycoprotein (ABCB1), and comparison to a model of the human MRP5 (ABCC5). Theoretical Biology Medical Modelling 2007; Volum 4. ISSN 1742-4682.s 33 - .

Khan, Mahmud Tareq Hassan; Sylte, Ingebrigt. Predictive QSAR modeling for the sucessful predictions of the ADMET properties of candidate drug molecules. Current Drug Discovery Technologies 2007; Volum 4. ISSN 1570-1638.s 141 - 149.

Khan, Mahmud Tareq Hassan; Wuxiuer, Yimingjiang; Sylte, Ingebrigt. Molecular recognition of thermolysin and homologous zinc-metalloproteinases. Minerva biotecnologica (Testo stampato) 2007; Volum 19. ISSN 1120-4826.s 139 - 150.

Ravna, Aina Westrheim; Sylte, Ingebrigt; Kristiansen, Kurt; Dahl, Svein G.. Putative drug binding conformations of monoamine transporters. Bioorganic & Medicinal Chemistry 2006; Volum 14. ISSN 0968-0896.

Adekoya, Olayiwola; Willassen, Nils Peder; Sylte, Ingebrigt. Molecular insight into pseudolysin inhibition using the MM-PBSA and LIE methods. Journal of Structural Biology 2006; Volum 153. ISSN 1047-8477.s 129 - 144.

Adekoya, Olayiwola; Helland, Ronny; Willassen, Nils P; Sylte, Ingebrigt. Comparative sequence and structure analysis reveal features of cold adaptation of an enzyme in the thermolysin family. Proteins: Structure, Function, and Bioinformatics 2006; Volum 62. ISSN 0887-3585.

Dahl, Svein G.; Sylte, Ingebrigt. From genomics to drug targets. Journal of Psychopharmacology 2006; Volum 20 (4). ISSN 0269-8811.s 95 - 99.

Ravna, Aina Westrheim; Jaronczyk, Malgorzata; Sylte, Ingebrigt. A homology model of SERT based on the LeuT(Aa) template. Bioorganic & Medicinal Chemistry Letters 2006; Volum 16. ISSN 0960-894X.s 5594 - 5597.

Adekoya, Olayiwola Adedotun; Willassen, Nils Peder; Sylte, Ingebrigt. The protein-protein interactions between SMPI and thermolysin studied by molecular dynamics and MM/PBSA calculations. Journal of Biomolecular Structure and Dynamics 2005; Volum 22 (5). ISSN 0739-1102.s 521 - 532.

Våbenø, Jon; Nielsen, Carsten Uhd; Steffansen, Bente; Lejon, Tore Sigvard; Sylte, Ingebrigt; Jørgensen, Flemming Steen; Luthman, Kristina. Conformational restrictions in ligand binding to the human intestinal di-/tripeptide transporter: implications for design of hPEPT1 targeted prodrugs. Bioorganic & Medicinal Chemistry 2005; Volum 13. ISSN 0968-0896.s 1977 - 1988.

Lindstad, Rune I; Sylte, Ingebrigt; Mikalsen, S O; Seglen, P O; Berg, Eli; Winberg, Jan-Olof. Pancreatic trypsin activates human promatrix metal loproteinase-2. Journal of Molecular Biology (JMB) 2005; Volum 350. ISSN 0022-2836.s 682 - 698.

Hjerde, Erik; Dahl, Svein G.; Sylte, Ingebrigt. Atypical and typical antipsychotic drug interactions with the dopamine D2 receptor. European Journal of Medicinal Chemistry 2005; Volum 40. ISSN 0223-5234.

Lindstad, Rune I.; Sylte, Ingebrigt; Mikalsen, Svein O.; Seglen, Per O.; Berg, Eli; Winberg, Jan O.. Pancreatic trypsin activates human promatrix metalloproteinase-2. Journal of Molecular Biology (JMB) 2005; Volum 350. ISSN 0022-2836.s 682 - 698.

Dahl, Svein Gunvald; Sylte, Ingebrigt. Molecular modelling of drug targets: The past, the present and the future. Basic & Clinical Pharmacology & Toxicology 2005; Volum 96. ISSN 1742-7835.s 151 - 155.

Dahl, Svein G.; Sylte, Ingebrigt; Ravna, Aina Westrheim. Structures and models of transporter proteins. Journal of Pharmacology and Experimental Therapeutics 2004; Volum 309 (3). ISSN 0022-3565.s 853 - 860.

Strzelczyk, Anna Agnieszka; Jaronczyk, Malgorzata; Chilmonczyk, Zdizlav; Mazurek, Pavel A; Chojnacka-Wojcik, Eva; Sylte, Ingebrigt. Intrinsic activity and comparative molecular dynamics of buspirone analogues at the 5-HT1A receptors. Biochemical Pharmacology 2004; Volum 67. ISSN 0006-2952.s 2219 - 2230.

Yang, Nannan; Mekonnen, Seble Merid; Solstad, Terese; Wikman, Mari; Kalaaji, manar; Sylte, Ingebrigt; Rekdal, Øystein. Enhanced tumor cell specificity by optimizing the relative position between aromatic and cationic residues in helical amphipathic peptides. 2003 ISBN 82-497-0155-0.

Ravna, Aina Westrheim; Sylte, Ingebrigt; Dahl, Svein G.. Molecular model of the neural dopamine transporter. Journal of Computer-Aided Molecular Design 2003; Volum 17. ISSN 0920-654X.s 367 - 382.

Ravna, Aina Westrheim; Sylte, Ingebrigt; Dahl, Svein G.. Molecular mechanisms of citalopram and cocaine interactions with the neurotransmitter transporter. Journal of Pharmacology and Experimental Therapeutics 2003; Volum 307 (1). ISSN 0022-3565.s 34 - 41.

Brandsdal, Bjørn Olav; Heimstad, Eldbjørg Sofie; Sylte, Ingebrigt; Smalås, Arne Oskar. Comparative Molecular Dynamics of Mesophilic and Psychrophilic Homologues Studied by 1.2 ns Simulations. Journal of Biomolecular Structure and Dynamics 1999; Volum 17. ISSN 0739-1102.s 493 - 506.s doi: 10.1080/07391102.1999.10508380.

Tollefsen, Knut-Erik; Cronin, Marc Timothy David; Evenseth, Linn; Firman, James W.; Iguchi, Taisen; Lalone, Carlie; Mellor, Claire; Sylte, Ingebrigt; Toyota, K.; Villeneuve, Daniel L.; Song, You. Endocrine Disruption in crustaceans – a “new” environmental challenge?. 20th Pollutant Responses in Marine Organism (PRIMO20) conference 2019-05-19 - 2019-05-22 2019.

Tollefsen, Knut Erik; Cronin, Marc Timothy David; Evensen, Øystein; Evenseth, Linn; Falciani, Francesco; Iguchi, Taisen; Lalone, Carlie; Li, Yang; Mellor, Claire; Perkins, Edward J.; Rundberget, Thomas; Salbu, Brit; Sylte, Ingebrigt; Villeneuve, Daniel L.; Vinas, N.; Song, You. AOP-informed assessment of Endocrine Disruption in freshwater crustaceans. 28th annual SETAC Europe Meeting 2018-05-13 - 2018-05-17 2018.

Tollefsen, Knut Erik; Cronin, Marc Timothy David; Evenseth, Linn; Firman, James W.; Iguchi, Taisen; Lalone, Carlie; Mellor, Claire; Sylte, Ingebrigt; Toyota, K.; Villeneuve, Daniel L.; Song, You. AOP-informed chemical screening, prioritization and risk assessment of arthropod Endocrine Disruptors. SETAC workshop on Hight-Throughput Screening 2018-04-16 - 2018-04-18 2018.

Song, You; Villeneuve, Daniel L.; Iguchi, Taisen; Rundberget, Thomas; Mellor, Claire; Cronin, Marc Timothy David; Evenseth, Linn; Sylte, Ingebrigt; Lalone, Carlie; Høgåsen, Tore; Falciani, Francesco; Garcia-Reyero, Natalia; Perkins, Edward J.; Evensen, Øystein; Xie, Li; Lyne, Fern; Gomes, Tania; Lillicrap, Adam David; Salbu, Brit; Tollefsen, Knut Erik. Development of invertebrate Adverse Outcome Pathways (AOPs) for mechanistically-based risk assessment. Nanjing Univeristy internal seminar 2017-04-23 - 2017.

Song, You; Villeneuve, Daniel L.; Iguchi, Taisen; Rodriguez-Sanchez, Neus; Rundberget, Thomas; Mellor, Claire; Cronin, Marc Timothy David; Evenseth, Linn; Sylte, Ingebrigt; Lalone, Carlie; Høgåsen, Tore; Falciani, Francesco; Garcia-Reyero, Natalia; Perkins, Edward J.; Evensen, Øystein; Xie, Li; Lyne, Fern; Gomes, Tania; Lillicrap, Adam David; Salbu, Brit; Tollefsen, Knut Erik. Development of invertebrate Adverse Outcome Pathways (AOPs) for mechanistically-based risk assessment. China’s 4th Symposium on Ecotoxicology 2017-04-24 - 2017.

Song, You; Villeneuve, Daniel L.; Iguchi, Taisen; Rundberget, Thomas; Mellor, Claire; Cronin, Marc Timothy David; Evenseth, Linn; Sylte, Ingebrigt; Lalone, Carlie; Hackermüller, Jörg; Høgåsen, Tore; Falciani, Francesco; Garcia-Reyero, Natalia; Perkins, Edward J.; Evensen, Øystein; Xie, Li; Lyne, Fern; Gomes, Tania; Lillicrap, Adam David; Salbu, Brit; Tollefsen, Knut Erik. Development of invertebrate Adverse Outcome Pathways (AOPs) for mechanistically-based risk assessment. International Symposium on Chemicals Risk Prediction and Management (ISCRPM-2017) 2017-04-25 - 2017.

Sæther, Thomas; Moldes-Anaya, Angel; Tungen, Jørn Eivind; Vik, Anders; Paulsen, Steinar M; Sylte, Ingebrigt; Hansen, Trond Vidar; Nebb, Hilde Irene. Anti-diabetic activity from marine lipids: new anti-diabetic drugs. Throne Holst Symposium 2016-05-19 - 2016-05-19 2016.

Mortensen, Åse-Karen; Jenssen, Bjørn Munro; Gabrielsen, Geir W.; Sylte, Ingebrigt; Heimstad, Eldbjørg Sofie. Competitive binding of persistent organic pollutants to the thyroid hormone transport protein transthyretin in Glaucous gull (Larus hypoerboreus). 2015.

Sæther, Thomas; Moldes-Anaya, Angel; Tungen, Jørn Eivind; Vik, Anders; Paulsen, Steinar Martin; Sylte, Ingebrigt; Hansen, Trond Vidar; Nebb, Hilde Irene. Anti-diabetic activity from marine lipids: new anti-diabetic drugs. EMBO Conference on Nuclear Receptors 2015-09-24 - 2015-09-28 2015.

Song, You; Cronin, Mark T.; Evensen, Øystein; Falciani, Francesco; Garcia-Reyero, Natalia; Høgåsen, Tore; Iguchi, Taisen; Langford, Katherine; Lalone, Carlie; Lillicrap, Adam David; Mellor, Claire; Perkins, Edward; Petersen, Karina; Salbu, Brit; Sylte, Ingebrigt; Thomas, Kevin V; Tollefsen, Knut Erik. EDRISK: Development of adverse outcome pathways for endocrine disruption in Daphnia magna. Scientific seminar at The Norwegian Environmental agency 2014-03-11 - 2014-03-11 2014.

Song, You; Cronin, Mark T.; Evensen, Øystein; Falciani, Francesco; Høgåsen, Tore; Iguchi, Taisen; Lalone, Carlie; Lillicrap, Adam David; Petersen, Karina; Perkins, Edward; Rundberget, Thomas; Salbu, Brit; Sylte, Ingebrigt; Thomas, Kevin V; Garcia-Reyero, Natalia; Tollefsen, Knut Erik. Development of adverse outcome pathways for endocrine disruption in Daphnia magna. SETAC Europe 24th annual meeting 2014-05-11 - 2014-05-15 2014.

Song, You; Antczak, Philipp; Cronin, Mark T.; Evenseth, Linn; Evensen, Øystein; Falciani, Francesco; Høgåsen, Tore; Iguchi, Taisen; Lalone, Carlie; Mellor, Claire; Perkins, Edward; Salbu, Brit; Sylte, Ingebrigt; Garcia-Reyero, Natalia; Villeneuve, Daniel; Tollefsen, Knut Erik. Development of adverse outcome pathways for endocrine disruption in Daphnia magna. SETAC North America Annual Meeting 2014-11-09 - 2014-11-13 2014.

Sylte, Ingebrigt; Sager, Georg. En pionerforsker. Ottar 2013 (297). ISSN 0030-6703.s 27 - 31.

Ravna, Aina Westrheim; Sylte, Ingebrigt. Drug design på data'n. Ottar 2013 (297). ISSN 0030-6703.s 22 - 26.

Tarpley, Reid S.; Adekoya, Olayiwola; Sylte, Ingebrigt; Odunuga, Odutayo O.. Large-scale expression and purification of active pseudolysin in Escherichia coli. The FASEB Journal 2013; Volum 27. ISSN 0892-6638.

Baglo, Yan; Gabrielsen, Mari; Sylte, Ingebrigt; Gederaas, Odrun Arna. Homology Modeling of Human <gamma>-Butyric Acid Transporters and the Binding of Pro-drugs 5-Aminolevulinic Acid and Methyl Aminolevulinic Acid used in Photodynamic Therapy. 15th Congress of the European Society for Photobiology 2013-09-02 - 2013-09-06 2013.

Baglo, Yan; Gabrielsen, Mari; Sylte, Ingebrigt; Gederaas, Odrun Arna. Homology modelling of human GABA transporters and the binding of prodrugs 5-aminolevulinic acid and its methyl ester used in photodynamic therapy. 3. Biostruct årsmøte, UiT 2012-08-30 - 2012-09-02 2012.

Gabrielsen, Mari; Sylte, Ingebrigt; Dahl, Svein G.; Ravna, aina westrheim. A short update on the structure of drug binding sites on neurotransmitter transporters. BMC Research Notes 2011; Volum 4. ISSN 1756-0500.s doi: 10.1186/1756-0500-4-559.

Baglo, Yan; Gabrielsen, Mari; Sylte, Ingebrigt. Homology modelling av GABA transporter: analyse av prodrug ALA og MAL uptak. NOFFOF årsmøte 2011 2011-11-18 - 2011.

Adekoya, Olayiwola; Sylte, Ingebrigt. Molecular interactions of ABT and matrix metalloproteinases. The FEBS Journal 2011; Volum 278. ISSN 1742-464X.s 322 - 322.

Chilmonczyk, Zdzislaw; Kossakowski, Jerzy; Walory, Jaroslaw; Koronkiewicz, Miroslawa; Sylte, Ingebrigt; Nowak, Gabriel; Bojarski, Andrezej J. Influence of new high affinity serotonin transporter ligands on cellular cAMP levels. Pharmacological Reports 2011; Volum 63 (2). ISSN 1734-1140.s 565 - 565.

Sjøli, Stian; Adekoya, Olayiwola; Jiang, Yang; Akselsen, O; Hansen, VT; Svineng, Gunbjørg; Sylte, Ingebrigt; Winberg, Jan-Olof. Novel Inhibitors of Matrix Metalloprotease-9 and-14. The FEBS Journal 2010; Volum 277. ISSN 1742-464X.s 265 - 265.

Wuxiuer, Yimingjiang; Cols, N; Gonzalez-Duarte, R; Ladenstein, R; Sylte, Ingebrigt; Winberg, Jan-Olof. Kinetic characterization of the Drosophila lebanonensis ADH T114V mutant. The FEBS Journal 2010; Volum 277. ISSN 1742-464X.s 265 - 265.

Chilmonczyk, Zdizlav; Jaronczyk, Malgorzata; Mazurek, AP; Sylte, Ingebrigt; Ravna, aina westrheim. Molecular targets for new antidepressant drugs. Pharmacological Reports 2008; Volum 60. ISSN 1734-1140.s 260 - 260.

Orhan, I; Khan, Mahmud Tareq Hassan; Aslan, S; Kartal, M; Sener, B; Sylte, Ingebrigt. Molecular docking studies on the alkaloid (+)-buxabenzamidienine from Buxus sempervirens L. with anticholinesterase effect. Planta Medica 2008; Volum 74 (9). ISSN 0032-0943.s 1166 - 1167.

Sylte, Ingebrigt. Molekylære mekanismer i jakten på nye legemidler - utvikling av nye antidepressive legemidler. Onsdagsmøte 2007-11-07 - 2007.

Sylte, Ingebrigt. Structural biology and visualization of drug targets. Workshop on Molecular Imaging 2007-04-27 - 2007.

Sylte, Ingebrigt. Structural visualization of molecular drug targets in the CNS. Conference on Imaging in Neuroscience 2007-04-26 - 2007-04-27 2007.

Gani, Osman A.B.S.M.; Sylte, Ingebrigt. The effect of E-Z isomerization of docosahexaeonic acid (DHA) double bonds on binding to nuclear receptors. Docking and scoring in structure guided drug design. 2006-04-05 - 2006-04-07 2006.

Jaronczyk, Malgorzata; Chilmonczyk, Zdizlav; Mazurek, AP; Dybala, M; Ravna, aina westrheim; Kristiansen, kurt; Sylte, Ingebrigt. Molecular mechanism of selective serotonin reuptake inhibitors (SSRI's) interactions with serotonin transporter. Journal of Peptide Science 2006; Volum 12. ISSN 1075-2617.s 186 - 186.

Khan, Mahmud Tareq Hassan; Sylte, Ingebrigt. Structural bioinformatics in the discovery of novel drugs. 9th Eurasis Conference on Chemical Sciences 2006-09-09 - 2006-09-13 2006.

Gani, Osman A.B.S.M.; Sylte, Ingebrigt. Molecular recognition of fatty acids by PPAR-alpha. Open day 2006. PhD-school in Molecular and Structural Biology 2006-11-15 - 2006.

Khan, Mahmud Tareq Hassan; Adekoya, Olayiwola Adedotun; Lorentzen, marit sjo; Willassen, Nils Peder; Smalås, Arne Oskar; Sylte, Ingebrigt. Molecular features and inhibition of the thermolysin family of enzymes. Open day 2006. PhD-school in Molecular and Structural Biology 2006-11-15 - 2006.

Adekoya, Olayiwola Adedotun; Dahl, Svein G.; Gabrielsen, Mari; Gani, Osman A.B.S.M.; Khan, Mahmud Tareq Hassan; Kristiansen, kurt; Sylte, Ingebrigt; Ravna, aina westrheim; Wuxiuer, Y; Sandberg, LS. The molecular modelling group. Open day 2006. PhD-school in Molecular and Structural Biology 2006-11-15 - 2006.

Jaronczyk, Malgorzata; Chilmonczyk, Zdizlav; Mazurek, AP; Dybala, M; Ravna, aina westrheim; Kristiansen, kurt; Sylte, Ingebrigt. Molecular mechanism of selective serotonin reuptake inhibitors (SSRI's)interactions with serotonin transporter. 29th European Peptide Symposium 2006-09-03 - 2006-09-08 2006.

Khan, Mahmud Tareq Hassan; Adekoya, Olayiwola Adedotun; Sylte, Ingebrigt. Sequence analysis of the assigned members of the M4 family of the peptidases compared to thermolysin, the prototype of the clan. Bioforum 2006 2006-06-07 - 2006-06-09 2006.

Gani, Osman A.B.S.M.; Sylte, Ingebrigt. Molecular recognition of fatty acids by PPAR-alpha. Structure-based Drug Design 2006-06-14 - 2006-06-16 2006.

Adekoya, Olayiwola Adedotun; Helland, Ronny; Willassen, Nils Peder; Sylte, Ingebrigt. Structural determinants for a cold adapted enzyme in the thermolysin family. The Norwegian Biochemical Society 41st Contact meeting 2005-01-13 - 2005-01-16 2005.

Strzelczyk, Anna Agnieszka; Jaronczyk, Malgorzata; Chilmonczyk, Zdizlav; Chojnacka-Wojcik, Eva; Sylte, Ingebrigt. The 5HT1A and 5HT2A serotonin receptors interactions with methylated buspirone analogues. The international conference sequence-structure-functions relationships. Thoretical and experimental approaches 2005-04-06 - 2005-04-10 2005.

Lindstad, Rune I; Sylte, Ingebrigt; Mikalsen, S O; Berg, Eli; Winberg, Jan-Olof. Pancreatic trypsin activates human promatrix metalloproteinase-2. NBS kontaktmøte 2005-01-13 - 2005-01-16 2005.

Ghani, Osman A.b.s.m; Adekoya, Olayiwola; Giuratob, L; Guccione, S; Winberg, Jan-Olof; Sylte, Ingebrigt. The catalytic mechanisms of short-chain dehydrogenases/ reductases. Horizons in Molecular Biology Decoding Nature: Hierarchy of Interactions, 2nd International PhD Student Symposium 2005-03-01 - 2005-03-02 2005.

Våbenø, Jon; Nielsen, Carsten Uhd; Ingebrigtsen, Truls Erik; Lejon, Tore Sigvard; Sylte, Ingebrigt; Jørgensen, Flemming Steen; Steffansen, Bente; Luthman, Kristina. Ketomethylene Based Dipeptidomimetics as Pro-Moieties for hPEPT1 Targeted Prodrugs. XVIII´th International Symposium on Medicinal Chemistry 2004-08-15 - 2004-08-19 2004.

Helland, Ronny; Adekoya, Olayiwola; Mekonnen, Seble Merid; Gjellesvik, Dag Rune; Edvardsen, Øyvind; Høgda, Kjell Arild; Grøttum, Karl Johan; Sylte, Ingebrigt; Smalås, Arne Oskar; Willassen, Nils Peder. Determination of Molecular Descriptors from Analysis of Sequence and Genome Data. Bioinformatics 2002 2002-04-04 - 2002-04-07 2002.

Loennechen, thrina; Lysaa, Roy A; Giverhaug, trude; Sylte, Ingebrigt; Mathisen, L-E; Aarbakke, Jarle. Nye styringsverktøy for tiopuriner i leukemi og transplantasjonsbehandling. Tidsskrift for Den norske legeforening 2002. ISSN 0029-2001.s 1107 - 1110.

Brandsdal, Bjørn Olav; Helland, Ronny; Sylte, Ingebrigt; Otlewski, J.; Smalås, Arne Oskar. Protein-protein recognition. Talking Proteins: An EMBO workhsop on sequence analysis, modelling and simulation 1998-09-01 - 1998.