Bilde av Mortensen, Elin Synnøve
Bilde av Mortensen, Elin Synnøve
Institutt for medisinsk biologi elin.s.mortensen@uit.no Tromsø

Elin Synnøve Mortensen


Professor og forskningsgruppeleder RAMP


  • Trygve Lofterød, Hanne Frydenberg, Vidar Gordon Flote, Anne Elise Eggen, Anne McTiernan, Elin Synnøve Mortensen m.fl.:
    Exploring the effects of lifestyle on breast cancer risk, age at diagnosis, and survival: the EBBA-Life study
    Breast Cancer Research and Treatment 2020 ARKIV / DOI
  • Erik Knutsen, Seyed Mohammad Lellahi, Miriam Ragle Aure, Silje Nord, Silje Fismen, Kenneth Bowitz Larsen m.fl.:
    The expression of the long NEAT1_2 isoform is associated with human epidermal growth factor receptor 2-positive breast cancers
    Scientific Reports 2020 ARKIV / DOI
  • Trygve Lofterød, Elin Synnøve Mortensen, Hawa Nalwoga, Tom Wilsgaard, Hanne Frydenberg, Terje Risberg m.fl.:
    Impact of pre-diagnostic triglycerides and HDL-cholesterol on breast cancer recurrence and survival by breast cancer subtypes
    BMC Cancer 2018 ARKIV / DOI
  • Stine Figenschau, Erik Knutsen, Ilona Urbarova, Christopher Graham Fenton, Bryan Elston, Maria Perander m.fl.:
    ICAM1 expression is induced by proinflammatory cytokines and associated with TLS formation in aggressive breast cancer subtypes
    Scientific Reports 2018 ARKIV / DOI
  • Hanne Frydenberg, Inger Thune, Trygve Lofterød, Elin Synnøve Mortensen, Anne Elise Eggen, Terje Risberg m.fl.:
    Pre-diagnostic high-sensitive C-reactive protein and breast cancer risk, recurrence, and survival
    Breast Cancer Research and Treatment 2016 DOI
  • Sveinung Wergeland Sørbye, Silje Fismen, Tore Jarl Gutteberg, Elin Synnøve Mortensen, Finn Egil Skjeldestad :
    Primary cervical cancer screening with an HPV mRNA test: a prospective cohort study
    BMJ Open 11. august 2016 ARKIV / FULLTEKST / DOI
  • Stine Linn Figenschau, Silje Fismen, Kristin Andreassen Fenton, Christopher Graham Fenton, Elin Synnøve Mortensen :
    Tertiary lymphoid structures are associated with higher tumor grade in primary operable breast cancer patients
    BMC Cancer 2015 ARKIV / DOI
  • Sveinung Wergeland Sørbye, Silje Fismen, Tore Jarl Gutteberg, Elin Synnøve Mortensen, Finn Egil Skjeldestad :
    HPV mRNA is more specific than HPV DNA in triage of women with minor cervical lesions
    PLOS ONE 18. november 2014 FULLTEKST / ARKIV / DOI
  • Natalya Seredkina, Johan van der Vlag, Jo Berden, Elin Synnøve Mortensen, Ole Petter Rekvig :
    Lupus Nephritis: Enigmas, Conflicting Models and an Emerging Concept
    Molecular medicine (Cambridge, Mass. Print) 2013 ARKIV / DOI
  • Sveinung Wergeland Sørbye, Silje Fismen, Tore Jarl Gutteberg, Elin Synnøve Mortensen, Finn Egil Skjeldestad :
    HPV mRNA testing in triage of women with ASC-US cytology may reduce the time for CIN2+ diagnosis compared with repeat cytology
    Current pharmaceutical design 2013 ARKIV / DOI
  • Silje Fismen, Dhivya Thiyagarajan, Natalya Seredkina, Henrik Nielsen, Søren Jacobsen, Thomas Elung-Jensen m.fl.:
    Impact of the Tumor Necrosis Factor Receptor-Associated Protein 1 (Trap1) on Renal DNaseI Shutdown and on Progression of Murine and Human Lupus Nephritis
    American Journal of Pathology 2013 DOI
  • Ole Petter Rekvig, Chaim Putterman, Cinzia Casu, Hua-Xin Gao, Anna Ghirardello, Elin Synnøve Mortensen m.fl.:
    Autoantibodies in lupus: Culprits or passive bystanders?
    Autoimmunity Reviews 2012 DOI
  • Dhivya Thiyagarajan, Silje Fismen, Natalya Seredkina, Søren Jacobsen, Thomas Elung-Jensen, Anne-Lise Kamper m.fl.:
    Silencing of Renal DNaseI in Murine Lupus Nephritis Imposes Exposure of Large Chromatin Fragments and Activation of Toll Like Receptors and the Clec4e
    PLOS ONE 2012 ARKIV / DOI
  • Ole Petter Rekvig, Elin Synnøve Mortensen :
    Immunity and autoimmunity to dsDNA and chromatin - the role of immunogenic DNA-binding proteins and nuclease deficiencies
    Autoimmunity 2012 DOI
  • Annica Hedberg, Elin Mortensen, Ole Petter Rekvig :
    Chromatin as a target antigen in human and murine lupus nephritis
    Arthritis Research & Therapy 2011 DOI
  • Annica Hedberg, Silje Fismen, Kristin Andreassen Fenton, Christopher Graham Fenton, Bjarne Østerud, Elin Mortensen m.fl.:
    Heparin Exerts a Dual Effect on Murine Lupus Nephritis by Enhancing Enzymatic Chromatin Degradation and Preventing Chromatin Binding in Glomerular Membranes
    Arthritis and Rheumatism 2011 DOI
  • Sveinung Wergeland Sørbye, Marc Arbyn, Silje Fismen, Tore Jarl Gutteberg, Elin Mortensen :
    Triage of Women with Low-Grade Cervical Lesions - HPV mRNA Testing versus Repeat Cytology
    PLOS ONE 2011 ARKIV / DOI
  • Sveinung Wergeland Sørbye, Marc Arbyn, Silje Fismen, Tore Jarl Gutteberg, Elin Synnøve Mortensen :
    HPV E6/E7 mRNA Testing Is More Specific than Cytology in Post-Colposcopy Follow-Up of Women with Negative Cervical Biopsy
    PLOS ONE 2011 ARKIV / DOI
  • Silje Fismen, Elin Mortensen, Ole Petter Rekvig :
    Nuclease deficiencies promote end-stage lupus nephritis but not nephritogenic autoimmunity in (NZBxNZW) F1 mice
    Immunology and Cell Biology 2011 DOI
  • Kim Erlend Mortensen, LN Conley, Ingvild Nygård, Peter Sørensen, Elin Mortensen, C Bendixen m.fl.:
    Increased sinusoidal flow is not the primary stimulus to liver regeneration
    Comparative Hepatology 2010 ARKIV / DOI
  • Silje Fismen, Elin Mortensen, Ole Petter Rekvig :
    Nuclease deficiencies promote end-stage lupus nephritis but not nephritogenic autoimmunity in (NZB x NZW) F1 mice
    Immunology and Cell Biology 2010 DOI
  • Annica Hedberg, Silje Fismen, Kristin Andreassen Fenton, Elin Mortensen, Ole Petter Rekvig :
    Deposition of chromatin-IgG complexes in skin of nephritic MRL-lpr/lpr mice is associated with increased local matrix metalloprotease activities
    Experimental Dermatology 2010 DOI
  • Sveinung Wergeland Sørbye, Silje Fismen, Tore Jarl Gutteberg, Elin Mortensen :
    Triage of Women with Minor Cervical Lesions: Data Suggesting a "Test and Treat" Approach for HPV E6/E7 mRNA Testing
    PLOS ONE 2010 ARKIV / DOI
  • Sveinung Wergeland Sørbye, Silje Fismen, Tore Jarl Gutteberg, Elin Mortensen :
    HPV mRNA test in women with minor cervical lesions: Experience of the University Hospital of North Norway
    Journal of Virological Methods 2010 ARKIV / DOI
  • Silje Fismen, Annica Hedberg, Kristin Andreassen Fenton, S Jacobsen, E Krarup, AL Kamper m.fl.:
    Circulating chromatin-anti-chromatin antibody complexes bind with high affinity to dermo-epidermal structures in murine and human lupus nephritis
    Lupus 2009 DOI
  • Kristin Andreassen Fenton, Silje Fismen, Annica Hedberg, Natalya Seredkina, Christopher Graham Fenton, Elin Mortensen m.fl.:
    Anti-dsDNA Antibodies Promote Initiation, and Acquired Loss of Renal Dnase1 Promotes Progression of Lupus Nephritis in Autoimmune (NZBxNZW)F1 mice
    PLOS ONE 2009 ARKIV / DOI
  • Elin Mortensen, Ole Petter Rekvik :
    Nephritogenic Potential of Anti-DNA Antibodies against Necrotic Nucleosomes
    Journal of the American Society of Nephrology 2009 DOI
  • Elin Synnøve Mortensen, Michael Shelley Kearney :
    Meconium Aspiration in the Midtrimester Fetus: An Autopsy Study
    Pediatric and Developmental Pathology 2009 DOI
  • Elin Mortensen, TO Rognum, Bjørn Straume, Leif Jørgensen :
    Frequency of acute asymptomatic myocardial infarction and an estimate of infarct age in cases of abrupt sudden death observed in a forensic autopsy material
    Journal of Cellular and Molecular Medicine 2008 DOI
  • signy Bendiksen, Elin Mortensen, randi Olsen, Kristin Andreassen Fenton, manar Kalaaji, Leif Jørgensen m.fl.:
    Glomerular expression of large polyomavirus T antigen in binary tet-off regulated transgenic mice induces apoptosis, release of chromatin and initiates a lupus-like nephritis
    Molecular Immunology 2008 DOI
  • Elin Mortensen, Kristin Andreassen Fenton, Ole Petter Rekvik :
    Lupus nephritis - The central role of nucleosomes revealed
    American Journal of Pathology 2008 DOI
  • Elin Mortensen, Torleiv O Rognurn, Torleiv Ole Rognum, Bjørn Straume, Leif Jørgensen, L Jorgensen :
    Evidence at autopsy of spasm in the distal right coronary artery in persons with coronary heart disease dying suddenly
    Cardiovascular pathology 2007 DOI
  • manar Kalaaji, Kristin Andreassen Fenton, Elin Mortensen, randi Olsen, G Sturfelt, P Alm m.fl.:
    Glomerular apoptotic nucleosomes are central target structures for nephritogenic antibodies in human SLE nephritis
    Kidney International 2007 DOI
  • Silje Fismen, Ole Petter Rekvik, Elin Mortensen :
    Pathogenesis of SLE dermatitis - a reflection of the process in SLE nephritis?
    Current Rheumatology Reviews 2007
  • Manar Kalaaji, Elin Mortensen, Leif Jørgensen, Randi Olsen, Ole Petter Rekvik :
    Nephritogenic lupus antibodies recognize glomerular basement membrane-associated chromatin fragments released from apoptotic intraglomerular cells
    American Journal of Pathology 2006
  • Kristin Andreassen Fenton, Stine Figenschau, Elin Synnøve Mortensen :
    ICAM1 er uttrykt i trippel negative brystkreftceller og vev
    Best Practice Nordic 2018
  • Sveinung Wergeland Sørbye, Silje Fismen, Tore Jarl Gutteberg, Elin Mortensen, Finn Egil Skjeldestad :
    HPV mRNA testing is more specific than HPV DNA testing in triage of women with minor cervial lesions
    2013 OMTALE / ARKIV
  • Sveinung Wergeland Sørbye, Silje Fismen, Elin Synnøve Mortensen, Tore Jarl Gutteberg, Finn Egil Skjeldestad :
    HPV mRNA and cytology cotesting in primary cervical caner screening by age
    2012
  • Sveinung Wergeland Sørbye, Silje Fismen, Elin Synnøve Mortensen, Tore Jarl Gutteberg :
    HPV-test i forebygging av livmorhalskreft
    Tidsskrift for Den norske legeforening 21. februar 2012 FULLTEKST / DOI
  • Sveinung Wergeland Sørbye, Silje Fismen, Elin Synnøve Mortensen, Tore Jarl Gutteberg, Finn Egil Skjeldestad :
    Post-colposcopy follow-up of women with negative cervical biopsy - a prospecitve study
    2012
  • Sveinung Wergeland Sørbye, Silje Fismen, Tore Jarl Gutteberg, Elin Synnøve Mortensen, Finn Egil Skjeldestad :
    HPV mRNA test in primry screening of women 20-34 years
    2011 ARKIV
  • Elin Mortensen :
    LUPUS NEPHRITIS, AN ACQUIRED ERROR OF CHROMATIN METABOLISM IN AUTOIMMUNE (NZBXNZW)F1 MICE
    Clinical and Experimental Rheumatology 2011
  • Sveinung Wergeland Sørbye, Silje Fismen, Tore Jarl Gutteberg, Elin Synnøve Mortensen, Finn Egil Skjeldestad :
    HPV mRNA testing - longterm follow-up
    2011
  • Elin Synnøve Mortensen, Silje Fismen :
    Forsvarlig bruk av HPV-test
    Dagens medisin 26. februar 2011 FULLTEKST
  • Sveinung Wergeland Sørbye, Silje Fismen, Tore Jarl Gutteberg, Elin Synnøve Mortensen :
    HPV-testing og livmorhalskreft
    Tidsskrift for Den norske legeforening 18. februar 2011 FULLTEKST / DOI
  • Sveinung Wergeland Sørbye, Silje Fismen, Tore Jarl Gutteberg, Elin Synnøve Mortensen :
    Redegjør for HPV-resultater
    Dagens medisin 25. januar 2011 FULLTEKST / ARKIV
  • Elin Mortensen, TO Rognum, Bjørn Straume, Leif Jørgensen :
    Frequency and Time of Onset of Acute Myocardial Infarction in Sudden unexpected Deaths in a Forensic Autopsy Material
    2007
  • Elin Mortensen, TO Rognum, Bjørn Straume, Leif Jørgensen :
    Evidence at autopsy of spasm in the right distal coronary artery in cases of coronary heart disease with sudden death
    Atherosclerosis Supplements 2007
  • Elin Mortensen, Torleiv Rognum, Bjørn Straume, Leif Jørgensen :
    Cause, frequency and time of onset of asymptomatic acute myocardial infarction in abrupt unexpected deaths in a forensic autopsy material
    Virchows Archiv 2007
  • Elin Mortensen :
    Use of rapid CK on frozen sections
    2005

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    Publikasjoner utenom Cristin


    Publikasjonsliste 2007-2011
    .   

    1. Kalaaji M, Fenton K, Mortensen E, Olsen R, Sturfelt, G, Alm P, Rekvig OP. Glomerular apoptotic nucleosomes are central target structures for nephritogenic antibodies in human SLE nephritis. Kidney Int., 2007,Apr;71(7):664-72
    2. Fismen S., Rekvig OP., Mortensen ES., Pathogenesis of SLE dermatitis - A Reflection of the Process in SLE nephritis? Current Rheumatology Reviews, 2007, 3, 159-65
    3. Mortensen ES, Rognum TO, Straume B, Jørgensen L. Evidence at autopsy of spasm in the distal right coronary artery in persons with coronary heart disease dying suddenly.  Cardiovasc Pathol. 2007 Nov-Dec;16(6):336-43. Epub 2007 Jul 25
    4. Mortensen ES, Fenton KA, Rekvig OP. Lupus nephritis: the central role of nucleosomes revealed. Am J Pathol. 2008 Feb;172(2):275-83. Epub 2008 Jan 10.
    5. Mortensen ES, Rognum TO, Straume B, Jørgensen L. Frequency of acute asymptomatic myocardial infarction and an estimate of infarct age in cases of abrupt sudden death observed in a forensic autopsy material. J Cell Mol Med. 2008 Oct;12(5B):2119-29. Epub 2008 Jan 19.
    6. BendiksenS, Mortensen ES, Olsen R, Fenton KA, Kalaaji M, Jørgensen L, Rekvig OP. Glomerular expression of large polyomavirus T antigen in binary tet-off regulated transgenic mice induces apoptosis, release of chromatin and initiates a lupus-like nephritis. Mol Immunol. 2008;45:728-39.
    7. Mortensen E, and Rekvig OP. Nephritogenic potential of anti-DNA antibodies against necrotic nucleosomes. Invited Manuscript. Review J Am Soc Nephrol, 20(4):696-704, 2009.
    8. Fenton K, Fismen S, Hedberg A, Seredkina N, Fenton C, Mortensen ES, Rekvig OP. Anti-dsDNA antibodies promote initiation, and acquired loss of renal Dnase1 promotes progression of lupus nephritis in autoimmune (NZBxNZW)F1 mice. PLoS One. 2009, 29;4(12):e8474
    9. Fismen S, Hedberg A, Fenton K, Jacobsen S, Krarup E, Kamper A, Rekvig O, Mortensen E. Circulating chromatin-anti-chromatin antibody complexes bind with high affinity to dermo-epidermal structures in murine and human lupus nephritis. 2009. Lupus 18(7): 597-607
    10. Mortensen ES, Kearney M. Meconium aspiration in mid trimester fetus:             an autopsy study. Pediatr Dev Pathol, 2009, Nov.Dec;12(6):438-42
    11. Fismen S, Mortensen ES, Rekvig. OP. Nuclease deficiencies promotes end-stage lupus nephritis but not nephritogenic autoimmunity. Review, Immunol Cell Biol, 2010 June 15
    12. Hedberg A,  Fismen S, Fenton  KA, Mortensen ES, Rekvig OP. Deposition of chromatin-IgG complexes in skin of nephritic MRL-lpr/lpr mice is associated with increased local matrix metalloprotease activities. Exp Dermatol. 2010, Aug 19(8):e265-74
    13. Hedberg A, Fismen S, Fenton KA, Østerud B, Mortensen ES, Rekvig OP. Heparin exerts dual effect on murine lupus nephritis by enhancing enzymatic chromatin degradation and preventing chromatin binding in glomerular membranes. Arthritis Rheum, 2011, Apr;63(4):1065-75.doi:10.1002/art.30211
    14. Mortensen KE, Conley LN, Nygaard I, Soerensen P, Mortensen E, Bendixen C, Revhaug A. Increased sinusoidal flow is not the primary stimulus to liver regeneration.Comp Hepatol., 2010, 20;9:2  
    15. Wergeland SS, Fismen S, Gutteberg TJ, Mortensen E.  HPV mRNA test in women with minor cervical lesions:  experiences from the University Hospital of North Norway. Journal of Virological Methods. 2010 oct;169(1)219-22 Epub 2010 Jul 16. PMID:20638416
    16. Wergeland SS, Fismen S, Gutteberg TJ, Mortensen E. Triage of Women with Minor Cervical Lesions: Data Suggesting a “Test and Treat” Approach for HPV E6/E7 mRNA Testing. Plos One 2010 sept 13;5(9):e12724, PMID:20856930
    17. Hedberg A, Mortensen ES, Rekvig OP. Chromatin as a target antigen in human and murine lupus nephritis.  Arthritis Res Ther. 2011, apr 18;13(2):214 (epub ahead of print).
    18. Sørbye SW, Arbyn M, Fismen S, Gutteberg TJ, Mortensen ES Triage of Women with Low-Grade Cervical Lesions - HPV mRNA Testing versus Repeat Cytology. PLoS ONE 2011 6(8): e24083. doi:10.1371/journal.pone.0024083
    19. Sørbye SW, Arbyn M, Fismen S, Gutteberg T, Mortensen ES. Follow-up of women with negative cervical biopsy - HPV E6/E7 mRNA testing versus cytology. PLoS One. 2011 okt.