Arnfinn Sundsfjord
Professor i Medisinsk Mikrobiologi
Theresa Wagner,
Benjamin P Howden,
Arnfinn Sundsfjord,
Kristin Hegstad
:
Transiently silent acquired antimicrobial resistance: an emerging challenge in susceptibility testing
Theresa Wagner,
Jessin Janice,
Marc Schluz,
Susan Ballard,
Anders da Silva,
Geoffrey W Coombs
m.fl.:
Reversible vancomycin susceptibility within emerging ST1421 Enterococcus faecium strains is associated with rearranged vanA-gene clusters and increased vanA plasmid copy number
International Journal of Antimicrobial Agents 2023 DOI
Marit Hetland,
Jane Hawkey,
Eva Bernhoff,
Ragna-Johanne Bakksjø,
Håkon Kaspersen,
Siren Rettedal
m.fl.:
Within-patient and global evolutionary dynamics of Klebsiella pneumoniae ST17
Microbial Genomics 2023 DOI
Kirsten Midttun Gravningen,
Oliver Kacelnik,
Egil Lingaas,
Torunn Pedersen,
Bjørn Gunnar Iversen,
Anne Mette Asfeldt
m.fl.:
Pseudomonas aeruginosa countrywide outbreak in hospitals linked to pre-moistened non-sterile washcloths, Norway, October 2021 to April 2022
Kenneth Lindstedt,
Dorota Julia Buczek,
Torunn Annie Pedersen,
Erik Hjerde,
Niclas Peter Raffelsberger,
Yutaka Suzuki
m.fl.:
Detection of Klebsiella pneumoniae human gut carriage: a comparison of culture, qPCR, and whole metagenomic sequencing methods
Faheema Ebrahim Choonara,
Bjørg Haldorsen,
Jessin Janice,
Joshua Mbanga,
Isaac Ndhlovu,
Osborne Saulosi
m.fl.:
Molecular Epidemiological Characterisation of ESBL- and Plasmid-Mediated AmpC-Producing Escherichia coli and Klebsiella pneumoniae at Kamuzu Central Hospital, Lilongwe, Malawi
Faheema E. Choonara,
Bjørg Haldorsen,
Isaac Ndhlovu,
Osborne Saulosi,
Tarsizio Maida,
Fanuel Lampiao
m.fl.:
Antimicrobial susceptibility profiles of clinically important bacterial pathogens at the Kamuzu Central Hospital in Lilongwe, Malawi
Caillan Crowe-McAuliffe,
Victoriia Murina,
Kathryn Jane Turnbull,
Susanne Huch,
Marje Kasari,
Hiraku Takada
m.fl.:
Structural basis for PoxtA-mediated resistance to phenicol and oxazolidinone antibiotics
Mushtaq T.S. Al-Rubaye,
Jessin Janice,
Jørgen Vildershøj Bjørnholt,
Aleksandra Jakovljev,
Maria Elisabeth Hultström,
Arnfinn Sundsfjord
m.fl.:
Novel genomic islands and a new vanD-subtype in the first sporadic VanD-type vancomycin resistant enterococci in Norway
Jessin Janice,
Nicholas Agyepong,
Alex Owusu-Ofori,
Usha Govinden,
Sabiha Essack,
Ørjan Samuelsen
m.fl.:
Carbapenem resistance determinants acquired through novel chromosomal integrations in extensively drug-resistant pseudomonas aeruginosa
Niclas Peter Raffelsberger,
Marit Andrea Klokkhammer Hetland,
Kristian Svendsen,
Lars Småbrekke,
Iren Høyland Löhr,
Lotte Andreassen
m.fl.:
Gastrointestinal carriage of Klebsiella pneumoniae in a general adult population: a cross-sectional study of risk factors and bacterial genomic diversity
Marit Østlyngen Riibe,
Sveinung Wergeland Sørbye,
Gunnar Skov Simonsen,
Arnfinn Sundsfjord,
Josef Ekgren,
Jan Martin Maltau
:
Risk of cervical intraepithelial neoplasia grade 3 or higher (CIN3+) among women with HPV-test in 1990–1992, a 30-year follow-up study
Abel F.N.D. Phiri,
Akebe Luther King Abia,
Daniel Gyamfi Amoako,
Rajab Mkakosya,
Arnfinn Sundsfjord,
Sabiha Essack
m.fl.:
Burden, antibiotic resistance, and clonality of shigella spp. Implicated in community-acquired acute diarrhoea in Lilongwe, Malawi
Calvina Estalva,
Tomas Zimba,
Sekyere John,
Usha Govinden,
Hafizah Y. Chenia,
Gunnar Skov Simonsen
m.fl.:
High prevalence of multidrug resistant ESBL- and plasmid mediated AmpC-producing clinical isolates of Escherichia coli at Maputo Central Hospital, Mozambique
Aasmund Fostervold,
Marit Andrea Klokkhammer Hetland,
Ragna-Johanne Bakksjø,
Eva Bernhoff,
Kathryn E. Holt,
Ørjan Samuelsen
m.fl.:
A nationwide genomic study of clinical Klebsiella pneumoniae in
Norway 2001–15: introduction and spread of ESBLs facilitated by
clonal groups CG15 and CG307
Fredrik Håkonsholm,
Marit Andrea Klokkhammer Hetland,
Cecilie Smith Svanevik,
Arnfinn Sundsfjord,
Bjørn Tore Lunestad,
Nachiket Marathe
:
Antibiotic sensitivity screening of Klebsiella spp. and Raoultella spp. isolated from marine bivalve molluscs reveal presence of CTX-M-producing K. pneumoniae
Theresa Wagner,
Jessin Janice,
Audun Sivertsen,
Ingegerd Sjögren,
Arnfinn Sundsfjord,
Kristin Hegstad
:
Alternative vanHAX promoters and increased vanA-plasmid copy number resurrect silenced glycopeptide resistance in Enterococcus faecium
Veronika Vorobieva,
Anne-Sofie Furberg,
Hans-Christian Slotved,
Tatiana Bazhukova,
Bjørg Haldorsen,
Dominique A Caugant
m.fl.:
Epidemiological and molecular characterization of Streptococcus pneumoniae carriage strains in pre-school children in Arkhangelsk, northern European Russia, prior to the introduction of conjugate pneumococcal vaccines
Sara Lino Faife,
Tomas Zimba,
John Osei Sekyere,
Usha Govinden,
Hafizah Y. Chenia,
Gunnar Skov Simonsen
m.fl.:
β-lactam and fluoroquinolone resistance in Enterobacteriaceae from imported and locally-produced chicken in Mozambique
Alison Holmes,
Mark Holmes,
Thomas Gottlieb,
Lance B Price,
Arnfinn Sundsfjord
:
End non-essential use of antimicrobials in livestock
The BMJ 2019 DOI
Nicholas Agyepong,
Usha Govinden,
Alex Owusu-Ofori,
Daniel Gyamfi Amoako,
Mushal Allam,
Jessin Janice James Peter
m.fl.:
Genomic characterization of multidrug-resistant ESBL-producing Klebsiella pneumoniae isolated from a Ghanaian teaching hospital
Ilya Nikolaevich Zykov,
Niels Frimodt-Møller,
Lars Småbrekke,
Arnfinn Sundsfjord,
Ørjan Samuelsen
:
Efficacy of mecillinam against clinical multidrug-resistant Escherichia coli in a murine urinary tract infection model
Torunn Annie Pedersen,
John Osei Sekyere,
Usha Govinden,
Krishnee Moodley,
Audun Sivertsen,
Ørjan Samuelsen
m.fl.:
Spread of plasmid-encoded NDM-1 and GES-5 carbapenemases among extensively drug-resistant and pandrug-resistant clinical enterobacteriaceae in durban, South Africa
Antimicrobial Agents and Chemotherapy 2018 DOI
Bjørg Haldorsen,
Christian G Giske,
Dennis S Hansen,
Kristjan Orri Helgason,
Gunnar Kahlmeter,
Iren Høyland Löhr
m.fl.:
Performance of the EUCAST disc diffusion method and two MIC methods in detection of Enterobacteriaceae with reduced susceptibility to meropenem: the NordicAST CPE study.
Lourenco Marcos Chirindze,
Tomas F. Zimba,
John Osei Sekyere,
Usha Govinden,
Hafizah Y. Chenia,
Arnfinn Sundsfjord
m.fl.:
Faecal colonization of E. coli and Klebsiella spp. producing extended-spectrum beta-lactamases and plasmid-mediated AmpC in Mozambican university students
Ilya Nikolaevich Zykov,
Ørjan Samuelsen,
Lotte Jakobsen,
Lars Småbrekke,
Dan I. Andersson,
Arnfinn Sundsfjord
m.fl.:
Pharmacokinetics and pharmacodynamics of fosfomycin and its activity against extended-spectrum-lactamase-, plasmid-mediated AmpC-, and carbapenemase-producing escherichia coli in a murine urinary tract infection model
Ørjan Samuelsen,
Søren Overballe-Petersen,
Jørgen Bjørnholt,
Sylvain Brisse,
Michel Doumith,
Neil Woodford
m.fl.:
Molecular and epidemiological characterization of carbapenemase-producing Enterobacteriaceae in Norway, 2007 to 2014
Silje Jørgensen,
Arne Vasli Søraas,
Lotte Pia Stenfors Arnesen,
Truls Michael Leegaard,
Arnfinn Sundsfjord,
Pål Jenum
:
A comparison of extended spectrum beta-lactamase producing Escherichia coli from clinical, recreational water and wastewater samples associated in time and location
Silje Jørgensen,
Arne Vasli Søraas,
Lotte Pia Stenfors Arnesen,
Truls Michael Leegaard,
Arnfinn Sundsfjord,
Pål Jenum
:
First environmental sample containing plasmid-mediated colistin-resistant ESBL-producing Escherichia coli detected in Norway
Silje Jørgensen,
Arne Vasli Søraas,
Arnfinn Sundsfjord,
Knut Liestøl,
Truls Michael Leegaard,
Pål Jenum
:
Fecal carriage of extended spectrum β-lactamase producing Escherichia coli and Klebsiella pneumoniae after urinary tract
infection - A three year prospective cohort
study
Alison H Holmes,
Luke S P Moore,
Arnfinn Sundsfjord,
Martin Steinbakk,
Sadie Regmi,
Abhilasha Karkey
m.fl.:
Understanding the mechanisms and drivers of antimicrobial resistance
The Lancet 2016 DOI
Marit Hetland,
Mia Angelique Winkler,
Thomas D Stanton,
Ryan R. Wick,
Margaret MC Lam,
Aasmund Fostervold
m.fl.:
Klebsiella pneumoniae ecology and antimicrobial resistance in a One Health perspective
2023
Fredrik Håkonsholm,
Arnfinn Sundsfjord,
Cecilie Smith Svanevik,
Bjørn Tore Lunestad,
Nachiket Marathe
:
Klebsiella pneumoniae in the marine setting – a challenge for seafood safety?
2023
Klara Stensvåg,
Arnfinn Sundsfjord,
Pål Jarle Johnsen,
Hanna-Kirsti S. Leiros,
Lise Nordgård
:
CANS - Centre for New Antibacterial Strategies
2022 PROSJEKT
Yngvild Wasteson,
Henning Sørum,
Bjørn-Arne Lindstedt,
Arnfinn Sundsfjord,
Hans Geir Eiken,
Erik Joner
m.fl.:
CORNELIA – Antimicrobial Resistance (AMR) in One Health Interfaces
2021 PROSJEKT
Bjørg C Haldorsen,
Erika Matuschek,
Jenny Åhman,
Gunnar Kahlmeter,
Arnfinn Sundsfjord,
Kristin Hegstad
:
Performance of the EUCAST disc diffusion method and gradient tests in detection of linezolid susceptibility in Enterococcus faecalis and Enterococcus faecium
2021
Theresa Wagner,
Jessin Janice James Peter,
Marc Schulz,
Susan A. Ballard,
Anders Goncalves da Silva,
Geoffrey W Coombs
m.fl.:
Australian vancomycin variable E. faecium ST1421 revert to resistance by the use of an alternative vanHAX promoter and increased vanA-plasmid copy number
2021
Yngvild Wasteson,
Henning Sørum,
Bjørn-Arne Lindstedt,
Adriana Dorota Osinska,
Arnfinn Sundsfjord,
Hans Geir Eiken
m.fl.:
CORNELIA – Antimicrobial Resistance (AMR) in One Health Interfaces
2021
Paul Christoffer Lindemann,
Karianne Wiger Gammelsrud,
Iren Høyland Löhr,
Per Espen Akselsen,
Morten Lindbæk,
Arnfinn Sundsfjord
:
Valg av antibiotika - viktig endring i prøvesvar fra mikrobiologen
Tidsskrift for Den norske legeforening 2019 DOI
Nicholas Agyepong,
Usha Govinden,
Alex Owusu-Ofori,
Mushal Allam,
Arshad Ismail,
Torunn Annie Pedersen
m.fl.:
Whole-genome sequences of two multidrug-resistant acinetobacter baumannii strains isolated from patients with urinary tract infection in Ghana
Microbiology Resource Announcements (MRA) 2019 DOI
Theresa Wagner,
Jessin Janice,
Audun Sivertsen,
Ingegerd Sjögren,
Arnfinn Sundsfjord,
Kristin Hegstad
:
The bag of tricks of vancomycin variable enterococci:
an alternative constitutive vanHAX-promoter, varying copy numbers and transferable resistance
2019
Mushtaq Talib Shawi Al-Rubaye,
Jessin Janice,
Iren Høyland Löhr,
Arnfinn Sundsfjord,
Kristin Hegstad
:
THE FIRST VANE VANCOMYCIN RESISTANT ENTEROCOCCUS FAECALIS IN NORWAY
2019
Mushtaq Talib Shawi Al-Rubaye,
Jessin Janice,
Jørgen Vildershøj Bjørnholt,
Oliver Kacelink,
Biørg C. Haldorsen,
Randi M. Nygaard
m.fl.:
POPULATION STRUCTURE OF THE NORWEGIAN VANCOMYCIN RESISTANT AND SENSITIVE ENTEROCOCCI 2010-2015
2019
A Basic,
Erika Matuschek,
O Karatuna,
Bjørg C Haldorsen,
Kristin Hegstad,
Jenny Åhman
m.fl.:
Evaluation of gradient tests for vancomycin MIC determination in Enterococcus faecalis and Enterococcus faecium. Effect of incubation for 16-20 hours vs. 24 hours
2019
Lyn Middleton,
F Lampiao,
Tomas F. Zimba,
SM Muzime,
Gunnar Skov Simonsen,
Lars Småbrekke
m.fl.:
Sharing Knowledge Transforming Societies. The Norhed Programme 2013-2020
African Minds 2019
Jessin Janice James Peter,
Joachim Hegstad,
Ellen H. Josefsen,
Arnfinn Sundsfjord,
Kristin Hegstad
:
Increased prevalence of linezolid resistance mong clinical enterococci in Norway mainly due to spread of optrA E. faecalis
2019
Theresa Wagner,
Audun Sivertsen,
Jessin Janice,
Ingegerd Sjögren,
Arnfinn Sundsfjord,
Kristin Hegstad
:
Vancomycin variable resistance may occur through creation of a novel constitutive vanHAX-promoter by illegitimate recombination
2018
Jessin Janice James Peter,
Ellen H. Josefsen,
Arnfinn Sundsfjord,
Kristin Hegstad
:
Increased prevalence of linezolid resistance among clinical enterococci in Norway.
2018
Maria Chiara Di Luca,
Dagfinn Skaare,
Bettina Aasnæs,
Arnfinn Sundsfjord,
Ørjan Samuelsen
:
Identification of a novel IMI carbapenemase variant (IMI-9) in Enterobacter cloacae complex
International Journal of Antimicrobial Agents 2016 DOI
Henning Onarheim,
RAGNVALD LJONES BREKKE,
Rafael Alexander Mo Leiva,
Dorthea Hagen Oma,
Helge Kolstad,
Ørjan Samuelsen
m.fl.:
H. Onarheim og medarbeidere svarer
Tidsskrift for Den norske legeforening 2016 DOI
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Forskningsinteresser
- Antibiotika, antibiotikaresistente bakterier og evolusjon
- Klebsiella pneumoniae (Kp) er en sentral aktør i den globale spredningen av antibiotikaresistens. Våre studier involverer komparative molekylære epidemiologiske studier (helgenomsekvensering og metagenomikk) av Kp fra ulike økologiske nisjer inkludert mennesker og dyr, feno- og genotypiske assosiasjoner i patogenitet og antibiotikaresistens (genomassosiasjonsstudier og maskinlæring), samt prekliniske effekstudier av bakterievirus (bakteriofager) evne til å fjerne bærerskap eller infeksjoner med multiresistente Kp. Kp-studiene er finansiert av Trond Mohn Stiftelsen ( https://mohnfoundation.no/amr-prosjekter/) og partnerinstitusjoner.
- Leder for Senter for nye antibakterielle strategier (CANS; https://uit.no/research/cans): Et tverrfaglig forskningssenter finansiert av UiT og Tromsø Forskningsstiftelse (https://tfstiftelse.no/) 2019 -.
- Seksjonsoverlege, Nasjonal kompetansetjeneste for påvisning av antibiotikaresistens (K-res; https://unn.no/fag-og-forskning/k-res) ved Universitetssykehuset Nord-Norge (UNN) finansiert av Helse- og omsorgsdepartementet, Helse Nord RHF og UNN.
Medlem i forskningsgruppe
CV
Utdanning:
1983: Cand.med (MD) Universitetet i Tromsø
1991: Spesialist i Medisinsk mikrobiologi
1994: Dr.med (PhD) Universitetet i Tromsø
2000-01: Visiting Professor Institutt Pasteur, Paris
Yrkespraksis:
1983-95: Turnus-/militærlege. Assistent-/overlege Medisinsk mikrobiologi, Universitetssykehuset i Nord-Norge
1987-90: Stipendiat, Den Norske Kreftforening, v/UiT
1995-96: Avdelingsoverlege Mikrobiologisk avdeling, UNN
1995 - : Førsteamanuensis/Professor Medisinsk mikrobiologi, UiT
1996-00: Nestleder/Leder for studiestyret medisin, UiT
2005-09: Prodekan forskning, Det Medisinske fakultet, UiT
2009 - 17 : Dekan, Det helsevitenskapelige fakultet, UiT
Vedlegg:
- 20-01-16 CV_AS (pdf)