Bilde av Hansen, John Bjarne
Foto: Bjørn-Kåre Iversen
Bilde av Hansen, John Bjarne
Institutt for klinisk medisin john-bjarne.hansen@uit.no +4777625105 41472374

John Bjarne Hansen


Professor

Stillingsbeskrivelse

Forskningsgruppeleder Tromboseforskning (TREC)

Enhetsleder Senter for Tromboseforskning (TREC), Medisinsk klinikk, Universitetssykehuset Nord Norge


  • Carl-Arne Arnesen, Line Holtet Evensen, Kristian Hveem, Maiken Elvestad Gabrielsen, John Bjarne Hansen, Sigrid Kufaas Brækkan :
    Proportion of venous thromboembolism attributed to recognized prothrombotic genotypes in men and women
    Research and Practice in Thrombosis and Haemostasis (RPTH) 2024 DOI
  • Vania Maris Morelli, Omri Snir, Kristian Dalsbø Hindberg, Kristian Hveem, Sigrid Kufaas Brækkan, John Bjarne Hansen :
    High microRNA-145 plasma levels are associated with decreased risk of future incident venous thromboembolism: the HUNT study
    Blood 2024 DOI
  • Paul S. de Vries, Paula Reventun, Michael R. Brown, Adam S. Heath, Jennifer E. Huffman, Ngoc-Quynh Le m.fl.:
    A genetic-association study of circulating coagulation factor VIII and von Willebrand factor levels
    Blood 2024 DOI
  • Eduarda Mazagao Guerreiro, Sergei G. Kruglik, Samantha Swamy, Nadezhda Latysheva, Bjarne Østerud, Jean-Michel Guigner m.fl.:
    Extracellular vesicles from activated platelets possess a phospholipid-rich biomolecular profile and enhance prothrombinase activity
    Journal of Thrombosis and Haemostasis 2024 DOI
  • Birgitte Gladsø Tøndel, Joakim Knutsen Sejrup, Vania Maris Morelli, Maja-Lisa Løchen, Inger Njølstad, Ellisiv B. Mathiesen m.fl.:
    Joint effect of ischemic stroke and obesity on the risk of venous thromboembolism: the Tromsø Study
    Research and Practice in Thrombosis and Haemostasis (RPTH) 2024 DOI
  • Safak Caglayan, John Bjarne Hansen, Omri Snir :
    Optimized workflow to modify microRNA expression in primary human intravascular cells
    BMC Immunology 2023 ARKIV / DOI
  • Espen Waage Skjeflo, Line Holtet Evensen, Søren Beck Jensen, Nadezhda Latysheva, Annika Elisabet Michelsen, Thor Ueland m.fl.:
    Complement factors B, D, C3bBbP and risk of future venous thromboembolism
    Clinical Immunology 2023 ARKIV / DOI
  • Steven P. Grover, Tomohiro Kawano, Jun Wan, Pansakorn Tanratana, Zsofia Polai, Young J. Shim m.fl.:
    C1 inhibitor deficiency enhances contact pathway–mediated activation of coagulation and venous thrombosis
    Blood 2023 ARKIV / DOI
  • Magnus Edvardsen, Ellen-Sofie Hansen, Thor Ueland, Pål Aukrust, Sigrid Kufaas Brækkan, Vania Maris Morelli m.fl.:
    Impact of the von Willebrand factor-ADAMTS-13 axis on the risk of future venous thromboembolism
    Journal of Thrombosis and Haemostasis 2023 ARKIV / DOI
  • Steven P. Grover, Omri Snir, Kristian Dalsbø Hindberg, Tatianna M. Englebert, Sigrid Kufaas Brækkan, Vania Maris Morelli m.fl.:
    High plasma levels of C1-inhibitor are associated with lower risk of future venous thromboembolism
    Journal of Thrombosis and Haemostasis 2023 ARKIV / DOI
  • Monique J.T. Crobach, Rayna J.S. Anijs, Sigrid Kufaas Brækkan, Marianne T. Severinsen, Jens Hammerstrøm, Hanne Skille m.fl.:
    Survival after cancer-related venous thrombosis: the Scandinavian Thrombosis and Cancer Study
    Blood Advances 2023 ARKIV / DOI
  • Dana Meknas, Sigrid Kufaas Brækkan, John Bjarne Hansen, Vania Maris Morelli :
    Surgery As a Trigger for Incident Venous Thromboembolism: Results from a Population-Based Case-Crossover Study
    TH Open 2023 ARKIV / DOI
  • Oda Leknessund, Vania Maris Morelli, John Bjarne Hansen, Sigrid Kufaas Brækkan :
    Hand grip strength in venous thromboembolism: risk of recurrence and mortality
    Research and Practice in Thrombosis and Haemostasis (RPTH) 2023 ARKIV / DOI
  • Sigrid Kufaas Brækkan, John Bjarne Hansen :
    VTE epidemiology and challenges for VTE prevention at the population level: VTE epidemiology
    Thrombosis Update 2023 ARKIV / DOI
  • Samantha Swamy, Thor Ueland, John Bjarne Hansen, Omri Snir, Sigrid Kufaas Brækkan :
    Plasma levels of P-selectin and future risk of incident venous thromboembolism
    Journal of Thrombosis and Haemostasis 2023 ARKIV / DOI
  • Maria A. de Winter, Alicia Uijl, Harry R. Büller, Marc Carrier, Alexander T. Cohen, John Bjarne Hansen m.fl.:
    Redefining clinical venous thromboembolism phenotypes: a novel approach using latent class analysis
    Journal of Thrombosis and Haemostasis 2023 ARKIV / DOI
  • Tobias Frischmuth, Birgitte Gladsø Tøndel, Sigrid Kufaas Brækkan, John Bjarne Hansen, Vania Maris Morelli :
    The Risk of Incident Venous Thromboembolism Attributed to Overweight and Obesity: The Tromso Study
    Thrombosis and Haemostasis 2023 ARKIV / DOI
  • Casper Jan Elis Ullsten-Wahlund, Safak Caglayan, Paulo Czarnewski, John Bjarne Hansen, Omri Snir :
    Sustained and intermittent hypoxia differentially modulate primary monocyte immunothrombotic responses to IL-1β stimulation
    Frontiers in Immunology 2023 ARKIV / DOI
  • Maria A. De Winter, Harry R. Büller, Marc Carrier, Alexander T. Cohen, John Bjarne Hansen, Karin A. H. Kaasjager m.fl.:
    Recurrent venous thromboembolism and bleeding with extended anticoagulation: the VTE-PREDICT risk score
    European Heart Journal 2023 ARKIV / DOI
  • Vårin Eiriksdatter Wikan, Birgitte Gladsø Tøndel, Vania Maris Morelli, Ellen Elisabeth Brodin, Sigrid Kufaas Brækkan, John Bjarne Hansen :
    Diagnostic Blood Biomarkers for Acute Pulmonary Embolism: A Systematic Review
    Diagnostics (Basel) 2023 ARKIV / DOI
  • Fridtjof Balteskard Rinde, Camilla Tøvik Jørgensen, Heidi Hassel Pettersen, John Bjarne Hansen, Waleed Ghanima, Sigrid Kufaas Brækkan :
    Low D-dimer levels at diagnosis of venous thromboembolism are associated with reduced risk of recurrence: data from the TROLL registry
    Journal of Thrombosis and Haemostasis 2023 ARKIV / DOI
  • Ellen-Sofie Hansen, Magnus Edvardsen, Pål Aukrust, Thor Ueland, John Bjarne Hansen, Sigrid Kufaas Brækkan m.fl.:
    Combined effect of high factor VIII levels and high mean platelet volume on the risk of future incident venous thromboembolism
    Journal of Thrombosis and Haemostasis 2023 ARKIV / DOI
  • Scott C. Woller, Kerstin de Wit, Helia Robert-Ebadi, Camila Masias, Frederikus A. Klok, Paul L. den Exter m.fl.:
    A systematic review of biomarkers among hospitalized patients with COVID-19 predictive of venous thromboembolism: A communication from the Predictive and Diagnostic Variables Scientific and Standardization Committee of the ISTH
    Research and Practice in Thrombosis and Haemostasis (RPTH) 2022 ARKIV / DOI
  • Florian Thibord, Derek Klarin, Jennifer A. Brody, Ming-Huei Chen, Michael G. Levin, Daniel I. Chasman m.fl.:
    Cross-Ancestry Investigation of Venous Thromboembolism Genomic Predictors
    Circulation 2022 ARKIV / DOI
  • Elias Allarai, Wei-Hsuan Lee, Stephen Burgess, Susanna C. Larsson, Sara Lindstrom, Lu Wang m.fl.:
    Genetically predicted cortisol levels and risk of venous thromboembolism
    PLOS ONE 2022 ARKIV / DOI
  • Line Holtet Evensen, Carl-Arne Arnesen, Frits Richard Rosendaal, Maiken Elvestad Gabrielsen, Ben Michael Brumpton, Kristian Hveem m.fl.:
    The Risk of Venous Thromboembolism Attributed to Established Prothrombotic Genotypes
    Thrombosis and Haemostasis 2022 ARKIV / DOI
  • Lisa Jakobsen, Tobias Frischmuth, Sigrid Kufaas Brækkan, John Bjarne Hansen, Vania Maris Morelli :
    Joint Effect of Multiple Prothrombotic Genotypes and Mean Platelet Volume on the Risk of Incident Venous Thromboembolism
    Thrombosis and Haemostasis 2022 ARKIV / DOI
  • Oda Leknessund, Vania Maris Morelli, Bjørn Heine Strand, John Bjarne Hansen, Sigrid Kufaas Brækkan :
    Hand grip strength and risk of incident venous thromboembolism: The Tromsø study
    Research and Practice in Thrombosis and Haemostasis (RPTH) 2022 FULLTEKST / ARKIV / DOI
  • Christabel Esi Damoah, Omri Snir, Kristian Dalsbø Hindberg, Peter Garred, Judith K Ludviksen, Sigrid Kufaas Brækkan m.fl.:
    High Levels of Complement Activating Enzyme MASP-2 Are Associated With the Risk of Future Incident Venous Thromboembolism
    Arteriosclerosis, Thrombosis and Vascular Biology 2022 ARKIV / DOI
  • Paul L. den Exter, Scott C. Woller, Helia Robert-Ebadi, Camila Masias, Pierre-Emmanuel Morange, David Castelli m.fl.:
    Management of bleeding risk in patients who receive anticoagulant therapy for venous thromboembolism: Communication from the ISTH SSC Subcommittee on Predictive and Diagnostic Variables in Thrombotic Disease
    Journal of Thrombosis and Haemostasis 2022 ARKIV / DOI
  • Carolina E. Touw, Banne Nemeth, Willem M. Lijfering, Raymond A. van Adrichem, line Wilsgård, Nadezhda Latysheva m.fl.:
    Effect of lower-leg trauma and knee arthroscopy on procoagulant phospholipid-dependent activity
    Research and Practice in Thrombosis and Haemostasis (RPTH) 2022 ARKIV / DOI
  • Omri Snir, line Wilsgård, Nadezhda Latysheva, Casper Ullsten-Wahlund, Sigrid Kufaas Brækkan, Kristian Dalsbø Hindberg m.fl.:
    Plasma levels of platelet-derived microvesicles are associated with risk of future venous thromboembolism
    Journal of Thrombosis and Haemostasis 2022 ARKIV / DOI
  • Helle Jørgensen, Erzsebet Horvath-Puho, Kristina Laugesen, Sigrid Kufaas Brækkan, John Bjarne Hansen, Henrik Toft Sørensen :
    Venous thromboembolism and risk of depression: a population-based cohort study
    Journal of Thrombosis and Haemostasis 2022 ARKIV / DOI
  • Aniket Mishra, Rainer Malik, Tsuyoshi Hachiya, Tuuli Jürgenson, Shinichi Namba, Daniel C. Posner m.fl.:
    Stroke genetics informs drug discovery and risk prediction across ancestries
    Nature 2022 ARKIV / DOI
  • Tobias Frischmuth, Kristian Hindberg, Pål Aukrust, Thor Ueland, Sigrid Kufaas Brækkan, John Bjarne Hansen m.fl.:
    Elevated plasma levels of plasminogen activator inhibitor-1 are associated with risk of future incident venous thromboembolism
    Journal of Thrombosis and Haemostasis 2022 ARKIV / DOI
  • Helle Jørgensen, Erzsébet Horváth-Puhó, Kristina Laugesen, Sigrid Kufaas Brækkan, John Bjarne Hansen, Henrik Toft Sørensen :
    The Interaction Between Venous Thromboembolism and Socioeconomic Status on the Risk of Disability Pension
    Clinical Epidemiology 2022 ARKIV / DOI
  • Birgitte Gladsø Tøndel, Vania Maris Morelli, John Bjarne Hansen, Sigrid Kufaas Brækkan :
    Risk factors and predictors for venous thromboembolism in people with ischemic stroke: A systematic review
    Journal of Thrombosis and Haemostasis 11. juli 2022 ARKIV / DOI
  • Joakim Knutsen Sejrup, Birgitte Gladsø Tøndel, Vania Maris Morelli, Maja-Lisa Løchen, Inger Njølstad, Ellisiv B. Mathiesen m.fl.:
    Joint effect of myocardial infarction and obesity on the risk of venous thromboembolism: The Tromsø Study
    Journal of Thrombosis and Haemostasis 2022 ARKIV / DOI
  • Helle Jørgensen, Erzsebet Horvath-Puho, Kristina Laugesen, Sigrid Kufaas Brækkan, John Bjarne Hansen, Henrik Toft Sørensen :
    Socioeconomic status and risk of incident venous thromboembolism
    Journal of Thrombosis and Haemostasis 2021 DOI
  • Gro Grimnes, Soerajja Bhoelan, Kristian Hindberg, Mark Davids, Max Nieuwdorp, Tom E. Mollnes m.fl.:
    Impact of a Vancomycin-Induced Shift of the Gut Microbiome in a Gram-Negative Direction on Plasma Factor VIII:C Levels: Results from a Randomized Controlled Trial
    Thrombosis and Haemostasis 2021 ARKIV / DOI
  • Helle Jørgensen, Erzsébet Horváth-Puhó, Kristina Laugesen, Sigrid Kufaas Brækkan, John-Bjarne Hansen, Henrik Toft Sørensen :
    Risk of a permanent work-related disability pension after incident venous thromboembolism in Denmark: A population-based cohort study
    PLoS Medicine 2021 ARKIV / DOI
  • Line Holtet Evensen, Aaron R. Folsom, James S. Pankow, John-Bjarne Hansen, Matthew Allison, Mary Cushman m.fl.:
    Hemostatic factors, inflammatory markers, and risk of incident venous thromboembolism: The Multi-Ethnic Study of Atherosclerosis
    Journal of Thrombosis and Haemostasis 2021 ARKIV / DOI
  • Hanne Skille, Benedikte Paulsen, Kristian Hveem, Marianne T. Severinsen, Maiken Elvestad Gabrielsen, Søren R. Kristensen m.fl.:
    Prothrombotic genotypes and risk of venous thromboembolism in occult cancer
    Thrombosis Research 2021 ARKIV / DOI
  • Grégoire Le Gal, Marc Carrier, Lana A. Castellucci, Adam Cuker, John-Bjarne Hansen, Frederikus A. Klok m.fl.:
    Development and implementation of common data elements for venous thromboembolism research: on behalf of SSC Subcommittee on official Communication from the SSC of the ISTH
    Journal of Thrombosis and Haemostasis 2021 DOI
  • Magnus Edvardsen, Kristian Hindberg, Ellen-Sofie Hansen, Vania Maris Morelli, Thor Ueland, Pål Aukrust m.fl.:
    Plasma levels of von Willebrand factor and future risk of incident venous thromboembolism
    Blood Advances 2021 ARKIV / DOI
  • Ellen-Sofie Hansen, Magnus Edvardsen, Pål Aukrust, Thor Ueland, John Bjarne Hansen, Sigrid Kufaas Brækkan m.fl.:
    Galectin-3-binding protein and future venous thromboembolism
    Research and Practice in Thrombosis and Haemostasis (RPTH) 2024 DOI
  • Bjarne Østerud, Nadezhda Latysheva, John Bjarne Hansen, Omri Snir :
    “A rapid, sensitive, and specific assay to measure tissue factor activity based on chromogenic determination of thrombin generation”: reply
    Journal of Thrombosis and Haemostasis 2023 DOI
  • Steven P. Grover, Sigrid Kufaas Brækkan, Nigel Mackman, John Bjarne Hansen :
    “High plasma levels of C1-inhibitor are associated with lower risk of future venous thromboembolism”: reply
    Journal of Thrombosis and Haemostasis 2023 DOI
  • Steven P. Grover, Linda Sundler Björkman, Sigrid Kufaas Brækkan, Bengt Zöller, John Bjarne Hansen, Nigel Mackman :
    “C1-inhibitor levels and Venous Thromboembolism: Results from a Mendelian Randomization Study”: comment from Grover et al
    Journal of Thrombosis and Haemostasis 2023 DOI
  • Casper Ullsten-Wahlund, Safak Caglayan, Christabel Esi Damoah, John Bjarne Hansen, Omri Snir :
    Hypoxia augments proinflammatory activation of endothelial cells towards a prothrombotic phenotype
    2021

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    Forskningsinteresser

    Kliniske epidemiologi og risikofaktorer for venøs tromboembolisme

    Diagnostiske og prediktive biomarkører for venøs tromboembolisme

    Patofysiologi ved venøs tromboembolisme

     

    Undervisning

    2010-2023: Delemneleder i delemne om hematology, immunologi, og infeksjonssykdommer for                                           medisinstudenter ved UiT

    2010-2023: Medlem i eksamenskommisjonen for tredje års eksamen for medisinstudenter ved UiT

     




    CV

    Utdanning

    1989: Cand.med (MD), Universitetet i Tromsø

    1997: Dr. med (PhD i kardiovaskulær medisin) Universitetet i Tromsø

    Tidligere akademiske stillinger

    1991-1994: Doktorgradsstudent ved Universitetet i Tromsø 

    1994-1995: Postdoktor ved Universitetet i Tromsø

    1996-2005: Førsteamanuensis i medisin, Universitetet i Tromsø (20-50% stilling)

    2005-2008: Professor I i Indremedisin/Hematologi, Universitetet i Tromsø  (100% stilling)

    2007-2008: Prodekan forskning, Det helsevitenskapelige fakultet, Universitetet i Tromsø

    2008-2009: Visiting professor, The Scripps Research Institute, La Jolla, CA, USA

     

    ,

    Publikasjoner

    >300 originale artikler i fagfellevurderte tidsskrift registret i Pubmed, 28 oversiktsartikler, og 12 bokkapitler. Bidratt til >370 abstract presentert ved og pulibsert i forbindelse med internasjonale vitenskapelige konferanser. 

     

    Veiledning av PhD-studenter og postdoktorer

    Fullførte doktorgrader  : Hovedveileder: 35; Biveileder: 5

    Pågående doktorgrader: Hovedveileder for 7 og biveileder for 6

    Mentor for 13 tidligere postdoktorer og 3 nåværende postdoktorer