Ruth H Paulssen

Professor Institutt for klinisk medisin
Flag icon Flag icon

Name:                        Ruth Hracky Paulssen

Date of Birth:            30.08.57

Nationality:            German

Marital status:          Married, two children

Education

1986:               Diploma in Biochemistry at University of Hannover, Germany. Diploma work at the Botanical Institute, Ludwig-Maximillians University Munich, Germany. Title: «Phosphorylation/Dephosphorylation in the Cytosolof Pea Mesophyll cells».

1992:               Ph.D., University of Oslo. Thesis title: «G protein-coupled Transmembrane Signalling in Prolactin-Producing rat Pituitary Tumour Cells».

 Appointments

1981 – 1984:   Research Assistant at the Institute of Clinical Chemistry, Veterinary University Hannover, Germany.

1985 – 1987:   Student Fellow, Botanical Institute, Ludwig-Maximillians University Munich, Germany.

1986:             Research Assistant, Botanical Institute, Ludwig-Maximillians University Munich, Germany.

1988:             Bioengineer, Institute of Medical Biochemistry, University of Oslo, Norway.

1989-1993:     Ph.D. Student (The Norwegian Cancer Society Fellowship), Institute of Medical Biochemistry, University of Oslo, Norway.

1993-1995:     Post doctoral Fellow (The Human Frontier Science Program Organization, HFSPO Long-term Fellowship), Department of Pharmacology, University of Texas Southwestern Medical Center at Dallas, USA.

1996-1998:     Research Scientist, Institute of Clinical Medicine, University of Tromsø, Norway.

1999-2004      Associate professor, Institute of Clinical Medicine, Laboratory of Molecular Medical Research, University of Tromsø and University Hospital of North Norway (UNN), Tromsø, Norway.

Since 2005      Professor, Department of Clinical Medicine, Laboratory of Molecular Medical Research, University of Tromsø, Tromsø, Norway.

Since 2008      Additional 20% engagement at UNN (Head of  MRCT faciltiy).

Professor i molekylær biologi og genteknologi

Leder for Genomics Support Center Tromsø (GSCT)

  • Gundersen, Mona Dixon; Goll, Rasmus; Fenton, Christopher Graham; Anderssen, Endre; Sørbye, Sveinung Wergeland; Florholmen, Jon; Paulssen, Ruth H. Fibrosis Mediators in the Colonic Mucosa of Acute and Healed Ulcerative Colitis. Clinical and Translational Gastroenterology 2019; Volum 10 (10). ISSN 2155-384X.s e00082 - .s doi: 10.14309/ctg.0000000000000082.

  • Taman, Hagar Mohamed; Fenton, Christopher Graham; Hensel, Inga Viktoria; Anderssen, Endre; Florholmen, Jon; Paulssen, Ruth H. Transcriptomic Landscape of Treatment-Naïve Ulcerative Colitis. Journal of Crohn's and colitis 2018; Volum 12 (3). ISSN 1873-9946.s 327 - 336.s doi: 10.1093/ecco-jcc/jjx139.

  • Taman, Hagar; Fenton, Christopher Graham; Hensel, Inga Viktoria; Anderssen, Endre; Florholmen, Jon; Paulssen, Ruth H. Genome-Wide DNA Methylation in Treatment-Naïve Ulcerative Colitis. Journal - Crohn's and Colitis Foundation of Canada 2018; Volum 12 (11). ISSN 1197-4982.s 1338 - 1347.s doi: 10.1093/ecco-jcc/jjy117.

  • Pasing, Yvonne; Fenton, Christopher Graham; Jorde, Rolf; Paulssen, Ruth H. Changes in the human transcriptome upon vitamin D supplementation. Journal of Steroid Biochemistry and Molecular Biology 2017; Volum 173. ISSN 0960-0760.s 93 - 99.s doi: 10.1016/j.jsbmb.2017.03.016.

  • Schniers, Armin; Anderssen, Endre; Fenton, Christopher Graham; Goll, Rasmus; Pasing, Yvonne; Paulssen, Ruth H; Florholmen, Jon; Hansen, Terkel. The Proteome of Ulcerative Colitis in Colon Biopsies from Adults - Optimized Sample Preparation and Comparison with Healthy Controls. PROTEOMICS - Clinical Applications 2017; Volum 11 (11-12). ISSN 1862-8346.s doi: 10.1002/prca.201700053.

  • Florholmen-Kjær, Åse; Goll, Rasmus; Fuskevåg, Ole-Martin; Nygård, Ingvild; Paulssen, Ruth H; Revhaug, Arthur; Mortensen, Kim Erlend. The impact of partial hepatectomy on oxidative state in the liver remnant - An in vivo swine model. Redox Biology 2016; Volum 9. ISSN 2213-2317.s 15 - 21.s doi: 10.1016/j.redox.2016.05.005.

  • Lønvik, Kenneth; Sørbye, Sveinung Wergeland; Nilsen, Marit Nina; Paulssen, Ruth H. Prognostic value of the MicroRNA regulators Dicer and Drosha in non-small-cell lung cancer: Co-expression of Drosha and miR-126 predicts poor survival. (fulltekst) BMC Clinical Pathology 2015; Volum 14 (45). ISSN 1472-6890.s doi: 10.1186/1472-6890-14-45.

  • Martinez, Inigo Zubiavrre; Fenton, Christopher Graham; Taman, Hagar Mohamed; Pettersen, ingvild; Hellevik, Turid; Paulssen, Ruth H. Tumorigenic responses of Cancer-Associated Fibroblasts after ablative radiotherapy: A transcriptome-profiling study. Journal of Cancer Therapy 2013; Volum 4 (1). ISSN 2151-1934.s 208 - 250.s doi: 10.4236/jct.2013.41031.

  • Olsen, Karina Standahl; Fenton, Christopher Graham; Frøyland, Livar; Waaseth, Marit; Paulssen, Ruth H; Lund, Eiliv. Plasma Fatty Acid Ratios Affect Blood Gene Expression Profiles - A Cross-Sectional Study of the Norwegian Women and Cancer Post-Genome Cohort. PLOS ONE 2013; Volum 8 (6). ISSN 1932-6203.s doi: 10.1371/journal.pone.0067270.

  • Sitras, Vasilis; Fenton, Christopher Graham; Paulssen, Ruth H; Vårtun, Åse; Acharya, Ganesh. Differences in Gene Expression between First and Third Trimester Human Placenta: A Microarray Study. PLOS ONE 2012; Volum 7 (3). ISSN 1932-6203.s doi: 10.1371/journal.pone.0033294.

  • Hellevik, Turid; Pettersen, ingvild; Berg, Vivian; Winberg, Jan-Olof; Moe, Bjørn Torvald Greve; Bartnes, Kristian; Paulssen, Ruth H; Busund, Lill-Tove; Bremnes, Roy M.; Chalmers, Antony; Martinez, Inigo Zubiavrre. Cancer-associated fibroblasts from human NSCLC survive ablative doses of radiation but their invasive capacity is reduced. Radiation Oncology 2012; Volum 7. ISSN 1748-717X.s doi: 10.1186/1748-717X-7-59.

  • Dumeaux, vanessa; Olsen, Karina Standahl; Nuel, G; Paulssen, Ruth H; Børresen-Dale, Anne-Lise; Lund, Eiliv. Deciphering Normal Blood Gene Expression Variation-The NOWAC Postgenome Study. PLoS Genetics 2010; Volum 6 (3). ISSN 1553-7390.s doi: 10.1371/journal.pgen.1000873.

  • Pedersen, hege lynum; Hjerde, erik; Paulsen, steinar; Hansen, Hilde; Olsen, Lotte; Thode, Sunniva Katharina; Dos Santos, Marcos Tadeu; Paulssen, Ruth H; Willassen, Nils P; Haugen, Peik. Global responses of Aliivibrio salmonicida to hydrogen peroxide as revealed by microarray analysis. Marine Genomics 2010; Volum 3. ISSN 1874-7787.s 193 - 200.s doi: 10.1016/j.margen.2010.10.002.

  • Snipstad, Kristin; Fenton, Christopher Graham; Kjæve, Jørn; Cui, Guanglin; Anderssen, Endre; Paulssen, Ruth H. New specific molecular targets for radio-chemotherapy of rectal cancer. Molecular Oncology 2010; Volum 4 (1). ISSN 1574-7891.s 52 - 64.s doi: 10.1016/j.molonc.2009.11.002.

  • Sitras, Vasilis; Paulssen, Ruth H; Leirvik, Jørn; VÅrtun, Åse; Acharya, Ganesh. Placental Gene Expression Profile in Intrauterine Growth Restriction Due to Placental Insufficiency. Reproductive Sciences 2009; Volum 16 (7). ISSN 1933-7191.s 701 - 711.s doi: 10.1177/1933719109334256.

  • Sitras, Vasilis; Paulssen, Ruth H; Grønaas, Halvor; Leirvik, Jørn; Hanssen, Tor-Arne; VÅrtun, Åse; Acharya, Ganesh. Differential Placental Gene Expression in Severe Preeclampsia. Placenta 2009; Volum 30 (5). ISSN 0143-4004.s 424 - 433.s doi: 10.1016/j.placenta.2009.01.012.

  • Ørbo, Anne; Moe, Bjørn Torvald Greve; Grønaas, Halvor; Paulssen, Ruth H. Early effects of high concentrations of progesterone and Mifepristone. A gene expression study of endometrial cancer cells (ishikawa). Journal of Steroid Biochemistry and Molecular Biology 2009; Volum 113 (1-2). ISSN 0960-0760.s 139 - 149.s doi: 10.1016/j.jsbmb.2008.12.003.

  • Paulssen, Ruth H; Moe, Bjørn; Grønaas, Halvor; Ørbo, Anne. Gene expression in endometrial cancer cells (Ishikawa) after short time high dose exposure to progesterone. Steroids 2008; Volum 73. ISSN 0039-128X.s 116 - 128.s doi: 10.1016/j.steroids.2007.09.010.

  • Sitras, Vasilis; Paulssen, Ruth H; Grønaas, Halvor; VÅrtun, Åse; Acharya, Ganesh. Gene expression profile in labouring and non-labouring human placenta near term. Molecular human reproduction 2008; Volum 14. ISSN 1360-9947.s 61 - 65.s doi: 10.1093/molehr/gam083.

  • Paulssen, Ruth H; Moe, Bjørn; Grønaas, Halvor; Ørbo, Anne. Gene expression in endometrial cancer cells (Ishikawa)after short time high exposure to progesterone. Steroids 2008; Volum 73 (1). ISSN 0039-128X.s 116 - 128.s doi: 10.1016/j.steroids.2007.09.010.

  • Paulssen, Ruth H; Olsen, Lotte; Sogn, Thea Charlotte. MagNa Pure Compact RNA Isolation Kit: Isolation of High-Quality Total RNA from a Broad Range of Sample Material. Biochemica 2006; Volum 2. ISSN 0946-1310.s 14 - 16.

  • Fraeyman, N.; Van Emmelo, J.; Paulssen, Ruth H; Vermis, K.. Desensitization of muscarinic receptors. Receptors and Channels 2004; Volum 10. ISSN 1060-6823.s 1 - 10.s doi: 10.1080/10606820490281175.

  • Brodin, E; Svensson, Birgit; Paulssen, Ruth H; Nordøy, Arne; Hansen, John Bjarne. Intravascular release and urinary excretion of tissue factor pathway inhibitor during heparin treatment. Journal of Laboratory and Clinical Medicine 2004; Volum 144 (5). ISSN 0022-2143.s 246 - 253.

  • Ilkaeva, Olga; Kinch, Lisa; Paulssen, Ruth H; Ross, Elliott. Mutations of the carboxyl terminal domain of phospholipase C-beta 1 delineate the dimer interface and a potential Galphaq interaction site. Journal of Biological Chemistry 2002; Volum 277. ISSN 0021-9258.s 4294 - 4300.

  • Thommesen, Liv; Hofsli, Eva; Paulssen, Ruth H; Anthonsen, Marit; Lærgreid, Astrid. Molecular Mechanisms involved in gastrin mediated regulation of cAMP-responsive (CRE) promotor element. American Journal of Physiology 2001; Volum 281. ISSN 0002-9513.s E1316 - E1325.

  • Johansen, Per Wiik; Paulssen, Ruth H; Bjøro, Trine; Gautvik, Kaare M; Gordeladze, Jan Oxholm. Distinct guanine nucleotide binding protein alpha-subunit receptor coupling in GH cell lines: effects of bromocriptine and hormones on effector enzyme modulation. Cellular Physiology and Biochemistry 2001; Volum 11 (6). ISSN 1015-8987.s 339 - 352.

  • Johansen, Per Wiik; Paulssen, Ruth H; Bjøro, Trine; Gautvik, Kaare; Gordeladze, Jan. Distinct guanine nucleotide binding protein alpha-subunit receptor coupling in GH cell lines: Effects of bromocriptine and hormnones on effector enzyme modulation. Cellular Physiology and Biochemistry 2001; Volum 11. ISSN 1015-8987.s 339 - 352.

  • Paulssen, Ruth H; Fraeyman, Norbert; Florholmen, Jon. Activation of phospholipase C by CCK receptor subtypes with different G protein-coupling specificities in hormone secreting pancreatic cell lines. Biochemical Pharmacology 2000; Volum 60. ISSN 0006-2952.s 865 - 875.

  • Gordeladze, Jan Oxholm; Haugen, T. B.; Paulssen, E. J.; Paulssen, R. H.. Phospholipase C activation in rat pituitary adenoma (GH) cells. Bioscience Reports 1996; Volum 16. ISSN 0144-8463.s 65 - 74.

  • Gordeladze, Jan Oxholm; Haugen, Trine B.; Paulssen, Eyvind Jakob; Paulssen, Ruth H. Phospholipase C activation in rat pituitary adenoma (GH) cells.. Bioscience Reports 1996; Volum 16 (1). ISSN 0144-8463.s 65 - 74.

  • Mortensen, Berit Marie; Lund, Hanne Wessel; Jablonski, Greg; Paulssen, Ruth H; Gordeladze, Jan Oxholm. Direct effects of vitamin D3 analogues on G-protein mediated signalling systems in rat osteosarcoma cells and rat pituitary adenoma cells. Bioscience Reports 1995; Volum 15 (3). ISSN 0144-8463.s 135 - 50.

  • Gordeladze, Jan Oxholm; Johansen, Per Wiik; Paulssen, Ruth H; Paulssen, Eyvind J; Gautvik, Kaare M. G-proteins: implications for pathophysiology and disease. European Journal of Endocrinology 1994; Volum 131 (6). ISSN 0804-4643.s 557 - 574.

  • Paulssen, Ruth H; Johansen, Per Wiik; Gordeladze, Jan Oxholm; Nymoen, Ole-Martin; Paulssen, Eyvind Jakob; Gautvik, Kaare M. Cell-specific expression and function of adenylyl cyclases in rat pitruitary tumour cell lines. European Journal of Biochemistry (EJB) 1994; Volum 222 (1). ISSN 0014-2956.s 97 - 103.

  • Haugen, Trine B.; Paulssen, Ruth H; Hansson, Vidar. Cell-specific expression of Gq/11 protein and mRNA in rat seminiferous tubules.. FEBS Letters 1993; Volum 329 (1-2). ISSN 0014-5793.s 96 - 98.

  • Paulssen, Ruth H; Paulssen, Eyvind Jakob; Gautvik, Kaare M; Gordeladze, Jan Oxholm. Modulation of G proteins and second messenger responsiveness by steroid hormones in GH3 rat pituitary tumour cells. Acta Physiologica Scandinavica 1992; Volum 146 (2). ISSN 0001-6772.s 511 - 518.

  • Paulssen, Eyvind Jakob; Paulssen, Ruth H; Gautvik, Kaare M; Gordeladze, Jan Oxholm. "Cross-talk" between phospholipase C and adenylyl cyclase involves regulation of G-protein levels in GH3 rat pituitary cells. Cellular Signalling 1992; Volum 4 (6). ISSN 0898-6568.s 747 - 755.

  • Paulssen, Eyvind Jakob; Paulssen, Ruth H; Gautvik, Kaare M; Gordeladze, Jan Oxholm. Hypothalamic hormones modulate G protein levels and second messenger responsiveness in GH3 rat pituitary tumour cells. Biochemical Pharmacology 1992; Volum 44 (3). ISSN 0006-2952.s 471 - 477.

  • Paulssen, Ruth H; Paulssen, Eyvind Jakob; Gautvik, Kaare M; Gordeladze, Jan Oxholm. The thyroliberin receptor interacts directly with a stimulatory guanine-nucleotide-binding protein in the activation of adenylyl cyclase in GH3 rat pituitary tumour cells. Evidence obtained by use of antisense RNA inhibition and immunoblocking of the stimulatory guanine-nucleotide-binding protein. European Journal of Biochemistry (EJB) 1992; Volum 204 (1). ISSN 0014-2956.s 413 - 418.

  • Paulssen, Ruth H; Paulssen, Eyvind Jakob; Gordeladze, Jan Oxholm; Hansson, Vidar; Haugen, Trine B.. Cell-specific expression of guanine nucleotide-binding proteins in rat testicular cells. Biology of Reproduction 1991; Volum 45 (4). ISSN 0006-3363.s 566 - 571.

  • Paulssen, Eyvind Jakob; Paulssen, Ruth H; Haugen, Trine B.; Gautvik, Kaare M; Gordeladze, Jan Oxholm. Regulation of G protein mRNA levels by thyroliberin, vasoactive intestinal peptide and somatostatin in prolactin-producing rat pituitary adenoma cells. Acta Physiologica Scandinavica 1991; Volum 143 (2). ISSN 0001-6772.s 195 - 201.

  • Paulssen, Eyvind Jakob; Paulssen, Ruth H; Haugen, Trine B.; Gautvik, Kaare M; Gordeladze, Jan Oxholm. Cell specific distribution of guanine nucleotide-binding regulatory proteins in rat pituitary tumour cell lines. Molecular and Cellular Endocrinology 1991; Volum 76 (1-3). ISSN 0303-7207.s 45 - 53.

  • Paulssen, Ruth H; Paulssen, Eyvind Jakob; Alestrøm, Peter; Gordeladze, Jan Oxholm; Gautvik, Kaare M. Specific antisense RNA inhibition of growth hormone production in differentiated rat pituitary tumour cells. Biochemical and Biophysical Research Communications - BBRC 1990; Volum 171 (1). ISSN 0006-291X.s 293 - 300.

  • Fenton, Christopher Graham; Taman, Hagar; Florholmen, Jon; Paulssen, Ruth H. Transcriptional profiling of ulcerative colitis in remission. Journal of Crohn's and colitis 2019; Volum 13. ISSN 1873-9946.s S113 - S114.s doi: 10.1093/ecco-jcc/jjy222.179.

  • Fenton, Christopher Graham; Taman, Hagar; Florholmen, Jon; Paulssen, Ruth H. Transcriptional profiling of ulcerative colitis in remission. 14th Congress of ECCO 2019-03-06 - 2019-03-09 2019.

  • Paulssen, Ruth H; Taman, Hagar Mohamed; Fenton, Christopher Graham; Hensel, Inga Viktoria; Anderssen, Endre; Florholmen, Jon. Novel regulatory DNA methylation features of relevance for ulcerative colitis. American Journal of Gastroenterology 2018; Volum 113. ISSN 0002-9270.s doi: 10.1038/ajg2017.452.

  • Paulssen, Ruth H; Taman, Hagar Mohamed; Fenton, Christopher Graham; Hensel, Inga Viktoria; Anderssen, Endre; Florholmen, Jon. Novel regulatory DNA methylation features of relevance for ulcerative colitis. Advances in Inflammatory Bowel Diseases 2017-11-09 - 2017-11-11 2017.

  • Gundersen, Mona Dixon; Goll, Rasmus; Florholmen, Jon; Paulssen, Ruth H. Mucosal healing in active ulcerative colitis treated with infliximab to disease remission. Inflammatory Bowel Diseases 2016; Volum 22. ISSN 1078-0998.s S63 - S64.

  • Paulssen, Ruth H; Goll, Rasmus; Florholmen, Jon. PROFILE: As inflammatory bowel disease grows in global incidence, Dr Jon Florholmen outlines what could help to create a cure. PAN european networks science and technology 2014.

  • Sitras, Vasilis; Fenton, Christopher Graham; Paulssen, Ruth H; VÅrtun, Åse; Acharya, Ganesh. Global gene expression profiling in the first and third trimesters of normal human pregnancy. Placenta 2011; Volum 32 (9). ISSN 0143-4004.s A136 - .

  • Sitras, Vasilis; Fenton, Christopher Graham; Paulssen, Ruth H; VÅrtun, Åse; Acharya, Ganesh. GLOBAL PLACENTAL GENE EXPRESSION PROFILING IN THE FIRST AND THIRD TRIMESTERS OF NORMAL HUMAN PREGNANCY. Placenta 2011; Volum 32 (9). ISSN 0143-4004.s A136 - A136.

  • Hellevik, Turid; Pettersen, Inger; Winberg, Jan-Olof; Berg, Vivian; Paulssen, Ruth H; Bartnes, Kristian; Busund, Lill-Tove; Bremnes, Roy M.; Martinez, Inigo Zubiavrre. The Impact of Ionizing Radiation on the Motility and Matrix Remodelling Properties of Carcinoma-associated Fibroblasts. European Journal of Cancer 2011; Volum 47. ISSN 0959-8049.s S142 - S143.

  • Lund, trine; Hals, Margareth Bergesen; Paulssen, Ruth H; Ytrehus, Kirsti. Increased gene expression diversity between female and male mice hearts after transverse aortic constriction (TAC). Regional forskningskonferanse innen medisin og helse 2009-03-25 - 2009-03-26 2009.

  • Snipstad, Kristin; Fenton, Christopher Graham; Kjaeve, J; Kjæve, Jørn; Anderssen, Endre; Paulssen, Ruth H. New specific molecular targets for radiochemotherapy in colorectal cancer. The FEBS Journal 2009; Volum 276. ISSN 1742-464X.s 121 - 121.

  • Olsen, Karina Standahl; Fenton, CG; Anderssen, Endre; Frøyland, Livar; Paulssen, RH; Lund, E. Associations between serum linolenic acid/alpha-linolenic acid ratio and blood gene expression profiles. The FEBS Journal 2009; Volum 276. ISSN 1742-464X.s 115 - 116.

  • Lund, trine; Hals, Margareth Bergesen; Paulssen, Ruth H; Ytrehus, Kirsti. Increased gene expression diversity between female and male hearts after transverse aortic constriction (TAC). European Journal of Heart Failure. Supplements 2009; Volum 8 (2). ISSN 1567-4215.

  • Lund, trine; Hals, Margareth Bergesen; Paulssen, Ruth H; Ytrehus, Kirsti. Increased gene expression diversity between female and male hearts after transverse aortic constriction (TAC). Heart Failure 2009-05-30 - 2009-06-02 2009.

  • Sitras, Vasilis; Paulssen, Ruth H; Grønaas, HS; Leirvik, Jørn; VÅrtun, Åse; Acharya, Ganesh. Differential Placental Gene Expression in Severe Preeclampsia. Gynekologen 2008; Volum 21 (3). ISSN 0805-2158.s 39 - .

  • Sitras, Vasilis; Paulssen, Ruth H; Grønaas, Halvor; VÅrtun, Åse; Acharya, Ganesh. Placental Gene Expression in Severe Preeclampsia. (Abstracts of the 20th European Congress of Obstetrics and Gynaecology). Acta Obstetrica Ginecologica Portuguesa 2008. ISSN 1646-5830.s 51 - 52.

  • Dumeaux, vanessa; Olsen, Karina Standahl; Leirvik, Jørn; Paulssen, Ruth H; Borresen-Dale, AL; Lund, Eiliv. Variation of gene expression profiles in whole blood from a large representative sample of postmenopausal Norwegian women. European Journal of Cancer 2008; Volum 6. ISSN 0959-8049.s 97 - 97.

  • Sitras, Vasilis; Paulssen, Ruth H; Grønaas, Halvor; Ganesh, Acharya. Gene expression profile in labouring and non-labouring placenta near term. American Journal of Obstetrics and Gynecology 2007; Volum 195. ISSN 0002-9378.

  • Paulssen, Ruth H; Moe, Bjørn; Grønaas, Halvor; Ørbo, Anne. Gene expression in endometrial cancer cells (ishikawa) after short time high dose exposure to progestins. Virchows Archiv 2007; Volum 451. ISSN 0945-6317.s 163 - 164.

  • Mortensen, Elin; Hansen, L; Bjurstam, Nils; Klenow, S; Frantzen, Jan-Ole; Paulssen, Ruth H. Imprint of core biopsies as a reliable diagnostic tool in breast cancer and possible usefullness for research purposes. Breast Cancer Research 2005; Volum 7. ISSN 1465-5411.s 33 - .

  • Paulssen, Ruth H; Sørli, Jorid; Evgenov, Natalia Victorovna; Krum-Hansen, Sanda. Regulation and expression of protein kinase C isoforms by cholecystokinin and gastrin in a somatostatin-secreting pancreatic Rin1027-B2 cell line. European Journal of Biochemistry (EJB) 2001; Volum 268. ISSN 0014-2956.s 103 - .

  • Fraeyman, Norbert; Paulssen, Ruth H. Central role of PKC-alpha in the desensitisation of M3-muscarinic receptors. European Journal of Biochemistry (EJB) 2001; Volum 268. ISSN 0014-2956.s 92 - .

  • Evgenov, Natalia Victorovna; Paulssen, Ruth H; Evgenov, OV; Christiansen, Ingrid B; Florholmen, Jon. Tunor necrosis factor-alpha induces apoptosis in an insulin-secreting beta-cell line. Diabetes Research and Clinical Practice 2000; Volum 50. ISSN 0168-8227.

  • Hansen, J.-B.; Svensson, Birgit; Østerud, B.; Olsen, Randi; Ezban, M; Paulssen, Ruth H. Heparin induces synthesis and secretion of tissue factor pathway inhibitor (TFPI) form endothelial cells in vitro. Thrombosis and haemostasis. Supplementum 1999. ISSN 0344-7618.

  • Ermakova, N.V.; Paulssen, Ruth H; Florholmen, Jon. The effect of TNF-alpha on cell growth and PLC-gamma expression in insulin-secreting beta-cells. Diabetologica 1999.s 529 - .

  • Paulssen, Ruth H; Fraeyman, Norbert; Florholmen, Jon. Activation of phospholipase C by cholecystokinin in insulin (beta-TC3)-, Somatostatin (Rin1027-B2) - and glucagon (INR1-G9) - secreting pancreatic cell lines: Identification of different CCK-receptor subtypes and G protein-coupling specificities. The FASEB Journal 1997; Volum 11. ISSN 0892-6638.

  • Jablonski, Greg; Mortensen, B.M.; Paulssen, Ruth H; Lund, Hanne W.; Gordeladze, Jan Oxholm. The effect of uremia and aluminium intoxication on hormone signaling in the osteoblast. Journal of Bone and Mineral Research 1992; Volum 7. ISSN 0884-0431.s 225 - .

  • Paulssen, Ruth H; Paulssen, Eyvind Jakob; Gordeladze, Jan Oxholm; Gautvik, Kaare M. The elucidation of receptor-effector coupling in rat pituitary (GH3) cells by the use of antisense techniques. Journal of Cellular Biochemistry 1991. ISSN 0730-2312.s 26 - .

  • Fenton, Christopher Graham; Taman, Hagar; Florholmen, Jon; Paulssen, Ruth H. Transcriptional profiling of ulcerative colitis in remission. Journal of Crohn's and colitis 2019; Volum 13. ISSN 1873-9946.s S113 - S114.s doi: 10.1093/ecco-jcc/jjy222.179.

  • Fenton, Christopher Graham; Taman, Hagar; Florholmen, Jon; Paulssen, Ruth H. Transcriptional profiling of ulcerative colitis in remission. 14th Congress of ECCO 2019-03-06 - 2019-03-09 2019.

  • Paulssen, Ruth H; Taman, Hagar Mohamed; Fenton, Christopher Graham; Hensel, Inga Viktoria; Anderssen, Endre; Florholmen, Jon. Novel regulatory DNA methylation features of relevance for ulcerative colitis. American Journal of Gastroenterology 2018; Volum 113. ISSN 0002-9270.s doi: 10.1038/ajg2017.452.

  • Paulssen, Ruth H; Taman, Hagar Mohamed; Fenton, Christopher Graham; Hensel, Inga Viktoria; Anderssen, Endre; Florholmen, Jon. Novel regulatory DNA methylation features of relevance for ulcerative colitis. Advances in Inflammatory Bowel Diseases 2017-11-09 - 2017-11-11 2017.

  • Gundersen, Mona Dixon; Goll, Rasmus; Florholmen, Jon; Paulssen, Ruth H. Mucosal healing in active ulcerative colitis treated with infliximab to disease remission. Inflammatory Bowel Diseases 2016; Volum 22. ISSN 1078-0998.s S63 - S64.

  • Paulssen, Ruth H; Goll, Rasmus; Florholmen, Jon. PROFILE: As inflammatory bowel disease grows in global incidence, Dr Jon Florholmen outlines what could help to create a cure. PAN european networks science and technology 2014.

  • Sitras, Vasilis; Fenton, Christopher Graham; Paulssen, Ruth H; VÅrtun, Åse; Acharya, Ganesh. Global gene expression profiling in the first and third trimesters of normal human pregnancy. Placenta 2011; Volum 32 (9). ISSN 0143-4004.s A136 - .

  • Sitras, Vasilis; Fenton, Christopher Graham; Paulssen, Ruth H; VÅrtun, Åse; Acharya, Ganesh. GLOBAL PLACENTAL GENE EXPRESSION PROFILING IN THE FIRST AND THIRD TRIMESTERS OF NORMAL HUMAN PREGNANCY. Placenta 2011; Volum 32 (9). ISSN 0143-4004.s A136 - A136.

  • Hellevik, Turid; Pettersen, Inger; Winberg, Jan-Olof; Berg, Vivian; Paulssen, Ruth H; Bartnes, Kristian; Busund, Lill-Tove; Bremnes, Roy M.; Martinez, Inigo Zubiavrre. The Impact of Ionizing Radiation on the Motility and Matrix Remodelling Properties of Carcinoma-associated Fibroblasts. European Journal of Cancer 2011; Volum 47. ISSN 0959-8049.s S142 - S143.

  • Lund, trine; Hals, Margareth Bergesen; Paulssen, Ruth H; Ytrehus, Kirsti. Increased gene expression diversity between female and male mice hearts after transverse aortic constriction (TAC). Regional forskningskonferanse innen medisin og helse 2009-03-25 - 2009-03-26 2009.

  • Snipstad, Kristin; Fenton, Christopher Graham; Kjaeve, J; Kjæve, Jørn; Anderssen, Endre; Paulssen, Ruth H. New specific molecular targets for radiochemotherapy in colorectal cancer. The FEBS Journal 2009; Volum 276. ISSN 1742-464X.s 121 - 121.

  • Olsen, Karina Standahl; Fenton, CG; Anderssen, Endre; Frøyland, Livar; Paulssen, RH; Lund, E. Associations between serum linolenic acid/alpha-linolenic acid ratio and blood gene expression profiles. The FEBS Journal 2009; Volum 276. ISSN 1742-464X.s 115 - 116.

  • Lund, trine; Hals, Margareth Bergesen; Paulssen, Ruth H; Ytrehus, Kirsti. Increased gene expression diversity between female and male hearts after transverse aortic constriction (TAC). European Journal of Heart Failure. Supplements 2009; Volum 8 (2). ISSN 1567-4215.

  • Lund, trine; Hals, Margareth Bergesen; Paulssen, Ruth H; Ytrehus, Kirsti. Increased gene expression diversity between female and male hearts after transverse aortic constriction (TAC). Heart Failure 2009-05-30 - 2009-06-02 2009.

  • Sitras, Vasilis; Paulssen, Ruth H; Grønaas, HS; Leirvik, Jørn; VÅrtun, Åse; Acharya, Ganesh. Differential Placental Gene Expression in Severe Preeclampsia. Gynekologen 2008; Volum 21 (3). ISSN 0805-2158.s 39 - .

  • Sitras, Vasilis; Paulssen, Ruth H; Grønaas, Halvor; VÅrtun, Åse; Acharya, Ganesh. Placental Gene Expression in Severe Preeclampsia. (Abstracts of the 20th European Congress of Obstetrics and Gynaecology). Acta Obstetrica Ginecologica Portuguesa 2008. ISSN 1646-5830.s 51 - 52.

  • Dumeaux, vanessa; Olsen, Karina Standahl; Leirvik, Jørn; Paulssen, Ruth H; Borresen-Dale, AL; Lund, Eiliv. Variation of gene expression profiles in whole blood from a large representative sample of postmenopausal Norwegian women. European Journal of Cancer 2008; Volum 6. ISSN 0959-8049.s 97 - 97.

  • Sitras, Vasilis; Paulssen, Ruth H; Grønaas, Halvor; Ganesh, Acharya. Gene expression profile in labouring and non-labouring placenta near term. American Journal of Obstetrics and Gynecology 2007; Volum 195. ISSN 0002-9378.

  • Paulssen, Ruth H; Moe, Bjørn; Grønaas, Halvor; Ørbo, Anne. Gene expression in endometrial cancer cells (ishikawa) after short time high dose exposure to progestins. Virchows Archiv 2007; Volum 451. ISSN 0945-6317.s 163 - 164.

  • Mortensen, Elin; Hansen, L; Bjurstam, Nils; Klenow, S; Frantzen, Jan-Ole; Paulssen, Ruth H. Imprint of core biopsies as a reliable diagnostic tool in breast cancer and possible usefullness for research purposes. Breast Cancer Research 2005; Volum 7. ISSN 1465-5411.s 33 - .

  • Paulssen, Ruth H; Sørli, Jorid; Evgenov, Natalia Victorovna; Krum-Hansen, Sanda. Regulation and expression of protein kinase C isoforms by cholecystokinin and gastrin in a somatostatin-secreting pancreatic Rin1027-B2 cell line. European Journal of Biochemistry (EJB) 2001; Volum 268. ISSN 0014-2956.s 103 - .

  • Fraeyman, Norbert; Paulssen, Ruth H. Central role of PKC-alpha in the desensitisation of M3-muscarinic receptors. European Journal of Biochemistry (EJB) 2001; Volum 268. ISSN 0014-2956.s 92 - .

  • Evgenov, Natalia Victorovna; Paulssen, Ruth H; Evgenov, OV; Christiansen, Ingrid B; Florholmen, Jon. Tunor necrosis factor-alpha induces apoptosis in an insulin-secreting beta-cell line. Diabetes Research and Clinical Practice 2000; Volum 50. ISSN 0168-8227.

  • Hansen, J.-B.; Svensson, Birgit; Østerud, B.; Olsen, Randi; Ezban, M; Paulssen, Ruth H. Heparin induces synthesis and secretion of tissue factor pathway inhibitor (TFPI) form endothelial cells in vitro. Thrombosis and haemostasis. Supplementum 1999. ISSN 0344-7618.

  • Ermakova, N.V.; Paulssen, Ruth H; Florholmen, Jon. The effect of TNF-alpha on cell growth and PLC-gamma expression in insulin-secreting beta-cells. Diabetologica 1999.s 529 - .

  • Paulssen, Ruth H; Fraeyman, Norbert; Florholmen, Jon. Activation of phospholipase C by cholecystokinin in insulin (beta-TC3)-, Somatostatin (Rin1027-B2) - and glucagon (INR1-G9) - secreting pancreatic cell lines: Identification of different CCK-receptor subtypes and G protein-coupling specificities. The FASEB Journal 1997; Volum 11. ISSN 0892-6638.

  • Jablonski, Greg; Mortensen, B.M.; Paulssen, Ruth H; Lund, Hanne W.; Gordeladze, Jan Oxholm. The effect of uremia and aluminium intoxication on hormone signaling in the osteoblast. Journal of Bone and Mineral Research 1992; Volum 7. ISSN 0884-0431.s 225 - .

  • Paulssen, Ruth H; Paulssen, Eyvind Jakob; Gordeladze, Jan Oxholm; Gautvik, Kaare M. The elucidation of receptor-effector coupling in rat pituitary (GH3) cells by the use of antisense techniques. Journal of Cellular Biochemistry 1991. ISSN 0730-2312.s 26 - .

  • R.H. Paulssen, E.J. Paulssen, J.O. Gordeladze and K.M. Gautvik: THE ELUCIDATION OF RECEPTOR-EFFECTOR COUPLING IN RAT PITUITARY (GH3) CELLS BY THE USE OF ANTISENSE TECHNIQUES. J.Cell.Biochem. (1991) Suppl. 15D:26.

    G. Jablonski, B.M. Mortensen, R.H. Paulssen, H.W. Lund and J.O. Gordeladze: THE EFFECT OF UREMIA AND ALUMINIUM INTOXICATION ON HORMONE SIGNALING IN THE OSTEOBLAST. J. Bone Miner. Res. (1992), 7 Suppl. 1:225.

    R.H. Paulssen, N. Fraeyman and J. Florholmen: ACTIVATION OF PHOPHOLIPASE C BY CHOLECYSTOKININ IN INSULIN (b-TC3)-, SOMATOSTATIN (Rin1027-B2)- AND GLUCAGON (INR1-G9)- SECRETING PANCREATIC CELL LINES: IDENTIFICATION OF DIFFERENT CCK-RECEPTOR SUBTYPES AND G PROTEIN-COUPLING SPECIFICITIES. FASEB J. (1997), 11 Suppl. 9: 2767.

    N.V. Ermakova, R.H. Paulssen and J. Florholmen: THE EFFECT OF TNF-a ON CELL GROWTH AND PLC-g EXPRESSION IN INSULIN-SECRETING b-CELLS. Diabetologia (1999), 42:529.

     J.B. Hansen, B. Svensson, B. Østerud, R. Olsen, M. Ezban and R.H. Paulssen: HEPARIN INDUCES SYNTHESIS AND SECRETION OF TISSUE FACTOR PATHWAY INHIBITOR (TFPI) FROM ENDOTHELIAL CELLS IN VITRO. Thromb. Haemostasis (1999), Suppl. 92.

    N.V. Evgenov, R.H. Paulssen, O.V. Evgenov, I. Christiansen and J. Florholmen: TUMOR NECROSIS FACTOR-a INDUCES APOPTOSIS IN AN INSULIN-SECRETING b-CELL LINE. Diabetes Res.Clin.Practice (2000), 50:S150.

    R. H. Paulssen, J. Sørli, N.V. Evgenov and S. Krum-Hansen: REGULATION AND EXPRESSION OF PROTEIN KINASE C ISOFORMS BY CHOLECYSTOKININ AND GASTRIN IN A SOMATOSTATIN-SECRETING PANCRETIC Rin1027-B2 CELL LINE. Eur.J.Biochem (2001), 268, Suppl. 1:103.

    N. Fraeyman and R. Paulssen: CENTRAL ROLE OF PKCa IN THE DESENSITISATION OF M3-MUSCARINIC RECEPTORS. Eur.J.Biochem. (2001), 268, Suppl. 1: 92.

    L. Thommesen, E. Hofsli, R.H. Paulssen, M.W. Anthonsen, and A. Lægreid: MOLECULAR MECHANISMS INVOLVED IN GASTRIN MEDIATED REGULATION OF cAMP-RESPONSIVE (CRE) PROMOTOR ELEMENT. Am.J.Physiol. – Endocrinol. And Metab. APStracts (2001), 8:0201E.

    E. Mortensen, L. Hansen, N. Bjurstam, S. Klenow, J.O. Frantzen and R.H. Paulssen: IMPRINT OF CORE BIOPSIES AS A RELIABLE DIAGNOSTIC TOOL IN BREAST CANCER AND POSSIBLE USEFULNESS FOR RESEARCH PURPOSES. Breast Cancer Res. (2005), 7, Suppl.  2:33.

    R.H. Paulssen, L. Olsen, and T.C. Sogn: MagNA PURE COMPACT RNA ISOLATION KIT: ISOLATION OG HIGH-QUALITY TOTAL RNA SAMPLES FROM A BROAD RANGE OF SAMPLE MATERIAL. Biochemica (2006), 2:14-16.

    V. Sitras, R.H. Paulssen, H. Grønaas, and G. Acharya: GENE EXPRESSION PROFILE IN LABORING AND NON-LABORING PLACENTA NEAR TERM.  Am. J. Obst. Gynecol. (2007), 195, Suppl. S197.

    V. Dumeaux, K.S. Olsen, J. Leirvik, R.H. Paulssen, A.L. Borresen-Dale, and E. Lund: VARIATION OF GENE EXPRESSION PROFILES IN WHOLE BLOOD FROM A LARGE REPRESENTATIVE SAMPLE OF POSTMENOPAUSAL NORWEGIAN WOMEN. Eur. J. Cancer (2008), 6, Suppl. 9:97.

    K.S. Olsen, C.G. Fenton, E. Anderssen, L. Frøyland, R.H. Paulssen, and E. Lund: ASSOCIATIONS BETWEEN SERUM LINOLENIC ACID/ALPHA-LINOLENIC ACID RATIO AND BLOOD GENE EXPRESSION PROFILES, FEBS J. (2009), 276, Suppl. 1:115-116.

    K. Snipstad, C.G. Fenton, J. Kjæve, E. Anderssen and R.H. Paulssen: NEW SPECIFIC MOLECULAR TARGETS FOR RADIOCHEMOTHERAPY IN COLORECTAL CANCER, FEBS J. (2009), 276, Suppl. 1:121.

    T. Lund, M.B. Hals, R.H. Paulssen, and K. Ytrehus: INCREASED GENE EXPRESSION DIVERSITY BETWEEN FEMALE AND MALE MICE HEARTS AFTER TRANSVERSE AORTIC CONTRICTION (TAC). Eur. J. Heart Failure Supplements (2009), 8 (2).

    K.S. Olsen, C. Fenton, E. Anderssen, L. Frøyland, R.H. Paulssen, V. Dumeaux, and E. Lund: EEFECTS OF PLASMA FATTY ACID RATIOS ON THE BLOOD TRANSCRIPTOME. Norwegian Journal of Epidemiology (2009), 19: Suppl. 1:9.

    V. Sitras, C. Fenton, R.H. Paulssen, A. Vårtun and G. Acharya: GLOBAL PLACENTAL GENE EXPRESSION PROFILING IN THE FIRST AND THIRD TRIMESTERS OF NORMAL HUMAN PREGNANCY. Placenta (2011), 32: A136, P2.117.

    Electro Cell Manipulator Ô, ECMâ600 Electroporation Protocol 0055, BTX Dicision of  GenetronicsÓ (BTX ID #1130).

    Compendium to User Course  “Introduction to Microarray Technology and Data Analysis” (Annual Issues 2004 -2010).

     FEBS News, Issue 5, September 2008, p. 11.

     FEBS News, Issue 5, October 2009, p. 8-9.

     FEBS News, Issue 4, October 2010, p. 8.

    Compendium to User Course “Introduction to High-Throughput Genomics and Data Analysis” (2012).

     

    [Loading...]