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Institutt for klinisk medisin jfl000@post.uit.no +4777645481 Tromsø

Jon Florholmen


Professor

Stillingsbeskrivelse

Forskningsgruppeleder Gastroenterologi og ernæring (mer informasjon på nettsiden til gruppen)


  • Victoria Therese Isaksen, Maria Larsen, Rasmus Goll, Eyvind Jakob Paulssen, Jon Florholmen :
    Correlations between modest weight loss and leptin to adiponectin ratio, insulin and leptin resensitization in a small cohort of Norwegian individuals with obesity
    Endocrine and Metabolic Science 2023 ARKIV / DOI
  • Wei Meng, Kay-Martin Johnsen, Christopher Graham Fenton, Jon Florholmen, Ruth H Paulssen :
    Anti-apoptotic genes and non-coding RNAs are potential outcome predictors for ulcerative colitis
    Functional & Integrative Genomics 2023 ARKIV / DOI
  • Guanglin Cui, Aping Yuan, Zhigang Pang, Jon Florholmen :
    Differential profile of protumor immunological factors between the tumor site and the tumor-free site – predictive potential of IL-8 and COX2 for colorectal cancer and metastasis
    International Immunopharmacology 2023 ARKIV / DOI
  • Guanglin Cui, Jon Florholmen, Rasmus Goll :
    Could Mucosal TNF Transcript as a Biomarker Candidate Help Optimize Anti-TNF Biological Therapy in Patients With Ulcerative Colitis?
    Frontiers in Immunology 2022 ARKIV / DOI
  • Rasmus Goll, Øystein Kittel Moe, Kay-Martin Johnsen, Renate Weenås Meyer, Joachim Friestad, Mona Dixon Gundersen m.fl.:
    Pharmacodynamic mechanisms behind a refractory state in inflammatory bowel disease
    BMC Gastroenterology 2022 ARKIV / DOI
  • Kay-Martin Johnsen, Jon Florholmen, Øystein Kittel Moe, Mona Dixon Gundersen, Julia Beilfuss, Hege Kileng m.fl.:
    Prediction of long-term remission in patients following discontinuation of anti-TNF therapy in ulcerative colitis: a 10 year follow up study
    BMC Gastroenterology 2022 ARKIV / DOI
  • Mona Dixon Gundersen, Kenneth Bowitz Larsen, Kay-Martin Johnsen, Rasmus Goll, Jon Florholmen, Guttorm Haraldsen :
    Hypo-osmotic stress induces the epithelial alarmin IL-33 in the colonic barrier of ulcerative colitis
    Scientific Reports 2022 ARKIV / DOI
  • Guanglin Cui, Gui Li, Zhigang Pang, Jon Florholmen, Rasmus Goll :
    The presentation and regulation of the IL-8 network in the epithelial cancer stem-like cell niche in patients with colorectal cancer
    Biomedicine & Pharmacotherapy 2022 ARKIV / DOI
  • Jan-Magnus Kvamme, Sveinung Sørbye, Jon Florholmen, Trond S. Halstensen :
    Population-based screening for celiac disease reveals that the majority of patients are undiagnosed and improve on a gluten-free diet
    Scientific Reports 2022 ARKIV / DOI
  • Oddmund Nestegard, Behrouz Moayeri, Fred-Arne Halvorsen, Tor Tønnessen, Sveinung Sørbye, Eyvind Jakob Paulssen m.fl.:
    Helicobacter pylori resistance to antibiotics before and after treatment: Incidence of eradication failure
    PLOS ONE 2022 ARKIV / DOI
  • Guanglin Cui, Zhenfeng Li, Jon Florholmen, Rasmus Goll :
    Dynamic stromal cellular reaction throughout human colorectal adenoma-carcinoma sequence: A role of TH17/IL-17A
    Biomedicine & Pharmacotherapy 2021 ARKIV / DOI
  • Christian Børde Arkteg, Sveinung Wergeland Sørbye, Lene Buhl Riis, Stig Manfred Dalen, Jon Florholmen, Rasmus Goll :
    Real-life evaluation of histologic scores for Ulcerative Colitis in remission
    PLOS ONE 2021 ARKIV / DOI
  • Guanglin Cui, Qingbo Fan, Zhenfeng Li, Rasmus Goll, Jon Florholmen :
    Evaluation of anti-TNF therapeutic response in patients with inflammatory bowel disease: Current and novel biomarkers
    EBioMedicine 13. april 2021 ARKIV / DOI
  • Hagar Taman, Christopher Graham Fenton, Endre Anderssen, Jon Florholmen, Ruth H Paulssen :
    DNA hypo-methylation facilitates anti-inflammatory responses in severe ulcerative colitis
    PLOS ONE 2021 ARKIV / DOI
  • Kristin Kaasen Jørgensen, Guro Løvik Goll, Joseph Sexton, Nils Bolstad, Inge Christoffer Olsen, Øivind Wessel Asak m.fl.:
    Efficacy and safety of CT-P13 in inflammatory bowel disease after switching from originator infliximab: Exploratory analyses from the NOR-SWITCH main and extension trials
    BioDrugs 2020 FULLTEKST / ARKIV / DOI
  • Christian Børde Arkteg, Rasmus Goll, Mona Dixon Gundersen, Endre Anderssen, Christopher Graham Fenton, Jon Florholmen :
    Mucosal gene transcription of ulcerative colitis in endoscopic remission
    Scandinavian Journal of Gastroenterology 2020 ARKIV / DOI
  • Christopher Graham Fenton, Hagar Taman, Jon Florholmen, Sveinung Sørbye, Ruth H Paulssen :
    Transcriptional signatures that define ulcerative colitis in remission
    Inflammatory Bowel Diseases 2020 ARKIV / DOI
  • Leif Kyrre Berg, Rasmus Goll, Erik Fagerli, Judith K Ludviksen, Hilde Fure, Moen Odd Sverre m.fl.:
    Intestinal inflammatory profile shows increase in a diversity of biomarkers in irritable bowel syndrome
    Scandinavian Journal of Gastroenterology 2020 ARKIV / DOI
  • Jon Florholmen, Kay-Martin Johnsen, Renate Weenås Meyer, Trine Olsen, Øystein Kittel Moe, Petter Tandberg m.fl.:
    Discovery and validation of mucosal TNF expression combined with histological score-a biomarker for personalized treatment in ulcerative colitis
    BMC Gastroenterology 2020 ARKIV / DOI
  • Oddmund Nestegard, Kay-Martin Johnsen, Sveinung Sørbye, Fred-Arne Halvorsen, Tor Tønnessen, Eyvind Jakob Paulssen m.fl.:
    Clinical characterization of Helicobacter pylori infected patients 15 years after unsuccessful eradication
    PLOS ONE 23. september 2020 ARKIV / DOI
  • Guanglin Cui, Aping Yuan, Zhenfeng Li, Rasmus Goll, Jon Florholmen :
    ST2 and regulatory T cells in the colorectal adenoma/carcinoma microenvironment: implications for diseases progression and prognosis
    Scientific Reports 2020 ARKIV / DOI
  • Armin Schniers, Rasmus Goll, Yvonne Pasing, Sveinung Sørbye, Jon Florholmen, Terkel Hansen :
    Ulcerative colitis: Functional analysis of the in-depth proteome
    Clinical Proteomics 2019 ARKIV / DOI
  • Maria Arlen Larsen, Victoria Therese Isaksen, Eyvind Jakob Paulssen, Rasmus Goll, Jon Florholmen :
    Postprandial leptin and adiponectin in response to sugar and fat in obese and normal weight individuals
    Endocrine 2019 ARKIV / DATA / FULLTEKST / DOI
  • Joseph Diab, Terkel Hansen, Rasmus Goll, Hans Stenlund, Maria Ahnlund, Einar Jensen m.fl.:
    Lipidomics in ulcerative colitis reveal alteration in mucosal lipid composition associated with the disease state
    Inflammatory Bowel Diseases 2019 ARKIV / DOI
  • Rasmus Goll, Richard Heitmann, Øystein Kittel Moe, Carlsen Katrine, Jon Florholmen :
    Head to head comparison of two commercial fecal calprotectin kits as predictor of Mayo endoscopic sub-score and mucosal TNF expression in ulcerative colitis
    PLOS ONE 02. desember 2019 FULLTEKST / ARKIV / DOI
  • Mona Dixon Gundersen, Rasmus Goll, Christopher Graham Fenton, Endre Anderssen, Sveinung Wergeland Sørbye, Jon Florholmen m.fl.:
    Fibrosis Mediators in the Colonic Mucosa of Acute and Healed Ulcerative Colitis
    Clinical and Translational Gastroenterology 2019 ARKIV / DOI
  • Joseph Diab, Terkel Hansen, Rasmus Goll, Hans Stenlund, Einar Jensen, Thomas Moritz m.fl.:
    Mucosal metabolomic profiling and pathway analysis reveal the metabolic signature of ulcerative colitis
    Metabolites 2019 ARKIV / DOI
  • Hagar Mohamed Taman, Christopher Graham Fenton, Inga Viktoria Hensel, Endre Anderssen, Jon Florholmen, Ruth H Paulssen :
    Transcriptomic Landscape of Treatment-Naïve Ulcerative Colitis
    Journal of Crohn's and Colitis 2018 ARKIV / DOI
  • Maria Arlen Larsen, Victoria Therese Isaksen, Odd Moen, Line Wilsgård, Marian Remjin, Eyvind Jakob Paulssen m.fl.:
    Leptin to adiponectin ratio - A surrogate biomarker for early detection of metabolic disturbances in obesity
    NMCD. Nutrition Metabolism and Cardiovascular Diseases 2018 DOI
  • Hagar Taman, Christopher Graham Fenton, Inga Viktoria Hensel, Endre Anderssen, Jon Florholmen, Ruth H Paulssen :
    Genome-Wide DNA Methylation in Treatment-Naïve Ulcerative Colitis
    Journal - Crohn's and Colitis Foundation of Canada 2018 ARKIV / DOI
  • Joseph Diab, Rania Al-Mahdi, Sandra Gouveia, Terkel Hansen, Einar Jensen, Rasmus Goll m.fl.:
    A Quantitative Analysis of Colonic Mucosal Oxylipins and Endocannabinoids in Treatment-Naïve and Deep Remission Ulcerative Colitis Patients and the Potential Link With Cytokine Gene Expression
    Inflammatory Bowel Diseases 2018 ARKIV / DOI
  • Katrine Carlsen, Lene Buhl Riis, Henriette Elsberg, Louise Maagaard, Tine Thorkilgaard, Sveinung Sørbye m.fl.:
    The sensitivity of fecal calprotectin in predicting deep remission in ulcerative colitis
    Scandinavian Journal of Gastroenterology 2018 DOI
  • Jon Florholmen, Sveinung Sørbye, Trond Sundby Halstensen :
    Stor norsk studie avdekker cøliaki hos mange som ikke visste de hadde det - Intervju Jan-Magnus Kvamme
    https://forskning.no/ 2022
  • Jan-Magnus Kvamme, Trond S. Halstensen, Sveinung Wergeland Sørbye, Jon Florholmen :
    Tema: Forekomst av udiagnostisert cøliaki i Tromsø- undersøkelsen: Hva er betydning av glutenfri diett i denne gruppen?
    2021
  • Maria Arlén Larsen, Rasmus Goll, Jon Florholmen :
    A novel mobile-health platform improves weight-loss outcomes after 6 months in obese individuals
  • Maria Arlén Larsen, Victoria Therese Isaksen, Eyvind Jakob Paulssen, Rasmus Goll, Jon Florholmen :
    Postprandial leptin and adiponectin in response to sugar and fat in obese and normalweight individuals
    2020
  • Joseph Diab, Terkel Hansen, Rasmus Goll, Hans Stenlund, Einar Jensen, Thomas Moritz m.fl.:
    Metabolomics Coupled with Pathway Analysis Reveal the Metabolic Fingerprint in Ulcerative Colitis
    2020
  • Joseph Diab, Terkel Hansen, Rasmus Goll, Hans Stenlund, Einar Jensen, Thomas Moritz m.fl.:
    Metabolomics for improved patient stratification in inflammatory bowel disease: Characterisation of the ulcerative colitis metabolome
    Journal of Crohn's and Colitis 2020 DOI
  • Joseph Diab, Terkel Hansen, Rasmus Goll, Einar Jensen, Thomas Moritz, Jon Florholmen m.fl.:
    DOP15 Metabolomics coupled with pathway analysis characterise metabolic changes in treatment-naive ulcerative colitis patients
    Journal of Crohn's and Colitis 2019 DOI
  • Joseph Diab, Terkel Hansen, Rasmus Goll, Hans Stenlund, Maria Ahnlund, Einar Jensen m.fl.:
    Lipidomics in ulcerative colitis reveal disruption of mucosal lipid composition associated with the disease state
    American Journal of Gastroenterology 2019 DOI
  • Joseph Diab, Terkel Hansen, Rasmus Goll, Einar Jensen, Jon Florholmen, Guro Forsdahl :
    Metabolomics coupled with pathway analysis characterise metabolic changes in treatment-naive ulcerative colitis patients
    2019
  • Joseph Diab, Rania Al-Mahdi, Sandra Gouveia, Terkel Hansen, Einar Jensen, Rasmus Goll m.fl.:
    Analysis of Colonic Mucosal Oxylipins and Endocannabinoids in Inflammatory Bowel Disease
    2019
  • Christopher Graham Fenton, Hagar Taman, Jon Florholmen, Ruth H Paulssen :
    Transcriptional profiling of ulcerative colitis in remission
    2019
  • Christopher Graham Fenton, Hagar Taman, Jon Florholmen, Ruth H Paulssen :
    Transcriptional profiling of ulcerative colitis in remission
    Journal of Crohn's and Colitis 25. januar 2019 ARKIV / DOI
  • Maria Arlén Larsen, Jon Florholmen :
    Early markers of metabolic disease in obesity – A study of postprandial triglycerides, leptin and adiponectin interactions in the view of normal and dysregulated metabolism.
    UiT Norges arktiske universitet 2019
  • Ruth H Paulssen, Hagar Mohamed Taman, Christopher Graham Fenton, Inga Viktoria Hensel, Endre Anderssen, Jon Florholmen :
    Novel regulatory DNA methylation features of relevance for ulcerative colitis
    American Journal of Gastroenterology 2018 DOI
  • Joseph Diab, Rania Al-Mahdi, Sandra Gouveia, Terkel Hansen, Thomas Moritz, Einar Jensen m.fl.:
    A quantitative analysis of colonic mucosal oxylipins and endocannabinoids in Ulcerative Colitis patients and cytokines gene expression
    2018
  • Joseph Diab, Terkel Hansen, Einar Jensen, Terje Vasskog, Rasmus Goll, Jon Florholmen m.fl.:
    Lipidomics and Metabolomics in Inflammatory Bowel Disease: From pathology to clinical development prediction
    2018
  • Joseph Diab, Sandra Gouveia, Terkel Hansen, Einar Jensen, Moritz Thomas, Rasmus Goll m.fl.:
    Altered colonic mucosal oxylipins and endocannabinoids levels in treatment-naive and deep remission Ulcerative Colitis patients
    2018
  • Joseph Diab, Rasmus Goll, Terkel Hansen, Einar Jensen, Thomas Moritz, Jon Florholmen m.fl.:
    Lipidomics in Ulcerative Colitis Reveal Disruption of Mucosal Lipids Composition in Association with the Disease State
    2018

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