
Foto: Andreas Palmén
Annette Bayer
Instituttleder; Professor, Kjemisk syntese og analyse
- Wieske, Lianne H. E.; Bogaerts, Jonathan; Leding, Albin A. M.; Wilcox, Scott; Rasmussen, Anna Andersson; Leszczak, Kinga; Turunen, Lotta; Herrebout, Wouter A.; Hubert, Madlen; Bayer, Annette; Erdelyi, Mate. NMR Backbone Assignment of VIM-2 and Identification of the Active Enantiomer of a Potential Inhibitor. ACS Medicinal Chemistry Letters 2022; Volum 13 (2). ISSN 1948-5875.s 257 - 261.s doi: 10.1021/acsmedchemlett.1c00635.
- Gevorgyan, Ashot; Hopmann, Kathrin Helen; Bayer, Annette. Improved Buchwald-Hartwig Amination by the Use of Lipids and Lipid Impurities. Organometallics 2021. ISSN 0276-7333.s doi: 10.1021/acs.organomet.1c00517.
- Gevorgyan, Ashot; Hopmann, Kathrin Helen; Bayer, Annette. Lipids as Versatile Solvents for Chemical Synthesis. Green Chemistry 2021; Volum 23 (18). ISSN 1463-9262.s 7219 - 7227.s doi: 10.1039/d1gc02311j.
- Paulsen, Marianne Hagensen; Engqvist, Magnus; Ausbacher, Dominik; Anderssen, Trude; Langer, Manuel K-; Haug, Tor; Morello, Glenn Robert; Liikanen, Laura; Blencke, Hans-Matti; Isaksson, Johan; Juskewitz, Eric; Bayer, Annette; Strøm, Morten B.. Amphipathic Barbiturates as Mimics of Antimicrobial Peptides and the Marine Natural Products Eusynstyelamides with Activity against Multi-resistant Clinical Isolates. Journal of Medicinal Chemistry 2021; Volum 64 (15). ISSN 0022-2623.s 11395 - 11417.s doi: 10.1021/acs.jmedchem.1c00734.
- Pavlovic, Ljiljana; Pettersen, Martin; Gevorgyan, Ashot; Vaitla, Janakiram; Bayer, Annette; Hopmann, Kathrin Helen. Computational and experimental insights into asymmetric Rh‐catalyzed hydrocarboxylation with CO2. (fulltekst) (prosjekt) European Journal of Organic Chemistry 2020; Volum 2021. ISSN 1434-193X.s 663 - 670.s doi: 10.1002/ejoc.202001469.
- Guttormsen, Yngve; Fairhurst, Magnus John Espeland; Pandey, Sunil Kumar; Isaksson, Johan; Haug, Bengt Erik; Bayer, Annette. Total synthesis of phorbazole B. (prosjekt) Molecules 2020; Volum 25 (20). ISSN 1420-3049.s 1 - 10.s doi: 10.3390/molecules25204848.
- Ndukwe, Ikenna E.; Lam, Yu-hong; Pandey, Sunil Kumar; Haug, Bengt Erik; Bayer, Annette; Sherer, Edward C.; Blinov, Kirill A.; Williamson, R. Thomas; Isaksson, Johan; Reibarkh, Mikhail; Liu, Yizhou; Martin, Gary E.. Unequivocal structure confirmation of a breitfussin analog by anisotropic NMR measurements. Chemical Science 2020; Volum 11 (44). ISSN 2041-6520.s 12081 - 12088.s doi: 10.1039/d0sc03664a.
- Ismael, Aya; Gevorgyan, Ashot; Skrydstrup, Troels; Bayer, Annette. Renewable solvents for palladium-catalyzed carbonylation reactions. Organic Process Research & Development 2020; Volum 24 (11). ISSN 1083-6160.s 2665 - 2675.s doi: 10.1021/acs.oprd.0c00325.
- Muhammad, Zeeshan; Skagseth, Susann; Boomgaren, Marc; Akhter, Sundus; Frøhlich, Christopher; Ismael, Aya; Christopeit, Tony; Bayer, Annette; Leiros, Hanna-Kirsti S.. Structural studies of triazole inhibitors with promising inhibitor effects against antibiotic resistance metallo-β-lactamases. Bioorganic & Medicinal Chemistry 2020; Volum 28 (15). ISSN 0968-0896.s doi: 10.1016/j.bmc.2020.115598.
- Samuelsen, Ørjan; Åstrand, Ove Alexander Høgmoen; Frøhlich, Christopher; Heikal, Adam; Skagseth, Susann; Carlsen, Trine Josefine Olsen; Leiros, Hanna-Kirsti S.; Bayer, Annette; Schnaars, Christian; Kildahl-Andersen, Geir; Lauksund, Silje; Finke, Sarah; Huber, Sandra; Gjøen, Tor; Andresen, Adriana Magalhaes Santos; Økstad, Ole Andreas; Rongved, Pål. ZN148 Is a Modular Synthetic Metallo-beta-Lactamase Inhibitor That Reverses Carbapenem Resistance in Gram-Negative Pathogens In Vivo. (data) Antimicrobial Agents and Chemotherapy 2020; Volum 64 (6). ISSN 0066-4804.s doi: 10.1128/AAC.02415-19.
- Ismael, Aya; Skrydstrup, Troels; Bayer, Annette. Carbonylative Suzuki-Miyaura couplings of sterically hindered aryl halides: Synthesis of 2-aroylbenzoate derivatives. Organic and biomolecular chemistry 2020; Volum 18 (9). ISSN 1477-0520.s 1754 - 1759.s doi: 10.1039/d0ob00044b.
- Gevorgyan, Ashot; Hopmann, Kathrin Helen; Bayer, Annette. Formal C-H carboxylation of unactivated arenes. Chemistry - A European Journal 2020. ISSN 0947-6539.s 6064 - 6069.s doi: 10.1002/chem.202000515.
- Gevorgyan, Ashot; Hopmann, Kathrin Helen; Bayer, Annette. Exploration of New Biomass-Derived Solvents: Application to Carboxylation Reactions. ChemSusChem 2020. ISSN 1864-5631.s 2080 - 2088.s doi: 10.1002/cssc.201903224.
- Obst, Marc; Gevorgyan, Ashot; Bayer, Annette; Hopmann, Kathrin Helen. Mechanistic Insights into Copper-Catalyzed Carboxylations. Organometallics 2020; Volum 39 (9). ISSN 0276-7333.s 1545 - 1552.s doi: 10.1021/acs.organomet.9b00710.
- Østnes Hansen, Kine; Andersen, Jeanette hammer; Bayer, Annette; Pandey, Sunil Kumar; Lorentzen, Marianne; Jørgensen, Kåre Bredeli; Sydnes, Magne Olav; Guttormsen, Yngve; Baumann, Matthias; Koch, Uwe; Klebl, Bert; Eickhoff, Jan; Haug, Bengt Erik; Isaksson, Johan; Hansen, Espen. Kinase chemodiversity from the Arctic: the breitfussins. Journal of Medicinal Chemistry 2019; Volum 62 (22). ISSN 0022-2623.s 10167 - 10181.s doi: 10.1021/acs.jmedchem.9b01006.
- Vaitla, Janakiram; Bayer, Annette. Sulfoxonium Ylide Derived Metal Carbenoids in Organic Synthesis. Synthesis (Stuttgart) 2019; Volum 51. ISSN 0039-7881.s 612 - 628.s doi: 10.1055/s-0037-1610328.
- Vaitla, Janakiram; Bayer, Annette; Hopmann, Kathrin Helen. Vinyl Sulfoxonium Ylide: A New Vinyl Carbenoid Transfer Reagent for the Synthesis of Heterocycles. (fulltekst) (prosjekt) Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry 2019; Volum 30 (12). ISSN 0936-5214.s 1377 - 1383.s doi: 10.1055/s-0037-1611771.
- Paulsen, Marianne Hagensen; Ausbacher, Dominik; Bayer, Annette; Engqvist, Magnus; Hansen, Terkel; Haug, Tor; Anderssen, Trude; Andersen, Jeanette hammer; Sollid, Johanna U Ericson; Strøm, Morten B.. Antimicrobial activity of amphipathic α,α-disubstituted β-amino amide derivatives against ESBL–CARBA producing multi-resistant bacteria; effect of halogenation, lipophilicity and cationic character. European Journal of Medicinal Chemistry 2019; Volum 183. ISSN 0223-5234.s 111671 - 111682.s doi: 10.1016/j.ejmech.2019.111671.
- Gevorgyan, Ashot; Obst, Marc; Guttormsen, Yngve; Maseras, Feliu; Hopmann, Kathrin Helen; Bayer, Annette. Caesium Fluoride-Mediated Hydrocarboxylation of Alkenes and Allenes: Scope and Mechanistic Insights. Chemical Science 2019; Volum 10. ISSN 2041-6520.s 10072 - 10078.s doi: 10.1039/c9sc02467k.
- Ahkter, Sundus; Lund, Bjarte Aarmo; Ismael, Aya; Langer, Manuel; Isaksson, Johan; Christopeit, Tony; Leiros, Hanna-Kirsti S.; Bayer, Annette. A focused fragment library targeting the antibiotic resistance enzyme - Oxacillinase-48: Synthesis, structural evaluation and inhibitor design. European Journal of Medicinal Chemistry 2018; Volum 145. ISSN 0223-5234.s 634 - 648.s doi: 10.1016/j.ejmech.2017.12.085.
- Fairhurst, Magnus John E.; Muhammad, Zeeshan; Haug, Bengt Erik; Bayer, Annette. Aldol condensations on a 3-alkylidene-2,5-diketopiperazine - synthesis of two marine natural products. Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry 2018; Volum 29 (10). ISSN 0936-5214.s 1303 - 1306.s doi: 10.1055/s-0036-1591755.
- Vaitla, Janakiram; Bayer, Annette; Hopmann, Kathrin Helen. Iron‐Catalyzed Carbenoid Transfer Reactions of Vinyl Sulfoxonium Ylides: An Experimental and Computational Study. (fulltekst) (prosjekt) Angewandte Chemie International Edition 2018; Volum 57 (49). ISSN 1433-7851.s 16180 - 16184.s doi: 10.1002/anie.201810451.
- Paulsen, Marianne Hagensen; Karlsen, Eskil Andre; Ausbacher, Dominik; Anderssen, Trude; Bayer, Annette; Ochtrop, Philipp; Hedberg, Christian; Haug, Tor; Sollid, Johanna U Ericson; Strøm, Morten B.. An amphipathic cyclic tetrapeptide scaffold containing halogenated β2,2-amino acids with activity against multi-resistant bacteria. Journal of Peptide Science 2018; Volum 24 (10). ISSN 1075-2617.s 1 - 11.s doi: 10.1002/psc.3117.
- Pavlovic, Ljiljana; Vaitla, Janakiram; Bayer, Annette; Hopmann, Kathrin Helen. Rhodium-Catalyzed Hydrocarboxylation: Mechanistic Analysis Reveals Unusual Transition State for Carbon–Carbon Bond Formation. (fulltekst) (prosjekt) Organometallics 2018; Volum 37 (6). ISSN 0276-7333.s 941 - 948.s doi: 10.1021/acs.organomet.7b00899.
- Vaitla, Janakiram; Bayer, Annette; Hopmann, Kathrin Helen. Synthesis of Indoles and Pyrroles Utilizing Iridium Carbenes Generated from Sulfoxonium Ylides. Angewandte Chemie International Edition 2017; Volum 56 (15). ISSN 1433-7851.s 4277 - 4281.s doi: 10.1002/anie.201610520.
- Skagseth, Susann; Akhter, Sundus; Paulsen, Marianne H.; Zeeshan, Muhammad; Lauksund, Silje; Samuelsen, Ørjan; Leiros, Hanna-Kirsti S.; Bayer, Annette. Metallo-β-lactamase inhibitors by bioisosteric replacement: preparation, activity and binding. European Journal of Medicinal Chemistry 2017; Volum 135. ISSN 0223-5234.s 159 - 173.s doi: 10.1016/j.ejmech.2017.04.035.
- Vaitla, Janakiram; Guttormsen, Yngve; Mannisto, Jere K.; Nova, Ainara; Repo, Timo; Bayer, Annette; Hopmann, Kathrin Helen. Enantioselective incorporation of CO2: status and potential. (fulltekst) ACS Catalysis 2017; Volum 7 (10). ISSN 2155-5435.s 7231 - 7244.s doi: 10.1021/acscatal.7b02306.
- Skagseth, Susann; Christopeit, Tony; Akhter, Sundus; Bayer, Annette; Samuelsen, Ørjan; Leiros, Hanna-Kirsti S.. Structural insights into TMB-1 and the role of residues 119 and 228 in substrate and inhibitor binding. Antimicrobial Agents and Chemotherapy 2017; Volum 61:e02602-16 (8). ISSN 0066-4804.s 1 - 19.s doi: 10.1128/AAC.02602-16.
- Vaitla, Janakiram; Hopmann, Kathrin Helen; Bayer, Annette. Rhodium-Catalyzed Synthesis of Sulfur Ylides via in Situ Generated Iodonium Ylides. Organic Letters 2017; Volum 19 (24). ISSN 1523-7060.s 6688 - 6691.s doi: 10.1021/acs.orglett.7b03413.
- Hansen, Kine Østnes; Isaksson, Johan; Bayer, Annette; Johansen, Jostein a; Andersen, Jeanette hammer; Hansen, Espen. Securamine Derivatives from the Arctic Bryozoan Securiflustra securifrons. Journal of natural products 2017; Volum 80 (12). ISSN 0163-3864.s 3276 - 3283.s doi: 10.1021/acs.jnatprod.7b00703.
- Lund, Bjarte Aarmo; Christopeit, Tony; Guttormsen, Yngve; Bayer, Annette; Leiros, Hanna-Kirsti S.. Screening and Design of Inhibitor Scaffolds for the Antibiotic Resistance Oxacillinase-48 (OXA-48) through Surface Plasmon Resonance Screening. Journal of Medicinal Chemistry 2016; Volum 59 (11). ISSN 0022-2623.s 5542 - 5554.s doi: 10.1021/acs.jmedchem.6b00660.
- Paulsen, Marianne H.; Engqvist, Magnus; Ausbacher, Dominik; Strøm, Morten B.; Bayer, Annette. Efficient and scalable synthesis of α,α-disubstituted β-amino amides. Organic and biomolecular chemistry 2016; Volum 14 (31). ISSN 1477-0520.s 7570 - 7578.s doi: 10.1039/c6ob01219a.
- Lorentzen, Marianne; Bayer, Annette; Sydnes, Magne Olav; Jørgensen, Kåre Bredeli. Total synthesis of tubastrine and 3-dehydroxy tubastrine by microwave-assisted cross-coupling reactions. Tetrahedron 2015; Volum 71 (43). ISSN 0040-4020.s 8278 - 8284.s doi: 10.1016/j.tet.2015.09.003.
- Demissie, Taye Beyene; Kostenko, Nataliya; Komorovsky, Stanislav; Repisky, Michal; Isaksson, Johan; Bayer, Annette; Ruud, Kenneth. Experimental and four-component relativistic DFT studies of tungsten carbonyl complexes. Journal of Physical Organic Chemistry 2015; Volum 28 (12). ISSN 0894-3230.s 723 - 731.s doi: 10.1002/poc.3476.
- Pandey, Sunil Kumar; Guttormsen, Yngve; Haug, Bengt Erik; Hedberg, Christian; Bayer, Annette. A concise total synthesis of breitfussin A and B. Organic Letters 2015; Volum 17 (1). ISSN 1523-7060.s 122 - 125.s doi: 10.1021/ol503348n.
- Hopmann, Kathrin Helen; Bayer, Annette. Enantioselective imine hydrogenation with iridium-catalysts: Reactions, mechanisms and stereocontrol. Coordination chemistry reviews 2014; Volum 268. ISSN 0010-8545.s 59 - 82.s doi: 10.1016/j.ccr.2014.01.023.
- Hopmann, Kathrin Helen; Frediani, Luca; Bayer, Annette. Iridium-PHOX-mediated alkene hydrogenation: Isomerization influences the stereochemical outcome. Organometallics 2014; Volum 33 (11). ISSN 0276-7333.s 2790 - 2797.s doi: 10.1021/om5002843.
- Lind, Karianne Fredenfeldt; Hansen, Espen; Østerud, Bjarne; Eilertsen, Karl-Erik; Bayer, Annette; Engqvist, Stig Olov Magnus; Leszczak, Kinga; Jørgensen, Trond Ø.; Andersen, Jeanette hammer. Antioxidant and Anti-Inflammatory Activities of Barettin. Marine Drugs 2013; Volum 11 (7). ISSN 1660-3397.s 2655 - 2666.s doi: 10.3390/md11072655.
- Melnes, Silje; Bayer, Annette; Gautun, Odd Reidar. Aryl N-methyliminodiacetic acid (MIDA) boronates from cyclotrimerization of ethynyl MIDA boronate with diynes. Tetrahedron 2013; Volum 69 (37). ISSN 0040-4020.s 7910 - 7915.s doi: 10.1016/j.tet.2013.07.027.
- Kostenko, Nataliya; Eriksson, Anna Cecilia; Engqvist, Stig Olov Magnus; Villa Gonzalez, Susana; Bayer, Annette. Palladium(0)-Catalyzed Cross-Couplings of 2-Bromophosphinine. European Journal of Organic Chemistry 2013; Volum 2013 (22). ISSN 1434-193X.s 4756 - 4759.s doi: 10.1002/ejoc.201300710.
- Melnes, Silje; Bayer, Annette; Gautun, Odd Reidar. Cyclotrimerization of unsymmetrically bromo-substituted diynes: toward the synthesis of potential selective inhibitors of tyrosine kinase 2. Tetrahedron 2012; Volum 68 (40). ISSN 0040-4020.s 8463 - 8471.s doi: 10.1016/j.tet.2012.07.087.
- Hopmann, Kathrin Helen; Bayer, Annette. On the Mechanism of Iridium-Catalyzed Asymmetric Hydrogenation of Imines and Alkenes: A Theoretical Study. Organometallics 2011; Volum 30 (9). ISSN 0276-7333.s 2483 - 2497.s doi: 10.1021/om1009507.
- Endeshaw, Molla Mellese; Bayer, Annette; Hansen, Lars Kr; Gautun, Odd Reidar. Catalytic asymmetric hetero Diels-Alder reactions of N-sulfinyl dienophiles with chiral bis(oxazoline)copper(II) and -zinc(II) triflates. European Journal of Organic Chemistry 2006. ISSN 1434-193X.s 5249 - 5259.s doi: 10.1002/ejoc.200600083.
- Bayer, Annette; Endeshaw, Molla Mellese; Gautun, Odd Reidar. Asymmetric hetero-Diels-Alder reactions of N-sulfinyl dienophiles using chiral bis(oxazoline)-copper(II) and -zinc(II) triflates. Journal of Organic Chemistry 2004; Volum 69. ISSN 0022-3263.s 7198 - 7205.
- Bayer, Annette. Dihydroxylation of Carbon-Carbon Double Bonds. Springer 2004 ISBN 3-540-20983-2.s 21 - 42.
- Bayer, Annette. Aminohydroxylation of Carbon-Carbon Double Bonds. Springer 2004 ISBN 3-540-20983-2.s 43 - 71.
- Källström, Klas; Hedberg, Christian; Brandt, Peter; Bayer, Annette; Andersson, Pher G.. Rationally designed ligands for asymmetric iridium-catalyzed hydrogenation of olefins. Journal of the American Chemical Society 2004; Volum 126. ISSN 0002-7863.s 14308 - 14309.
- Bayer, Annette; Hansen, Lars Kr.; Gautun, Odd Reidar. Asymmetric Diels-Alder reactions of N-sulfinyl dienophiles using chiral Ti(IV)Lewis acids. Tetrahedron: asymmetry 2002; Volum 13. ISSN 0957-4166.s 2407 - 2415.
- Hansen, Lars Kr.; Bayer, Annette; Gautun, Odd Reidar. (1R*,3R*,6S*)-3,6-Dihydro-3,6-dimethyl-2-(toluene-4-sulfonyl)-1(landa)4,2-thiazine 1-oxide. Acta Crystallographica Section E: Structure Reports Online 2002; Volum E58. ISSN 1600-5368.s o198 - o199.
- Hansen, Lars Kr.; Bayer, Annette; Gautun, Odd Reidar. Benzyl (1R*,3S*)-3,6-dihydro-3-methyl-1(landa)4,2-thiazine-2-carboxylate 1-oxide. Acta Crystallographica Section E: Structure Reports Online 2002; Volum E58. ISSN 1600-5368.s o165 - o166.
- Hansen, Lars Kr; Bayer, Annette; Gautun, Odd Reidar. exo-3,6-Dihydro-3-methyl-2-(toluene-4-sulfonyl)-1_4,2-thiazine 1-oxide. Acta Crystallographica Section E: Structure Reports Online 2001; Volum E57. ISSN 1600-5368.s o1109 - o1110.
- Bayer, Annette; Gautun, Odd Reidar. Highly enantioselective hetero Diels-Alder reactions of N-sulfinyl dienophiles promoted by copper(II)- and zinc(II)-chiral bis(oxazoline) complexes. Tetrahedron: asymmetry 2001; Volum 12 (21). ISSN 0957-4166.s 2937 - 2939.
- Bayer, Annette; Svendsen, John Sigurd. Substrate Binding in the Asymmetric Dihydroxylation Reaction � Investigation of the Stereoselectivity in the Dihydroxylation of Cs-Symmetric Divinylcarbinol Derivatives. European Journal of Organic Chemistry 2001. ISSN 1434-193X.s 1769 - 1780.
- Bayer, Annette; Gautun, Odd Reidar. Asymmetric N-sulfinyl dienophile Diels-Alder cycloadditions using chiral Ti(IV)-based Lewis Acids. Tetrahedron Letters 2000; Volum 41. ISSN 0040-4039.s 3743 - 3746.
- Henderson, RJ; Burkow, Ivan C.; Buzzi, M; Bayer, Annette. Effects of docosahexaenoic (22:6n-3), tetracosapentaenoic (24:5n-3) and tetracosahexaenoic (24:6n-3) acids on the desaturation and elongation of n-3 polyunsaturated fatty acids in trout liver microsomes. Biochimica et Biophysica Acta 1998; Volum 1392. ISSN 0006-3002.s 309 - 319.
Medlem i forskningsgruppe
REALF C318