Bilde av Hansen, Jørn H
Bilde av Hansen, Jørn H
Professor Institutt for kjemi jorn.h.hansen@uit.no +4777645992 40768633 Her finner du meg

Jørn H Hansen


Stillingsbeskrivelse

Professor i organisk syntese/medisinalkjemi

Merittert underviser

Leder av Faggruppen for kjemisk syntese og analyse


  • Sindhu Kancherla, Jørn Hedløy Hansen :
    Synthesis of Cryptophanes: Recent Advances
    European Journal of Organic Chemistry 2024 ARKIV / DOI
  • Vijayaragavan Elumalai, Tomaz Trobec, Maja Grundner, Christophe Labriere, Robert Frangez, Kristina Sepcic m.fl.:
    Development of potent cholinesterase inhibitors based on a marine pharmacophore
    Organic and biomolecular chemistry 2022 ARKIV / DOI
  • Aya Ismael, Muhammad Zeeshan, Jørn H Hansen :
    Synthesis of aromatic lactone analogues of Lipoxin A4
    BMC Research Notes 2022 ARKIV / DOI
  • Vijayaragavan Elumalai, Jørn H Hansen :
    Synthesis of 5,7-diarylindoles via Suzuki-Miyaura coupling in water
    Organic and biomolecular chemistry 2021 ARKIV / DOI
  • Lotta Turunen, Jørn H Hansen, Máté Erdélyi :
    Halogen Bonding: An Odd Chemistry?
    The chemical record 2021 FULLTEKST / ARKIV / DOI
  • Christophe Labriere, Gunnar Cervin, Henrik Pavia, Jørn H Hansen, Johan Svenson :
    Structure–Activity Relationship Probing of the Natural Marine Antifoulant Barettin
    Marine Biotechnology 2021 DOI
  • Vijayaragavan Elumalai, Jørn H Hansen :
    A Green, Scalable, and Catalyst-Free One-Minute Synthesis of Quinoxalines
    SynOpen 2021 ARKIV / DOI
  • Christophe Labriere, Vijayaragavan Elumalai, Jannie Staffansson, Gunnar Cervin, Tiffany Le Norcy, Hugo Denardou m.fl.:
    Phidianidine A and Synthetic Analogues as Naturally Inspired Marine Antifoulants
    Journal of natural products 2020 ARKIV / DOI
  • Vijayaragavan Elumalai, Jørn H Hansen :
    A scalable and green one-minute synthesis of substituted phenols
    RSC Advances 2020 ARKIV / DOI
  • Tone Kristoffersen, Vijayaragavan Elumalai, Eliot Starck, Étienne Cousin, Lucille J. Wagner, Stephanie Ramona Hansen m.fl.:
    Microwave‐Assisted Synthesis of Heterocycles from Aryldiazoacetates
    European Journal of Organic Chemistry 2020 ARKIV / FULLTEKST / DATA / DOI
  • Vijayaragavan Elumalai, Jørn H Hansen :
    A Green, Scalable, One-Minute Synthesis of Benzimidazoles
    Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry 2020 ARKIV / DOI
  • Roberto Bartholomeus Wilhelmus Bekker, Richard Fjellaksel, Trine Hjornevik, Syed Nuruddin, Waqas Rafique, Jørn H Hansen m.fl.:
    Discovery of a lead brain-penetrating gonadotropin-releasing hormone receptor antagonist with saturable binding in brain
    ChemMedChem 2020 ARKIV / DOI
  • T. W. Zewde, Dejene Kifle, Jostein a Johansen, Taye Beyene Demissie, Jørn H Hansen, Zenebe Tadesse :
    Cyanobacterial abundance and microcystins in water, seston and fish tissues in Lake Hora-Arsedi (Ethiopia)
    African Journal of Aquatic Science 2020 DOI
  • Jørn H Hansen, Richard Fjellaksel :
    Catalytic Intermolecular Functionalization of Benzimidazoles
    IntechOpen 2019 DOI
  • Samson Tilahun, Demeke Kifle, Tigist W Zewde, Jostein a Johansen, Taye Beyene Demissie, Jørn H Hansen :
    Temporal dynamics of intra-and extra-cellular microcystins concentrations in Koka reservoir (Ethiopia): Implications for public health risk
    Toxicon 2019 ARKIV / DOI
  • Richard Fjellaksel, Angel Moldes-Anaya, Terje Vasskog, Ana Oteiza, Maria Montserrat Martin-Armas, Ole Kristian Hjelstuen m.fl.:
    Evaluation by metabolic profiling and in vitro autoradiography of two promising GnRH‐receptor ligands for brain SPECT imaging
    Journal of labelled compounds & radiopharmaceuticals 08. desember 2019 ARKIV / DOI
  • Christophe Labriere, Jeanette hammer Andersen, Marte Albrigtsen, Jørn H Hansen, Johan Svenson :
    Heterocyclic cellular lipid peroxidation inhibitors inspired by the marine antioxidant barettin
    Bioorganic chemistry (Print) 2018 ARKIV / DOI
  • Christophe Labriere, Nahid Kondori, Josefin Seth Caous, Marc Boomgaren, Kerstin Sandblom, Kristina Nilsson-Ekdahl m.fl.:
    Development and Evaluation of Cationic Amphiphilic Antimicrobial 2,5-Diketopiperazines
    Journal of Peptide Science 2018 DOI
  • Tigist W Zewede, Jostein a Johansen, Demeke Kifle, Taye Beyene Demissie, Jørn H Hansen, Zenebe Tadesse :
    Concentrations of microcystins in the muscle and liver tissues of fish species from Koka reservoir, Ethiopia: A potential threat to public health
    Toxicon 2018 DOI
  • Richard Fjellaksel, Ana Oteiza, Montserrat Martin-Armas, Patrick Riss, Ole Kristian Hjelstuen, Samuel Kuttner m.fl.:
    First in vivo evaluation of a potential SPECT brain radiotracer for the gonadotropin releasing hormone receptor
    BMC Research Notes 2018 ARKIV / DOI
  • Richard Fjellaksel, Damir Dugalic, Taye Beyene Demissie, Patrick Riss, Ole Kristian Hjelstuen, Rune Sundset m.fl.:
    An acylation-Finkelstein approach to radioiodination of bioactives: The role of amide group anchimeric assistance
    Journal of Physical Organic Chemistry 2018 FULLTEKST / ARKIV / DOI
  • Richard Fjellaksel, Rune Sundset, Patrick Riss, Jørn H Hansen :
    Copper-mediated late-stage iodination and 123I-labelling of triazole-benzimidazole bioactives
    Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry 2018 DOI
  • Tone Kristoffersen, Jørn H Hansen :
    3,4-Dihydroquinoxalin-2-ones: recent advances in synthesis and bioactivities
    Chemistry of Heterocyclic Compounds 2017 ARKIV / DOI
  • Richard Fjellaksel, Marc Boomgaren, Rune Sundset, Ira Hebold Haraldsen, Jørn H Hansen, Patrick Riss :
    Small molecule piperazinyl-benzimidazole antagonists of the gonadotropin-releasing hormone (GnRH) receptor
    MedChemComm 2017 ARKIV / DOI
  • Uranbaatar Erdenebileg, Taye Beyene Demissie, Jørn H Hansen :
    Visible-Light Photocatalytic Double C-H Functionalization of Indoles: A Synergistic Experimental and Computational Study
    Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry 2017 ARKIV / DOI
  • Taye Beyene Demissie, Kenneth Ruud, Jørn H Hansen :
    Cryptophanes for Methane and Xenon Encapsulation: A Comparative Density Functional Theory Study of Binding Properties and NMR Chemical Shifts
    Journal of Physical Chemistry A 2017 ARKIV / DOI
  • Yansong Zhao, Jørn H Hansen, Tobias Boström :
    Extraction of magnetic nanoparticles using magnetic ionic liquids
    Micro & Nano Letters 2016 DOI
  • Taye Beyene Demissie, Jørn H Hansen :
    Synergy between Experimental and Computational Approaches to Homogeneous Photoredox Catalysis
    Dalton Transactions 2016 ARKIV / DOI
  • Taye Beyene Demissie, Jørn H Hansen :
    Mechanism and Site-Selectivity in Visible-Light Photocatalyzed C–H Functionalization: Insights from DFT Calculations
    Journal of Organic Chemistry 2016 DOI
  • Karoline Nordli, Hanna Bähr, Mathias Kranz, Angel Moldes-Anaya, Jørn H Hansen :
    Towards a Novel Radiotracer for PET – Imaging of Glioblastoma Targeting the Notch Signaling Pathway
    2023
  • Jørn Hedløy Hansen, Annette Bayer, Marius Myreng Haugland :
    Enhanced teaching and learning outcomes from restructuring a basic organic chemistry course
    Nordic Journal of STEM Education 2023 ARKIV / FULLTEKST
  • Hanna Bähr, Karoline Nordli, Jørn Hedløy Hansen :
    Synthesis of a medetomidine analogue library for antifouling testing
    2023
  • Karoline Nordli, Hanna Bähr, Angel Moldes-Anaya, Jørn H Hansen, Mathias Kranz :
    Towards a novel radiotracer for PET – imaging of glioblastoma targeting the Notch signaling pathway
    2022
  • Hanna Bähr, Jørn Hedløy Hansen :
    Streamlined synthesis of GnRH-R binders and late-stage functionalization
    2020
  • T. W. Zewde, Jostein a Johansen, Demeke Kifle, Taye Beyene Demissie, Jørn H Hansen, Zenebe Tadesse :
    Erratum: ‘Corrigendum to “” [ <153> (<2018>) <85–95>](S0041010118303593)(10.1016/j.toxicon.2018.08.013)
    Toxicon 2019 DOI
  • Uranbaatar Erdenebileg, Jørn H Hansen :
    Selective Photocatalytic Bromination of Indoles
    2018
  • Tone Kristoffersen, Eliot Starck, Stephanie Ramona Hansen, Lucille Wagner, Jørn H Hansen :
    Microwave-assisted synthesis of heterocycles from aryldiazoacetates
    2018
  • Richard Fjellaksel, Ana Oteiza, armas maria montserrat Martin, Jørn H Hansen, Angel Moldes-Anaya, Terje Vasskog m.fl.:
    Development and evaluation of gonadotropin releasing hormone SPECT radioligands
    2018 DATA
  • Mukesh Yadav, Jana Jágerská, Jørn H Hansen, Olav Gaute Hellesø :
    Sensitivity and response time of an on-chip methane sensor
    2017
  • Jana Jágerská, Firehun Tsige Dullo, Susan M. Lindecrantz, Jacqueline Boergers, Jørn H Hansen, Laura Gomez Lechuga m.fl.:
    Cryptophane-Cladded Interferometric Waveguide Sensor for Aqueous Methane Detection
    2017
  • Uranbaatar Erdenebileg, Taye Beyene Demissie, Jørn H Hansen :
    Visible-light photocatalytic C-H functionalization of heterocycles
    2017
  • Marc Boomgaren, Birta Ravdna Sarre, Tor Arne Heim Andberg, Bjørn Olav Brandsdal, Johan Isaksson, Jørn H Hansen :
    Synthesis and exploration of a novel molecular scaffold for dUTPase inhibition: Aiming for new anticancer agents
    2017
  • Richard Fjellaksel, Jørn H Hansen, Angel Moldes-Anaya, armas maria montserrat Martin, Ana Oteiza, Patrick Riss m.fl.:
    Development and evaluation of gonadotropin releasing hormone (GnRH) SPECT radioligands
    2017 FULLTEKST / DATA
  • Martin Ingvaldsen, Jana Jágerská, Firehun Tsige Dullo, Susan M. Lindecrantz, Magnus Engqvist, Jørn H Hansen m.fl.:
    Cryptophane-A doped polymers for methane sensing
    2016
  • Jana Jágerská, Firehun Tsige Dullo, Martin Ingvaldsen, Susan M. Lindecrantz, Magnus Engqvist, Jørn H Hansen m.fl.:
    On-chip methane sensors based on cryptophane-A cladded waveguide interferometers
    2016
  • Jana Jágerská, Firehun Tsige Dullo, Martin Ingvaldsen, Susan M. Lindecrantz, Magnus Engqvist, Jørn H Hansen m.fl.:
    On-Chip Methane Sensing with Cryptophane-A Cladded Waveguide Interferometers
    2016
  • Jana Jágerská, Firehun Tsige Dullo, Martin Ingvaldsen, Susan M. Lindecrantz, Jørn H Hansen, Stian Solbø m.fl.:
    On-chip methane sensing with a cryptophane-A cladded Mach-Zehnder interferometer
    2016
  • Damir Dugalic, Richard Fjellaksel, Marc Boomgaren, Ole Kristian Hjelstuen, Jørn H Hansen :
    Development and validation of gonadotropin releasing hormone receptor SPECT/PET radioligands
    2016
  • Tone Kristoffersen, Eline Samuelsen, Phenias Buhire, Lisa Ramstad, Ane Molden, Taye Beyene Demissie m.fl.:
    Diverse libraries for chemoprospecting and chemical education
    2016
  • Aya Ismael, Muhammad Zeeshan, Jørn H Hansen :
    Novel Synthesis of Lipoxin A4 Analogues
    2016

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    Publikasjoner utenom Cristin

    1. Li, Z.; Boyarskikh, V.; Hansen, J. H.; Musaev, D.; Autschbach, J.; Davies, H. M. L. J. Am. Chem. Soc., 2012,134, 15497.
    2. Hansen, S. R.; Spangler, J.; Hansen, J. H.; Davies, H. M. L. Org. Lett., 2012, 14, 4626.
    3. Qin, C.; Boyarskikh, V.; Hansen, J. H.; Musaev, D. G.; Davies, H. M. L. J. Am. Chem. Soc.,2011133, 19198.
    4. Ovalles, S. R.; Hansen, J. H.; Davies, H. M. L. Org. Lett. 2011,13, 4284-4287
    5. Hansen, J. H.; Gregg, T. M.; Ovalles, S. R.; Lian, Y.; Autschbach, J.; Davies, H. M. L. J. Am. Chem. Soc. 2011, 133, 5076-5085.
    6. Hansen, J. H.; Parr, B. T.; Pelphrey, P.; Jin, Q.; Autschbach, J.; Davies, H. M. L. Angew. Chem., Int. Ed., 2011, 50, 2544-2548.
    7. Hansen, J. H.; Davies, H. M. L. Chem. Sci. 2010, 2, 457-461.
    8. Briones, J.F.; Hansen, J. H.;Hardcastle, K.; Autschbach, J.; Davies, H. M. L. J. Am. Chem. Soc., 2010, 132, 17211.
    9. Pelphrey, P.; Hansen, J.; Davies, H. M. L. Chem. Sci. 2010, 1, 254.
    10. Davies, H. M. L.; Hansen, J. Book chapter in: Catalytic Asymmetric Synthesis 3rd ed. (Ed. Ojima, I.) 2010, p. 163-226.  
    11. Hansen, J.; Li, B.; Autschbach, J.; Dikarev, E. V.; Davies, H. M. L. J. Org. Chem. 2009, 74, 6564-6571.
    12. Hansen, J.; Autschbach, J.; Davies, H. M. L. J. Org. Chem. 2009, 74, 6555-6563.
    13. Sevryugina, Y.; Weaver, B.; Hansen, J.; Thompson, J.; Davies, H. M. L.; Petrukhina, M. A. Organometallics 2008, 27, 1750-1757.
    14. Hansen, J., Davies, H. M. L. Coord. Chem. Rev. 2008, 252, 545-555.


    Forskningsinteresser

    1. Bioaktive heterosykliske forbindelser

    2. Fotoredoks/overgangsmetallkatalyse

    3. Late-stage funksjonalisering

    4. Småmolekylære PET-radiofarmaka

    5. Molekylære sensorer

    Undervisning

    KJE-2003 Introduksjon til analytisk kjemi

    KJE-3314 Organic Chemistry II: Reactions and selectivity

    KJE-3308/8308 Metallorganiske forbindelser i organisk syntese (annethvert år)




    CV

     

     

    UTDANNELSE

    2010

    Ph.D. – Organisk kjemi

    Emory University, Atlanta, GA, USA (Davies Group)

    University at Buffalo, The State University of New York (Davies Group)

    2005

     

    M.Sc./Sivilingeniør  –  Kjemi og bioteknologi,

    Norges Teknisk-Naturvitenskapelige Universitet (NTNU) (Carlsen Group)

    PROFESJONELL ERFARING

    2012 - 2022 Førsteamanuensis, Universitetet i Tromsø

    Sommer 2012

    Foreleser, Touro College, Manhattan, New York City.

    2010-2012 Postdoktor, Princeton University (MacMillan Group)

    2005-2007 Undervisningsassistent, University at Buffalo, The State University of New York