Florian van der Ent,
Susann Skagseth,
Bjarte Aarmo Lund,
Jaka Sočan,
Julia J. Griese,
Bjørn Olav Brandsdal
m.fl.:
Computational design of the temperature optimum of an enzyme reaction
Katarzyna Palica,
Fritz Deufel,
Susann Skagseth,
Gabriela Paula Di Santo Metzler,
Johannes Thoma,
Anna Andersson Rasmussen
m.fl.:
α-Aminophosphonate inhibitors of metallo-β-lactamases NDM-1 and VIM-2
RSC Medicinal Chemistry 2023
DOI
Katarzyna Palica,
Manuela Vorácová,
Susann Skagseth,
Anna Andersson Rasmussen,
Lisa Allander,
Madlen Hubert
m.fl.:
Metallo-β-Lactamase Inhibitor Phosphonamidate Monoesters
Ørjan Samuelsen,
Ove Alexander Høgmoen Åstrand,
Christopher Frøhlich,
Adam Heikal,
Susann Skagseth,
Trine Josefine Olsen Carlsen
m.fl.:
ZN148 Is a Modular Synthetic Metallo-beta-Lactamase Inhibitor That Reverses Carbapenem Resistance in Gram-Negative Pathogens In Vivo
Antimicrobial Agents and Chemotherapy 2020
ARKIV /
DATA /
DOI
Zeeshan Muhammad,
Susann Skagseth,
Marc Boomgaren,
Sundus Akhter,
Christopher Frøhlich,
Aya Ismael
m.fl.:
Structural studies of triazole inhibitors with promising inhibitor effects against antibiotic resistance metallo-β-lactamases
Bioorganic & Medicinal Chemistry 01. august 2020
ARKIV /
DOI
Susann Skagseth,
Sundus Akhter,
Marianne H. Paulsen,
Muhammad Zeeshan,
Silje Lauksund,
Ørjan Samuelsen
m.fl.:
Metallo-β-lactamase inhibitors by bioisosteric replacement: preparation, activity and binding
European Journal of Medicinal Chemistry 2017
ARKIV /
DOI
Susann Skagseth,
Tony Christopeit,
Sundus Akhter,
Annette Bayer,
Ørjan Samuelsen,
Hanna-Kirsti S. Leiros
:
Structural insights into TMB-1 and the role of residues 119 and 228 in substrate and inhibitor binding
Antimicrobial Agents and Chemotherapy 2017
ARKIV /
DOI
Susann Skagseth,
Trine Josefine Olsen Carlsen,
Gro Elin Kjæreng Bjerga,
James Spencer,
Ørjan Samuelsen,
Hanna-Kirsti S. Leiros
:
Role of residues W228 and Y233 in the structure and activity of metallo-β-lactamase GIM-1
Antimicrobial Agents and Chemotherapy 2016
ARKIV /
DOI
Hanna-Kirsti S. Leiros,
Susann Skagseth,
Kine Susann Waade Edvardsen,
Marit Sjo Lorentzen,
Gro Elin Kjæreng Bjerga,
Ingar Leiros
m.fl.:
His224 alters the R2 drug binding site and Phe218 influences the catalytic efficiency of the metallo-β-lactamase VIM-7
Antimicrobial Agents and Chemotherapy 2014
DOI
Vibeke Os,
Susann Skagseth,
Hanna-Kirsti S. Leiros
:
"Superbugs" skal ikke lengre få herje i fred, Vil gjenreise effekten av antibiotika.
Susann Skagseth,
Hanna-Kirsti S. Leiros
:
Forskere vil gjenreise effekten av antibiotika. https://forskning.no/kortnytt/forskere-vil-gjenreise-effekten-av-antibiotika
Susann Skagseth
:
The impact of residue 119 and 228 in the Tripoli metallo-β-lactamase TMB-1 involved in resistance to β-lactam antibiotics" Biostruct conference
2016
Susann Skagseth,
Ørjan Samuelsen,
Hanna-Kirsti S. Leiros
:
The impact of residues 119 and 228 in the Tripoli metallo-beta-lactamase TMB-1 involved in resistance to beta-lactam antibiotics
2016
Tony Christopeit,
Trine Josefine Olsen Carlsen,
Anastasia Albert,
Susann Skagseth,
Hanna-Kirsti S. Leiros
:
Discovery of a Novel Covalent Inhibitor of the Metallo-beta-lactamase NDM-1
2016
Susann Skagseth,
Trine Josefine Olsen Carlsen,
Sundus Akhter,
Muhammad Zeeshan,
Ove Alexander Høgmoen Åstrand,
Annette Bayer
m.fl.:
The fight against metallo-beta-lactamases and antibiotic resistance
2015
Tony Christopeit,
Trine Josefine Olsen Carlsen,
Susann Skagseth,
Bjarte Aarmo Lund,
Ørjan Samuelsen,
Hanna-Kirsti S. Leiros
:
Using fragment screening to identify novel starting points for potent inhibitors of metallo-beta-lactamase VIM-2
2015
Tony Christopeit,
Bjarte Aarmo Lund,
Trine Josefine Olsen Carlsen,
Susann Skagseth,
Ørjan Samuelsen,
Hanna-Kirsti S. Leiros
:
Using Fragment Screening to Identify Novel Starting Points for Potent Carbapenemase Inhibitors
2015
Susann Skagseth,
Trine Josefine Olsen Carlsen,
Sundus Akhter,
Muhammad Zeeshan,
Ove Alexander Høgmoen Åstrand,
Annette Bayer
m.fl.:
The fight against metallo-beta-lactamases and antibiotic resistance
2015
Susann Skagseth,
Trine Josefine Olsen Carlsen,
Tony Christopeit,
Sundus Akhter,
Muhammad Zeeshan,
Ove Alexander Høgmoen Åstrand
m.fl.:
The fight against metallo-beta-lactamases and antibiotic resistance
2015
Susann Skagseth,
Trine Josefine Olsen Carlsen,
Gro Elin Kjæreng Bjerga,
Annette Bayer,
Ørjan Samulesen,
Hanna-Kirsti S. Leiros
:
The importance of residue W228 and Y233 in the metallo-beta-lactamase GIM-1
2014
Marianne H. Paulsen,
Stig Olov Magnus Engqvist,
Ørjan Samuelsen,
Hanna-Kirsti S. Leiros,
Susann Skagseth,
Kinga Leszczak
m.fl.:
Synthesis of potential metallo-beta-lactamase inhibitors
2014
Susann Skagseth,
Trine Josefine Olsen Carlsen,
Gro Elin Kjæreng Bjerga,
Annette Bayer,
Ørjan Samuelsen,
Hanna-Kirsti S. Leiros
:
The importance of residue Trp228 and Tyr233 in the metallo-beta-lactamase GIM-1
2014
Tony Christopeit,
Trine Josefine Olsen Carlsen,
Susann Skagseth,
Bjarte Aarmo Lund,
Ørjan Samuelsen,
Hanna-Kirsti S. Leiros
:
Characterization of substrate and inhibitor binding to different beta-lactamases using Surface Plasmon Resonance based biosensors
2014
Susann Skagseth,
Kine Susann Waade Edvardsen,
Gro Elin Kjæreng Bjerga,
marit sjo Lorentzen,
Ingar Leiros,
Ørjan Samulesen
m.fl.:
Site-directed mutagenesis of metallo-beta-lactamase VIM-7 from the opportunistic human pathogenic bacteria Pseudomonas aeruginosa
2013