Bilde av Brækkan, Sigrid Kufaas
Bilde av Brækkan, Sigrid Kufaas
Institutt for klinisk medisin sigrid.brakkan@uit.no +4777625106 +47 957 47627

Sigrid Kufaas Brækkan


Professor

Stillingsbeskrivelse

Professor, Tromboseforskning (TREC)

 


  • Carl-Arne Arnesen, Line Holtet Evensen, Kristian Hveem, Maiken Elvestad Gabrielsen, John Bjarne Hansen, Sigrid Kufaas Brækkan :
    Proportion of venous thromboembolism attributed to recognized prothrombotic genotypes in men and women
    Research and Practice in Thrombosis and Haemostasis (RPTH) 2024 DOI
  • Vania Maris Morelli, Omri Snir, Kristian Dalsbø Hindberg, Kristian Hveem, Sigrid Kufaas Brækkan, John Bjarne Hansen :
    High microRNA-145 plasma levels are associated with decreased risk of future incident venous thromboembolism: the HUNT study
    Blood 2024 DOI
  • Paul S. de Vries, Paula Reventun, Michael R. Brown, Adam S. Heath, Jennifer E. Huffman, Ngoc-Quynh Le m.fl.:
    A genetic-association study of circulating coagulation factor VIII and von Willebrand factor levels
    Blood 2024 DOI
  • Birgitte Gladsø Tøndel, Joakim Knutsen Sejrup, Vania Maris Morelli, Maja-Lisa Løchen, Inger Njølstad, Ellisiv B. Mathiesen m.fl.:
    Joint effect of ischemic stroke and obesity on the risk of venous thromboembolism: the Tromsø Study
    Research and Practice in Thrombosis and Haemostasis (RPTH) 2024 DOI
  • loannis T. Farmakis, Stefano Barco, Lukas Hobohm, Sigrid Kufaas Brækkan, Jean M. Connors, George Giannakoulas m.fl.:
    Maternal mortality related to pulmonary embolism in the United States, 2003–2020
    American Journal of Obstetrics & Gynecology MFM (AJOG MFM) 2023 ARKIV / DOI
  • Espen Waage Skjeflo, Line Holtet Evensen, Søren Beck Jensen, Nadezhda Latysheva, Annika Elisabet Michelsen, Thor Ueland m.fl.:
    Complement factors B, D, C3bBbP and risk of future venous thromboembolism
    Clinical Immunology 2023 ARKIV / DOI
  • Steven P. Grover, Tomohiro Kawano, Jun Wan, Pansakorn Tanratana, Zsofia Polai, Young J. Shim m.fl.:
    C1 inhibitor deficiency enhances contact pathway–mediated activation of coagulation and venous thrombosis
    Blood 2023 ARKIV / DOI
  • Magnus Edvardsen, Ellen-Sofie Hansen, Thor Ueland, Pål Aukrust, Sigrid Kufaas Brækkan, Vania Maris Morelli m.fl.:
    Impact of the von Willebrand factor-ADAMTS-13 axis on the risk of future venous thromboembolism
    Journal of Thrombosis and Haemostasis 2023 ARKIV / DOI
  • Steven P. Grover, Omri Snir, Kristian Dalsbø Hindberg, Tatianna M. Englebert, Sigrid Kufaas Brækkan, Vania Maris Morelli m.fl.:
    High plasma levels of C1-inhibitor are associated with lower risk of future venous thromboembolism
    Journal of Thrombosis and Haemostasis 2023 ARKIV / DOI
  • Monique J.T. Crobach, Rayna J.S. Anijs, Sigrid Kufaas Brækkan, Marianne T. Severinsen, Jens Hammerstrøm, Hanne Skille m.fl.:
    Survival after cancer-related venous thrombosis: the Scandinavian Thrombosis and Cancer Study
    Blood Advances 2023 ARKIV / DOI
  • Dana Meknas, Sigrid Kufaas Brækkan, John Bjarne Hansen, Vania Maris Morelli :
    Surgery As a Trigger for Incident Venous Thromboembolism: Results from a Population-Based Case-Crossover Study
    TH Open 2023 ARKIV / DOI
  • Oda Leknessund, Vania Maris Morelli, John Bjarne Hansen, Sigrid Kufaas Brækkan :
    Hand grip strength in venous thromboembolism: risk of recurrence and mortality
    Research and Practice in Thrombosis and Haemostasis (RPTH) 2023 ARKIV / DOI
  • Camilla Tøvik Jørgensen, Mazdak Tavoly, Elise Førsund, Heidi Hassel Pettersen, Eirik Tjønnfjord, Waleed Ghanima m.fl.:
    Incidence of bleeding and recurrence in isolated distal deep vein thrombosis: findings from the Venous Thrombosis Registry in Østfold Hospital
    Journal of Thrombosis and Haemostasis 2023 ARKIV / DOI
  • Camilla Tøvik Jørgensen, Sigrid Kufaas Brækkan, Eli Førsund, Heidi Hassel Pettersen, Eirik Tjønnfjord, Waleed Ghanima m.fl.:
    Incidence of venous thromboembolism, recurrence, and bleeding after isolated superficial vein thrombosis: findings from the Venous Thrombosis Registry in Østfold Hospital
    Journal of Thrombosis and Haemostasis 2023 ARKIV / DOI
  • Sigrid Kufaas Brækkan, John Bjarne Hansen :
    VTE epidemiology and challenges for VTE prevention at the population level: VTE epidemiology
    Thrombosis Update 2023 ARKIV / DOI
  • Samantha Swamy, Thor Ueland, John Bjarne Hansen, Omri Snir, Sigrid Kufaas Brækkan :
    Plasma levels of P-selectin and future risk of incident venous thromboembolism
    Journal of Thrombosis and Haemostasis 2023 ARKIV / DOI
  • Tobias Frischmuth, Birgitte Gladsø Tøndel, Sigrid Kufaas Brækkan, John Bjarne Hansen, Vania Maris Morelli :
    The Risk of Incident Venous Thromboembolism Attributed to Overweight and Obesity: The Tromso Study
    Thrombosis and Haemostasis 2023 ARKIV / DOI
  • Maria A. De Winter, Harry R. Büller, Marc Carrier, Alexander T. Cohen, John Bjarne Hansen, Karin A. H. Kaasjager m.fl.:
    Recurrent venous thromboembolism and bleeding with extended anticoagulation: the VTE-PREDICT risk score
    European Heart Journal 2023 ARKIV / DOI
  • Vårin Eiriksdatter Wikan, Birgitte Gladsø Tøndel, Vania Maris Morelli, Ellen Elisabeth Brodin, Sigrid Kufaas Brækkan, John Bjarne Hansen :
    Diagnostic Blood Biomarkers for Acute Pulmonary Embolism: A Systematic Review
    Diagnostics (Basel) 2023 ARKIV / DOI
  • Fridtjof Balteskard Rinde, Camilla Tøvik Jørgensen, Heidi Hassel Pettersen, John Bjarne Hansen, Waleed Ghanima, Sigrid Kufaas Brækkan :
    Low D-dimer levels at diagnosis of venous thromboembolism are associated with reduced risk of recurrence: data from the TROLL registry
    Journal of Thrombosis and Haemostasis 2023 ARKIV / DOI
  • Ellen-Sofie Hansen, Magnus Edvardsen, Pål Aukrust, Thor Ueland, John Bjarne Hansen, Sigrid Kufaas Brækkan m.fl.:
    Combined effect of high factor VIII levels and high mean platelet volume on the risk of future incident venous thromboembolism
    Journal of Thrombosis and Haemostasis 2023 ARKIV / DOI
  • Florian Thibord, Derek Klarin, Jennifer A. Brody, Ming-Huei Chen, Michael G. Levin, Daniel I. Chasman m.fl.:
    Cross-Ancestry Investigation of Venous Thromboembolism Genomic Predictors
    Circulation 2022 ARKIV / DOI
  • Elias Allarai, Wei-Hsuan Lee, Stephen Burgess, Susanna C. Larsson, Sara Lindstrom, Lu Wang m.fl.:
    Genetically predicted cortisol levels and risk of venous thromboembolism
    PLOS ONE 2022 ARKIV / DOI
  • Line Holtet Evensen, Carl-Arne Arnesen, Frits Richard Rosendaal, Maiken Elvestad Gabrielsen, Ben Michael Brumpton, Kristian Hveem m.fl.:
    The Risk of Venous Thromboembolism Attributed to Established Prothrombotic Genotypes
    Thrombosis and Haemostasis 2022 ARKIV / DOI
  • Camilla Tøvik Jørgensen, Mazdak Tavoly, Heidi Hassel Pettersen, Eli Førsund, Christina Roaldsnes, Magnus Kringstad Olsen m.fl.:
    The venous thrombosis registry in Østfold Hospital (TROLL registry) - design and cohort description
    Research and Practice in Thrombosis and Haemostasis (RPTH) 2022 ARKIV / DOI
  • Lisa Jakobsen, Tobias Frischmuth, Sigrid Kufaas Brækkan, John Bjarne Hansen, Vania Maris Morelli :
    Joint Effect of Multiple Prothrombotic Genotypes and Mean Platelet Volume on the Risk of Incident Venous Thromboembolism
    Thrombosis and Haemostasis 2022 ARKIV / DOI
  • Oda Leknessund, Vania Maris Morelli, Bjørn Heine Strand, John Bjarne Hansen, Sigrid Kufaas Brækkan :
    Hand grip strength and risk of incident venous thromboembolism: The Tromsø study
    Research and Practice in Thrombosis and Haemostasis (RPTH) 2022 FULLTEKST / ARKIV / DOI
  • Christabel Esi Damoah, Omri Snir, Kristian Dalsbø Hindberg, Peter Garred, Judith K Ludviksen, Sigrid Kufaas Brækkan m.fl.:
    High Levels of Complement Activating Enzyme MASP-2 Are Associated With the Risk of Future Incident Venous Thromboembolism
    Arteriosclerosis, Thrombosis and Vascular Biology 2022 ARKIV / DOI
  • Omri Snir, line Wilsgård, Nadezhda Latysheva, Casper Ullsten-Wahlund, Sigrid Kufaas Brækkan, Kristian Dalsbø Hindberg m.fl.:
    Plasma levels of platelet-derived microvesicles are associated with risk of future venous thromboembolism
    Journal of Thrombosis and Haemostasis 2022 ARKIV / DOI
  • Helle Jørgensen, Erzsebet Horvath-Puho, Kristina Laugesen, Sigrid Kufaas Brækkan, John Bjarne Hansen, Henrik Toft Sørensen :
    Venous thromboembolism and risk of depression: a population-based cohort study
    Journal of Thrombosis and Haemostasis 2022 ARKIV / DOI
  • Aniket Mishra, Rainer Malik, Tsuyoshi Hachiya, Tuuli Jürgenson, Shinichi Namba, Daniel C. Posner m.fl.:
    Stroke genetics informs drug discovery and risk prediction across ancestries
    Nature 2022 ARKIV / DOI
  • Tobias Frischmuth, Kristian Hindberg, Pål Aukrust, Thor Ueland, Sigrid Kufaas Brækkan, John Bjarne Hansen m.fl.:
    Elevated plasma levels of plasminogen activator inhibitor-1 are associated with risk of future incident venous thromboembolism
    Journal of Thrombosis and Haemostasis 2022 ARKIV / DOI
  • Helle Jørgensen, Erzsébet Horváth-Puhó, Kristina Laugesen, Sigrid Kufaas Brækkan, John Bjarne Hansen, Henrik Toft Sørensen :
    The Interaction Between Venous Thromboembolism and Socioeconomic Status on the Risk of Disability Pension
    Clinical Epidemiology 2022 ARKIV / DOI
  • Birgitte Gladsø Tøndel, Vania Maris Morelli, John Bjarne Hansen, Sigrid Kufaas Brækkan :
    Risk factors and predictors for venous thromboembolism in people with ischemic stroke: A systematic review
    Journal of Thrombosis and Haemostasis 11. juli 2022 ARKIV / DOI
  • Joakim Knutsen Sejrup, Birgitte Gladsø Tøndel, Vania Maris Morelli, Maja-Lisa Løchen, Inger Njølstad, Ellisiv B. Mathiesen m.fl.:
    Joint effect of myocardial infarction and obesity on the risk of venous thromboembolism: The Tromsø Study
    Journal of Thrombosis and Haemostasis 2022 ARKIV / DOI
  • Helle Jørgensen, Erzsebet Horvath-Puho, Kristina Laugesen, Sigrid Kufaas Brækkan, John Bjarne Hansen, Henrik Toft Sørensen :
    Socioeconomic status and risk of incident venous thromboembolism
    Journal of Thrombosis and Haemostasis 2021 DOI
  • Gro Grimnes, Soerajja Bhoelan, Kristian Hindberg, Mark Davids, Max Nieuwdorp, Tom E. Mollnes m.fl.:
    Impact of a Vancomycin-Induced Shift of the Gut Microbiome in a Gram-Negative Direction on Plasma Factor VIII:C Levels: Results from a Randomized Controlled Trial
    Thrombosis and Haemostasis 2021 ARKIV / DOI
  • Helle Jørgensen, Erzsébet Horváth-Puhó, Kristina Laugesen, Sigrid Kufaas Brækkan, John-Bjarne Hansen, Henrik Toft Sørensen :
    Risk of a permanent work-related disability pension after incident venous thromboembolism in Denmark: A population-based cohort study
    PLoS Medicine 2021 ARKIV / DOI
  • Hanne Skille, Benedikte Paulsen, Kristian Hveem, Marianne T. Severinsen, Maiken Elvestad Gabrielsen, Søren R. Kristensen m.fl.:
    Prothrombotic genotypes and risk of venous thromboembolism in occult cancer
    Thrombosis Research 2021 ARKIV / DOI
  • Magnus Edvardsen, Kristian Hindberg, Ellen-Sofie Hansen, Vania Maris Morelli, Thor Ueland, Pål Aukrust m.fl.:
    Plasma levels of von Willebrand factor and future risk of incident venous thromboembolism
    Blood Advances 2021 ARKIV / DOI
  • Benedikte Paulsen, Olga Vikhammer Gran, Marianne T. Severinsen, Jens Hammerstrøm, Søren Risom Kristensen, Suzanne C. Cannegieter m.fl.:
    Association of smoking and cancer with the risk of venous thromboembolism: the Scandinavian Thrombosis and Cancer cohort
    Scientific Reports 21. september 2021 ARKIV / DOI
  • Helle Jørgensen, Erzsébet Horváth-Puhó, Kristina Laugesen, Sigrid Brækkan, John-Bjarne Hansen, Henrik Toft Sørensen :
    Socioeconomic status and risk of incident venous thromboembolism
    Journal of Thrombosis and Haemostasis 2021 ARKIV / DOI
  • Ellen-Sofie Hansen, Magnus Edvardsen, Pål Aukrust, Thor Ueland, John Bjarne Hansen, Sigrid Kufaas Brækkan m.fl.:
    Galectin-3-binding protein and future venous thromboembolism
    Research and Practice in Thrombosis and Haemostasis (RPTH) 2024 DOI
  • Steven P. Grover, Sigrid Kufaas Brækkan, Nigel Mackman, John Bjarne Hansen :
    “High plasma levels of C1-inhibitor are associated with lower risk of future venous thromboembolism”: reply
    Journal of Thrombosis and Haemostasis 2023 DOI
  • Steven P. Grover, Linda Sundler Björkman, Sigrid Kufaas Brækkan, Bengt Zöller, John Bjarne Hansen, Nigel Mackman :
    “C1-inhibitor levels and Venous Thromboembolism: Results from a Mendelian Randomization Study”: comment from Grover et al
    Journal of Thrombosis and Haemostasis 2023 DOI
  • Sigrid Kufaas Brækkan :
    Blodproppforskning - kvinnehelse
    17. mars 2021
  • Sigrid Kufaas Brækkan :
    Thea (21) fikk blodpropp - etterlyser mer forskning
    05. april 2021
  • Sigrid Kufaas Brækkan :
    NRK reportasje blodproppforskning
    06. april 2021
  • Sigrid Kufaas Brækkan :
    Haga fikk blodpropp under samling: – Det var et sjokk
    16. april 2021
  • Sigrid Kufaas Brækkan :
    Arvelig blodpropp: Dette sier ekspertene om corona-vaksinering
    31. mars 2021

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    CV

    Utdanning/Grad

    2010       PhD i Helsefag, Universitetet i Tromsø

    2005       Master i Farmasi, Universitetet i Tromsø

      

    Tidligere akademiske stillinger

    2012-13  Postdoktor, Dep. of Clinical Epidemiology, Leiden University Medical Center, Nederland   

    2010-12  Postdoktor, Hematologisk forskningsgruppe, Universitetet i Tromsø (Helse-Nord midler)

    2008-09  Universitetslektor, Avd for Farmakologi, Institutt for Farmasi, UiT

    2006-08  PhD-student, Center for Atherothrombotic Research in Tromsø, UiT 

    2005-06  Universitetslektor, Avd for Farmakologi, Institutt for Farmasi, UiT

     

    Publikasjoner

    >150 fagfellevurderte originalartikler indeksert i PubMed. Har bidratt til mer enn 200 abstracts presentert og publisert i forbindelse med internasjonale vitenskapelige kongresser.

     

    Priser og utmerkelser

    Young Investigator Award ISTH2016 (International Society of Thrombosis and Haemostasis)

    Helsefaks pris til yngre forsker 2017

     

     

    Veiledning av PhD-studenter

    Fullførte doktorgrader: Hovedveileder: 4; Biveileder: 20

    Pågående doktorgrader: Hovedveileder for 4 og biveileder for 7