Mathias Kranz
Stillingsbeskrivelse
I am currently a Researcher and Principal Investigator (PI) at the Tumor Biology Research Group within the Institute for Medical Biology at UiT – The Arctic University of Norway. My work is supported by a prestigious TFS/TMS Starting Grant for the NORTHCARE project, which focuses on novel theranostic applications of radiotherapeutics for personalized cancer treatment. This project leverages focused ultrasound and advanced imaging modalities, such as Positron Emission Tomography (PET), to explore innovative therapeutic strategies for glioblastoma, one of the most aggressive forms of brain cancer.
In addition, I serve as a PI at the Norwegian Nuclear Medicine Consortium (180°N) at the Department of Diagnostic Services, University Hospital North Norway (UNN). My responsibilities include the development and preclinical evaluation of radiopharmaceuticals, PET/MR imaging of brain tumors, and investigations into the tumor microenvironment. This role integrates advanced molecular imaging techniques with therapeutic development to improve cancer diagnosis and treatment precision.
My work is characterized by a translational approach, bridging fundamental research with clinical applications, and fostering collaborations with international institutions. I also actively supervise PhD and Master’s students, contribute to academic teaching, and maintain a commitment to advancing radiotheranostic research for the benefit of cancer patients globally.
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Forskningsinteresser
My research lies at the intersection of molecular imaging, radiopharmaceutical development, and personalized cancer therapy, with a special emphasis on glioblastoma, one of the most aggressive forms of brain cancer. My primary focus is on radiotheranostics—an innovative field combining diagnostic imaging and targeted therapy to enhance treatment precision and minimize side effects. By coupling radioactive elements with molecules that bind specifically to cancer cells, my work aims to improve both the detection and localized treatment of tumors, reducing collateral damage to healthy tissues.
I am deeply invested in translating preclinical discoveries into clinical applications. My research integrates cutting-edge imaging modalities, such as Positron Emission Tomography (PET) and Magnetic Resonance Imaging (MRI), to explore tumor microenvironments and evaluate novel radiotracers. A key area of interest is developing theranostic agents that exploit molecular targets, enabling both visualization and therapeutic intervention in cancers like glioblastoma.
Beyond glioblastoma, I am interested in advancing methodologies that bridge fundamental research and clinical practice, particularly in radiotracer development and dosimetry. My projects have involved collaborations with international institutions such as Yale University, Helmholtz-Zentrum Dresden-Rossendorf, and Mahidol University, allowing me to explore diverse approaches to radiotherapy and molecular imaging.
Through innovative research and multidisciplinary collaborations, I aim to address the critical challenges in oncology, fostering breakthroughs that improve outcomes for cancer patients worldwide.
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Medlem i prosjekt
CV
Employment history
Current
2025- Researcher and PI (TFS/TMS Starting Grant)
Institute for Medical Biology, Tumor Biology Research Group, UiT The Arctic University of Norway
2019- Researcher and PI (180°N Norwegian Consortium in Nuclear Medicine)
Dept. of Diagnostic Services, UNN/PET center/ UiT-IKM, Nuclear Medicine and Radiation Biology.
Previous
2016-2018 Post doc at Helmholtz-Zentrum Dresden-Rossendorf, Leipzig, Germany
2016-2017 Visiting researcher at Yale university, PET center, New Haven, CT, USA
2012-2016 PhD in Biomedicine at Helmholtz-Zentrum Dresden-Rossendorf, Neuro-Radiopharmaceuticals (Development and animal testing of brain/cancer radiotracers)
Education
2010-2012 M.Sc. Biomedical Engineering, Technical University of Ilmenau, Germany
2006-2010 B.Sc. Biomedical Engineering, Technical University of Ilmenau, Germany/ ERASMUS: Technical University of Košice, Slowakia
Full CV see "vedlegg"
Vedlegg:
- CV_KRANZ_short_3p (pdf)