Mette Kjær
Christof Geisen,
Erika Fleck,
Stephan Martin Gastón Schäfer,
Carmen Walter,
Susanne Braeuninger,
Jens Søndergaard Jensen
m.fl.:
A Phase 1b PK/PD Study to Demonstrate Antigen Elimination with RLYB212, a Monoclonal Anti-HPA-1a Antibody for FNAIT Prevention
Eirik Lind Irgens,
Gunnhild Berglen,
Tore Christoffersen,
Anita Pettersen Henninen,
Rune Hermann Hermansen,
Maret Risten Eira Karlsen
m.fl.:
Our health, our research. Identifying public health research priorities among children and youth in a multiethnic population: Protocol for a community-based participatory health research priority survey
Christof Geisen,
Mette Kjær,
Erika Fleck,
Bjørn Skogen,
Roisin Armstrong,
Frank Behrens
m.fl.:
An HPA-1a–positive platelet–depleting agent for prevention of fetal and neonatal alloimmune thrombocytopenia: a randomized, single-blind, placebo–controlled, single-center, phase 1/2 proof-of-concept study
Mette Kjær,
Christof Geisen,
Cigdem Ahaein Akkøk,
Agneta Wikman,
Ulrich Sachs,
James B. Bussel
m.fl.:
Strategies to develop a prophylaxis for the prevention of HPA-1a immunization and fetal and neonatal alloimmune thrombocytopenia
Jesper Dahl,
Bjørn Skogen,
Mette Kjær,
Anne Husebekk,
Jens Kjeldsen-Kragh,
Heidi Tiller
:
A combined effect of anti-HPA-1a and anti-HLA Class I in pregnancy?
Jens Kjeldsen-Kragh,
Dean Fergusson,
Mette Kjær,
Lani Lieberman,
Andreas Greinacher,
Michael F. Murphy
m.fl.:
Fetal/neonatal alloimmune thrombocytopenia: A systematic review of impact of HLA-DRB3∗01:01 on fetal/neonatal outcome
Maria Averina,
Tor Hervig,
Sandra Huber,
Mette Kjær,
Einar Klæboe Kristoffersen,
Bjørn Johan Bolann
:
Environmental pollutants in blood donors: The multicentre Norwegian donor study
Lani Lieberman,
Andreas Greinacher,
Michael F. Murphy,
James Bussel,
Tamam Bakchoul,
Stacy Corke
m.fl.:
Fetal and neonatal alloimmune thrombocytopenia: recommendations for evidence-based practice, an international approach
British Journal of Haematology 2019 DOI
Jillian M. Baker,
Nadine Shehata,
James Bussel,
Michael F. Murphy,
Andreas Greinacher,
Tamam Bakchoul
m.fl.:
Postnatal intervention for the treatment of FNAIT: a systematic review
Journal of Perinatology 2019 DOI
Jens Kjeldsen-Kragh,
Thomas Larsen Titze,
Benedicte Alexandra Lie,
John T. Vaage,
Mette Kjær
:
HLA-DRB3*01:01 exhibits a dose-dependent impact on HPA-1a antibody levels in HPA-1a-immunized women
Mette Kjær,
Gerald Bertrand,
Tamam Bakchoul,
Edwin Massey,
Jillian Baker,
Lani Lieberman
m.fl.:
Maternal HPA-1a antibody level and its role in predicting the severity of Fetal/Neonatal Alloimmune Thrombocytopenia: a systemic review
Vox Sanguinis 2018 DOI
Mariana Eksteen,
Gøril Heide,
Heidi Tiller,
Yan Zhou,
Nora Hersoug Nedberg,
Inigo Zubiavrre Martinez
m.fl.:
Anti-human platelet antigen (HPA)-1a antibodies may affect trophoblast functions crucial for placental development: A laboratory study using an in vitro model
Dian Winkelhorst,
Michael F. Murphy,
Andreas Greinacher,
Nadine Shehata,
Taman Bakchoul,
Edwin Massey
m.fl.:
Antenatal management in fetal and neonatal alloimmune thrombocytopenia: A systematic review
Blood 2017 DOI
Mette Kjær,
Heidi Tiller,
Gøril Heide,
Jens Kjeldsen-Kragh,
Bjørn Ragnar Skogen,
Anne Husebekk
:
Fetal exposure to maternal human platelet antigen-1a does not induce tolerance. An analytical observational study
Anette Mörtberg,
Stephan Meinke,
Petra Berg,
Mette Kjær,
Jens Kjeldsen-Kragh,
Kerstin Järås
m.fl.:
Sensitive detection of platelet-specific antibodies with a modified MAIPA using biotinylated antibodies and streptavidin-coated beads
Journal of Immunological Methods (JIM) 2016 DOI
Ying-Jan Weng,
Anne Husebekk,
Bjørn Ragnar Skogen,
Mette Kjær,
Liang-Tzung Lin,
Thierry Burnouf
:
Anti-human platelet antigen-1α immunoglobulin G preparation intended to prevent fetal and neonatal alloimmune thrombocytopenia
Heidi Tiller,
Anne Husebekk,
Bjørn Ragnar Skogen,
Jens Kjeldsen-Kragh,
Mette Kjær Killie
:
True risk of fetal/neonatal alloimmune
thrombocytopenia in subsequent pregnancies:
a prospective observational follow-up study
BJOG: An International Journal of Obstetrics and Gynaecology 2016 DOI
Mariana Eksteen,
Heidi Tiller,
Maria Averina,
Gøril Heide,
Mette Kjær Killie,
Cedric Ghevaert
m.fl.:
Characterization of a human platelet antigen-1a-specific monoclonal antibody derived from a B cell from a woman alloimmunized in pregnancy
Issaka Yougbaré,
Sean Lang,
Hong Yang,
Pingguo Chen,
Xu Zhao,
Wei-She Tai
m.fl.:
Maternal anti-platelet β3 integrins impair angiogenesis and cause intracranial hemorrhage
Journal of Clinical Investigation 2015 DOI
Rick Kapur,
Iwan Kustiawan,
Anne Cathrine Vestrheim,
Carolien A. M. Koeleman,
Remco Visser,
Helga Einarsdottir
m.fl.:
A prominent lack of IgG1-Fc fucosylation of platelet alloantibodies in pregnancy
Blood 2014 DOI
Maria Therese Ahlen,
Anne Husebekk,
Mette Kjær Killie,
Jens Kjeldsen-Kragh,
Martin L. Olsson,
Bjørn Ragnar Skogen
:
The Development of Severe Neonatal Alloimmune Thrombocytopenia due to Anti-HPA-1a Antibodies Is Correlated to Maternal ABO Genotypes
Heidi Tiller,
Mette Kjær Killie,
Anne Husebekk,
Bjørn Ragnar Skogen,
Heyu Ni,
Jens Kjeldsen-Kragh
m.fl.:
Platelet antibodies and fetal growth: maternal antibodies against fetal platelet antigen 1a are strongly associated with reduced birthweight in boys
Acta Obstetricia et Gynecologica Scandinavica 2012 DOI
Heidi Tiller,
Mette Kjær Killie,
Pingguo Chen,
Mariana Eksteen,
Anne Husebekk,
Bjørn Ragnar Skogen
m.fl.:
Toward a prophylaxis against fetal and neonatal alloimmune thrombocytopenia: induction of antibody-mediated immune suppression and prevention of severe clinical complications in a murine model
Transfusion 2012 DOI
Anne Husebekk,
M El Ekiaby,
G Gorgy,
Mette Kjær Killie,
Camilla Uhlin Hansen,
Wahida Salma
m.fl.:
Foetal/neonatal alloimmune thrombocytopenia in Egypt; human platelet antigen genotype frequencies and antibody detection and follow-up in pregnancies
Transfusion and Apheresis Science 2012 DOI
Bjørn Ragnar Skogen,
Mette Kjær Killie,
Jens Kjeldsen-Kragh,
Maria Therese Ahlen,
Heidi Tiller,
Tor Brynjar Stuge
m.fl.:
Reconsidering fetal and neonatal alloimmune thrombocytopenia with a focus on screening and prevention
Expert Review of Hematology 2010 DOI
Mette Kjær Killie,
Wahida Salma,
eirin listau Bertelsen,
Bjørn Ragnar Skogen,
Anne Husebekk
:
Quantitative MAIPA: Comparison of different MAIPA protocols
Transfusion and Apheresis Science 2010 DOI
Anne Husebekk,
Maria Therese Ahlen,
Mette Kjær Killie,
Heidi Tiller,
Mariana Eksteen,
Ida Løken Killie
m.fl.:
Blood group antigens and immune responses-detailed knowledge is necessary to prevent immunization and to follow up immunized individuals
ISBT Science Series 2010
Bjørn Ragnar Skogen,
Anne Husebekk,
Mette Kjær Killie,
J Kjeldsen-Kragh
:
Neonatal Alloimmune Thrombocytopenia is Not What It was A Lesson Learned from a Large Prospective Screening and Intervention Program
Scandinavian Journal of Immunology 2009 DOI
Anne Husebekk,
Mette Kjær Killie,
Jens Kjeldsen-Kragh,
Bjørn Ragnar Skogen
:
Is it time to implement HPA-1 screening in pregnancy?
Current opinion in hematology 2009 DOI
Heidi Tiller,
Mette Kjær Killie,
Bjørn Ragnar Skogen,
Pål Øian,
Anne Husebekk
:
Neonatal alloimmune thrombocytopenia in Norway: poor detection rate with nonscreening versus a general screening programme
BJOG: An International Journal of Obstetrics and Gynaecology 2009 DOI
Maria Therese Ahlen,
Anne Husebekk,
Mette Kjær Killie,
Bjørn Ragnar Skogen,
Tor Brynjar Stuge
:
T-cell responses associated with neonatal alloimmune thrombocytopenia: isolation of HPA-1a-specific, HLA-DRB3*0101-restricted CD4+ T cells
Blood 2009 DOI
Maria Averina,
Sandra Huber,
Jan Brox,
Mette Kjær,
Bjørn Bolann
:
Lead, mercury, polychlorinated biphenyls (PCBs) and per- and polyfluoroalkyl substances (PFAS) in blood donors - The multicenter Norwegian donor study
2024
Maria Averina,
Sandra Huber,
Jan Brox,
Mette Kjær,
Bjørn Bolann
:
Lead, mercury, polychlorinated biphenyls (PCBs) and per- and polyfluoroalkyl substances (PFAS) in blood donors - The multicenter Norwegian donor study
2024
Mette Kjær
:
What is the true story of FNAIT-induced complications?
The Lancet Haematology 2023 DOI
Maria Averina,
Sandra Huber,
Jan Brox,
Mette Kjær,
Bjørn Bolann
:
Environmental pollutants in blood donors - The multicenter Norwegian donor study
2023
Heidi Tiller,
Mette Kjær,
Maria Therese Ahlen,
Jens Kjeldsen-Kragh
:
Føtal/neonatal alloimmun trombocytopeni (FNAIT) - hvordan redusere risiko for intrakraniell blødning hos foster/ nyfødt - erfaringer fra Norge
Bestpractice Onkologi/Hematologi 2019
Mette Kjær,
Jens Kjeldsen-Kragh,
Cathrine Fiskum,
Irene Leinan,
Bjørn Skogen,
Anne Husebekk
:
Screening for fetal and neonatal alloimmune thrombocytopenia ? lessons learned from a Norwegian screening program
Acta Obstetricia et Gynecologica Scandinavica 2018 DOI
Sandra Huber,
Maria Averina,
Inger Njølstad,
Anne-Sofie Furberg,
Bjørn Johan Bolann,
Mette Kjær
m.fl.:
Perfluoroalkyl substances in different cohorts from North Norway
2017
Heidi Tiller,
Mette Kjær Killie,
Anne Husebekk,
Bjørn Ragnar Skogen,
Jens Kjeldsen-Kragh
:
The natural course of HPA-1a-immunized subsequent pregnancies and clinical outcome of neonates
American Journal of Obstetrics and Gynecology 2014
Mariana Eksteen,
Mette Kjær Killie,
Anne Husebekk,
Bjørn Ragnar Skogen,
Tor Brynjar Stuge
:
A NOVEL HUMAN MONOCLONAL HPA-1A-SPECIFIC ANTIBODY IS A USEFUL TOOL FOR DIAGNOSTICS IN FETAL AND NEONATAL ALLOIMMUNE THROMBOCYTOPENIA
Vox Sanguinis 2013
R Kapur,
Arne Vestrheim,
C Koeleman,
L Porcelijn,
D. Jackson,
B Kumpel
m.fl.:
A PROMINENT LACK OF IGG1 FC-FUCOSYLATION OF PLATELET-ALLOANTIBODIES IN PREGNANCY
Vox Sanguinis 2013
G Bertrand,
T. Bakchoul,
K. Javela,
Mette Kjær Killie,
C Kaplan
:
Interlaboratory workshop on anti-HPA-1a alloantibody quantification with the mAb-specific immobilization of platelet antigen technique
Journal of Thrombosis and Haemostasis 2012 DOI
Anne Husebekk,
Heidi Tiller,
Mette Kjær Killie,
Mariana Eksteen,
Maria Therese Ahlen,
Tor Brynjar Stuge
m.fl.:
TOWARDS A PROPHYLACTIC TREATMENT OF HPA-1A-RELATED FETAL AND NEONATAL ALLOIMMUNE THROMBOCYTOPENIA (FNAIT)
Vox Sanguinis 2012
Anne Husebekk,
Maria Therese Ahlen,
Mette Kjær Killie,
Heidi Tiller,
Mariana Eksteen,
Ida Løken Killie
m.fl.:
MATERNAL ALLOIMMUNE RESPONSE DURING PREGNANCY: BRAKE OF MATERNAL TOLERANCE TO FETAL HUMAN PLATELET ANTIGEN 1A ANTIGEN MAY BE ASSOCIATED WITH REDUCED PLACENTAL FUNCTION
Placenta 2011
Jens Kjeldsen-Kragh,
Anne Husebekk,
Mette Kjær Killie,
Bjørn Ragnar Skogen
:
The pathophysiology of FNAIT cannot be deduced from highly selected retrospective data
Blood 2011 DOI
Heidi Tiller,
Pingguo Chen,
Bjørn Ragnar Skogen,
Mette Kjær Killie,
Anne Husebekk,
Mariana Eksteen
m.fl.:
Administration of Anti-Platelet Antibodies Prevents the Anti-Platelet Immune Response and Bleeding Complications of Neonatal Immune Thrombocytopenia in a Murine Model
Blood 2009
Heidi Tiller,
Mette Kjær Killie,
Anne Husebekk,
Bjørn Ragnar Skogen,
Heyu Ni,
Jens Kjeldsen-Kragh
m.fl.:
Association Between Maternal Anti-HPA1a Antibodies and Birth Weight of the Newborn
Blood 2009
J Kjeldsen-Kragh,
Michael Kim,
Mette Kjær Killie,
Anne Husebekk,
J Freedman,
John W Semple
:
In HPA 1a-immunized women the decrease in anti-HPA 1a antibody level during pregnancy is not associated with anti-idiotypic antibodies
Anne Husebekk,
Mette Kjær Killie,
T Stuge,
Heidi Tiller,
MT Ahlen,
Jens Kjeldsen-Kragh
m.fl.:
The knowledge of the pathophysiology of fetal/neonatal alloimmune thrombocytopenia is of importance to prevent immunization and to handle the immunized pregnancies in order to prevent hemorrhage
Vox Sanguinis 2008
Mette Kjær Killie,
Jens Kjeldsen-Kragh,
Anne Husebekk,
Bjørn Ragnar Skogen,
Jan Abel Olsen,
ivar sØnbØ Kristiansen
:
Cost-effectiveness of screening for neonatal alloimmune thrombocytopenia was based on invalid assumption. Authors Reply
BJOG: An International Journal of Obstetrics and Gynaecology 2008
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