Lars Uhlin-Hansen
Stillingsbeskrivelse
Lars Uhlin-Hansen er professor i rettsmedisin og patologi.
Anna Maria Wirsing,
Inger-Heidi Bjerkli,
Sonja Eriksson Steigen,
Oddveig G Rikardsen,
Synnøve Norvoll Magnussen,
Beate Hegge
m.fl.:
Validation of Selected Head and Neck Cancer Prognostic Markers from the Pathology Atlas in an Oral Tongue Cancer Cohort
Sonja Eriksson Steigen,
Tine Merete Søland,
Elisabeth Sivy Nginamau,
Helene Laurvik,
Daniela Elena Costea,
Anne Christine Johannessen
m.fl.:
Grading of oral squamous cell carcinomas – Intra and interrater agreeability: Simpler is better?
Inger-Heidi Bjerkli,
Olav Jetlund,
Gunnhild Karevold,
Åsa Karlsdottir,
Ellen A. Andreassen Jaatun,
Lars Uhlin-Hansen
m.fl.:
Characteristics and prognosis of primary treatment-naïve oral cavity squamous cell carcinoma in Norway, a descriptive retrospective study
Sushma Pandey,
Tarig Al-Hadi Osman,
Sunita Sharma,
Evan Michael Vallenari,
Aboulghassem Shahdafar,
Chin B. Pun
m.fl.:
Loss of S100A14 expression at the tumor-invading front correlates with poor differentiation and worse prognosis in oral squamous cell carcinoma
Inger-Heidi Bjerkli,
Elin Synnøve Hadler-Olsen,
Elisabeth Sivy Nginamau,
Helene Laurvik,
Tine Merete Søland,
Daniela Elena Costea
m.fl.:
A combined histo-score based on tumor differentiation and lymphocytic infiltrate is a robust prognostic marker for mobile tongue cancer
Inger-Heidi Bjerkli,
Helene Laurvik,
Elisabeth Sivy Nginamau,
Tine Merete Søland,
Daniela Elena Costea,
Håkon Hov
m.fl.:
Tumor budding score predicts lymph node status in oral tongue squamous cell carcinoma and should be included in the pathology report
Anna Maria Wirsing,
Ida Korsnes Ervik,
Marit Seppola,
Lars Uhlin-Hansen,
Sonja Eriksson Steigen,
Elin Synnøve Hadler-Olsen
:
Presence of high-endothelial venules correlates with a favorable immune microenvironment in oral squamous cell carcinoma
Synnøve Magnussen,
Elin Synnøve Hadler-Olsen,
Daniela Elena Costea,
Eli Berg,
Cristiane de Albuquerque Cavalcanti Jacobsen,
Bente Mortensen
m.fl.:
Cleavage of the urokinase receptor (uPAR) on oral cancer cells: Regulation by transforming growth factor - beta1 (TGF-beta1) and potential effects on migration and invasion
Eystein Skjölsvik,
Tor Steensrud,
Øystein Dahl-Eriksen,
Lars Uhlin-Hansen,
Per Lunde
:
Cardiac Perforation Caused by Cement Embolus After Total Hip Replacement
Circulation 2015 DOI
Elin Synnøve Hadler-Olsen,
Ann Iren Solli,
Anne Dragøy Hafstad,
Jan-Olof Winberg,
Lars Uhlin-Hansen
:
Intracellular MMP-2 Activity in Skeletal Muscle is Associated with Type II Fibers
Oddveig G Rikardsen,
Synnøve Magnussen,
Gunbjørg Svineng,
Elin Synnøve Hadler-Olsen,
Lars Uhlin-Hansen,
Sonja Eriksson Steigen
:
Plectin as a prognostic marker in non-metastatic oral squamous cell carcinoma
Emma Pirilä,
Otto Väyrynen,
Elias Sundquist,
Kaisa Päkkilä,
Pia Nyberg,
Sini Nurmenniemi
m.fl.:
Macrophages modulate migration and invasion of human tongue squamous cell carcinoma
Anna Maria Wirsing,
Oddveig G Rikardsen,
Sonja Eriksson Steigen,
Lars Uhlin-Hansen,
Elin Synnøve Hadler-Olsen
:
Presence of tumour high-endothelial venules is an independent positive prognostic factor and stratifies patients with advanced-stage oral squamous cell carcinoma
Synnøve Magnussen,
Oddveig G Rikardsen,
Elin Synnøve Hadler-Olsen,
Lars Uhlin-Hansen,
Sonja Eriksson Steigen,
Gunbjørg Svineng
:
Urokinase Plasminogen Activator Receptor (uPAR) and Plasminogen Activator Inhibitor-1 (PAI-1) are potential predictive biomarkers in early stage Oral Squamous Cell Carcinomas (OSCC)
Anna Wirsing,
Oddveig G Rikardsen,
Sonja Eriksson Steigen,
Lars Uhlin-Hansen,
Elin Synnøve Hadler-Olsen
:
Characterisation and prognostic value of tertiary lymphoid structures in oral squamous cell carcinoma
Oddveig G Rikardsen,
Inger-Heidi Bjerkli,
Lars Uhlin-Hansen,
Elin Synnøve Hadler-Olsen,
Sonja Eriksson Steigen
:
Clinicopathological characteristics of oral squamous cell carcinoma in Northern Norway: a retrospective study
Synnøve Magnussen,
Elin Synnøve Hadler-Olsen,
Nadezhda Latysheva,
Emma Pirila,
Sonja Eriksson Steigen,
Robert Hanes
m.fl.:
Tumour Microenvironments Induce Expression of Urokinase Plasminogen Activator Receptor (uPAR) and Concomitant Activation of Gelatinolytic Enzymes
Nabin Malla,
Eli Berg,
Achilleas D. Theocharis,
Gunbjørg Svineng,
Lars Uhlin-Hansen,
Jan-Olof Winberg
:
Invitro reconstitution of complexes between pro-matrix metalloproteinase-9 and the proteoglycans serglycin and versican
The FEBS Journal 2013 DOI
Ann Iren Solli,
Bodil Irene Fadnes,
Jan-Olof Winberg,
Lars Uhlin-Hansen,
Elin Synnøve Hadler-Olsen
:
Tissue- and Cell-Specific Co-localization of Intracellular Gelatinolytic Activity and Matrix Metalloproteinase 2
Journal of Histochemistry and Cytochemistry 2013 DOI
Elin Synnøve Hadler-Olsen,
Jan-Olof Winberg,
Lars Uhlin-Hansen
:
Matrix metalloproteinases in cancer: their value as diagnostic and prognostic markers and therapeutic targets
Tumour Biology 01. august 2013 DOI
Bodil Irene Fadnes,
Elin Synnøve Hadler-Olsen,
Ingebrigt Sylte,
Lars Uhlin-Hansen,
Jan-Olof Winberg
:
Matrix metalloproteinase complexes and their biological significance
Walter de Gruyter (De Gruyter) 2012 DOI
Bodil Irene Fadnes,
Anne Husebekk,
Gunbjørg Svineng,
Øystein Rekdal,
Masaki Yanagishita,
Svein Olav Kolset
m.fl.:
The proteoglycan repertoire of lymphoid cells
Elin Synnøve Hadler-Olsen,
Hilde Ljones,
Chandra Sekhar Ravuri,
Ahmad Omair,
Oddveig G Rikardsen,
Gunbjørg Svineng
m.fl.:
Organ specific regulation of tumour invasiveness and gelatinolytic activity at the invasive front
European Journal of Cancer 2011 DOI
Elin Synnøve Hadler-Olsen,
Bodil Irene Fadnes,
Ingebrigt Sylte,
Lars Uhlin-Hansen,
Jan-Olof Winberg
:
Regulation of matrix metalloproteinase activity in health and disease
The FEBS Journal 2011 DOI
Nabin Malla,
Eli Berg,
Ugo Moens,
Lars Uhlin-Hansen,
Jan-Olof Winberg
:
Biosynthesis of Promatrix Metalloproteinase-9/Chondroitin Sulphate Proteoglycan Heteromer Involves a Rottlerin-Sensitive Pathway
Hilde Ljones,
Elin Synnøve Hadler-Olsen,
Synnøve Magnussen,
Oddveig G Rikardsen,
sonja eriksson Steigen,
elisabeth Sundkvist
m.fl.:
S100A4 Expression in Xenograft Tumors of human carcinoma cell lines is induced by the tumor microenvironment
American Journal of Pathology 2011 DOI
Bodil Irene Fadnes,
Lars Uhlin-Hansen,
Inger Lindin,
Øystein Rekdal
:
Small lytic peptides escape the inhibitory effect of heparan sulfate on the surface of cancer cells
Elin Synnøve Hadler-Olsen,
Jan-Olof Winberg,
Finn P. Reinholt,
Terje Larsen,
Lars Uhlin-Hansen,
Trond Geir Jenssen
m.fl.:
Proteases in plasma and kidney of db /db mice as markers of diabetes-induced nephropathy
Elin Synnøve Hadler-Olsen,
Hilde Ljones,
Oddveig G Rikardsen,
Sonja Eriksson Steigen,
Premasany Kanapathippillai,
Reidar Grenman
m.fl.:
Stromal impact on tumor growth and lymphangiogenesis in human carcinoma xenografts
Elin Synnøve Hadler-Olsen,
Premasany Kanapathippillai,
Eli Berg,
Gunbjørg Svineng,
Jan-Olof Winberg,
Lars Uhlin-Hansen
:
Gelatin In Situ Zymography on Fixed, Paraffin-embedded Tissue: Zinc and Ethanol Fixation Preserve Enzyme Activity
Journal of Histochemistry and Cytochemistry 2010 DOI
Bodil Irene Fadnes,
Øystein Rekdal,
lars Uhlin-hansen
:
The anticancer activity of lytic peptides is inhibited by heparan sulfate on the surface of the tumor cells
BMC Cancer 2009 DOI
Nabin Malla,
Stian Sjøli,
Jan-Olof Winberg,
Elin Synnøve Hadler-Olsen,
lars Uhlin-hansen
:
Biological and pathobiological functions of gelatinase dimers and complexes
Connective Tissue Research 2008 DOI
Nabin Malla,
Eli Berg,
lars Uhlin-hansen,
Jan-Olof Winberg
:
Interaction of pro-matrix metalloproteinase-9/proteoglycan heteromer with gelatin and collagen
Journal of Biological Chemistry 2008 DOI
Berit Hansen,
Inger Øynebråten,
Lars Uhlin-Hansen,
Bård Smedsrød
:
Endocytosis and degradation of serglycin in liver sinusoidal endothelial cells
Molecular and Cellular Biochemistry 2006
Lars Uhlin Hansen
:
Retinal hemorrhages in an infant with cerebral edema and asphyxia after prolonged cardiopulmonary resuscitation: a case report.
2024
Katrine Holter,
Henriette Willix,
Lars Uhlin-Hansen
:
Rett og Slett #50: Filleristing: En ny justisskandale?
22. februar 2023 DATA
Lars Uhlin-Hansen
:
Ny utgave av lærebok i rettsmedisin
Tidsskrift for Den norske legeforening 2021 DOI
Sushma Pandey Dhakal,
Tarig A. Osman,
Sunita Sharma,
Lars Uhlin-Hansen,
Chin Babadur Pun,
Dej K. Gautam
m.fl.:
Oral squamous cell carcinomas expressing higher levels of S100A14 correlate with prognosis
2019
Sonja Eriksson Steigen,
Anna Maria Wirsing,
Elin Synnøve Hadler-Olsen,
Lars Uhlin-Hansen,
Marit Seppola,
Ida Korsnes Ervik
:
Oral cancer and high endothelial venules (HEV)
2017
Anna Wirsing,
Oddveig G Rikardsen,
Sonja Eriksson Steigen,
Lars Uhlin-Hansen,
Elin Synnøve Hadler-Olsen
:
Prognostic relevance of tertiary lymphoid structures in oral squamous cell carcinoma
2014 ARKIV
Anna Wirsing,
Elin Synnøve Hadler-Olsen,
Oddveig G Rikardsen,
Lars Uhlin-Hansen
:
Tertiary lymphoid organs in oral squamous cell carcinoma
2013
Ann Iren Solli,
Bodil Irene Fadnes,
Jan-Olof Winberg,
Lars Uhlin-Hansen,
Elin Synnøve Hadler-Olsen
:
Intracellular MMP-2 localization and activity
2013
Gunbjørg Svineng,
Synnøve Magnussen,
Elin Synnøve Hadler-Olsen,
Nadezhda Latysheva,
Emma Pirila,
Sonja Eriksson Steigen
m.fl.:
Stromal induced expression of uPAR
2013
Elin Synnøve Hadler-Olsen,
Ann Iren Solli,
Anne Dragøy Hafstad,
Jan-Olof Winberg,
Lars Uhlin-Hansen
:
Intracellular MMP-2 Activity in Skeletal Muscle is Associated with Type II Fibers
2013
Berit Myhre Dupuy,
Dorota Perchla,
Gunnar Markussen,
Torleiv Ole Rognum,
Lars Uhlin-Hansen,
Ivar Skjåk Nordrum
m.fl.:
DNA-analysis for DVI or other identification purposes. Evaluation of the COPAN 4N6FLOQSwabs™ for collection of blood or tissue samples from deceased individuals
2012
Arne Stray-Pedersen,
Sidsel Rogde,
Kari Ormstad,
Åshild Vege,
Gerd Jorunn Delavaris,
Marianne Skjerven-Martinsen
m.fl.:
Forensic medical examination after the July 22nd 2011 terror attack
2012
Elin Synnøve Hadler-Olsen,
Ann Iren Solli,
Bodil Irene Fadnes,
Lars Uhlin-Hansen,
Jan-Olof Winberg
:
Tissue localization of intracellular gelatinolytic activity
The FEBS Journal 2012
Elin Synnøve Hadler-Olsen,
Chandra Sekhar Ravuri,
Hilde Ljones Wetting,
Oddveig G Rikardsen,
sonja eriksson Steigen,
Gunbjørg Svineng
m.fl.:
Stromal Impact on Tumor Invasiveness and Gelatinolytic Activity at the Invasive Front
2011
Elin Synnøve Hadler-Olsen,
Hilde Ljones,
O Rikardsen,
sonja eriksson Steigen,
Jan-Olof Winberg,
Gunbjørg Svineng
m.fl.:
Stromal impact on tumor growth and lymphangiogenesis in human carcinoma xenografts
APMIS - Journal of Pathologiy, Microbiology and Immunology 2010
Elin Synnøve Hadler-Olsen,
Chandra Sekhar Ravuri,
Hilde Ljones,
Oddveig G Rikardsen,
sonja eriksson Steigen,
Gunbjørg Svineng
m.fl.:
Organ specific stromal influence on tumor invasiveness and proteolytic activity at the invasive front
European Journal of Cancer 2010 DOI
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Forskningsinteresser
Kreft, med hovedfokus på munnhulekreft.
Undervisning
Underviser i anatomi, patologi og rettsmedisin.
Medlem i forskningsgruppe
Medlem i prosjekt
CV
Lars Uhlin-Hansen er professor i rettsmedisin og patologi. Han har bred rettsmedisinsk erfaring fra inn- og utland, og har i over 20 år regelmessig blitt benyttet som rettsmedisinsk sakkyndig i straffesaker i hele landet. Han har også hatt oppdrag for Den internasjonale straffedomstolen i Haag. Han er medlem av den nasjonale ID-gruppen og har deltatt i en rekke operasjoner nasjonalt og internasjonalt. Han er medlem av Den rettsmedisinske kommisjon, og er leder for Rettsgenetisk senter ved UiT. Hans forskningsaktivitet har i hovedsak vært kreftrelatert og de siste årene har han spesielt fokusert på munnhulekreft. Han er leder for Norwegian Oral Cancer (NOROC) studien, en tverrfaglig studie på munnhulekreft hvor alle universitetssykehusene i Norge er involvert. Uhlin-Hansen har bistilling som overlege på avdeling for Klinisk patologi, Universitetssykehuset Nord-Norge hvor han blant annet har et ansvar for diagnostikk av lymfeknutekreft (lymfom).
Utdanning
1982: Cand.med. (MD), Universitetet i Tromsø
1990: Dr. med. (PhD), Universitetet i Tromsø
2003: Spesialist i patologi.
Yrkespraksis
1985-1987: Stipendiat, Institutt for medisinsk biologi, UiT
1987-2006: Amanuensis/førsteamanuensis, Institutt for medisinsk biologi
1991-1992: Visiting scientist, National Institutes of Health, Bethesda, USA
1996-2001: Assistentlege, Patologisk anatomisk avdeling, UNN
1997-1998: Visiting scientist, US Food and Drug Administration, Bethesda, USA
2001-d.d.: Overlege, Patologisk anatomisk avdeling/Klinisk patologi, UNN
2003: Visiting pathologist, Hotel Dieu, Paris
2004: Visiting pathologist, Medical examiners department, Miami
2006-d.d.: Professor i rettsmedisin og patologi, Institutt for medisinsk biologi, UiT
2010-2011: Visiting scientist, Retsmedicinsk institut, Københavns universitet1