Bilde av Kristiansen, Kurt
Bilde av Kristiansen, Kurt
Eksperimentell og klinisk farmakologi kurt.kristiansen@uit.no +4777644875 47848742 Her finner du meg

Kurt Kristiansen


Førsteamanuensis, fagenhetsleder


  • Ingebrigt Sylte, Mari Gabrielsen, kurt Kristiansen :
    Homology Modeling of Transporter Proteins
    Methods in molecular biology 2023 ARKIV / DOI
  • Åse-Karen Mortensen, Silje Mæhre, kurt Kristiansen, Eldbjørg Sofie Heimstad, Geir W. Gabrielsen, Bjørn Munro Jenssen m.fl.:
    Homology modeling to screen for potential binding of contaminants to thyroid hormone receptor and transthyretin in glaucous gull (Larus hyperboreus) and herring gull (Larus argentatus)
    Computational Toxicology 2020 ARKIV / DOI
  • Linn M Evenseth, Kurt Kristiansen, You Song, Knut Erik Tollefsen, Ingebrigt Sylte :
    In silico site-directed mutagenesis of the Daphnia magna ecdysone receptor identifies critical amino acids for species-specific and inter-species differences in agonist binding
    Computational Toxicology 2019 ARKIV / DOI
  • Jon A. Doering, Sehan Lee, kurt Kristiansen, Linn Evenseth, Ingebrigt Sylte, Mace G. Barron m.fl.:
    In silico site-directed mutagenesis informs species-specific predictions of chemical susceptibility derived from the Sequence Alignment to Predict Across Species Susceptibility (SeqAPASS) tool
    Toxicological Sciences 2018 DOI
  • Dawid Warszycki, Manuel Rueda, Stefan Mordalski, kurt Kristiansen, Grzegorz Satala, Krzysztof Rataj m.fl.:
    From Homology Models to a Set of Predictive Binding Pockets-a 5-HT<sub>1A</sub> Receptor Case Study
    Journal of Chemical Information and Computer Sciences 2017 DOI
  • Heli Anna Irmeli Routti, Roger Lille-Langøy, Mari Katrine Berg, Trine Fink, Mikael Harju, Kurt Kristiansen m.fl.:
    Environmental chemicals modulate polar bear (Ursus maritimus) Peroxisome Proliferator-Activated Receptor Gamma (PPARG) and adipogenesis in vitro
    Environmental Science and Technology 2016 DOI
  • Mari Gabrielsen, Rafal Kurczab, Agata Siwek, Malgorzata Wolak, Aina Westrheim Ravna, kurt Kristiansen m.fl.:
    Identification of novel serotonin transporter compounds by virtual Screening
    Journal of Chemical Information and Modeling 2014 ARKIV / DOI
  • Irina Kufareva, Vsevolod Katritch, Thibaud Freyd, Mari Gabrielsen, kurt Kristiansen, Ingebrigt Sylte m.fl.:
    Advances in GPCR modeling evaluated by the GPCR Dock 2013 assessment: Meeting new challenges
    Structure 2014 DOI
  • Dawid Warszycki, Stefan Mordalski, kurt Kristiansen, Rafal Kafel, Ingebrigt Sylte, Zdzislaw Chilmonczyk m.fl.:
    A Linear Combination of Pharmacophore Hypotheses as a New Tool in Search of New Active Compounds - An Application for 5-HT1A Receptor Ligands
    PLOS ONE 2013 ARKIV / DOI
  • Anett Kristin Larsen, kurt Kristiansen, Ingebrigt Sylte, Ole Morten Seternes, Berit Bang :
    Differences in PAR-2 activating potential by king crab (Paralithodes camtschaticus), salmon (Salmo salar), and bovine (Bos taurus) trypsin
    BMC Research Notes 2013 ARKIV / DOI
  • Mari Gabrielsen, aina westrheim Ravna, kurt Kristiansen, Ingebrigt Sylte :
    Substrate binding and translocation of the serotonin transporter studied by docking and molecular dynamics simulations
    Journal of Molecular Modeling 2012 ARKIV / DOI
  • Stefan Mordalski, Tomasz Kosciolek, kurt Kristiansen, Ingebrigt Sylte, Andrezej J Bojarski :
    Protein binding site analysis by means of structural interaction fingerprint patterns
    Bioorganic & Medicinal Chemistry Letters 2011 DOI
  • Malgorzata Jaronczyk, Zdizlav Chilmonczyk, AP Mazurek, Gabriel Nowak, aina westrheim Ravna, kurt Kristiansen m.fl.:
    The molecular interactions of buspirone analogues with the serotonin transporter
    Bioorganic & Medicinal Chemistry 2008 DOI
  • Aina Westrheim Ravna, Ingebrigt Sylte, Kurt Kristiansen, Svein G. Dahl :
    Putative drug binding conformations of monoamine transporters
    Bioorganic & Medicinal Chemistry 2006
  • J.D. Paasche, T. Attramadal, Kurt Kristiansen, M.P. Oksvold, H.K. Johansen, H.S. Huitfeldt m.fl.:
    Subtype-specific sorting of the ETA endothelin receptor by a novel endocytic recycling signal for G protein-coupled receptors
    Molecular Pharmacology 2005
  • HK Knutsen, HB Ølstørn, JE Paulsen, T Husøy, Ingeborg Løstegaard Goverud, Else Marit Løberg m.fl.:
    Increased levels of PPARbeta/delta and cylin D1 in flat dysplastic ACF and adenomas in Apc(Min/+) mice
    Anticancer Research 2005
  • Jack-Ansgar Bruun, Ernst I.s. Thomassen, Kurt Kristiansen, Garth Daryl Tylden, Turid Holm, Ingvild Mikkola m.fl.:
    The third helix of the homeodomain of paired class homeodomain proteins acts as a recognition helix both for DNA and protein interactions
    Nucleic Acids Research (NAR) 2005 ARKIV
  • Kurt Kristiansen :
    Molecular mechanisms of ligand binding, signaling, and regulation within the superfamily of G-protein-coupled receptors: molecular modeling and mutagenesis approaches to receptor structure and function
    Pharmacology and Therapeutics 2004
  • Trond Lamark, maria Perander, Heidi Outzen, kurt Kristiansen, Aud Karin Øvervatn, Espen Michaelsen m.fl.:
    Interaction codes within the family of mammalian Phox and Bem1p domain-containing proteins.
    Journal of Biological Chemistry 2003 FULLTEKST / DOI
  • Kaare Magne Nielsen, Kurt Kristiansen :
    Gene conversion as a source of nucleotide diversity in Plasmodium falciparum
    Molecular Biology and Evolution (MBE) 2003
  • Rasmus K. Petersen, RK Petersen, Claus Jørgensen, C Jorgensen, Arild C. Rustan, Livar Frøyland m.fl.:
    Arachidonic acid-dependent inhibition of adipocyte differentiation requires PKA activity and is associated with sustained expression of cyclooxygenases
    Journal of Lipid Research 2003
  • Malgorzata Jaronczyk, Zdizlav Chilmonczyk, AP Mazurek, M Dybala, aina westrheim Ravna, kurt Kristiansen m.fl.:
    Molecular mechanism of selective serotonin reuptake inhibitors (SSRI's) interactions with serotonin transporter
    Journal of Peptide Science 2006
  • Olayiwola Adedotun Adekoya, Svein G. Dahl, Mari Gabrielsen, Osman A.B.S.M. Gani, Mahmud Tareq Hassan Khan, kurt Kristiansen m.fl.:
    The molecular modelling group
    2006
  • Malgorzata Jaronczyk, Zdizlav Chilmonczyk, AP Mazurek, M Dybala, aina westrheim Ravna, kurt Kristiansen m.fl.:
    Molecular mechanism of selective serotonin reuptake inhibitors (SSRI's)interactions with serotonin transporter
    2006
  • J.D. Paasche, T. Attramadal, Kurt Kristiansen, H.K. Johansen, Svein G. Dahl, Håvard Attramadal :
    Structural characterization of a motif that dictates recycling of the ETA receptor via a novel molecular mechanism
    Circulation 2003

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    Forskningsinteresser

    Struktur og funksjon av G-proteinkoblede reseptorer
    Studier av legemidler og deres interaksjoner med membranproteiner.




    CV

    Utdanning

    1992    Cand. Scient., University of Tromsø
    1997     Dr. Scient., University of Tromsø

    Yrkespraksis

    1997-1998    Postdoctoral fellowship, Case Western University, Cleveland, Ohio, U.S.
    1998-1999    Postdoctoral fellowship from Forskerakademiet in Denmark, Danish University of Pharmaceutical Sciences, Copenhagen, Denmark
    1999-2000    Postdoctoral fellowship, Institute of Medical Pharmacology, Berlin, Germany
    2000-2006    Postdoctoral fellowship, Research council of Norway and Functional Genomics in northern Norway, University of Tromsø
    2006-Present  Associate Professor in Pharmacology, University of Tromsø