Kurt Kristiansen
Ingebrigt Sylte,
Mari Gabrielsen,
kurt Kristiansen
:
Homology Modeling of Transporter Proteins
Åse-Karen Mortensen,
Silje Mæhre,
kurt Kristiansen,
Eldbjørg Sofie Heimstad,
Geir W. Gabrielsen,
Bjørn Munro Jenssen
m.fl.:
Homology modeling to screen for potential binding of contaminants to thyroid hormone receptor and transthyretin in glaucous gull (Larus hyperboreus) and herring gull (Larus argentatus)
Linn M Evenseth,
Kurt Kristiansen,
You Song,
Knut Erik Tollefsen,
Ingebrigt Sylte
:
In silico site-directed mutagenesis of the Daphnia magna ecdysone receptor identifies critical amino acids for species-specific and inter-species differences in agonist binding
Jon A. Doering,
Sehan Lee,
kurt Kristiansen,
Linn Evenseth,
Ingebrigt Sylte,
Mace G. Barron
m.fl.:
In silico site-directed mutagenesis informs species-specific predictions of chemical susceptibility derived from the Sequence Alignment to Predict Across Species Susceptibility (SeqAPASS) tool
Toxicological Sciences 2018 DOI
Dawid Warszycki,
Manuel Rueda,
Stefan Mordalski,
kurt Kristiansen,
Grzegorz Satala,
Krzysztof Rataj
m.fl.:
From Homology Models to a Set of Predictive Binding Pockets-a 5-HT<sub>1A</sub> Receptor Case Study
Journal of Chemical Information and Computer Sciences 2017 DOI
Heli Anna Irmeli Routti,
Roger Lille-Langøy,
Mari Katrine Berg,
Trine Fink,
Mikael Harju,
Kurt Kristiansen
m.fl.:
Environmental chemicals modulate polar bear (Ursus maritimus) Peroxisome Proliferator-Activated Receptor Gamma (PPARG) and adipogenesis in vitro
Environmental Science and Technology 2016 DOI
Mari Gabrielsen,
Rafal Kurczab,
Agata Siwek,
Malgorzata Wolak,
Aina Westrheim Ravna,
kurt Kristiansen
m.fl.:
Identification of novel serotonin transporter compounds by virtual Screening
Irina Kufareva,
Vsevolod Katritch,
Thibaud Freyd,
Mari Gabrielsen,
kurt Kristiansen,
Ingebrigt Sylte
m.fl.:
Advances in GPCR modeling evaluated by the GPCR Dock 2013 assessment: Meeting new challenges
Structure 2014 DOI
Dawid Warszycki,
Stefan Mordalski,
kurt Kristiansen,
Rafal Kafel,
Ingebrigt Sylte,
Zdzislaw Chilmonczyk
m.fl.:
A Linear Combination of Pharmacophore Hypotheses as a New Tool in Search of New Active Compounds - An Application for 5-HT1A Receptor Ligands
Anett Kristin Larsen,
kurt Kristiansen,
Ingebrigt Sylte,
Ole Morten Seternes,
Berit Bang
:
Differences in PAR-2 activating potential by king crab (Paralithodes camtschaticus), salmon (Salmo salar), and bovine (Bos taurus) trypsin
Mari Gabrielsen,
aina westrheim Ravna,
kurt Kristiansen,
Ingebrigt Sylte
:
Substrate binding and translocation of the serotonin transporter studied by docking and molecular dynamics simulations
Stefan Mordalski,
Tomasz Kosciolek,
kurt Kristiansen,
Ingebrigt Sylte,
Andrezej J Bojarski
:
Protein binding site analysis by means of structural interaction fingerprint patterns
Bioorganic & Medicinal Chemistry Letters 2011 DOI
Malgorzata Jaronczyk,
Zdizlav Chilmonczyk,
AP Mazurek,
Gabriel Nowak,
aina westrheim Ravna,
kurt Kristiansen
m.fl.:
The molecular interactions of buspirone analogues with the serotonin transporter
Bioorganic & Medicinal Chemistry 2008 DOI
Aina Westrheim Ravna,
Ingebrigt Sylte,
Kurt Kristiansen,
Svein G. Dahl
:
Putative drug binding conformations of monoamine transporters
Bioorganic & Medicinal Chemistry 2006
J.D. Paasche,
T. Attramadal,
Kurt Kristiansen,
M.P. Oksvold,
H.K. Johansen,
H.S. Huitfeldt
m.fl.:
Subtype-specific sorting of the ETA endothelin receptor by a novel endocytic recycling signal for G protein-coupled receptors
Molecular Pharmacology 2005
Jack-Ansgar Bruun,
Ernst I.s. Thomassen,
Kurt Kristiansen,
Garth Daryl Tylden,
Turid Holm,
Ingvild Mikkola
m.fl.:
The third helix of the homeodomain of paired class homeodomain proteins acts as a recognition helix both for DNA and protein interactions
Nucleic Acids Research (NAR) 2005 ARKIV
HK Knutsen,
HB Ølstørn,
JE Paulsen,
T Husøy,
Ingeborg Løstegaard Goverud,
Else Marit Løberg
m.fl.:
Increased levels of PPARbeta/delta and cylin D1 in flat dysplastic ACF and adenomas in Apc(Min/+) mice
Anticancer Research 2005
Kurt Kristiansen
:
Molecular mechanisms of ligand binding, signaling, and regulation within the superfamily of G-protein-coupled receptors: molecular modeling and mutagenesis approaches to receptor structure and function
Pharmacology and Therapeutics 2004
Kaare Magne Nielsen,
Kurt Kristiansen
:
Gene conversion as a source of nucleotide diversity in Plasmodium falciparum
Molecular Biology and Evolution (MBE) 2003
Rasmus K. Petersen,
RK Petersen,
Claus Jørgensen,
C Jorgensen,
Arild C. Rustan,
Livar Frøyland
m.fl.:
Arachidonic acid-dependent inhibition of adipocyte differentiation requires PKA activity and is associated with sustained expression of cyclooxygenases
Journal of Lipid Research 2003
Trond Lamark,
maria Perander,
Heidi Outzen,
kurt Kristiansen,
Aud Karin Øvervatn,
Espen Michaelsen
m.fl.:
Interaction codes within the family of mammalian Phox and Bem1p domain-containing proteins.
Malgorzata Jaronczyk,
Zdizlav Chilmonczyk,
AP Mazurek,
M Dybala,
aina westrheim Ravna,
kurt Kristiansen
m.fl.:
Molecular mechanism of selective serotonin reuptake inhibitors (SSRI's) interactions with serotonin transporter
Journal of Peptide Science 2006
Malgorzata Jaronczyk,
Zdizlav Chilmonczyk,
AP Mazurek,
M Dybala,
aina westrheim Ravna,
kurt Kristiansen
m.fl.:
Molecular mechanism of selective serotonin reuptake inhibitors (SSRI's)interactions with serotonin transporter
2006
Olayiwola Adedotun Adekoya,
Svein G. Dahl,
Mari Gabrielsen,
Osman A.B.S.M. Gani,
Mahmud Tareq Hassan Khan,
kurt Kristiansen
m.fl.:
The molecular modelling group
2006
J.D. Paasche,
T. Attramadal,
Kurt Kristiansen,
H.K. Johansen,
Svein G. Dahl,
Håvard Attramadal
:
Structural characterization of a motif that dictates recycling of the ETA receptor via a novel molecular mechanism
Circulation 2003
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Forskningsinteresser
Struktur og funksjon av G-proteinkoblede reseptorer
Studier av legemidler og deres interaksjoner med membranproteiner.
Medlem i forskningsgruppe
Medlem i prosjekt
CV
Utdanning
1992 Cand. Scient., University of Tromsø
1997 Dr. Scient., University of Tromsø
Yrkespraksis
1997-1998 Postdoctoral fellowship, Case Western University, Cleveland, Ohio, U.S.
1998-1999 Postdoctoral fellowship from Forskerakademiet in Denmark, Danish University of Pharmaceutical Sciences, Copenhagen, Denmark
1999-2000 Postdoctoral fellowship, Institute of Medical Pharmacology, Berlin, Germany
2000-2006 Postdoctoral fellowship, Research council of Norway and Functional Genomics in northern Norway, University of Tromsø
2006-Present Associate Professor in Pharmacology, University of Tromsø