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Professor Institutt for klinisk medisin knut.t.lappegard@uit.no

Knut Tore Lappegård


Stillingsbeskrivelse

Tilknyttet forskningsgruppe Inflammasjon ved human sykdom.


  • Bjørn Ove Faldaas, Erik Waage Nielsen, Benjamin Stage Storm, Knut Tore Lappegård, Bent Aksel Nilsen, Gabriel Hanssen Kiss m.fl.:
    Real-time feedback on chest compression efficacy by hands-free carotid Doppler in a porcine model
    Resuscitation Plus 2024 ARKIV / DOI
  • Sajan Raju, Antonio Molinaro, Ayodeji Olawale Awoyemi, Silje Fjellgård Jørgensen, Peder Rustøen Braadland, Andraz Nendl m.fl.:
    Microbial-derived imidazole propionate links the heart failure-associated microbiome alterations to disease severity
    Genome Medicine 2024 ARKIV / DOI
  • Bjørn Ove Faldaas, Erik Waage Nielsen, Benjamin Storm, Knut Tore Lappegård, Ole-Jakob How, Bent Aksel Nilsen m.fl.:
    Hands-free continuous carotid Doppler ultrasound for detection of the pulse during cardiac arrest in a porcine model
    Resuscitation Plus 2023 ARKIV / DOI
  • Andraz Nendl, Sajan Raju, Kaspar Broch, Christiane Caroline Mayerhofer, Kristian Holm, Bente Halvorsen m.fl.:
    Intestinal fatty acid binding protein is associated with cardiac function and gut dysbiosis in chronic heart failure
    Frontiers in Cardiovascular Medicine 2023 ARKIV / DOI
  • Anette Krane, Gunn Pettersen, Knut Tore Lappegård, Tove Aminda Hanssen :
    In need of percutaneous coronary intervention in an arctic setting– patients’ experience of safety and quality of care: a qualitative study
    International Journal of Circumpolar Health 2023 ARKIV / DOI
  • Liv Nesse Hande, Hilde Thunhaug, Judith K Ludviksen, Anders Wilhelm Hovland, Knut Tore Lappegård :
    No effect of omega-3 polyunsaturated fatty acid supplementation on inflammatory markers in familial hypercholesterolemia: a randomized crossover trial
    Scandinavian Journal of Clinical and Laboratory Investigation 2023 ARKIV / DOI
  • Christopher Storm Larsen, Liv Nesse Hande, Martin Kummen, Hilde Thunhaug, Beate Vestad, Simen Hyll Hansen m.fl.:
    Reduced gut microbial diversity in familial hypercholesterolemia with no effect of omega-3 polyunsaturated fatty acids intervention–a pilot trial
    Scandinavian Journal of Clinical and Laboratory Investigation 2022 ARKIV / DOI
  • Kristina Barbara Slåtsve, Tor Claudi, Knut Tore Lappegård, Anne Karen Jenum, Marthe Larsen, Kjersti Nøkleby m.fl.:
    Level of education is associated with coronary heart disease and chronic kidney disease in individuals with type 2 diabetes: a population-based study
    BMJ Open Diabetes Research & Care 2022 ARKIV / DOI
  • Amalie Nilsen Hagen, Inger Kristine Holtermann Ariansen, Tove Aminda Hanssen, Knut Tore Lappegård, Anne Elise Eggen, Maja-Lisa Løchen m.fl.:
    Achievements of primary prevention targets in individuals with high risk of cardiovascular disease: an 8-year follow-up of the Tromsø study
    European Heart Journal Open (EHJ Open) 2022 ARKIV / DOI
  • Britta Susanne Bürker, Randolf Inge Hardersen, Knut Tore Lappegård :
    Symptoms of Depression, Anxiety, and Posttraumatic Stress among Patients with Cardiac Pacemakers
    International Journal of Environmental Research and Public Health (IJERPH) 2022 ARKIV / DOI
  • Liv Nesse Hande, Christian Abendstein Kjellmo, Kristin Pettersen, Stefan Ljunggren, Helen Karlsson, Karin Cederbrant m.fl.:
    Effect of N-3 Polyunsaturated Fatty Acids on Lipid Composition in Familial Hypercholesterolemia: A Randomized Crossover Trial
    Biomedicines 2022 ARKIV / DOI
  • Kristina Barbara Slåtsve, Tor Claudi, Knut Tore Lappegård, Anne Karen Jenum, Marthe Larsen, Kjersti Nøkleby m.fl.:
    Factors associated with treatment in primary versus specialist care: A population-based study of people with type 2 and type 1 diabetes
    Diabetic Medicine 2021 ARKIV / DOI
  • Ayodeji Olawale Awoyemi, Christiane Caroline Mayerhofer, Alex S. Felix, Johannes Espolin Roksund Hov, Samuel D. Moscavitch, Knut Tore Lappegård m.fl.:
    Rifaximin or Saccharomyces boulardii in heart failure with reduced ejection fraction: Results from the randomized GutHeart trial
    EBioMedicine 2021 ARKIV / DOI
  • Knut Tore Lappegård, Frode Moe :
    Remote Monitoring of CIEDs—For Both Safety, Economy and Convenience?
    International Journal of Environmental Research and Public Health (IJERPH) 2021 ARKIV / DOI
  • Knut Tore Lappegård, Christian Kjellmo, Anders Hovland :
    High-density lipoprotein subfractions: Much ado about nothing or clinically important?
    Biomedicines 18. juli 2021 ARKIV / DOI
  • Amalie Nilsen, Tove Aminda Hanssen, Knut Tore Lappegård, Anne Elise Eggen, Maja-Lisa Løchen, Randi Marie Selmer m.fl.:
    Change in cardiovascular risk assessment tool and updated Norwegian guidelines for cardiovascular disease in primary prevention increase the population proportion at risk: The Tromsø Study 2015-2016
    Open heart 2021 ARKIV / DOI
  • Leal-Costa Cesar, Antonio Lopez-Villegas, Daniel Catalan-Matamoros, Emilio Robles-Musso, Knut Tore Lappegård, Bautista-Mesa Rafael Jesus m.fl.:
    Long-Term Socioeconomic Impact of Informal Care Provided to Patients with Pacemakers: Remote vs. Conventional Monitoring
    Healthcare 2020 ARKIV / DOI
  • Remedios López-Liria, Antonio López-Villegas, César Leal-Costa, Salvador Peiró, Emilio Robles-Musso, Rafael Bautista-Mesa m.fl.:
    Effectiveness and safety in remote monitoring of patients with pacemakers five years after an implant: The Poniente study
    International Journal of Environmental Research and Public Health (IJERPH) 2020 ARKIV / DOI
  • Antonio Lopez-Villegas, Daniel Catalán-Matamoros, Salvador Peiró, Knut Tore Lappegård, Remedios Lopez-Liria :
    Cost-utility analysis of telemonitoring versus conventional hospital-based follow-up of patients with pacemakers. The NORDLAND randomized clinical trial
    PLOS ONE 2020 ARKIV / DOI
  • Anders Hovland, Kjetil Retterstøl, Tom Eirik Mollnes, Bente Evy Halvorsen, Pål Aukrust, Knut Tore Lappegård :
    Anti-inflammatory effects of non-statin low-density lipoprotein cholesterol-lowering drugs: an unused potential?
    Scandinavian Cardiovascular Journal 2020 ARKIV / DOI
  • Kristina Barbara Slåtsve, Tor Claudi, Knut Tore Lappegård, Anne Karen Jenum, Marthe Larsen, John Cooper m.fl.:
    The total prevalence of diagnosed diabetes and the quality of diabetes care for the adult population in Salten, Norway
    Scandinavian Journal of Public Health 27. august 2020 ARKIV / DOI
  • Daniel Catalán-Matamoros, Antonio Lopez-Villegas, Knut Tore Lappegård, Remedios Lopez-Liria :
    Assessing communication during remote follow-up of users with pacemakers in Norway: The Nordland study, a randomized trial
    International Journal of Environmental Research and Public Health (IJERPH) 21. oktober 2020 ARKIV / DOI
  • Remedios Lopez-Liria, Antonio Lopez-Villegas, Terje Enebakk, Hilde Thunhaug, Knut Tore Lappegård, Daniel Catalán-Matamoros :
    Telemonitoring and quality of life in patients after 12 months following a pacemaker implant: The Nordland study, a randomised trial
    International Journal of Environmental Research and Public Health (IJERPH) 2019 ARKIV / DOI
  • Amalie Nilsen, Tove Aminda Hanssen, Knut Tore Lappegård, Anne Elise Eggen, Maja-Lisa Løchen, Inger Njølstad m.fl.:
    Secular and longitudinal trends in cardiovascular risk in a general population using a national risk model: The Tromsø Study
    European Journal of Preventive Cardiology (EJPC) 2019 DOI
  • Daniel Catalán-Matamoros, Antonio Lopez-Villegas, Knut Tore Lappegård, Remedios Lopez-Liria :
    Patients' experiences of remote communication after pacemaker implant: The NORDLAND study
    PLOS ONE 2019 ARKIV / DOI
  • Randolf Inge Hardersen, Terje Enebakk, Dorte Christiansen, Judith K Ludviksen, Tom Eirik Mollnes, Knut Tore Lappegård m.fl.:
    Comparison of cytokine changes in three different lipoprotein apheresis systems in an ex vivo whole blood model
    Journal of clinical apheresis 2019 ARKIV / DOI
  • Liv Nesse Hande, Hilde Thunhaug, Terje Enebakk, Judith K Ludviksen, Kristin Pettersen, Anders Hovland m.fl.:
    Addition of marine omega-3 fatty acids to statins in familial hypercholesterolemia does not affect in vivo or in vitro endothelial function
    Journal of Clinical Lipidology 2019 ARKIV / DOI
  • Knut Tore Lappegård, Christian Kjellmo, Stefan Ljunggren, Karin Cederbrant, Maritha Marcusson-Ståhl, Monica Dammen Mathisen m.fl.:
    Lipoprotein apheresis affects lipoprotein particle subclasses more efficiently compared to the PCSK9 inhibitor evolocumab, a pilot study
    Transfusion and Apheresis Science 2018 DOI
  • Randolf Inge Hardersen, Terje Enebakk, Dorte Christiansen, Grete Bergseth, Ole-Lars Brekke, Tom Eirik Mollnes m.fl.:
    Granulocyte and monocyte CD11b expression during plasma separation is dependent on complement factor 5 (C5) ? an ex vivo study with blood from a C5-deficient individual
    APMIS - Journal of Pathologiy, Microbiology and Immunology 2018 ARKIV / DOI
  • Christiane Caroline Mayerhofer, Ayodeji Olawale Awoyemi, Samuel D. Moscavitch, Knut Tore Lappegård, Johannes Espolin Roksund Hov, Pål Aukrust m.fl.:
    Design of the GutHeart-targeting gut microbiota to treat heart failure-trial: a Phase II, randomized clinical trial
    ESC Heart Failure 2018 ARKIV / DOI
  • Antonio Lopez-Villegas, Daniel Catalán-Matamoros, Remedios Lopez-Liria, Terje Enebakk, Hilde Thunhaug, Knut Tore Lappegård :
    Health-related quality of life on tele-monitoring for users with pacemakers 6 months after implant: the NORDLAND study, a randomized trial
    BMC Geriatrics 2018 ARKIV / DOI
  • Christian Kjellmo, Helen Karlsson, Torunn Kristin Nestvold, Stefan Ljunggren, Karin Cederbrant, Maritha Marcusson-Ståhl m.fl.:
    Bariatric surgery improves lipoprotein profile in morbidly obese patients by reducing LDL cholesterol, apoB, and SAA/PON1 ratio, increasing HDL cholesterol, but has no effect on cholesterol efflux capacity
    Journal of Clinical Lipidology 2018 DOI
  • Christian Kjellmo, Anders Hovland, Knut Tore Lappegård :
    CVD Risk Stratification in the PCSK9 Era: Is There a Role for LDL Subfractions?
    Diseases 2018 DOI
  • Anne Landsem, Hilde Fure, Judith K Ludviksen, Dorte Christiansen, Corinna Lau, Monica Dammen Mathisen m.fl.:
    Complement component 5 does not interfere with physiological hemostasis but is essential for Escherichia coli-induced coagulation accompanied by Toll-like receptor 4.
    Clinical and Experimental Immunology 2018 ARKIV / DOI
  • Silje Bergland Ellingsen, Elisabet N Nordmo, Knut Tore Lappegård :
    Recurrence and severe worsening of hepatotoxicity after reintroduction of atorvastatin in combination with ezetimibe
    Clinical Medicine Insights: Case Reports 2017 DOI
  • Anders Hovland, Torunn Kristin Nestvold, Pavol Bohov, Marius Trøseid, Pål Aukrust, Rolf Kristian Berge m.fl.:
    Bariatric surgery reduces fasting total fatty acids and increases n-3 polyunsaturated fatty acids in morbidly obese individuals
    Scandinavian Journal of Clinical and Laboratory Investigation 2017 ARKIV / DOI
  • Knut Tore Lappegård, Terje Enebakk, Hilde Thunhaug, Judith K Ludviksen, Tom Eirik Mollnes, Anders Hovland :
    LDL apheresis activates the complement system and the cytokine network, whereas PCSK9 inhibition with evolocumab induces no inflammatory response
    Journal of Clinical Lipidology 2016 DOI
  • Marius Trøseid, Johannes Espolin Roksund Hov, Torunn Kristin Nestvold, Hanne Thoresen, Rolf Kristian Berge, Asbjørn M. Svardal m.fl.:
    Major increase in microbiota-dependent proatherogenic metabolite TMAO one year after bariatric surgery
    Metabolic Syndrome and Related Disorders 2016 ARKIV / DOI
  • Knut Tore Lappegård, Terje Enebakk, Hilde Thunhaug, Anders Hovland :
    Transition from LDL apheresis to evolocumab in heterozygous FH is equally effective in lowering LDL, without lowering HDL cholesterol
    Atherosclerosis 2016 DOI
  • Anders Hovland, Lena Jonasson, Peter Garred, Arne Yndestad, Pål Aukrust, Knut Tore Lappegård m.fl.:
    The complement system and toll-like receptors as integrated players in the pathophysiology of atherosclerosis
    Atherosclerosis 2015 ARKIV / DOI
  • Knut Tore Lappegård, Anna Kristina Bjerre, Geir Erland Tjønnfjord, Tom Eirik Mollnes :
    Terapeutisk komplementhemming – fra eksperimentell til klinisk medisin
    Tidsskrift for Den norske legeforening 2015 FULLTEKST / DOI
  • Corinna Lau, Ole Kristoffer Olstad, Marit Holden, Ståle Nygård, Hilde Fure, Knut Tore Lappegård m.fl.:
    Gene expression profiling of Gram-negative bacteria-induced inflammation in human whole blood: The role of complement and CD14-mediated innate immune response
    Genomics Data 2015 ARKIV / DOI
  • Knut Tore Lappegård, Hanne Bjørnstad, Tom Eirik Mollnes, Anders Hovland :
    Effect of Cardiac Resynchronization Therapy on Inflammation in Congestive Heart Failure: A Review
    Scandinavian Journal of Immunology 2015 DOI
  • Ingrid Petrikke Olsen, Ingunn Heggheim, Knut Tore Lappegård :
    Videreutvikling av desentralisert legeutdanning.Betydning for rekruttering og stabilisering
    2023
  • Bjørn Ove Faldaas, Erik Waage Nielsen, Benjamin Stage Storm, Knut Tore Lappegård, Ole-Jakob How, bent aksel nielsen m.fl.:
    Real Time Feedback of Chest Compressions by Hands-Free Carotid Doppler in a Porcine Model
    Circulation 2023
  • Bjørn Ove Faldaas, Erik Waage Nielsen, Benjamin Stage Storm, Knut Tore Lappegård, Ole-Jakob How, Bent Aksel Nilsen m.fl.:
    RescueDoppler: Non-invasive Handsfree Carotid Doppler Ultrasound For Continuous Hemodynamic-guided Resuscitation
    Circulation 2022 DOI
  • Ingrid Petrikke Olsen, Børge Lillebo, Eirik Hugaas Ofstad, Arve Østlyngen, Knut Tore Lappegård :
    Tid for å utdanne flere leger desentralt
    Tidsskrift for Den norske legeforening 2021 DOI
  • Synnøve G Mortensen, Petr Buchmann, Knut Tore Lappegård :
    Epipericardial Fat Necrosis: A Case Report and a Review of the Literature
    Clinical Medicine Insights: Case Reports 2020 ARKIV / DOI
  • Bjørn Ove Faldaas, Erik Waage Nielsen, Benjamin Stage Storm, Knut Tore Lappegård, Ole-Jakob How, Bent Aksel Nilsen m.fl.:
    Abstract 301: RescueDoppler: Non-invasive Handsfree Carotid Doppler Ultrasound For Continuous Hemodynamic-guided Resuscitation
    2020
  • Christian Kjellmo, Gheorghe Pop, Knut Tore Lappegård, Anders Wilhelm Hovland :
    Intensive lipid lowering therapy reduces large, but not small, dense low-density lipoprotein particles measured by gel electrophoresis, in elderly patients with atrial fibrillation
    European Journal of Preventive Cardiology (EJPC) 2019 DOI

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