Bilde av Larsen, Kenneth Bowitz
Foto: Kenneth Bowitz Larsen
Bilde av Larsen, Kenneth Bowitz
Senioringeniør Institutt for medisinsk biologi kenneth.larsen@uit.no +4777645320

Kenneth Bowitz Larsen


Stillingsbeskrivelse

Jeg er involvert i en rekke prosjekter der konfokalmikroskopi er sentralt for forskningen. I noen tilfeller er jeg direkte involvert i planlegging og gjennomføring av forsøk, i andre tilfeller sørger jeg for teknisk opplæring og veiledning av andre, samt databehandling.

I tillegg driver jeg metodeutvikling og utprøving av ny teknologi som kan være av interesse for brukere av kjernefasiliteten, eller som de ulike forskningsgruppene etterspør.


  • Gustav Godtliebsen, Kenneth Bowitz Larsen, Zambarlal Babanrao Bhujabal, Ida Sundvor Opstad, Mireia Nager Grifo, Abhinanda Ranjit Punnakkal m.fl.:
    High-resolution visualization and assessment of basal and OXPHOS-induced mitophagy in H9c2 cardiomyoblasts
    Autophagy 2023 ARKIV / DOI
  • Juncal Garcia Garcia, Anne Kristin McLaren Berge, Katrine Stange Overå, Kenneth Bowitz Larsen, Zambarlal Babanrao Bhujabal, Andreas Brech m.fl.:
    TRIM27 is an autophagy substrate facilitating mitochondria clustering and mitophagy via phosphorylated TBK1
    The FEBS Journal 2022 ARKIV / DOI
  • Mona Dixon Gundersen, Kenneth Bowitz Larsen, Kay-Martin Johnsen, Rasmus Goll, Jon Florholmen, Guttorm Haraldsen :
    Hypo-osmotic stress induces the epithelial alarmin IL-33 in the colonic barrier of ulcerative colitis
    Scientific Reports 2022 ARKIV / DOI
  • Thaddaeus Mutugi Nthiga, Birendra Kumar Shrestha, Jack-Ansgar Bruun, Kenneth Bowitz Larsen, Trond Lamark, Terje Johansen :
    Regulation of Golgi turnover by CALCOCO1-mediated selective autophagy
    Journal of Cell Biology 2021 ARKIV / DOI
  • Yakubu Princely Abudu, Birendra Kumar Shrestha, Wenxin Zhang, Anthimi Palara, Hanne Britt Brenne, Kenneth Bowitz Larsen m.fl.:
    SAMM50 acts with p62 in piecemeal basal- and OXPHOS-induced mitophagy of SAM and MICOS components
    Journal of Cell Biology 2021 ARKIV / DOI
  • Erik Knutsen, Seyed Mohammad Lellahi, Miriam Ragle Aure, Silje Nord, Silje Fismen, Kenneth Bowitz Larsen m.fl.:
    The expression of the long NEAT1_2 isoform is associated with human epidermal growth factor receptor 2-positive breast cancers
    Scientific Reports 2020 ARKIV / DOI
  • Katrine Stange Overå, Juncal Garcia Garcia, Zambarlal Bhujabal, Ashish Jain, Aud Karin Øvervatn, Kenneth Bowitz Larsen m.fl.:
    TRIM32, but not its muscular dystrophy-associated mutant, positively regulates and is targeted to autophagic degradation by p62/SQSTM1
    Journal of Cell Science 02. desember 2019 ARKIV / DOI
  • Birendra Kumar Shrestha, Mads Skytte Rasmussen, Yakubu Princely Abudu, Jack-Ansgar Bruun, Kenneth Bowitz Larsen, Endalkachew Ashenafi Alemu m.fl.:
    NIMA-related kinase 9–mediated phosphorylation of the microtubule-associated LC3B protein at Thr-50 suppresses selective autophagy of p62/sequestosome 1
    Journal of Biological Chemistry 2019 ARKIV / DOI
  • Gry Hoem, Kenneth Bowitz Larsen, Aud Karin Øvervatn, Andreas Brech, Trond Lamark, Eva Sjøttem m.fl.:
    The FMRpolyGlycine protein mediates aggregate formation and toxicity independent of the CGG mRNA hairpin in a cellular model for FXTAS
    Frontiers in Genetics 2019 ARKIV / DOI
  • Jakob Mejlvang, Hallvard Lauritz Olsvik, Steingrim Svenning, Jack-Ansgar Bruun, Yakubu Princely Abudu, Kenneth Bowitz Larsen m.fl.:
    Starvation induces rapid degradation of selective autophagy receptors by endosomal microautophagy
    Journal of Cell Biology 17. juli 2018 ARKIV / DOI
  • Radu Tusco, Anne-Claire Jacomin, Ashish Jain, Bridget S Penman, Kenneth Bowitz Larsen, Terje Johansen m.fl.:
    Kenny mediates selective autophagic degradation of the IKK complex to control innate immune responses
    Nature Communications 2017 ARKIV / DOI
  • Mads Skytte Rasmussen, Stephane Mouilleron, Birendra Kumar Shrestha, Martina Wirth, Rebecca Lee, Kenneth Bowitz Larsen m.fl.:
    ATG4B contains a C-terminal LIR motif important for binding and efficient cleavage of mammalian orthologs of yeast Atg8
    Autophagy 2017 DOI
  • Hallvard Lauritz Olsvik, Trond Lamark, Kenji Takagi, Kenneth Bowitz Larsen, gry Evjen, Aud Karin Øvervatn m.fl.:
    FYCO1 contains a C-terminally extended, LC3A/B-preferring LC3-interacting region (LIR) motif required for efficient maturation of autophagosomes during basal autophagy
    Journal of Biological Chemistry 2015 ARKIV / DOI
  • Elizabeth Deosaran, Kenneth Bowitz Larsen, Rong Hua, Graeme Sargent, Yuqing Wang, Sarah Kim m.fl.:
    NBR1 acts as an autophagy receptor for peroxisomes
    Journal of Cell Science 2013 DOI
  • Endalkachew Ashenafi Alemu, Trond Lamark, Knut Martin Torgersen, Åsa birna Birgisdottir, Kenneth Bowitz Larsen, Ashish Jain m.fl.:
    ATG8 Family Proteins Act as Scaffolds for Assembly of the ULK Complex SEQUENCE REQUIREMENTS FOR LC3-INTERACTING REGION (LIR) MOTIFS
    Journal of Biological Chemistry 2012 ARKIV / DOI
  • Endalkachew Alemu, Eva Sjøttem, heidi Outzen, Kenneth Bowitz Larsen, turid Holm, Geir Bjørkøy m.fl.:
    Transforming growth factor-beta-inducible early response gene 1 is a novel substrate for atypical protein kinase Cs
    Cellular and Molecular Life Sciences (CMLS) 2011 ARKIV / DOI
  • Kenneth Bowitz Larsen, Trond Lamark, Aud Karin Øvervatn, Ingvill Harneshaug, Terje Johansen, Geir Bjørkøy :
    A reporter cell system to monitor autophagy based on p62/SQSTM1
    Autophagy 2010
  • Ashish Jain, Trond Lamark, Eva Sjøttem, Kenneth Bowitz Larsen, Jane Atesoh Awuh, Aud Karin Øvervatn m.fl.:
    p62/SQSTM1 Is a Target Gene for Transcription Factor NRF2 and Creates a Positive Feedback Loop by Inducing Antioxidant Response Element-driven Gene Transcription
    Journal of Biological Chemistry 2010 DOI
  • Terje Clausen, Trond Lamark, Pauline Isakson, Kim Finley, Kenneth Bowitz Larsen, Andreas Brech m.fl.:
    p62/SQSTM1 and ALFY interact to facilitate the formation of p62 bodies/ALIS and their degradation by autophagy
    Autophagy 2010 DOI
  • Ingelin Kyrrestad, Javier Sanchez Romano, Anett Kristin Larsen, Ruomei Li, Jaione Simon-Santamaria, Kenneth Bowitz Larsen m.fl.:
    Effect of dynamin inhibitor dynasore on primary mouse liver sinusoidal endothelial cells (LSEC)
    2022
  • Martin Seem, Bjørnar Sporsheim, Per Winge, Kenneth Bowitz Larsen, Atle M. Bones :
    Selective photobleaching: The missing manual
    2012
  • Martin Seem, Bjørnar Sporsheim, Per Winge, Kenneth Bowitz Larsen, Atle M. Bones :
    Molecular imaging as a tool for studying intracellular transport
    2008
  • Atle M. Bones, Kenneth Bowitz Larsen, Torfinn Sparstad, Tone Christensen, Per Winge, Jens Rohloff :
    Microarray Services available at the Norwegian Arabidopsis Research Centre (NARC)
    2006 DATA
  • Kenneth Bowitz Larsen, Atle M. Bones :
    Molekylær analyse av COPII-komponenter i Arabidopsis thaliana
    2005

  • De 50 siste resultatene fra Cristin vises på siden. Se alle arbeider i Cristin her →


    Forskningsinteresser

    Kvantitativ mikroskopi, levende celle-mikroskopi, fluorescerende proteiner