Bilde av Wushur, Imin
Bilde av Wushur, Imin
Overingeniør Eksperimentell og klinisk farmakologi imin.wushur@uit.no +4777620975

Imin Wushur



  • Fatema Rahman, Imin Wushur, Nabin Malla, Ove Alexander Høgmoen Åstrand, Pål Rongved, Jan-Olof Winberg m.fl.:
    Zinc-Chelating Compounds as Inhibitors of Human and Bacterial Zinc Metalloproteases
    Molecules 2021 ARKIV / DOI
  • Rangita Dawadi, Nabin Malla, Beate Hegge, Imin Wushur, Eli Berg, Gunbjørg Svineng m.fl.:
    Molecular Interactions Stabilizing the Promatrix Metalloprotease-9·Serglycin Heteromer
    International Journal of Molecular Sciences 2020 ARKIV / DOI
  • Jacobus Johannes Eksteen, Dominik Ausbacher, Jaione Simon-Santamaria, Trine Stiberg, Cristiane de Albuquerque Cavalcanti Jacobsen, Imin Wushur m.fl.:
    Iterative design and in vivo evaluation of an oncolytic antilymphoma peptide
    Journal of Medicinal Chemistry 2016 DOI
  • Imin Wushur, Ingebrigt Sylte, Jan-Olof Winberg :
    The catalytic reaction mechanism of drosophilid alcohol dehydrogenases
    Perspectives in Science 2015 ARKIV / DOI
  • inger Lindin, Yimingjiang Wuxiuer, Aina Westrheim Ravna, Ugo Moens, Ingebrigt Sylte :
    Comparative molecular dynamics simulations of mitogen-activated protein kinase-activated protein kinase 5
    International Journal of Molecular Sciences 2014 ARKIV / DOI
  • Imin Wushur, Jan-Olof Winberg, Ingebrigt Sylte :
    Comparative molecular dynamic simulations of wild type and Thr114Val mutated Scaptodrosophila lebanonensis alcohol dehydrogenase
    Journal of Biomolecular Structure and Dynamics 2014 DOI
  • Olayiwola Adekoya, Stian Sjøli, Imin Wushur, Irina Bilto, Sergio M Marques, M Amelia Santos m.fl.:
    Inhibition of pseudolysin and thermolysin by hydroxamate-based MMP inhibitors
    European Journal of Medicinal Chemistry 2014 DOI
  • Yimingjiang Wuxiuer, Jan-Olof Winberg, Ingebrigt Sylte :
    Comparative molecular dynamics simulations of wild type and Thr114Val mutated Scaptodrosophila lebanonensis alcohol dehydrogenase
    Journal of Biomolecular Structure and Dynamics 2013 DOI
  • inger Lindin, Yimingjiang Wuxiuer, Irina Kufareva, Ruben Abagyan, Ugo Moens, Ingebrigt Sylte m.fl.:
    Homology modeling and ligand docking of Mitogen-activated protein kinase-activated protein kinase 5 (MK5)
    Theoretical Biology Medical Modelling 2013 ARKIV / DOI
  • Yimingjiang Wuxiuer, Ekaterina Morgunova, Neus Cols, Alexander Popov, Andrey Karshikoff, Ingebrigt Sylte m.fl.:
    An intact eight-membered water chain in drosophilid alcohol dehydrogenases is essential for optimal enzyme activity
    The FEBS Journal 2012 DOI
  • Mahmud Tareq Hassan Khan, Yimingjiang Wuxiuer, Ingebrigt Sylte :
    Binding Modes and Pharmacophore Modelling of Thermolysin Inhibitors
    Mini-Reviews in Medicinal Chemistry 2012
  • Mahmud Tareq Hassan Khan, R. Khan, Yimingjiang Wuxiuer, M. Arfan, M. Ahmed, Ingebrigt Sylte :
    Identification of novel quinazolin-4(3H)-ones as inhibitors of thermolysin, the prototype of the M4 family of proteinases
    Bioorganic & Medicinal Chemistry 2010 DOI
  • Mahmud Tareq Hassan Khan, Yimingjiang Wuxiuer, Ingebrigt Sylte :
    Molecular recognition of thermolysin and homologous zinc-metalloproteinases
    Minerva biotecnologica (Testo stampato) 2007
  • Fatema Rahman, Imin Wushur, Ingebrigt Sylte, Jan-Olof Winberg :
    Extracellular human and bacterial zinc metalloproteases – challenges in design of specific inhibitors
    NBS-nytt 2021
  • Yimingjiang Wuxiuer, N Cols, R Gonzalez-Duarte, R Ladenstein, Ingebrigt Sylte, Jan-Olof Winberg :
    Kinetic characterization of the Drosophila lebanonensis ADH T114V mutant
    The FEBS Journal 2010

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    Forskningsinteresser

    • Molecular modeling, docking and scoring, Molecular dynamic simulation, combined quantum mechanics-molecular mechanics (QMMM) studies
    • Small molecular binding assays and enzyme kinetic studies
    • Therapeutic inhibitor design to disease related human enzymes