spring 2018

BIO-3323 Bioinformatics: Genomes and genomics - 10 ECTS

Sist endret: 29.01.2019

The course is provided by

Faculty of Science and Technology

Location

Tromsø |

Application deadline

Applicants from Nordic countries: 1 June for the autumn semester and 1 December for the spring semester. Exchange students and Fulbright students: 1 October for the spring semester and 15 April for the autumn semester.

Type of course

The course is available as a singular or elective course independent of study program, also to exchange students. The course is offered on condition that a minimum number of students register for the course.

Admission requirements

Bachelor`s degree (180 ECTS) in Biology or equivalent qualification in biology. An average grade of equivalent to C or better in the Norwegian grading system is required.

Course content

Bioinformatics is a combination of biological science and information technology used in analyzing and deriving conclusions from large data sets. This course introduces the students to bacterial genomes and genome analysis. Genome-scale sequencing projects have led to an explosion of genetic information (gene sequences) available for analysis. The student will be shown how these sequences can lead to a much fuller understanding of many biological processes. The aim is to provide a practical description of the topics, tools and current trends in bacterial genomics including their impact on biology, human and veterinary medicine. Major topics will include:

  • genome sequencing and assembly
  • genome annotation (gene prediction and functional assignment)
  • prediction of binding sites
  • comparative genomics
  • Transcriptomics (RNA-seq)

-    systems biology -    phylogenetic analysis  

Recommended prerequisites

BIO-2304 Introduction to Bioinformatics

Objectives of the course

Knowledge:

The candidate:

  • has broad knowledge in genomics and genome analysis including
  • is familiar with methods and techniques applied in bioinformatics on prokaryote organisms
  • can apply bioinformatics to important areas of this field
  • can update his/her knowledge related to comparative genomics

Skills: The candidate:

  • can evaluate  information in bioinformatics and use it to work with practical and theoretical problems
  • can analyse methods, techniques and interpretations in bioinformatics and work independently on practical problems
  • can use relevant methods and techniques in bioinformatics based on well-founded choises
  • can carry out a  limited research project under supervision.

General competence: The candidate:

  • can apply her/his knowledge and skills in bioinformatics in order to carry out assignments and projects
  • can communicate terminology in the field of bioinformatics
  • can communicate about academic issues, analyses and conclusions in the field of bioinformatics

Language of instruction

The language of instruction is English and all syllabus material is in English

Teaching methods

The course will be taught as a combination of lectures, demonstrations and practical lab work. Lectures and hands-on laboratory exercises: 80 h.  

Assessment

Evaluation of orally presented report. Pass/not pass.

Candidates who fail the exam can register for re-sit the following semester.

Date for examination

One oral test 27.04.2018

The date for the exam can be changed. The final date will be announced in the StudentWeb early in May and early in November.

Schedule

Course overlap

KJE-8602 Bioinformatics - genome and genome analysis 8 stp

Recommended reading/syllabus

Curriculum is lectures and laboratory booklet.