Centre for New Antibacterial Strategies (CANS) seminar

Major advances have been made during the past years of how microbes are cultured for natural products discovery. This has resulted in the discovery of novel antibacterial molecules. Most of the new culturing techniques aiming to trigger the growth of previously uncultured microbes with putatively novel natural products or activate silent biosynthetic gene clusters of cultivable microbes have been applied to bacteria. This presentation focuses on fungi and summarizes techniques tested to increase their cultivability and production of secondary metabolites