Disputas- Cand. med Carl Arne Løchen Arnesen

Avhandlingen er tilgjengelig her! The doctoral thesis! Prøveforelesning over oppgitt emne holdes kl. 10.15, samme sted: “The value of risk factors for a first VTE in the decision on the duration of anticoagulant treatment and predicting recurrent thrombosis”.  Prøveforelesningen vil også bli strømmet/the trail lecture will also be streamed. Disputasen starter kl. 1215  og vil bli strømmet her! Opptak av disputasen vil være tilgjengelig i et døgn. The defense will be streamed here.  A recording of the disputation will be available for 24 hours.

Populærvitenskapelig sammendrag av avhandlingen:

Venous thromboembolism (VTE) is a serious condition that affects both men and women. However, past studies have reported conflicting results on the sex-specific risk of VTE. 
Using Danish national registries, we examined the lifetime VTE risk in men and women. Also, using data from the Tromsø and Trøndelag health studies, we investigated whether certain risk factors affected men and women differently. We studied the sex-specific proportion of VTE events attributable to prothrombotic genotypes, and the impact of body height on VTE risk in men and women.

We found that women had a slightly higher lifetime VTE risk than men, but accounting for pregnancy and oral contraceptives equalized the risk. We also found that 52% of VTE events in men and 38% in women were linked to prothrombotic genotypes. Finally, taller stature was a risk factor for both sexes, with a more substantial effect observed in men. 
This thesis provides insight into the lifetime risk of VTE in men and women and increases current knowledge on sex-specific epidemiology and risk factors.

Hovedveileder
Professor Sigrid Kufaas Brækkan, Institutt for klinisk medisin, Det helsevitenskapelige fakultet, UiT Norges arktiske universitet. 

Biveileder
Professor John Bjarne Hansen, Institutt for klinisk medisin, Det helsevitenskapelige fakultet, UiT Norges arktiske universitet

Bedømmelseskomité
Førsteamanuensis, Astrid van Hylckama Vlieg, Leiden University Medical Centre - 1. opponent.
Førsteamanuensis Marcus Lind, Umeå universitet – 2. opponent.
Professor Trond Flægstad, Institutt for klinisk medisin, Det helsevitenskapelige fakultet, UiT Norges arktiske universitet - leder av komité.

Disputasleder: Førsteamanuensis Åsa Birna Birgisdottir, Institutt for klinisk medisin, Det helsevitenskapelige fakultet, UiT Norges arktiske universitet.