Master of science Rabiul Hasan will Thursday September 14th, 2023, at 12:15 hold his disputas for the PhD degree in Science. The title of his thesis is:
"Dielectric nanoantennas and metasurfaces for optical trapping"
Analysis of biological nanoparticles in medical sciences is very promising, as it can reveal groundbreaking information about disease mechanisms, potentially leading to innovative and more effective treatment strategies. The existing methods used for analyzing biological nanoparticles come with several limitations, involving extensive sample preparation, and giving limited information about the nanoparticles. Optical tweezers combined with Raman spectroscopy is an analytical technique that has opened new possibilities for chemical analysis of biological nanoparticles. Currently used Raman optical tweezers are restricted to capturing Raman spectra from a single or a few nanoparticles and a large number of measurements are necessary to obtain valid statistics, giving low throughput analysis. Thus, development of new techniques is necessary for high-throughput chemical analysis of biological nanoparticles. The presented thesis uses numerical simulation to investigate two types of dielectric nanostructures for on-chip optical trapping and Raman spectroscopy. The aim is to find a suitable structure for high throughput analysis of multiple extracellular vesicles (EVs), a type of biological nanoparticle released from various cells. The technique relies on using the near-visible laser to trap and excite Raman scattering from the EVs.
Evaluation Committee
Supervisors
Streaming site
The disputas and trial lecture will be streamed from these sites:
Disputas (12:15 - 16:00)
Trial Lecture (10:15 - 11:15)
Thesis
The thesis is available through Munin.