Nora Ness

Avhandlingen er tilgjengelig her! / The doctoral thesis is available here!



På grunn av koronautbruddet er auditoriet stengt for publikum. Disputasen og prøveforelesningen blir strømmet. Opptaket av disputasen vil være tilgjengelig i et døgn.
The auditorium will be closed to the public because of the corona outbreak. The defense and the trial lecture will be streamed. A recording of the disputation will be available for 24 hours.


Prøveforelesning over oppgitt emne starter kl. 10.15 / The trial lecture starts at 10.15
Tittel/Title: "Overview of inflammatory diseases with respect to cancer development."
Prøveforelesningen strømmes her / The trial lecture will be streamed here

Disputasen starter kl. 12.15 / The defense starts at 12.15
Disputasen strømmes her / The defense will be streamed here

De som ønsker å opponere ex auditorio kan sende e-post til leder av disputasen. 
Opponents ex auditorio should sign up to leader of defense by e-mail to:
ole.l.brekke@uit.no

 
Populærvitenskapelig sammendrag av avhandlingen/ Summary of the thesis

In Norway, prostate cancer is the most commonly diagnosed cancer, with almost 5000 new affected individuals every year. However, whilst some patients have a very aggressive course with a fatal outcome, the majority of patients have slow-growing disease with low risk of death or significant symptoms. Unfortunately, doctors do not possess sufficient prognostic tools to give each patient a satisfactory risk assessment, and thus, there is a high risk of overtreatment with unnecessary side-effects.

In a quest to find new prognostic tools, we analyzed different immune system components, including components known to be important in cancer immunotherapy, in 535 surgically removed prostate cancers.

Our discoveries indicate that a high amount of some immune system components in prostate cancer tumors may predict a more aggressive disease development. Further research is needed to verify if this information can be relevant for patients in either a prognostic- and/or treatment aspect.

 
Veiledere/ Supervisors:
Hovedveileder/Main supervisor:
Professor Elin Richardsen, Institutt for medisinsk biologi, Det helsevitenskapelige fakultet, UiT Norges arktiske universitet.
Biveiledere/supervisors:
Professor/overlege i patologi Lill-Tove Rasmussen Busund, Institutt for medisinsk biologi, Det helsevitenskapelige fakultet, UiT Norges arktiske universitet.
Postdoctor Sigve Andersen (Ph.D), Institutt for klinisk medisin, Det helsevitenskapelige fakultet, UiT Norges arktiske universitet.

Bedømmelseskomité/Defensecomitee:
Professor Marene Landström, Umeå Universitet – 1. opponent.
Førsteamanuensis Åsmund Flobak, NTNU – 2. opponent.
Forsker Synnøve Magnussen, Institutt for medisinsk biologi, Det helsevitenskapelige fakultet, UiT Norges arktiske universitet – leder av komité.

Disputasleder/ Leader of defense:
Professor Ole-Lars Brekke, Institutt for klinisk medisin, Det helsevitenskapelige fakultet, UiT Norges arktiske universitet.