Olena Iakunchykova

Avhandlingen er tilgjengelig her! / The doctoral thesis is available here!

Disputasen og prøveforelesningen blir strømmet. Opptak av disputasen vil være tilgjengelig i en måned.
The defense and the trial lecture will be streamed. A recording of the disputation will be available for one month.

Prøveforelesning over oppgitt emne starter kl. 10.15 / The trial lecture starts at 10.15
Tittel/Title:  “The role of low and high density lipoproteins in cardiovascular diseases – causal factors or innocent bystanders?”
Prøveforelesningen strømmes her / The trial lecture will be streamed here

Disputasen starter kl. 12.15 / The defense starts at 12.15
Disputasen strømmes her / The defense will be streamed here

De som ønsker å opponere ex auditorio kan sende e-post til leder av disputasen. 
Opponents ex auditorio should sign up to leader of defense by e-mail to:
anne-sofie.furberg@uit.no

 
Populærvitenskapelig sammendrag av avhandlingen/ Summary of the thesis

My PhD thesis contributes to understanding why Russia has a high burden of cardiovascular disease.  To do this I have compared participants aged 40-69 years from two studies: Know Your Heart (Arkhangelsk and Novosibirsk, Russia) and Tromsø 7 (Norway).
There were no substantial differences in cholesterol levels between them. However, participants in the Russian study had higher levels of general inflammation and markers of heart damage compared to Norwegians. Much higher levels of diagnosed and undiagnosed diabetes were also found in Russia, which for women was largely explained by Russian women having higher body mass index. I also found evidence of heart damage related to heavy alcohol use.
In conclusion, at working ages there is more heart damage in Russia than Norway that cannot be explained by high levels of cholesterol. This excess of non-atherosclerotic disease will be explained by a number of factors of which hazardous drinking is only one.

Veiledere/ Supervisors:
Hovedveileder/Main supervisor:
Professor David Andrew Leon, London School of Hygiene & Tropical Medicine,
Institutt for samfunnsmedisin, Det helsevitenskapelige fakultet, UiT Norges arktiske universitet and
International Laboratory for Population and Health, National Research University, Higher School of Economics, Moscow

Biveiledere/supervisors:
Professor Tom Wilsgaard, Institutt for samfunnsmedisin, Det helsevitenskapelige fakultet, UiT Norges arktiske universitet
Forsker Maria Averina, Institutt for samfunnsmedisin, Det helsevitenskapelige fakultet, UiT Norges arktiske universitet. Overlege, Laboratoriemedisin, Universitetssykehus i Nord Norge.

Bedømmelseskomité/Defensecomitee:
Professor Deborah Lawlor, Bristol Population Health Science Institute, Bristol Medical School, University of Bristol, UK – 1. opponent
Professor Tom Ivar Lund Nilsen, Department of public health and nursing, NTNU, Norway - 2. opponent
Professor Inger Njølstad, Institutt for samfunnsmedisin, Det helsevitenskapelige fakultet, UiT Norges arktiske universitet – leder av komité

Disputasleder/ Leader of defense:
Professor Anne-Sofie Furberg, Institutt for samfunnsmedisin, Det helsevitenskapelige fakultet, UiT Norges arktiske universitet