cand.med. Jostein Lappegård disputerer for ph.d.-graden i helsevitenskap og vil offentlig forsvare avhandlingen:
“RedCell Distribution Width (RDW) and future risk of arterial cardiovascular diseases. ”
Kort sammendrag av avhandlingen:
Heart attack and stroke are the top two deadliest diseases worldwide. Awareness and treatment of known risk factors is an important step to prevent the development of these diseases. Additionally, identification of new risk factors could further improve the disease prevention. We have investigated whether a measure of the variability in the size of the red blood cells (RDW) could be such a risk factor. We used data from the Tromsø study, where RDW was measured in >27,000 inhabitants. We found that the study participants with high values of RDW, measured in 1994/95, had a higher risk of developing atherosclerosis, stroke and heart attack, compared to those with low RDW values. We also found that the disease risk associated with high RDW values was independent of known risk factors including high cholesterol, hypertension, diabetes and smoking. This means that RDW could be used, alongside other risk factors, when evaluating future risk of cardiovascular disease.
(Avhandlingen er tilgjengelig for utlån hos Seksjon forutdanningstjenester frem til disputasdato)
Veiledere
Hovedveileder: professor John-Bjarne Hansen, Institutt for klinisk medisin, UiT Norges arktiske universitet.
Biveileder: førsteamanuensis Sigrid K. Brækkan, Institutt for klinisk medisin, UiT Norges arktiske universitet
Bedømmelseskomiteen
1. Opponent: Professor Klas Gunnar Engström, Department of Clinical Science in Malmö, Lund University, Malmö, Sweden.
2. Opponent: Professor Ottar Nygård, Universitetet i Bergen
Leder av komite: Forsker Ekaterina Sharashova, Institutt for Samfunnsmedisin, Det helsevitenskapelige fakultet, UiT Norges arktiske universitet.
Disputasleder
Professor Trond Flægstad, Institutt for klinisk medisin, UiT Norges arktiske universitet
Prøveforelesning over oppgitt emne holdes kl. 10.15, samme sted: “'Inflammation in atherosclerosis – causative or protective?”