Disputas - cand.med. Jon Viljar Norvik

Cand.med. Jon Viljar Norvik disputerer for ph.d.-graden i helsevitenskap og vil offentlig forsvare avhandlingen:


Uric acid and adiponectin in cardiovascular disease


Kort sammendrag av avhandlingen:

Uric acid is constantly produced in the body and excreted by the kidney. Too much may inflict gout. Adiponectin is a hormone produced by fat tissue, and is involved in numerous metabolic processes. This project used data from the Tromsø surveys to study the roles of uric acid and adiponectin in cardiovascular disease.  We found that high uric acid levels predicted the development of elevated blood pressure and elevated fasting glucose in overweight, but not normal-weight, people. We also discovered that people with diastolic dysfunction (stiff hearts that do not relax properly) on echocardiography, had higher risk of death and stroke with increasing uric acid levels. Additionally, we found an association between low adiponectin levels and the presence of diastolic dysfunction in women, but not in men. Elevated uric acid levels are easily treatable if it proves to be a risk factor for cardiovascular disease. Why low adiponectin is associated with diastolic dysfunction in women only warrants further research.


Hovedveileder professor Kirsti Ytrehus

Biveileder førsteamanuensis II/overlege Marit Dahl Solbu



Professor Peter Rossing, Århus Universitet, Danmark - 1. opponent

Professor Serena Tonsatd, Oslo Universitetssykehus og Loma Linda University, USA - 2. opponent

Førsteamanuensis Hege Sagstuen Haugnes, Institutt for klinisk medisin, Det helsevitenskapelige fakultet, UiT – Norges arktiske universitet – leder av komiteen



Professor Ørjan Olsvik, Institutt for medisinsk biologi, Det helsevitenskapelige fakultet, UiT – Norges arktiske universitet


Prøveforelesning over oppgitt emne holdes kl. 10.15 samme dag og sted.

Når: 20.04.17 kl 12.15–16.00
Hvor: Aud 7, MH-bygget
Sted: Tromsø
Målgruppe: alle
Ansvarlig: Kristin Lagesen
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